중환자에서 동맥혈 가스분석 횟수와 그로인한 실혈량에 대한 연구

이석열,전철우,정영수,오희숙,마분란,이정미,정혜영,이만복,이길노 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

Background : Arterial blood gas analysis is the most comon exam in intensive care unit. In this study, the frequency of blood gas analysis and the amount of blood loss after Blood Gas Analysis in Intensive Care Unit were observed. Methods : From November 1999 to February 2000, 115 patients admitted to intensive care unit at Soonchunhyang university Kumi hospital were studied prospectively for the frequency of blood gas analysis and the amount of blood loss after blood gas analysis in Intensive Care Unit. Results : The mean value of frequency of blood gas analysis was 6.41±6.49 and the mean value of amount of blood loss after blood gas analysis was 0.78ml. This was lower than that of other foreign reports. The patients with ventilator therapy above 24 hours showed higher frequency of blood gas analysis than that of not applied ventilator patients. Pulse oxymetry was applied to all patients and the frequency of blood gas analysis was decreased due to the use of strict pulse oxymetry. Conclusion : Doctors and nurses in intensive care unit keep in mind that adequate blood sampling is needed for the decrease of blood loss. Education and protocol for the decrease of blood loss after arterial blood gas analysis may be necessary.

노인의 영적 간호요구

최미혜,김경희,김귀옥,김기숙,김수강,김정신,김춘숙,노흥진,박지연,성혜연,오명선,이선희,이원옥,이윤영,이현수,장명재,차혜경,채정선,홍상희 중앙대학교 의과대학 간호학과 간호과학연구소 2001 중앙간호논문집 Vol.5 No.1

This study was designed to exam the aged's needs for spiritual nursing care. The purpose was to serve as a basis for the development of spiritual nursing practice. The major findings are as follows : 1. The degree of needs for spiritual nursing care as area was that needs of love and relationship mean 22.0, needs of meaning and object mean 28.2, needs of forgiving mean 13.5. Total needs for spiritual nursing care mean 63.7, which was on the upper middle level. The needs of meaning and object was rated highest. 2. Among the general characteristics of the subjects, needs of love and relatiohship wasn't significanlty different. 3. Among the general characteristics of the subjects, needs of meaning and object was significantly different according to two factors : age(F=7.260, p=0.001), religion(F=5.275, p=0.001). Higher needs of meaning and object was possessed by the older than the younger, by the one who have religion than the other. 4. Among the general characteristics of the subjects, four factors made a significantly difference to needs of forgiving : sex(t=-2.851, p=0.006), age(F=8.201, p=0.001), religion(F=6.928, p=0.000), disease(t=2.327, p=0.024). Higher needs of forgiving was possessed by man than woman, by the older than the younger, by the one who have religion than the other, by the one who have disease than the other.

New polymorphic microsatellite markers in the Korean mi-iuy croaker, $Miichthys$ $miiuy$, and their application to the genetic characterization of wild and farmed populations

An, Hye-Suck,Kim, Eun-Mi,Lee, Jang-Wook,Kim, Dae-Jung,Kim, Yi-Cheong The Korean Society for Integrative Biology 2012 Animal cells and systems Vol.16 No.1

Eighteen new polymorphic microsatellite markers were developed for the Korean mi-iuy croaker ($Miichthys$ $miiuy$, Perciformes, Sciaenidae), and allelic variability was compared between a wild population in Mokpo, Korea, and a hatchery population in Tongyeong, Korea. All loci were amplified readily and demonstrated allelic variability, with the number of alleles ranging from 5 to 37 in the wild population, and from 4 to 12 in the farmed population. The average observed and expected heterozygosities were estimated, respectively, to be 0.74 and 0.78 in the hatchery population samples, and 0.79 and 0.86 in the wild samples. These results indicate lower genetic variability in the hatchery population compared with the wild population, and significant genetic differentiation between the wild population and the hatchery samples ($F_{ST}$=0.058, P<0.001). These microsatellite loci may be valuable for future population genetic studies, monitoring changes in the genetic variation within stocks in a commercial breeding program, conservation genetics, and molecular assisted selective breeding of the mi-iuy croaker in the future.

