서울숲 공원관리조직의 사회 연결망 분석

최선주,황원실,김선희,박창석,Choi, Sun-Ju,Hwang, Won-Sil,Kim, Sun-Hee,Park, Chang-Sug 한국조경학회 2011 韓國造景學會誌 Vol.39 No.3

본 연구는 공원관리 참여조직간의 사회적 연결망을 분석하고, 참여조직의 활동을 활성화하는 방향을 모색하기 위한 것이다. 이를 위해서 공원관리 참여조직 간의 신뢰, 참여, 정보교류의 실태를 사회 연결망 분석을 통해 살펴보았다. 구체적으로 서울숲을 대상으로 하였으며, 행정기관, 시민단체, 주민단체, 기업으로 구성된 15개 참여조직과 핵심인물 30명을 조사대상으로 선정하였다. 설문조사는 조직간 신뢰, 참여, 정보교류 및 연구 통계적 속성에 관한 내용으로 구성되었으며, 분석은 사회 연결망 분석 프로그램인 UCINET을 활용하였다. 분석결과, 1) 신뢰, 참여, 정보교류의 연결구조에서 다른 조직에 비해 많은 관계를 유지하고 있는 중추조직(HUB)는 서울숲 사랑모임과 서울숲 관리사무소로 나타났다. 2) 함께 일하고 싶은 조직과 향후 활발한 참여를 바라는 조직에 대한 연결망 분석에서는 환경 예술분야의 시민단체에 대한 요구가 높게 나타났다. 3) 부녀회, 통장단 등 지역 주민단체 연결망을 살펴보면 중심성이 매우 낮으며 서로간의 연결관계도 거의 없는 것으로 나타났다. 본 연구결과와 함께 다양한 도시공원과 지역을 대상으로 공원관리 참여조직간의 사회 연결망 실태를 파악함으로써 주민참여와 협력 이 활발한 공원관리 방안을 마련하는데 활용할 수 있다. This study was intended to devise means to encourage participation for organizations taking part in "resident participation parks.", "Resident participation" has become increasingly recognized as an effective means of park management in Korea. To this end, this study analyzed the current status of social networks for civic organizations participating in park management with respect to their degree of participation, credibility and trust, and exchange of information. Among resident participation parks, "Seoul Forest Park" has been widely recognized as a model example; accordingly this study designated Seoul Forest Park as its primary research focus. Thirty core members of resident participation organizations were selected as test subjects. Members of the resident participation organizations under review came from various backgrounds, including government administrative organizations, citizens' groups, residents' groups, and private businesses. Surveys were used to provide data on credibility and trust between organizations, levels of participation, and exchange of information, as well as statistics on demographic affiliation. Results were examined through UCINET, a program designed to analyze social networks. Survey results indicated that 1) The "Seoul Forest Park Conservancy" and the "Seoul Forest Park Management Office" constituted a hub within their social networks that maintained significantly more relationships than other organizations with regard to levels of credibility and trust, participation, and exchange of information; 2) Social networks for organizations wishing to work together, or desiring active participation in the future tended to center on citizens' organizations in the environmental and arts fields; and 3) Women's associations and meetings of neighborhood("tong") leaders had very little significance as a center in the social networks of local residents groups, and indeed very few connections amongst themselves. The results of this research can be applied in the devising of proposals for encouraging participation in resident participation parks in consideration of the social networks between organizations engaging in park management activities for a diverse array of urban parks and other areas.

OVA로 유도된 생쥐 모델에서 EGCG의 천식 예방 효과

박성남,이찬우,이창민,정만홍,황순철,박영민 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2

Epigallocatechin-3-gallate (EGCG), a major form of tea epicatechin, has a variety of biological activities. It has recently been studied intensively as an antiallergic and anti-inflammatory agent. Thus we elucidated the anti-allergic effect of EGCG in the ovalbumin (OVA)-induced asthma model mice by examining the expression of matrix metalloproteinase (MMP)-9. Also airway reactivity to methacholine challenge and reactive oxygen species (ROS) generation in BAL fluid. mesured by the expression of iNOS mRNA in lung tissue and tumor necrosis factor (TNF) in BAL fluids. The OVA challenged mice showed allergic airway reactions, such as inflammatory chemokine (CCL5,CXCL10) in the airway and lung tissues. However mice administrated with EGCG had significantly reduced CCL5 and MMP-9 expression in lung tissues as well as TNF-α and IL-5 production in BAL fluid. these results suggest that EGCG regulate

