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서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)
김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2
Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.
NFC 기반 2 Factor 전자결제를 이용한 모바일 갤러리-옥션의 기능 검증 및 시현
차윤석(Yoon Seok Cha),오수희(Soo Hee Oh),김용일(YongIl Kim),노순국(SunKuk Noh) 한국스마트미디어학회 2018 스마트미디어저널 Vol.7 No.1
제노테크(주)는 NFC기반 2 factor 전자결제시스템의 보안기능 향상을 위해 FIDO인증기술을 이전받았으며 이를 활용하여 새로운 서비스인 갤러리-옥션을 개발하였고 대구 전시회에서 데모 시연을 진행하였다. 시연 결과 배너 제작 및 설치, UI변경, 동작 순서 변경 등의 개선 요구 사항이 있었으며 요구 사항을 바탕으로 갤러리-옥션을 개선하였다. 이후 개선된 갤러리-옥션의 2차 데모시연을 ‘아트:광주:17’에서 진행하였고 동시에 ‘아트:광주:17’의 시간당 입장객 수를 분석 및 시각화를 수행하였다. Acquisition of the FIDO authentication technology in pursuit of improved security function of the NFC-based 2 factor electronic payment system enabled GenoTech Ch., Ltd. to develop its new service, Gallery-Auction, demoed at Daegu Exhibition. The demonstration was followed by the improvement requests in banner creation & installation, changes in UI, changes in order of operation, etc, which were taken into account for the succeeding update. During the second demonstration held at Art: Gwangju: 17, it analyzed and visualized the number of visitors per hour there.
히트파이프 난방 시스템 controller 개발에 관한 연구
윤석암(Seok-Am Yoon),윤정필(Jeong-Phil Yoon),차인수(In-Su Cha),윤영찬(Yeong-Chan Yoon) 전력전자학회 2003 전력전자학술대회 논문집 Vol.2003 No.11
국내 난방 시스템은 대부분 화석에너지를 열원으로 하는 온수순환방식이다. 화석에너지를 사용하기 때문에 난방 시스템 가동에서 발생되는 공해는 대기 오염의 여러 원인 중 하나이며 가동 효율도 떨어진다.<br/> 이러한 단점들을 보완하기 위하여 새롭게 보급되고 있는 난방 시스템 중 히프파이프를 이용한 난방시스템은 전기에너지를 열원으로 사용하는 청정에너지로서 기존 난방시스템 보다 40%의 에너지 절감 효과를 나타내고 있다. 본 논문은 전기에너지를 사용하는 히팅 시스템의 제어를 위하여 개발된 컨트롤러에 관한 것이다.
Dong-Yoon Lim(Dong-Yoon Lim),Dong-Seok Cha(Dong-Seok Cha) 고려인삼학회 2002 Journal of Ginseng Research Vol.26 No.4
The present study was attempted to investigate the effects of total ginseng saponin (GTS), panaxadiol-type (PDS) and panaxatriol-type saponin (PTS) on contractile responses of vasoconstrictors in aortic smooth muscle stripes of normotensive (NR) and spontaneous hypertensive rats (SHR). Phenylephrine (an adrenergic α1-receptor agonist) and high potassium (a membrane depolarizing agent) caused greatly contractile responses in both NR and AHR aorta, respectively. Phenylephrine- and high potassium-induced contractile responses were greater in NA than those in SHR aortic smooth<br/> muscle stripes. In NR, the contractile responses of high potassium (5.6×10.2 M) were not affected in the presence of GTS (300 μg/ml), PDS (300 μg/ml), and PTS (300 μg/ml), respectively whereas phenylephrine (10.6 M)-induced contractile responses were markedly inhibited. In SHR, the contractile responses of high potassium (5.6×10.2 M) were not affected in the presence of GTS (300 μg/ml), PDS (300 μg/ml), and moderate doses of PTS (150-300 μg/ml), respectively but greatly blocked by high concentration of PTS (600 μg/ml). Phenylephrine (10.6 M)-induced contractile responses were<br/> inhibited in a dose dependent fashion (150-600 μg/ml) by the pretreatment with PTS while not altered in the presence of GTS (300 μg/ml) and PDS (300 μg/ml), respectively. Taken together, these experimental results suggest that ginseng saponins cause vascular relaxation through blockade of adrenergic α1-receptors and some unknown mechanisms, and that there is some difference in sensitivity of vascular smooth muscle between NR and SHR in responses to ginseng saponins. It seems that panaxatriol type of some ginseng saponins has the greatest potency in vascular relaxation.
