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      • 젊은 성인 남자의 흡연과 혈청 지질과의 관련성

        조선,류소연,박종,강명근,김은숙,김형철,박광희,윤혜은,노희송 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.2

        Objectives: This study was performed to find the association of cigarette smoking and blood lipid profiles in healthy young adults. Methods: The data was collected by a self-administered questionnaire and health examination in 489 professional soldiers from 6 to 12 May, 2004. The status of cigarette smoking was classified by non-smoking, ex-smoked, ≤4.9, 5-9.9, and ≥10 pack-years. The statistical analysis were used by chi-square test, analysis of variance and analysis of covariates. Results: In status of subjects cigarette smoking, current smoking, ex-smoked, and non-smoking were 71.8%, 11.2%, and 17.0%, respectively, In distribution by amount of smoking, non-smoking, ex-smoked, ≤4.9 pack-years, 5-9.9 pack-years, and ≥10 pack-years were 17.0%, 11.2%, 37.4%, 21.3%, and 13.1%, respectively. At other confounding variables were controlled, total cholesterol and LDL-cholesterol were increased significantly when amount of smoking was increased. However, triglyceride and HDL-cholesterol did not showed statistically significant differences, Conclusion: Smoking has relevant to total cholesterol and LDL-cholesterol and it is need to perform the further study for finding how blood lipid profiles are affected its level by cigarette smoking and to find an influence of cigarette smoking on cardiovascular disease.

      • KCI등재후보

        치과위생사의 감염관리 실태에 관한 연구

        조윤정,윤석준,안형식,김순덕,박형근 한국의료QA학회 2003 한국의료질향상학회지 Vol.10 No.2

        Background : Dental hygienists are at risk of acquiring infections through exposure to infectious agents. This study explores the frequency of exposure to infectious agents and infection control practices among dental hygienists. Methods : We undertook a cross-sectional survey to examine the exposure to infectious agents and infection control practices among dental hygienists through questionnaire. Data were obtained from 124 dental hygienists attending educational conferences. A multiple logistic regression analysis was conducted to determine the factors that effect infection control practices in to age, completion of infection control education, recognition of their own serum hepatitis Ag/Ab status, the number of one day patients, location of clinics, type of clinics, and career years. Results : Of the 124 dental hygienists, 91.7% were exposed to at least one accident such as needle strike injuries during their practices periods. The health screening coverage rate in dental hygienists was 16.5%. The number of one day patients and career years were important in relation to infection control practices among dental hygienists. The adjusted odds ratio estimates for career years were 5.049 times greater(95% CI 1.238-20.597)for groups with 4 career years than under 2 career years. That for the number of one day patients were 0.261(95% CI 0.071-0.0955)lower for through 20 up to 30 patients, 0.531(95% CI 0.102-2.78)lower for through 30 up to 40 patients and 0.498(95% CI 0.123-2.017)lower for more than 40 patients than under 20 patients. Conclusion : From these results, prevalence of infection control practices among dental hygienists is related to the number of one day patients and career years. Prevention of cross infection and reduction of future transmission should be a priority to dental hygienists for promotion of infection control and further efforts to educate newcomers on infection prevention should be made.

      • 서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

        김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

        Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

      • CIMT compared to Cardiac CT Ca score for estimating atherosclerosis in young fatty liver patient

        ( Incheol Yoon ),( Hyun-Jin Kim ),( Hyung-Bok Park ),( Yongsung Suh ),( Yoon-Hyeong Cho ),( Tae-Young Choi ),( Eui-Seok Hwang ),( Deok-Kyu Cho ) 대한내과학회 2015 대한내과학회 추계학술발표논문집 Vol.2015 No.1