한국비서자격시험의 개선점과 비교연구

남자현,이미정,이미영,이아영,정해금,최유정,이미숙,전인선,정혜림 이화여자대학교 법정대학 비서학과 1997 비서학연구 Vol.- No.17

일 도농복합지역 저소득층 노인의 건강문제 분석 : 보건소 방문간호사업 대상자 중심으로

고일선,,이태화,이경자,이정렬,임미혜,천의영,주윤미,이계철 노인간호학회 2005 노인간호학회지 Vol.7 No.2

Purpose: The purpose of this study was to analyze the health problems of low-income aged with chronic illness living in urban-rural composite area. Method: The sample consisted of 440 aged who were receiving home care services from a public health center. MDS-HC was applied to analyze the health problems of the aged. Data were collected through a face- to-face interview by six trained interviewers from June 28 to July 15, 2004. Result: Subjects had average number of 8 health problems in both urban and rural area. Lack of preventive health care measure, pain, and visual function were the most frequent health problem. The rural aged had more pain, bowel management problems, compared to the urban aged having more urinary incontinence and indwelling catheter. There were many health problems related to falls and pressure ulcers with middle-old aged in urban, and old-old aged in rural area. Conclusion: The results of this study showed strategies for care intervention of low-income elderly to put in practice. Therefore, tailored-service for each subject should be provided.

193 nm 용 화학 증폭형 감광제의 노광 후 열처리 과정 중 두께변화에 관한 연구

이은미,오혜근 한양대학교 이학기술연구소 2001 이학기술연구지 Vol.3 No.-

화학 증폭형 감광제의 중요한 특징 중 하나는 노광 후 열처리 과정에서 열처리 동안 화학적 반응이 증가하므로 열처리 조건에 따라 노광 된 영역의 감광제의 두께가 변한다는 사실이다. 그러나 지금까지는 이러한 사실을 무시한 채 시뮬레이션이 행해졌었다. 시뮬레이션에 있어서 좀더 정확한 결과를 얻기 위해서는 이러한 두께 감소 효과를 잘 표현해 줄 수 있는 더 나은 시뮬레이터가 필요하다. 본 논문에서는 노광 후 열처리 전후의 193 nm 용 화학 증폭형 감광제의 두께 변화를 측정하였으며 deprotected site의 농도 (Cas)와 두께 변화 사이의 관계를 추출해 내었다. 그리고 이를 자체 개발 시뮬레이터에 적용시켰으며 이것으로 더욱 실제와 가까운 감광제 프로파일을 얻을 수 있었다. 이 시뮬레이션은 탑 라운딩, 측면각, 초점 여유도, 노광량 감소 면에서 향상된 결과를 보여주었다. The chemical reaction is increased during post exposure bake and consequently the thickness of resist in the exposed area is physically reduced in most deep UV and 193 nm chemically amplified resists. However, the current simulator can only depict qualitative result without showing the desired quantitative result, so the demand for the simulator that can correctly mimic the real lithography process has been increased in recent years. In this study the thickness change of a 193 nm chemically amplified resist before and after post exposure bake was measured and the relationship JJetween the concentration of the deprotected sites and the thickness reduction was extracted. This resist thickness reduction effect was included in our modified simulator and more realistic resist profiles could be obtained. The simulation results showed enhancements in top rounding, sidewall angle, focus latitude and dose reduction.

소하천의 수질개선을 위한 자연정화공정 개발에 관한 연구

이혜미,오종민 경희대학교 환경연구소 2001 環境硏究 論文集 Vol.10 No.-

This study was performed to application of Porous concrete blocks and aquatic plants to water purification in small urban stream. This study was investigated the ability of water purification according to the variety of environment, epiphytic algae and aquatic plants. When the Porous concrete was used as contact media, the average removal efficiency of SS, BOD and COD were SS(85-95%), COD(50-60%), BOD(65-75%) respectively. Also when the Porous concrete and aquatic plants was used the average removal efficiency of SS and BOD were SS(90-95%), BOD(70-80%) respectively. In result, average removal efficiency of total nitrogen(T-N) with the Porous concrete and aquatic plants was about 40-50%. Average removal efficiency of total phosphorus(T-P) with the Porous concrete and aquatic plants was about 60-70%.