방사선 조사가 파보바이러스 예방용 IgY를 함유하는 난황분말의 살균과 안정성에 미치는 영향
차인석(In-Seok Cha),박민근(Min-keun Park),이기정(Kie-Jeung Lee),윤세희(Sae-Hee Yoon),김정옥(Jeung-Ok Kim),김승희(Seung-Hee Kim),양재혁(Jae-Hyuk Yang),정종태(Jong-Tae Cheong),임윤규(Yoon-Kyu Lim),황규계(Kyu-Kye Hwang) 한국실험동물학회 2005 Laboratory Animal Research Vol.21 No.3
The gamma irradiation has been used as a method of sterilization which is often needed for long-term storage of various dried-foods by preventing them from decomposition. In present study, we tested the sterilization effects of gamma irradiation on the egg yolk powder containing anti-canine parvovirus yolk antibody (IgY) which can be used for controling canine parvovirus infection. Egg yolk powder was gamma irradiated at various levels (0.08, 0.4, 2, 10 and 50 kGy), stored at 4℃ and 20℃ for 60 days, and measured on sterility and antibody titer. Counting of aerobic bacteria indicated that samples irradiated at 0.4, 2 and 10 kGy were 89-94, 93-99 and 100% sterilized, respectively compared to non- irradiated control. ELISA test showed that gamma irradiation at 2 kGy or less did not make significant influence on antibody titer, whereas irradiation at 10 kGy induced about 15% reduction of antibody titer. Neither bacterial count nor antibody titer was affected by storage temperature after gamma irradiation. Conclusively, the proper level of gamma irradiation was about 2 kGy to achieve maximum sterilization on egg yolk powder without diminishing antibody titer.
Paste 법에 의한 STD61 강종의 Boronizing 처리에 관한 연구
윤재홍,남기석,차병묵,손명숙 대한금속재료학회(대한금속학회) 1996 대한금속·재료학회지 Vol.34 No.4
STD 61 steel was boronized in Boronizing paste mainly consisted of B₄C and Na₂B₄O_7 at various temperatures and times. Microhardness and thickness of boride layers were measured and distributions of B, Si, Cr, and V on the cross section of specimens were observed by EPMA line analysis. Microscopic examination and results of EPMA showed that the boride layer consisted of two layers outer layer of FeB and inner layer of Fe₂B. Microhardness of these boride layers was in the range of Hv 1800∼2300. Thickness of the boride layer increased with a square root of time for treatment at constant temperature. Activation energy for diffusion of B in the specimen obtained from the slope of Arrhenius plots was 260kJ/㏖. Si-rich α layer was formed between boride layer and matrix. Element such as Cr concentrated as Cr_(23)(B, C)_6 beneath the boride layer.
성장기 흰쥐에서 단백질 장기간 알코올 투여가 인슐린 분비능 및 감수성에 미치는 영향
윤용석,허갑범,이현철,임승길,김경래,송영득,안철우,차봉수,이해일,성제경 대한당뇨병학회 2000 Diabetes and Metabolism Journal Vol.24 No.1
Background: This investigation was performed to examine the combined effects of protein malnutrition and chronic moderate amount of alcohol intake on insulin secretory capacity and sensitivity in growing rats. Methods: Weanling 4-week-old male Sprague-Dawley rats were fed low protein [5%, (wt/wt)] or control (C, 20%) diet from 4 to 12 weeks and alcohol (5 g/kg/d) or saline gavage from 8 to 12 weeks. All rats were divided into the 4 groups according to different diet protocols: group I (protein-deficient alcohol rats), group II (protein-deficient saline rats), group III (protein-sufficient alcohol rats), and group IV (protein-sufficient saline or control rats). At the age of 12 weeks, we determined the insulin secretory capacity and sensitivity in the 4 different diet groups. Results: The results are summarized as following; 1. Normal weight gain was nearly completely arrested in protein-deficient rats compared to control rats. In protein-sufficient rats, chronic alcohol intake decreased body weight gain. Pancreatic weight adjusted with body weight was not different among the 4 groups, but epididymal fat weight adjusted with body weight was decreased in group II compared to group IV. 2. Intraperitoneal glucose tolerance was improved in group I compared to the other groups. Insulin responses to glucose challenge were markedly decreased in group II compared to group IV, but not in group I. 3. Glucose disposal rate during euglycemic clamp test was diminished in group II compared to group IV, but there were no differences between group I and group IV. Glycogen synthase activities of skeletal muscle after 2 hour hyperinsulinemic state were not different among the 4 groups. 4. There were no differences of reserved insulin content of whole pancreas adjusted with pancreas weight among the 4 groups. 5. In light microscopic findings of pancreatic islets, sizes of islets, islet cells and nuclei were decreased in protein-deficient rats compared to control rats. However, the sizes of islet cells and nuclei were further decreased in group II compared to group I. Conclusion: These results suggest that impaired insulin secretion and decreased insulin sensitivity due to protein malnutrition can be restored by chronic, moderate amount of alcohol intake, but these beneficial effects may not be appeared in protein-sufficient state. Therefore, the chronic alcohol intake differently influences glucose metabolism according to individual nutritional status, and further studies for the effects of alcohol intake in lean diabetic patients are required to extrapolate these results in human.