        Background: As a surrogate of atherosclerosis, carotid intima-media thickness (IMT) and coronary artery calcium score (CACS) of over 100 by Cardiac CT scan can predict cardiovascular events. Fatty liver disease as a potential component of the metabolic syndrome is also linked to cardiovascular disease. This study evaluated the differences of the carotid IMT and the CACS in patients with fatty liver disease. Methods: The patients who had performed carotid, abdomen ultrasound and cardiac CT were evaluated retrospectively between Jun 2011 and December 2013. The primary outcome was the difference of the carotid IMT and the CACS between the fatty liver disease patients and patients with normal liver. Results: Among 819 patients (53.3 ±11.2 year), 330 patients had fatty liver disease. Patients with fatty liver disease had significant larger waist circumferences and body mass index. The incidences of hypertension, diabetes, and the dyslipidemia were also higher in patient with fatty liver disease. Furthermore, the carotid IMT was significantly thicker in patients with fatty liver disease than the patients with normal liver (0.79 ± 0.17 mm vs. 0.76 ±0.17 mm, p=0.012), and carotid plaque showed the more common tendency in patient with fatty liver disease (26.7% vs. 21.7%, p=0.099). The incidences of composite of the thick carotid IMT (≥75th percentile) and the plaque presence were significantly higher in fatty liver (43.0% vs. 36.0%, p=0.043). Especially patients under fifty years old, the carotid IMT was significantly thicker in patient with fatty liver than normal liver. Fatty liver disease increased the risk of the composite of the thick carotid IMT and the plaque in young patient (OR 1.83, 95% CI 1.00-3.34, p=0.05). However, the incidences of CACS of over 100 showed no significant difference between two groups. Conclusions: Carotid IMT reflect the worse baseline characteristics of the patients with fatty liver diseases than the CACS. Especially, fatty liver disease increase the risk of atherosclerosis in young patients under 50. Therefore, young patients with fatty liver disease need to perform screening IMT for detecting atherosclerosis and modifying the risk factors.

      • KCI등재

        Gender Difference of Cardiac Remodeling in University Athletes: Results from 2015 Gwangju Summer Universiade

        Hyun Ju Yoon,Kye Hun Kim,Kyle Hornsby,Jae Hyeong Park,Hyukjin Park,Hyung Yoon Kim,Jae Yeong Cho,Youngkeun Ahn,Myung Ho Jeong,Jeong Gwan Cho 대한심장학회 2021 Korean Circulation Journal Vol.51 No.5

        Background and Objectives: There is little data about cardiac geometry in highly trained young athletes, especially female specific changes. We investigated gender difference on exercise induced cardiac remodeling (EICR) in highly trained university athletes. Methods: A total of 1,185 university athletes divided into 2 groups; female (n=497, 22.0±2.3 years) vs. male (n=688, 22.6±2.4 years). Remodeling of the left ventricle (LV), left atrium (LA), right ventricle (RV), and any cardiac chamber were compared. Results: LV, LA, RV, and any remodeling was found in 156 (13.2%), 206 (17.4%), 82 (6.9%), and 379 athletes (31.9%), respectively. LV, LA, and any remodeling were more common in male than female athletes (n=53, 12.1% vs. n=103, 15.5%, p=0.065), (n=65, 13.1% vs. n=141, 20.5%, p<0.001), (n=144, 30.0% vs. n=235, 34.2%, p=0.058), respectively, whereas RV remodeling was significantly more common in female than male athletes (n=56, 11.3% vs. n=26, 3.8%, p<0.001). Interestingly, the development of LV, LA, and RV remodeling were not overlapped in many of athletes, suggesting different mechanism of EICR according to cardiac chamber. Various predictors including sports type, heart rate, muscle mass, fat mass, body surface area, and training time were differently involved in cardiac remodeling, and there were gender differences of these predictors for cardiac remodeling. Conclusions: EICR was common in both sex and was independently developed among cardiac chambers in highly trained university athletes. LV and LA remodeling were common in males, whereas RV remodeling was significantly more common in females demonstrating gender difference in EICR. The present study also demonstrated gender difference in the predictors of EICR.

      • SCIESCOPUSKCI등재
      • Carrier Lifetime Extension via the Incorporation of Robust Hole/Electron Blocking Layers in Bulk Heterojunction Polymer Solar Cells

        Yoon, Youngwoon,Kim, Hyeong Jun,Cho, Chul-Hee,Kim, Seulki,Son, Hae Jung,Ko, Min-Jae,Kim, Honggon,Lee, Doh-Kwon,Kim, Jin Young,Lee, Wonmok,Kim, Bumjoon J.,Kim, BongSoo American Chemical Society 2014 ACS APPLIED MATERIALS & INTERFACES Vol.6 No.1

