『방약합편(方藥合編)』에 수재된 신경정신과(神經精神科) 관련 주요 처방(處方)에 대한 연구(硏究)

김지훈 ( Jee Hoon Kim ),구병수 ( Byung Soo Koo ),김근우 ( Geun Woo Kim ) 대한한방신경정신과학회 2009 동의신경정신과학회지 Vol.20 No.1

Objectives: The purpose of this study is to analysis of the herb medications corresponded with neuropsychiatry of 『Bang-Yak-Hap-Pyun』. Methods: The herb medications of 『Bang-Yak-Hap-Pyun』Sang·Jung·Ha-Tong(上·中·下統) and 『Enlargement side prescriptions』(增補方) are selected by comment on the chief virtue including reference word of corresponded with neuropsychiatry. Results and Conclusion: 『Bang-Yak-Hap-Pyun』is a book most people who have a background or career in Han Medicine(韓醫學) would pore over. They corresponded with neuropsychiatry among the herb medications of 『Bang-Yak-Hap-Pyun』Sang·Jung·Ha-Tong(上·中·下統) are 55 prescriptions that Sang-Tong(上統) is 8 prescriptions, Jung-Tong(中統) is 23 prescriptions and Ha-Tong(下統) is 24 prescriptions. And the herb medications corresponded with neuropsychiatry of 『Enlargement side prescriptions』(增補方) are 40 prescriptions. And then the herb medications corresponded with neuropsychiatry of 『Bang-Yak-Hap-Pyun』received much influence from 『Dong-Eui-Bo-Gam』. Incidentally the herb medications corresponded with neuropsychiatry of 『Bang-Yak-Hap-Pyun』Sang·Jung·Ha-Tong showed the high percentage in Neurosis. And the herb medications corresponded with neuropsychiatry of 『Enlargement side prescriptions』showed the high percentage in Psychosis. Besides not only put 『Enlargement side prescriptions』a premium on 『Dong-Eui-Bo-Gam』, but also made it the herb medications which were recorded on books flowed after 『Dong-Eui-Bo-Gam』known. It was entered up books quoted from『Bang-Yak-Hap-Pyun』Sang·Jung·Ha-Tong but the herb medications were that were not succeeded from 『Bang-Yak-Hap-Pyun』Sang·Jung·Ha-Tong. Therefore 『Enlargement side prescriptions』 shows the efforts for supplement of 『Bang-Yak-Hap-Pyun』Sang·Jung·Ha-Tong.

트리메틸틴에 의해 유도된 흰쥐의 학습과 기억력 손상에 대한 육미지황탕가미방의 신경보호 효과

정희상 ( Hee Sang Jeung ),김근우 ( Geun Woo Kim ),구병수 ( Byung Soo Koo ) 대한한방신경정신과학회 2009 동의신경정신과학회지 Vol.20 No.1

목적: 이 연구는 알쯔하이머 병에 대한 육미지황가미방의 효과를 조사하였다. 육미지황가미방은 산약, 산수유, 복령, 목단피, 구기자, 택사, 숙지황을 포함한 여러 가지 한약재의 전탕액으로 치매의 한약 치료제로 널리 사용되어 왔다. 방법: 이 약물의 신경보호 작용을 조사하기 위해, 수중미로를 사용하여 학습과 기억에 대한 육미지황가미방의 효과를 평가했고, 트리메틸틴으로 신경과 인지 장애를 유발시킨 쥐의 해마의 중추성 콜린계에서의 작용을 연구했다. 트리메틸틴은 강력한 유독물질로 선택적으로 중추신경계와 면역계의 세포를 파괴시킨다. 트리메틸틴(6.0 mg/kg, i.p.) 주입 후, 쥐에게 육미지황가미방(400 mg/kg, p.o.)를 2주 동안 날마다 복용시켰으며, 수중미로를 수행시켰다. 결과: 육미지황가미방을 트리메틸틴에 노출시킨 쥐에 투약했으며, 그들은 수중미로에서 학습과 기억의 향상을 보였고, 이는 육미지황가미방이 어떠한 환경에서는 트리메틸틴으로 유발된 신경퇴화 후 중추신경계의 결손을 감소시킬 수 있음을 보여준다. 결론: 이러한 결론은 육미지황가미방이 인지능력을 증가시키고, 트리메틸틴으로 유발된 신경퇴화에서 콜린 아세틸전환효소의 정도를 변화시킬 수 있음을 보여준다.

