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Two Cases of Fibrous Obliteration of the Appendix, Mimicking Acute Appendicitis
최선주,장윤진,이다근,조승현,김갑철,배지혜,박진영,천재민 대한영상의학회 2014 대한영상의학회지 Vol.70 No.6
Acute appendicitis is the most frequent appendiceal disease, but some chronic inflammatory conditions can mimic it on computed tomography (CT). We recently experienced two rare cases of appendiceal conditions, which were uncommon to our radiologists and clinicians. This condition is called fibrous obliteration of the appendix, which is a condition that involves replacement of the mucosa and submucosa with fibrotic tissues. Due to similar clinical symptoms and CT findings, fibrous obliteration of the appendix can easily be mistaken as an acute appendicitis. Here, we introduce the symptoms, laboratory results, CT findings, and histological examination findings of two adult patients with fibrous obliteration of the appendix.
Preparation and characterization of fractionized chitosan and its application for green tide
최선주,김태훈,정경원,이현수,김원석,최창용,최수경,김성초,나재운 한국공업화학회 2015 한국공업화학회 연구논문 초록집 Vol.2015 No.0
The purpose of this study is to investigate the characterization and application of fractionated chitosan by ultrafiltration method. The distribution of molecular weight was measured by GPC and the physicochemical properties of fractionized chitosan were investigated by 1H NMR, FT-IR, DSC, and TGA. This study, we take advantage of fractionized chitosan to remove harmful algae. We harvested chitosan with accurate molecular weights, narrow molecular weight distribution and high purity. These results introduced that the chitosan can be applied to the various field such as treatment of fresh water and biomedical fields. **This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Ministry of Science, ICT & Future Planning. (NRF-2014R1A2A1A10053027).
How the L2 LSTM language model predicts island effects
최선주,김유희 동국대학교 동서사상연구소 2021 철학·사상·문화 Vol.- No.36
In this paper, we investigate how well L2 language models learn about particular types of controlled contexts that indicate representation of syntactic dependencies (e.g., the filler-gap dependency and possessive pronoun gender expectation). Building the three language models, we assess LM’s knowledge by comparing the interaction in island configurations to that in non-island minimal paris. In so doing, we provide new evidence that L2 models cannot significantly maintain their expectations through island constructions while L1 model is able to thread expectations within islands. Furthermore, L2 models fail to correctly learn about empty syntactic positions while L1 model is able to generalize about them. Additionally, we control the amount of training data for L2 models to examine the correlation of the LM’s performances. However, we cannot investigate the correlation between the size of sentences that L2ers learn and their sentence processing patterns. Previous study is inconclusive about whether L2ers learn these linguistic constraints. Here, using new methodology, we show evidence about the characteristics of L2ers’ behavior.
암세포 내로의 약물 전달 증진 목적의신규 소마토스타틴 수용체 타겟리간드 합성 및 평가
최선주,홍영돈,이소영,정성희 한국방사선산업학회 2015 방사선산업학회지 Vol.9 No.4
involved in the growth and spread of cancer cells to produce its cytotoxic effect. Either small molecule drugs or monoclonal antibodies are mostly used in targeted therapies. Unfortunately, targeted therapy has a certain degree of unwanted side effect like other cytotoxicityinducing chemotherapies. To overcome and to reduce unwanted side effects during a cancertherapy, recently radiopeptide therapies has got the worlds’ attraction for the tumor targetingmodalities due to its beneficial effect on less side effect compared to cytotoxic chemotherapies. Among radiopeptide therapies, 177Lu-DOTATATE is a major modality as an effective one inventedso far in treating neuroendocrine tumor (NET) and it has been in clinical trials at least one decade. Although it does have rather effective therapeutic effect on NET, it has less effective in ratherlarge solid tumor. There are many ways to improve or increase therapeutic effect of radiopeptideare a finding the potent small molecules to target the tumor site selectively, or a labeling withradioisotope of emitting high energy, or an improving its biological half-life by introducingdifferent moieties to increase lipophilicity. Present study was focus to increase a biological halflifeof radio somatostatin which will target the somatostatin receptor by altering the bifunctionalchelator (BFCA) by introducing lipophilic moiety to the somatostatin, which would make thelabeled peptide stay longer in the tumor site and thus it can intensify the therapeutic effect ontumor cell itself and around tissues.