인터넷 브랜드 자산 구축 방안에 대한 연구

이종호,김문태,김미혜 釜山 大學校 經營 經濟 硏究所 2000 經營 經濟 硏究 Vol.19 No.1

21세기 초 경영의 화두는 전자상거래라고 할 수 있다. 학자들뿐만 아니라 많은 실무자들이 인터넷을 이용한 상거래에 많은 관심을 가지고 이에 대한 연구를 시작하고 있다. 전통적인 마케팅에서 각 제품의 성공 원동력과 실패의 원인은 모두 브랜드로 집약되고 있는데 이는 브랜드가 단순한 상표를 의미하는 것이 아닌 4P로 집약되는 다른 마케팅 도구보다 휠씬 더 기업의 성패에 큰 영향을 미칠 수 있는 효과적인 마케팅 도구이며 마케팅 자체를 나타내는 것이기 때문이다. 본 논문은 이러한 전통적인 브랜드 자산 구축전략을 토대로 인터넷 브랜드의 자산 구축전략은 어떻게 달라질 수 있는지 또 인터넷 자산구축 방안은 어떠한 것이 있는지 서술해 보고 이론적인 측면에서의 연구과제를 제시하는 것을 목적으로 한다.

여자고등학교 농구선수들의 학년별 식습관 차이 조사

이근일,김미선,임혜경 용인대학교 국제스포츠과학연구원 체육과학연구소 2008 體育科學硏究論叢 Vol.18 No.1

The purpose of this study is to investigate nutritional state and dietary behaviors in basketball athletes. Subject of this study was one hundred people of 23 female high school attending 1-2 grade. The measurement variable to investigate a nutritional state and dietary behaviors was main eating patterns, dietary behaviors, food intake and supplements. The result of analysis is as follows. 1. The difference of nutritional state as each grade was not a statistically difference among supplements and dinner, but there was a statistically difference among breakfast and lunch between groups. 2. Difference of intake lists was that one-grade were higher than two-grade intake from food, but two- grade were higher than one-grade in dairy product and fruit for additional taking nutrition. 3. The weight of intake food was that two-grade was statistically higher than one-grade in every lists. 4. The result of nutritive conditions each grade was that one-grade was statistically higher than one-grade. 5. The ingestion existence and nonexistence related to intake supplements of exercise nutrition was that two-grade was statistically higher than one-grade, intake frequency as well. Both one and two-grade response fatigue recovery and improving muscle in purpose of intake nutrition. and intake admonition was parents in two groups. above results from the study. We know nutrition intake frequency expect food is high as much as physical activity volume. we know high-nutrition intake is getting increase, as growing experience of exercise in case of one-grade.

시험관내 심내막염 모델에서 Methicillin 내성 포도구균에 대한 Vancomycin, Arbekacin, Gentamicin 단독 혹은 병합효과