神經精神科 疾患과 關聯된 醫案의 硏究 : 中國 宋ㆍ金ㆍ元ㆍ明 時代 醫案을 中心으로

權保亨,具炳壽 대한한방신경정신과학회 1997 동의신경정신과학회지 Vol.8 No.1

according to study of clinical document in relation to Neuropsychiatric disease in Ancient Chinese(Song, Keum, Won, Myung) clinical document the result were obtained as follows. 1. A main point is Jeul-Jin<切診> in diagnosis, that is Hyun-Maeg<弦脈> is liver disease, Whual Mag<滑脈> is gallbladder disease, Sag Mag<數脈> is fever. 2. Doctors in Song<宋>, Keum<金>,Won<元> enumerationed many diseases are cause by emotion. 3. Oriental psychotherapy that Diseases caused by surprising must be cure by surprising is like to systematic desensitization in Westem. 4. Oriental psychotherapy that pseudopsychosis must be cure by patient rely on doctor is like to suggestive therapy in western. 5. It is similar to suggestive therapy in western medicine that Sadness ,anguish and frustration induce disease. 6. Headache is caused by fever, energy deficience and angry. 7. Imsomnia is not caused by hsart disease, but gallbladder or liver. 8. Schizophrenia is caused by shocking and a sort of fever. 9. Epilepsy is caused by a sort of fever, shocking and fetal disease. 10 Schizophrenia(in case of manic state) is caused by fever and shocking, and imaginary pregnancy is considered as schizophrenia.

神經精神科 疾患과 聯關된 醫案의 硏究 (Ⅱ) : 中國 淸 時代 醫案을 中心으로

權保亨,具炳壽 대한한방신경정신과학회 1998 동의신경정신과학회지 Vol.9 No.2

한방병원 응급실에 내원한 신경정신과 환자의 임상고찰 및 SCL-90-R에 의한 특성

최보윤 ( Bo Yun Choi ),박지운 ( Ji Un Park ),정인철 ( In Chul Jung ),이상룡 ( Sang Ryong Lee ) 대한한방신경정신과학회 2003 동의신경정신과학회지 Vol.14 No.2

가미보양환오탕(加味補陽還五湯) 열수추출물, 초미세분말제형이 Alzheimer`s Disease 병태 모델에 미치는 영향

서승호 ( Seung Ho Seo ),정인철 ( In Chul Jung ),이상룡 ( Sang Ryong Lee ) 대한한방신경정신과학회 2008 동의신경정신과학회지 Vol.19 No.3

Objective : This experiment was designed to investigate the effects of the KBHT hot water extract & ultra-fine powder on Alzheimer`s Disease Model Induced by βA. Method : The effects of the KBHT hot water extract on expression of proinflammatory cytokine mRNA in BV2 microglial celll cell line treated by lipopolysacchaide(LPS). The effects of the KBHT hot water extract & ultra-fine powder on (1) the behavior (2) AChE in serum (3) the infarction area of the hippocampus, and brain tissue injury in Alzheimer`s diseased mice induced with βA were investigated. Results : 1. The KBHT hot water extract suppressed the expression of proinflammatory cytokine mRNA in BV2 microglial cell line treated with LPS. 2. The KBHT hot water extract & ultra-fine powder a significant inhibitory effect on the memory deficit was shown for the mice with Alzheimer`s disease induced by βA in the Morris water maze experiment, which measured stop-through latency and distance movemet-through latency 3. The KBHT hot water extract & ultra-fine powder suppressed the over-expression of AChE activity in the serum of the mice with Alzheimer`s disease induced by βA. 4. The KBHT hot water extract & ultra-fine powder suppressed the expression of TNF-α, IL-1β protein significantly in the microglial cell of mice with Alzheimer`s disease induced by βA. 5. The KBHT ultra-fine powder reduced infarction area of hippocampus significantly in the mice with Alzheimer`s disease induced by βA. Conclusions : These results suggest that the KBHT hot water extract & ultra-fine powder may be effective for the prevention and treatment of Alzheimer`s disease. Investigation into the clinical use of the PMCMT hot water extract & ultra-fine powder for Alzheimer`s disease is suggested for future research.

