CdSe ; Cu 광전도 cell 제작

신영진,정태수,신현길,김택성,정철훈,이훈,신영신 경북대학교 센서기술연구소 1992 센서技術學術大會論文集 Vol.3 No.1

요부수핵탈출증에서 Thermography의 진단적 가치

신현택,신승우,송재철,정석희,이종수,김성수,신현대 경희대학교 동서의학연구소 2001 東西醫學硏究所 論文集 Vol.2000 No.-

Objectives : Lumbar radiculopathy is a common disease in oriental rehabilitation medicine. It can be diagnosed by physical examination, plain X-ray, Myelography, CT, MRI, EMG etc. But those methods are not useful in observing the clinical procedure. Objectvie evaluating the clinical procedure is very important in treatment of lumbar radiculopathy. Mehthods : We studied the clinical efficacy of thermography in lumbar radiculopathy during conservative managements. We studied 36 patients with lumbar radiculopathy convinced by MRI. The had low back pain and radiating pain on one side. Thermography had taken before an after 4 weeks treatments, and compared with clinical procedure Results and conclusions : Thermography is not pertinent as a primary diagnostic method in lumbar radiculopathy, but useful in observing the clinical procedure. And it can be recommended as a objective evaluation for lumbar radiculopathy.

Photonic Crystals: Integration of Colloidal Photonic Crystals toward Miniaturized Spectrometers (Adv. Mater. 9/2010)

Kim, Shin-Hyun,Park, Hyo Sung,Choi, Jae Hoon,Shim, Jae Won,Yang, Seung-Man WILEY-VCH Verlag 2010 Advanced materials Vol.22 No.9

<B>Graphic Abstract</B> <P>The cover shows a schematic illustration of patterned colloidal photonic crystals with different bandgap positions. When an unknown light source impinges on the patterned photonic crystals, the light information can be identified from the reflection intensity profile of the constituent photonic crystals. The two optical microscopy images and background image display integrated photonic crystals with 20 different bandgaps spanning the entire visible range, and the SEM image shows the cross-section of the photonic crystal stripes, as reported by Shin-Hyun Kim, Seung-Man Yang, and co-workers on p. 946. <img src='wiley_img_2010/09359648-2010-22-9-ADMA201090022-content.gif' alt='wiley_img_2010/09359648-2010-22-9-ADMA201090022-content'> </P>

傷寒論에 대한 精神醫學的 硏究

文相泰,辛容玹,具炳壽 대한한방신경정신과학회 2000 동의신경정신과학회지 Vol.11 No.1

This study was aimed to get the course which is caused by Neuropsychiatric symptoms in Sang-Han. Therefore this study is based on 『Euhak-Ipmun. Sang-Han』(『醫學入門.傷寒』) classfied mainly by symptoms. The results were summerized as follows: 1. Neuropsychiatric symptoms in 『Euhak-Ipmun. Sang-Han』(『醫學入門. 傷寒』) are explained as Pal-Gang(八綱), which shows those are settled down to a systematic oriental medical theory. 2. Pal-Bup (八法) used in the cure of symptomatische psychose in 『Euhak-Ipmun. Sang-Han』(『醫學入門. 傷寒』), which is intended to boost the effect of cure, choosing the respondent cure method about various causes. 3. Pal-Gang(八綱) and Pal-Bup(八法) in『Euhak-Ipmun. Sang-Han』(『醫學入門·傷寒』) are improved by Lee-Chun(李 ) who added Jang-gi(張機)'s Sang Han theory and new medical thought in the ages of Geum. Won. 4. Lee-Chun(李 ) believed that Neuropsychiatric symptoms which appeared in Sang Hang is caused by the "Unbalance(不平)". So he wanted to reach harmony of "Jeong(精), QI(氣), Shin(神), Hyul(血)" after improving the status of "Unbalance(『不平』)" toward the status of "Balance(平)".

한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고

양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

녹동균 세포외막 단백질 백신 CFC-1-101의 안정성 및 면역원성 검토 : 임상 제 Ⅰ/Ⅱa상 시험

장인진,김익상,유경상,임동석,김형기,신상구,장우현,박완제,이나경,정상보,안동호,조양제,안보영,이윤하,김영지,남성우,김현수 대한감염학회 1998 감염 Vol.30 No.3