Clinical Experiences and Usefulness of Cervical Posterior Stabilization with Polyaxial Screw-Rod System

Hwang, In-Chang,Kang, Dong-Ho,Han, Jong-Woo,Park, In-Sung,Lee, Chul-Hee,Park, Sun-Young The Korean Neurosurgical Society 2007 Journal of Korean neurosurgical society Vol.42 No.4

Objective : The objective of this study is to investigate the safety, surgical efficacy, and advantages of a polyaxial screw-rod system for posterior occipitocervicothoracic arthrodesis. Methods : Charts and radiographs of 32 patients who underwent posterior cervical fixation between October 2004 and February 2006 were retrospectively reviewed. Posterior cervical polyaxial screw-rod fixation was applied on the cervical spine and/or upper thoracic spine. The surgical indication was fracture or dislocation in 18, C1-2 ligamentous injury with trauma in 5, atlantoaxial instability by rheumatoid arthritis (RA) or diffuse idiopathic skeletal hyperostosis (DISH) in 4, cervical spondylosis with myelopathy in 4, and spinal metastatic tumor in 1. The patients were followed up and evaluated based on their clinical status and radiographs at 1, 3, 6 months and 1 year after surgery. Results : A total of 189 screws were implanted in 32 patients. Fixation was carried out over an average of 3.3 spinal segment (range, 2 to 7). The mean follow-up interval was 20.2 months. This system allowed for screw placement in the occiput, C1 lateral mass, C2 pars, C3-7 lateral masses, as well as the lower cervical and upper thoracic pedicles. Satisfactory bony fusion and reduction were achieved and confirmed in postoperative flexion-extension lateral radiographs and computed tomography (CT) scans in all cases. Revision surgery was required in two cases due to deep wound infection. One case needed a skin graft due to necrotic change. There was one case of kyphotic change due to adjacent segmental degeneration. There were no other complications, such as cord or vertebral artery injury, cerebrospinal fluid leak, screw malposition or back-out, or implant failure, and there were no cases of postoperative radiculopathy due to foraminal stenosis. Conclusion : Posterior cervical stabilization with a polyaxial screw-rod system is a safe and reliable technique that appears to offer several advantages over existing methods. Further biomechanical testings and clinical experiences are needed in order to determine the true benefits of this procedure.

Original Article : Morphologic Characteristics of the Outer Retina in Cone Dystrophy on Spectral-domain Optical Coherence Tomography

( Soo Chang Cho ),( Se Joon Woo ),( Kyu Hyung Park ),( Jeong Min Hwang ) 대한안과학회 2013 Korean Journal of Ophthalmology Vol.27 No.1

Purpose: To investigate the morphologic changes in the outer retina of patients with cone dystrophy, using spectral-domain optical coherence tomography (SD-OCT). Methods: The medical records of 15 cone dystrophy patients examined from January 2007 to January 2012 were reviewed retrospectively. All patients underwent ophthalmic evaluation including best-corrected visual acuity (BCVA), color vision testing, fundus examination, full-field standard electroretinography (ERG), multifocal (mf) ERG, and SD-OCT. Qualitative and quantitative SD-OCT data and ERG responses were analyzed and compared among the patient categories and the normal control group. Results: There were 4 major categories of SD-OCT findings, based on the status of the ellipsoid portion of the photoreceptor inner segment (ISe), outer segment (OS) contact cylinder, and retinal pigment epithelium (RPE) layer. Category 0 showed no structural abnormalities. Category 1 showed foveal ISe loss and obscurity of the border between the ISe band and the external limiting membrane (ELM). Category 2 showed foveal thinning and focal foveal ISe disruption with an intact ELM. Category 3 showed foveal thickening and perifoveal disruption of the ISe layer. Category 1 to 3 showed OS contact cylinder layer absence and RPE thickening. The patients in category 0 tended to be younger (mean, 10.0 years) than those in categories 1 to 3 (mean, 17.6 years), although this difference was not statistically significant. Category 1 to 3 patients exhibited statistically significant thinning of the central retina and outer nuclear layer and thickening of the RPE layer relative to the category 0 and normal control group. There was a significant correlation between the central foveal thickness and BCVA in the patients with cone dystrophy. ERG and mfERG responses did not differ significantly among the different cone dystrophy categories. Conclusions: The morphologic features of cone dystrophy as revealed by SD-OCT, could be categorized as either normal or 1 of 3 different types of outer retinal changes. The presence of normal retinal structures in young cone dystrophy patients with functional impairment (category 0) indicates that electrophysiologic studies are superior to current imaging modalities for the early diagnosis of cone dystrophy. The characteristic SDOCT findings in cone dystrophy patients may aid in differential diagnosis and be useful for future research on the pathology of cone dystrophy.