이동건,전혜선,임동석,최수미,최정현,유진홍,신완식,강문원 대한감염학회 2003 감염과 화학요법 Vol.35 No.3

목적 : Methicillin 내성 포도구균(methicillin resistant Staphylococcus aureus, MRSA)은 병원감염의 중요한 원인균으로 vancomycin이 선택약제이다. 그러나 심내막염 등의 중증감염에서는 vancomycin의 치료실패와 함께 최근 내성균도 증가하고 있어 vancomycin을 대체할 수 있는 항균제와 보다 효과적인 항균요법의 개발이 필요하다. 본 연구에서는 사람의 환경과 유사한 시험관내 감염 모델을 적용하여 MRSA 치료를 위한 vancomycin, arbekacin, gentamicin의 단독 및 병합효과를 비교하였다. 방법 : 임상에서 분리된 MRSA 2균주(GRI 53, gentamicin 내성 : GS171, gentamicin 감수성)로 fibrin clot을 제작하여 시험관내 심내막염 모델을 만들어 vancomycin, arbekacin, gentamicin을 단독 혹은 병합주입하였다. 반감기와 최고 및 최저농도는 사람의 약동학을 기준으로 하였다. Vancomycin은 6, 12, 24시간마다 주입하거나 24시간 연속주입하였고 arbekacin은 12, 24시간마다, gentamicin은 8, 24시간마다 주입하였다. 병합주입의 경우 vancomycin은 12시간마다, gentamicin, arbekacin은 24시간마다 투여하였다. 각 투여군의 살균효과는 0, 8, 24, 32, 48, 72시간째의 fibrin clot내 집락수로 측정하였다. 결과 : GRI153에 gentamicin을 주입한 군 이외의 모든 실험군에서 대조군에 비해 의미있게 fibrin clot내 집락수가 감소하였다(P<0.001). Vancomycin과 arbekacin 단독주입군내서 8시간째의 집락수는 GRI153보다 GS171에서 의미있게 낮았고(P=0.02), GS171에 arbekacin 12시간마다 투여한 군의 집락수가 가장 낮았다(P=0.01). 72시간째 집락수는 균주의 종류나 vancomycin 혹은 arbekacin의 투여간격에 따른 차이가 없었다. GRI153에서 vancomycin과 arbekacin의 병합주입군은 24시간까지 상가작용이 있었으나 vancomycin과 gentamicin 병합주입에서는 무관작용이었고 GS171에서도 72시간 동안 무관작용을 보였다. 또한 전 실험기간 동안 내성균은 발현되지 않았다. 결론 : 시험관내 심내막염 모델에서 MRSA에 대한 arbekacin의 항균력은 vancomycin과 유사하여 단독주입이 가능함을 시사한다. Gentamicin 내성균주의 경우 두가지 항균제의 병합주입으로 24시간까지 상가작용을 보이고 있으나 임상에 적용하기 위해서는 추가연구가 필요할 것으로 생각된다. Background : Glycopeptide has been used for the one-and-only treatment of choice in methicillin resistant Staphylococcus aureus (MRSA) infection, but its exclusive use for the MRSA infection has led to the increased risk of glycopeptide-resistance. To find an alternative (s), we employed an in vitro infective endocarditis model (IVIEM) to compare the efficacy of vancomycin (VCM). arbekacin (ABK), and gentamicin (GM) alone or in combination. Methods : Using two strains of clinically isolated MRSA, one GM susceptible (GS171) and the other GM resistant (GR153), fibrin clots were prepared and suspended in IVIEM. Antibiotics were added as a bolus to simulate human pharmacokinetics of regimens, including q 6 h, q 12 h, q 24 h, or continuous infusion with VCM, q 12h or q 24 h with ABK, and q 8 h or q 24 h with GM. In cases of combination, regimens were VCM q 12 h plus ABK q 24 h, and VCM q 12 h plus GM q 24 h. Fibrin clots were removed from each model at 0, 8, 24, 32, 48. and 72 h, and the bacterial densities (in CFU/g) were determined. Results : At 8 hour, the colony counts of GS171 were lower than those of GR153 (P=0.02), and the lowest with the ABK q12h against GS171 (P=0.01). At 72 hour, monotherapy with ABK or VCM produced same degree of bacterial reductions in IVIEM, regardless of dosing frequency or GM-resistance. In the case of GM-resistance, combination of VCM and ABK did show additive effect until 24 hours, although VCM and GM showed no indifference during all the experiments. Development of resistance during experiment was not observed with any regimens. Conclusions : Our data suggest that ABK monotherapy could be used as an alternative to VCM even in the treatment of GM-resistant staphylococcal endocarditis. Further studies will clinical trials are warranted to evaluate the additive effect of VCM and ABK.