        <P>We report the achievement of a power conversion efficiency (PCE) improvement in P3HT:PCBM-based bulk-heterojunction type polymer solar cells using photocrosslinked P3HT (c-P3HT) as the electron blocking/hole extraction layer and titanium oxide nanoparticles (TiO<SUB>2</SUB>) as the hole blocking/electron extraction layer. Devices prepared with a 20 nm thick c-P3HT layer showed an improved PCE of 3.4% compared to devices prepared without the c-P3HT layer (PCE = 3.0%). This improvement was attributed to an extension in the carrier lifetime and an enhancement in the carrier mobility. The incorporation of the c-P3HT layer lengthened (by more than a factor of 2) the carrier lifetime and increased (by a factor of 5) the hole mobility. These results suggest that the c-P3HT layer not only prevented non-geminate recombination but it also improved carrier transport. The PCE was further improved to 4.0% through the insertion of a TiO<SUB>2</SUB> layer that acted as an effective hole-blocking layer at the interface between the photoactive layer and the cathode. This work demonstrates that the incorporation of solution-processable hole and electron blocking/extraction layers offers an effective means for preventing nongeminate recombination at the interfaces between a photoactive layer and an electrode in bulk-heterojunction-type polymer solar cells.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/aamick/2014/aamick.2014.6.issue-1/am404381e/production/images/medium/am-2013-04381e_0008.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/am404381e'>ACS Electronic Supporting Info</A></P>

      • KCI등재

        Implementation of a resident night float system in a surgery department in Korea for 6 months: electronic medical record-based big data analysis and medical staff survey

        Hyeong Won Yu,June Young Choi,Young Suk Park,Hyung Sub Park,YoungRok Choi,Sang-Hoon Ahn,Eunyoung Kang,오흥권,Eun-Kyu Kim,Jai Young Cho,Duck-Woo Kim,Do Joong Park,Yoo-Seok Yoon,Sung Bum Kang,Hyung-Ho Kim 대한외과학회 2019 Annals of Surgical Treatment and Research(ASRT) Vol.96 No.5

        Purpose: To evaluate superiority of a night float (NF) system in comparison to a traditional night on-call (NO) system for surgical residents at a single institution in terms of efficacy, safety, and satisfaction. Methods: A NF system was implemented from March to September 2017 and big data analysis from electronic medical records was performed for all patients admitted for surgery or contacted from the emergency room (ER). Parameters including vital signs, mortality, and morbidity rates, as well as promptness of response to ER calls, were compared against a comparable period (March to September 2016) during which a NO system was in effect. A survey was also performed for physicians and nurses who had experienced both systems. Results: A total of 150,000 clinical data were analyzed. Under the NO and NF systems, a total of 3,900 and 3,726 patients were admitted for surgery. Mortality rates were similar but postoperative bleeding was significantly higher in the NO system (0.5% vs. 0.2%, P = 0.031). From the 1,462 and 1,354 patients under the NO and NF systems respectively, that required surgical consultation from the ER, the time to response was significantly shorter in the NF system (54.5 ± 70.7 minutes vs. 66.8 ± 83.8 minutes, P < 0.001). Both physicians (90.4%) and nurses (91.4%) agreed that the NF system was more beneficial. Conclusion: This is the first report of a NF system using big data analysis in Korea, and potential benefits of this new system were observed in both ward and ER patient management

      • On-chip concentration of bacteria using a 3D dielectrophoretic chip and subsequent laser-based DNA extraction in the same chip

        Cho, Yoon-Kyoung,Kim, Tae-hyeong,Lee, Jeong-Gun IOP 2010 JOURNAL OF MICROMECHANICS AND MICROENGINEERING - Vol.20 No.6

        <P>We report the on-chip concentration of bacteria using a dielectrophoretic (DEP) chip with 3D electrodes and subsequent laser-based DNA extraction in the same chip. The DEP chip has a set of interdigitated Au post electrodes with 50 µm height to generate a network of non-uniform electric fields for the efficient trapping by DEP. The metal post array was fabricated by photolithography and subsequent Ni and Au electroplating. Three model bacteria samples (<I>Escherichia coli</I>, <I>Staphylococcus epidermidis, Streptococcus mutans</I>) were tested and over 80-fold concentrations were achieved within 2 min. Subsequently, on-chip DNA extraction from the concentrated bacteria in the 3D DEP chip was performed by laser irradiation using the laser-irradiated magnetic bead system (LIMBS) in the same chip. The extracted DNA was analyzed with silicon chip-based real-time polymerase chain reaction (PCR). The total process of on-chip bacteria concentration and the subsequent DNA extraction can be completed within 10 min including the manual operation time.</P>

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