간벌에 의한 서식지 구조와 양서,파충류 개체군의 특성 차이

박창득 ( Chang Deuk Park ),정지화 ( Ji Hwa Jung ),손승훈 ( Seung Hun Son ),황현수 ( Hyun Su Hwang2 ),이우신 ( Woo Shin Lee ) 한국임학회 2016 한국산림과학회지 Vol.105 No.2

본 연구는 간벌에 따른 서식지 구조와 양서·파충류 개체군 특성 차이를 파악하기 위해 2014년과 2015년 의 6월부터 9월까지 강원도 홍천군 매화산의 침엽수림과 활엽수림에서 각각 실시되었다. 산림의 수직구조를 파악한 결과, 모든 임상에서 간벌 이후 산림환경이 구조적으로 크게 변화하였다. 특히 간벌 후 중층 및 하층의 피도량이 감소한 반면, 도목잔존물의 수와 부피는 증가하는 경향을 보였다. 침엽수림과 활엽수림에 각각 2개 조사구, 총 4개 조 사구 내에서 간벌 전과 후 월별 1회씩 총 32번의 선형횡단조사를 통해 양서류는 5종 119개체, 파충류는 3종 5개체 가 확인되었다. 임상별 관찰된 평균 종수 및 개체수 차이를 파악한 결과, 침엽수림에서는 양서류의 평균 종수가 간벌 후 감소한 것으로 나타났으며, 특히 참개구리(Pelophylax nigromaculatus)와 북방산개구리(Rana dybowskii) 등 2종 이 차이를 보였다. 파충류는 관찰 간벌 후 모든 임상에서 관찰되지 않았다. 향후 간벌에 따른 양서·파충류의 개체 군 특성 차이를 파악하기 위해서는 간벌의 규모와 빈도, 강도 등 다양한 요인을 고려한 정밀 연구가 필요할 것으로 생각된다. This study was conducted to clarify the differences in habitat structure and amphibian and reptile (herpetofauna) populations between before and after thinning in the coniferous and deciduous forests from June to September 2014 and 2015 at the Mt. Maewha of Hongcheon, Gangwon province, Korea. Forest structure was dramatically changed after thinning. Coverage of understory and mid-story were decreased while volume and number of downed trees were increased after thinning. We used line transect sampling method on a total of 4 transect lines, 2 lines in each forest type. 119 individuals of 5 amphibian species and 5 individuals of 3 reptile species were recorded. Mean number of amphibian species were decreased after thinning in the coniferous forest. There was no observed reptiles after thinning in the coniferous and deciduous forests. Detailed monitoring with different area, frequency and intensity might be needed to clarify more precise differences characterisitics of herpetofauna by thinning.

폐암환자에서 발생한 Clostridium difficile 대장염의 임상적 특성

( Chul Park1 ),( Ki Eun Hwang ),( Do Sim Park ),( Yu Ri Hwang ),( Chang Hwan Seoul ),( Hak Ryul Kim ),( Eun Taik Jeong ) 대한내과학회 2011 대한내과학회 추계학술대회 Vol.2011 No.-

High efficient rice transformation method by modifying co-cultivation conditions

Hyang-Mi Park,Yul-Ho Kim,Tae-Young Hwang,Chang In Yang,Ji Ung Jeung,Young Chan Cho,Kyoung Ho Kang,Chung-Kon Kim 한국육종학회 2012 한국육종학회 심포지엄 Vol.2012 No.07