목적 : 제일제당에서는 녹농균의 세포외막 단밸질을 유효성분으로 하는 백신인 CFC-101을 개발하였으며, 동물시험에서 이 백신의 안전성과 유효성을 입증하였다. 본 연구에서는 이 녹농균 백신의 인체에 대한 안전성과 면역원성을 평가하는 동시에 인체 접종시의 최적 투여 용량을 결정하기 위하여 제 I/Ⅱa상 임상시험을 수행하였다. 방법 : 건강한 성인 남자를 피험자로 선별하여 각 용량군에 백신투여자 6명, 위약투여자 2명을 배정하였다. 백신 투여군은 0.25mg, 0.5mg 또는 1.0mg 용량의 녹농균 백신을 7일 간격으로 3회에 걸쳐 근육주사 하였으며, 위약 투여군에게는 세포외막 단백질을 제외한 동일한 성분을 투여하였다. 백신접종 후 국소적 또는 전신적인 반응의 발생여부를 관찰하고, 혈액시료를 체취하여 백신의 역가와 유효성을 검정하였다. 결과 : 녹농균 백신 CFC-101은 모든 접종자에서 양호한 내약성을 보였다. 또한 0.5mg 과 1.0mg 백신 투여군에서는 100%의 항체양전율을 나타내었다. 생성된 항체는 녹농균 세포외막단백질에 특이성을 보였고, 녹농균 감염에 대해 방어효능이 있었다. 결론 : 이와같은 결과로부터 이 녹농균 백신은 인체에 안전하게 투여할 수 있으며, 높은 항체 생성능으로 감염방어 효능을 보이고 0.5mg과 1.0mg이 최적용량인 것으로 판단되었다. Background : We developed a Pseudomonas aeruginosa outer membrane protein(OMP) vaccine CFC-101, and the prophylactic efficacy of which has been demonstrated in animal models. In order to evaluate the safety and immunogenicity of the P. aeruginosa vaccine, we carried out a phase I/Ⅱa clinical trial in healthy male volunteers. Methods : Groups of eight volunteers, including two placebo subjects, were vaccinated intramuscularly with three doses of 0.25, 0.5 or 1.0 mg of the vaccine at one week intervals. Sings of systemic and local reactions observed after vaccination were recorded for each vaccinee for 5 days. Physical examinations were performed on days 0, 1, 7, 8, 14, 15, 21, and 42, and clinical laboratory tests were done on days 0, 3, and 21. Blood samples for assay of serum antibody levels were obtained up to 42 days after the first vaccination. Results : The vaccine was generally well tolerated by all vaccinees, showing no significant side effects. In the three dosage groups, all vaccinees, except one receiving the 0.25 mg dose, showed significant elevation in serum IgG antibody titers against the vaccine proteins, indicating 100% seroconversion in 0.5 and 1.0 mg groups. The human antibodies induced by the vaccine were specific for P. aeruginosa OMPs, as confirmed by western blot analysis and immunoprecipitation assays. The capacity of the human antisera to enhance opsonophagocytic killing activity by polymorphonuclear leukocytes and to confer protection against P. aeruginosa infections indicates that the antibodies elicited by the vaccine have protective efficacy. Conclusion : We conclude that the P. aeruginosa OMP vaccine is safe and effective for human use and its optimal dose to be 0.5 or 1.0 mg.

대나무 섬유소를 이용한 섬유보강 콘크리트의 역학적 특성

류현기,권용주,신상용 忠州大學校 2009 한국교통대학교 논문집 Vol.44 No.-

This study is a experiment on the mechanical properties of concrete according to the fiber additional quantity of bamboo. The experiment and analysis results are as the following. The slump as a quality of the concrete not to harden showed to decrease more remarkably for a slump value than the plain according to the increment of cellulose additional rate. Air quantity showed to increase only in 0.2% fiber additional rate and to get out of KS allowable error of bad air content in 0.4% and 0.6%, and capacity mass by unit showed a reverse tendency against air quantity according to the change of cellulose additional quantity. Compression intensity as a quality of hardening concrete showed collectively a tendency to decrease in the remnant past days except only 0.6% at the standard past day 愀8 and the initial 3 days. Pulling intensity showed to increase more than the plain in all past days according to the change of fiber additional quantity of bamboo, and bending intensity also showed to be higher revelation intensity than the plain in the measurement result at the standard past day 28. In the result of length change rate, we can find the bigger the cellulose additional rate as a special quality increased, the more it decreased according to the pass of the past day.