우울, 불안, 불면 환자에 대한 심리척도의 유용성과 상관성에 대한 임상연구

박대명 ( Dae Myung Park ),이상룡 ( Sang Ryong Lee ),정인철 ( In Chul Jung ) 대한한방신경정신과학회 2012 동의신경정신과학회지 Vol.23 No.3

Objectives : The aim of this study was to investigate the value and efficacy of BDI, STAI, STAXI, ISI, and SCL-90-R in correlation with depression, anxiety, and insomnia patients. Methods : A total of 39 patients, who were diagnosed with depression, anxiety, and insomnia were evaluated using BDI, STAI, STAXI, ISI, and SCL-90-R. They were then statistically analyzed. Results : 1. BDI scores of depression patients were significantly different from other patients. 2. BDI scores of depression patients had strong positive correlation with STAI-S, and STAI-T scores. 3. STAI-S scores of anxiety patients had positive correlation with BDI, and ISI scores. 4. SCL-90-R depression subscale scores of depression patients had strong positive correlation with somatization, obsessive compulsive, interpersonal sensitivity, anxiety, hostility, phobic anxiety, paranoid ideation, psychoticism, global severity index, and positive symptom total subscale scores. 5. SCL-90-R anxiety subscale scores of anxiety patients had strong positive correlation with somatization, obsessive compulsive, depression, phobic anxiety, and global severity index subscale scores. Phobic anxiety subscale scores had strong positive correlation with anxiety, global severity index, and positive symptom total subscale scores. Conclusions : The result findings are expected to serve as a useful resource in future stress-related depression, anxiety, and insomnia case reports and clinical research in oriental neuropsychiatry.

대사증후군이 동반된 간화상염 변증 환자에 대한 한의정신요법 병행 한의치료 증례보고

조준희,임정화,김보경 대한한방신경정신과학회 2022 동의신경정신과학회지 Vol.33 No.4

The purpose of this study is to report a case of a patient with pattern identification of liver fire flaming upward and metabolic syndrome improved by Korean medicine. The patient felt completely lost. She was treated for headache, insomnia, and metabolic syndrome with Korean medicine and psychotherapy. Pittsburgh Sleep Quality Index (PSQI), Insomnia Severity Index (ISI), Pattern Identification Tool for Insomnia (PIT-Insomnia), Minnesota multiphasic personality inventory-2 (MMPI-2), and bioelectrical impedance analysis (BIA) were used for assessment. During treatment for six months, the patient stopped taking headache pills. Her blood pressure was stabilized. Her body weight, body fat, body mass index (BMI), and visceral fat decreased significantly. The sum of ISI, PSQI, PIT-insomnia also decreased significantly. Her Ego strength increased in the MMPI-2 supplementary scale. We assume that Korean medicine treatment through acupuncture, herbal medicine, and psychotherapy is effective in treating pattern identification of liver fire flaming upward and metabolic syndrome.

한방병원에 근무하는 간호사의 정신건강에 대한 연구동향: 국내연구를 중심으로

권찬영 ( Chan-young Kwon ),박정현 ( Jung Hyeon Park ),하다정 ( Da-jung Ha ) 대한한방신경정신과학회 2021 동의신경정신과학회지 Vol.32 No.1

Objectives: The aim of this scoping review was to analyze research trends about mental health of nurses working in Korean medicine (KM) hospitals in Republic of Korea. Methods: Searches were conducted using four electronic databases including Oriental Medicine Advanced Searching Integrated System, Korean Studies Information Service System, Research Information Sharing Service, Korea Citation Index to collect relevant studies. The search date was March 4, 2021. All studies published up to the search date were considered. Observational studies reporting mental health outcomes of nurses working at KM Hospital were included. Results: A total of 11 cross-sectional observation studies were included. Four of them compared mental health of nurses working on KM and Western medicine (WM). Commonly reported outcomes related to mental health were job satisfaction, role conflict, and work stress. As a result of meta-analysis based on a 5-point Likert scale, the following factors were related to mental health of KM nurses: job satisfaction (2.844±0.067 points), role conflict (3.678±0.058 points), work stress (3.142±0.021 points), turnover intention (3.483±0.028 points), and burnout (3.180±0.033). Compared to WM nurses, KM nurses had significantly less work stress (p=0.000), role conflict (p=0.039), and job satisfaction (p=0.000). Conclusions: Mental health problems of nurses are known to be very common. Although improving them is an important social task, studies on mental health of KM nurses remain insufficient. Based on findings of this study, more cooperation between nurses and KM doctors should be made to improve the mental health of KM nurses, especially their job satisfaction in the future. The Korean Society of Oriental Neuropsychiatry needs to pay more attention to this topic.

문무잡과(文武雜科) 방목(榜目)의 의사학적(醫史學的) 가치(價値)

유희영 대한한방신경정신과학회 1990 동의신경정신과학회지 Vol.1 No.1