오페라 공연 작품 실태조사를 통한 레퍼토리 확장에 관한 연구
최선주,조남규 한양대학교 우리춤연구소 2016 우리춤과 과학기술 Vol.12 No.3
본 연구는 지난 5년간 국내 5대 극장에서 공연된 오페라의 레퍼토리를 기초로 오페라 공연 현황을 분석하고, 그에 따른 레퍼토리의 확장에 관한 발전방안을 제언하는 데 그 목적을 둔다. 5대 극장별 공연 점유율 현황, 작품별 재연횟수, 관객 점유율 현황을 분석한 결과, 평균 공연 일수가 연간 24.9일(약 25일)로 나타났으며, 공연 횟수는 27.76회(약 28회)로 매우 낮은 수치를 보여주고 있었다. 반면 관객점유율은 74%로 높은 수치를 나타내었다. 5년간 재연된 작품을 분석한 결과, 첫째로 가장 많이 공연되고 선호하는 작품은 ‘베르디’, ‘푸치니’, ‘모차르트’ 등 작곡가의 레퍼토리였다. 둘째로 17회 공연된 ‘라트라비아타’와 16회 ‘라보엠’, 12회 ‘마술피리’, 10회 공연된 ‘카르멘’, ‘토스카’, ‘사랑의 묘약’을 제외한 나머지 작품들은 최근 5년간 10회 미만의 재연 숫자를 보여주었다. 연구결과 대체적으로 대중에게 익숙한 작품들이 객석점유율과 재연횟수가 높은 것을 알 수 있었다. 그러므로 작품개발을 통해 레퍼토리의 다양함과 시대의 변화에 따른 새로운 접근방법이 필요하다. 국내 오페라 공연의 전문성 확보와 대중적 활성화를 위한 국가적 투자와 오페라 단체의 노력이 절실히 필요하다. The aim of this research is to show how the genre and the themes of opera repertoires reflect their diversity and popularity by analyzing the opera performances based on the repertoires of operas which have been performed at five of the major theaters in Korea in the last five years. The share of the performances of each of the five theaters, the number of encores of each work, and the attendance of the audiences were analyzed. It shows relatively low figures of 24.9 performance days out of a year on average, for an average of 27.76 performances. Compared to the low number of performances, the audience attendance rate was high, at an average of 74 percent. The most frequently performed repertoires for the last 5 years were limited to those of Verdi, Puccini, and Mozart. Many works have been presented again less than 10 times in the last 5 years, except La Traviata which has been performed 17 times, La Boheme 16 times, The Magic Flute 12 times, Carmen, Tosca, and L’Elisir D’amore 10 times. According to data from the five major theaters, the works that the public are acquainted with more frequently have the higher percentage of attendance and the more frequent encores. We desperately need more diversity in the development of new opera repertoires and more accessibility to opera performances for the general public. Through the efforts of the opera community and national support, opera performances will be higher quality and more stimulating to audiences of all ages.
Hemorrhagic Rupture of Arachnoid Cyst into the Intradural Space
최선주,이희중,함명훈 대한자기공명의과학회 2017 Investigative Magnetic Resonance Imaging Vol.21 No.3
A 7-year-old boy, diagnosed with an arachnoid cyst and subdural effusion on initial MRI, was admitted with left limb weakness and no history of head trauma. A subsequent follow-up MRI showed different stages of hematoma within multilayered enhancing membranes and in the arachnoid cyst, which was separated by the cerebrospinal fluid cleft. Craniotomy and fenestration of the cyst wall and hematoma removal were performed. The patient was diagnosed as a having a hemorrhagic rupture of an arachnoid cyst into the intradural space, probably via some one-way valve-like defect, based on the MRI and surgical findings. The MRI features and possible mechanism of this rare disease are discussed within the literature review.