Rice transformation method using A. tumefaciens has already been widely used to generate transgenic plants, the transformation rate is still low in most Korean elite cultivars. We made several modifications of the standard protocol especially in the co-cultivation step to improve the efficiency of the rice transformation. The co-culture medium was modified by the addition of three antioxidant compounds (10.5㎎/ℓ L-cysteine, 1mM sodium thiosulfate, 1mM dithiothreitol) and of Agrobacterium growth-inhibiting agent (5㎎/ℓ silver nitrate). Co-cultivation temperature (23. 5℃ for 1 day, 26.5℃ for 6 days) and duration (7 days) were also changed. The plasmid of pMJC-GB-GUS carrying the GUS reporter gene and the bar gene as the selectable marker was used to evaluate the efficiency of the transformation. After co-cultivation, a high level of GUS gene expression was observed in calli treated with the modified method. It is likely that those newly added compounds helped to minimize the damage due to oxidative bursts during plant cell-Agrobacterium interaction and to prevent necrosis of rice cells. And the transformation rate under the modified method was also remarkably increased approximately 8-fold in Heungnambyeo and 2-fold in Ilmibyeo as compared to the corresponding standard method. Furthermore, we could produce the transgenic plants stably from Ilpumbyeo which is a high-quality rice but its transformation rate is extremely low. Transformation and the copy number of transgenes were confirmed by PCR, bar strip and Southern blot analysis. The improved method would attribute reducing the effort and the time required to produce a large number of transgenic rice plants.

서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

A Case of Occupational Hypersensitivity Pneumonitis Associated with Trichloroethylene

Jae, Young,Hwang, Eu Dong,Leem, Ah Young,Kang, Beo Deul,Chang, Soo Yun,Kim, Ho Keun,Park, In Kyu,Kim, Song Yee,Kim, Eun Young,Jung, Ji Ye,Kang, Young Ae,Park, Moo Suk,Kim, Young Sam,Kim, Se Kyu,Chang, The Korean Academy of Tuberculosis and Respiratory 2014 Tuberculosis and Respiratory Diseases Vol.76 No.2

Trichloroethylene (TCE) is a toxic chemical commonly used as a degreasing agent, and it is usually found in a colorless or blue liquid form. TCE has a sweet, chloroform-like odor, and this volatile chlorinated organic chemical can cause toxic hepatitis, neurophysiological disorders, skin disorders, and hypersensitivity syndromes. However, the hypersensitivity pneumonitis (HP) attributed to TCE has rarely been reported. We hereby describe a case of HP associated with TCE in a 29-year-old man who was employed as a lead welder at a computer repair center. He was installing the capacitors on computer chip boards and had been wiped down with TCE. He was admitted to our hospital with complaints of dry coughs, night sweats, and weight losses for the past two months. HP due to TCE exposure was being suspected due to his occupational history, and the results of a video-associated thoracoscopic biopsy confirmed the suspicions. Symptoms have resolved after the steroid pulse therapy and his occupational change. TCE should be taken into consideration as a potential trigger of HP. Early recognition and avoidance of the TCE exposure in the future is important for the treatment of TCE induced HP.

Characterization of changes in global gene expression in the brain of neuron-specific enolase/human Tau23 transgenic mice in response to overexpression of Tau protein.

Woo, Jong-Min,Park, So Jung,Kang, Ho Il,Kim, Byoung Guk,Shim, Sun Bo,Jee, Seung Wan,Lee, Su Hae,Sin, Ji Soon,Bae, Chang Joon,Jang, Mee Kyung,Cho, Chunghee,Hwang, Dae Youn,Kim, Chuel Kyu D.A. Spandidos 2010 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE Vol.25 No.5

<P>Tau is a neuronal phosphoprotein responsible for the formation of the neurofibrillary tangles in Alzheimer's disease. To characterize the changes in global gene expression in the brain of transgenic mice that overexpress human Tau23 protein in response to the increase of Tau23 phosphorylation, total RNA extracted from the hippocampus of 12-month-old transgenic and wild-type mice was converted to cDNA, labeled with biotin and hybridized to oligonucleotide microarrays. The microarray results were confirmed by real-time RT-PCR and Western blotting method. It was determined that 43 genes were up-regulated and 8 genes were down-regulated by Tau23 in transgenic mice compared to controls, based on the arbitrary difference in the 2-fold change. Among the up-regulated transcripts, those encoding for transporter and oxidoreductase were dramatically over-represented, followed by those related to regulatory molecule, cytoskeletal protein, signaling molecule, and extracellular matrix protein. Genes encoding for transcription factor, regulatory molecule, miscellaneous function, and chaperone were significantly reduced in the down-regulated group. The major genes in the up-regulated categories included Ecrg4, Folr1, Defb11, Aqp1 and Soctdc1. The major genes in the down-regulated categories were Ncor1, Gpm6a, and Hspd1. These results indicate that the microarray analysis identifies several gene functional groups and individual genes that respond to a sustained increase in Tau23 phosphorylation levels in the brain of transgenic mice. In addition, the results suggest the microarray test is a useful tool for increased understanding of the role of Tau23 protein in regulating neurodegenerative disorders.</P>