수학적 모델링을 통한 교육과정의 구성원리

신현성 한국학교수학회 2001 韓國學校數學會論文集 Vol.4 No.2

The paper describes some principles how we design the mathematics curriculum through mathematical Modelling since the motivation for modelling is that it give us a cheap and rapid method of answering illposed problem concerning the real world situations. The experiment was focussed on the possibility that they can involved in modelling problem sets and carry modelling process. The main principles could be described as follows. principle 1. we as a teacher should introduce the modelling problems which have many constraints at the begining situation, but later eliminate those constraints possibly. principle 2. we should avoid the modelling real situations which contain the huge data collection ion the classroom, but those could be involved in the mathematics club and job oriented problem solving. principle 3. Analysis of modelling situations should be much emphasized in those process of mathematics curriculum. principle 4. As a matter of decision, the teachers should have their own activities that do mathematics curriculum free. principle 5. New strategies appropriate in solving modelling problem could be developed, so that these could contain those of polya's heusistics

筋骨格系 領域에서 Thermography의 臨床的 活用에 對한 考察

신현택,정석희,이종수,김성수,신현대 경희대학교 동서의학연구소 2001 東西醫學硏究所 論文集 Vol.2000 No.-

근골격계 질환은 임상에서 가장 흔하게 접할 수 있는 대상의 하나로 그 진단과 평가가 매우 중요하며 여러 가지 진단기기와 평가방법이 이용되고 있다. Thermography는 기존의 진단기기와 달리 질병의 기능적인 측면을 평가할 수 있다는 점과 통증과 같은 주관적인 표현을 어느정도 객관화할 수 있다는 점에서 임상적 가치가 고려되고 있다. 본 연구는 최근 국내외의 임상 논문을 대상으로 근골격계 영역에서 Thermography의 활용 동향을 고찰하여 진단적 가치를 확인하고자 하였다. Thermography는 척추신경병증, 근막동통증후군, 말초신경병증, 반사성 교감신경 이영양증, 레이노증후군, 악관절 장애 및 일부 기타 질환에서 적용되었으며, 대부분의 질환에서 보조적인 진단기기로 활용가치가 있었다. 특히, 질병의 경과 관찰과 약물 및 기타 처치에 대한 효과 판정에 유용하였으며, 레이노 증후군 및 반사성 교감신경 이영양증과 같은 질병에서는 일차적인 진단기기로도 활용이 가능하였다. 향후 근골격계 영역에서 Thermography의 보다 폭넓은 적용을 위해서는 질환에 따른 적절한 촬영방법의 개발 및 결과 판독에 대한 객관성 확보가 있어야 할 것이다. The purpose of this study is to assess the usefulness of thermography in patients with musculoskeletal disease. Thermography is noninvasive, easy to reading, objective and physiologic instrument by measuring and imaging infrared energy emitted from skin surface. Thermography can show the skin temperature changes in various conditions of the body with musculoskeletal disease. This literature review was done for the usefulness of thermography in diagnosing musculoskeletal disease. In conclusion, thermography was adapted in radiculopathy, MPS, peripheral neuropathy, RSD, Raynaud's phenomen, TMJ dysfunction, etc. It was useful as a secondary diagnostic method in those diseases, also possible as a primary diagnostic method in RSD, Raynaud's phenomen. And, it might be reliable tool for estimating disease procedure and consequence after treatment. But, the objectivity of the reading and the development of the operating method are required for further adaptation in musculoskeletal disease.

Effect of Platelet-Rich Fibrin on Repair of Defect in the Articular Disc in Rabbit Temporomandibular Joint by Platelet-Rich Fibrin

( Hyun Su Baek ),( Hye Sung Lee ),( Bok Joo Kim ),( In Kyo Chung ),( Chul Hoon Kim ),( Sun Mi Jin ),( Hie Sung Hwang ),( Sang Hun Shin2 ) 한국조직공학·재생의학회 2011 조직공학과 재생의학 Vol.8 No.6

The objective of this study was to evaluate platelet-rich fibrin (PRF)’s effectiveness in repairing articular disc defect in the temporomandibular joint (TMJ) of rabbits. Eight rabbits were divided into four groups of two rabbits each, corresponding to groups A, B, C, and D. Both TMJs of all of the rabbits were used in the experiments: the right joints comprised the experimental groups, and the left ones, the control groups. The disc defect was circular and 2 mm in diameter. In the experimental groups, the PRF was compressed into the defect, whereas the control group defects were left untreated. A, B, C, and D groups were sacrificed at the 1st, 2nd, 4th and 6th weeks, respectively. The defects of each control group exhibited no specific changes. Contrastingly, in each experimental group, there was an increased number of chondroblasts at the margins of the defects, along with accelerated cell differentiation and a columnar cell arrangement observable at the time of cell differentiation. The experimental groups showed inflammatory cell infiltrations and fibrosis by the 1st week, maturation of chondrocytes by the 2nd week, and proliferation by the 4th week, after which the defects began to be filled with chondrocytes, a process that was complete after the 6th week. In the histological evaluation (H-E), the experimental groups showed significant increases of chondroblasts after the 2nd and 4th weeks, as well as regular columns of chondrocyte arrays observable during cell division. After 6 weeks, the defects were filled with chondrocytes.