만성중이염의 골도청력변화

박선홍,노용훈,이도용,나한조,김용기,최봉남,도남용 朝鮮大學校 附設 醫學硏究所 1996 The Medical Journal of Chosun University Vol.21 No.1

We have usually experienced bone conduction impairment in chronic otitis media, but it is unclear that raised bone conduction threshold is due to the reflection of cochlear dam- age and / or Carhart effect ( an artificial elevation of bone conduction threshold due to conductive defect ) or both. The purpose of this study is to verify the influence of the artificial elevation of the bone conduction threshold in chronic otitis media and to estimate Carhart effect. A total of 336 cases of tympanoplasty with unilateral chronic otitis media without any other causes of sensorineural hearing loss was studied. The average threshold levels of the bone conduction in diseased ears ranged from 18.5dB at 4kHz to 12.1dB at 250Hz The longer duration of the disease, the larger perforation size, the more severe damage of the middle ear structure and the presence of the cholesteatoma made bone conduction threshold increased. The postoperative thresholds of bone conduction were Improved in 36 cases (40.4%) of the 89 cases that underwent operation with type I tympanoplasty technique without electrie drilling. The degree of the maximal improvement was 14.3dB at 2000Hz and the minimum was 8.8dB at 250Hz. but these result did differ from a statistically significant degree. The result suggest that the bone conduction threshold in chronic otitis media is elevated artificially by conductive defect and improved by successful reconstructive surgery.

가와사끼 병 환아에서 이상뇌파와 신경학적 합병증 발현과의 연관성에 대한 고찰

박준수,공도연,박경배,민용식,김영창,정순이,이혜경 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.2

목적 : 가와사끼 병의 뇌파 소견 및 다른 임상인자들과의 연관성을 알아보고자 하였다. 방법 : 1994년 1월부터 1995년 12월 사이에 순천향대학 천안병원 소아과에 입원한 23명의 신경학적으로 정상인 가와사끼 병 환아에게 뇌파검사를 실시하여 이를 검사시기, 성별, 연령, 혈소판, 간기능 검사치, 그리고 동맥류 유무등의 임상인자들과 비교하였다. 결과 : 이상뇌파가 23명중 52.2%인 12명에게서 관찰되었으며, 이상뇌파로는 예파 및 극파, 극·서파 복합 양상과 전반적인 배경파의 서파양상이 나타났다. 뇌파의 검사시기가 진단부터 1주 이내인 경우에 이상뇌파의 빈도가 그 후보다 의미있게 높았으나, 그 밖의 다른 임상인자와의 연관성은 별 의미가 없었다. 결론 : 가와사끼 병 초기에 이상뇌파가 나타나는 것은 비록 신경적 증상은 없지만 중추 신경계가 영향을 받는다는 간접적인 증거로 생각할 수 있어 향후 신경적 합병증 발생 여부에 대한 면밀한 관찰이 필요하다고 생각된다. Purpose : This study is to find out if there is any association between EEG abnormalities in Kawasaki disease with other clinical factors. Methods : We performed EEG in 23 Kawasaki disease patients without any neurologic sign who admitted in Soonchunhyang Chunan Hospital from 1994. 1. to 1995. 12. and compared it with sex, age, platelet count, liver function test and presence of coronary artery aneurysm. Results : Abnormal EEG findings were observed in 12 of 23 patients(52.2%) and as for abnormal EEG findings, sharp, spike, spike & slow wave complex, and generalized slow background activity were noted. When EEG was performed within a week after the diagnosis, the incidence of abnormalities of EEG increased significantly but there was no correlation with other clinical factors. Conclusion : EEG abnormalities in the early stage of Kawasaki disease indicate that although there is no abnormal neurologic signs clinically, central nervous system might be affected and there should be a close observation for the developement of neurologic complication.

비강 및 부비동 종양에서의 종양혈관형성에 관한 면역조직화학적 연구

도남용,노용훈,박선홍 조선대학교 부설 의학연구소 2002 The Medical Journal of Chosun University Vol.27 No.1

Background and Objectives : Angiogenesis is essential for the growth of solid tumors. Microvessel density(MVD), which represent a measure of tumor angiogenesis, have been found to have prognostic significance in many tumor types for predicting an increased risk of metastasis. However, the significance of angiogenesis in sinonasal malignant tumor remains controversial. The purpose of this study was to asses the tumor vascularity using the highly specific endothelial cell marker CD34, and the expression of its related protein p53, in sinonasal malignant tumors. Materials and Methods : The study samples were obtained after surgical removal of 27 cases of inverted papilloma(IPs), 5 cases of IPs with malignant transformation(IP-MT), 16 cases of squamous cell carcinoma(SCC) in sinonasal cavity. Microvessels were stained with anti-CD34 and p53 expressions were assessed by immunohistochemical staining. Results : The degree of tumor angiogenesis in squamous cell carcinoma group was higher than in inverted papilloma group, and which reached at highest level in IP-MT(p<05). The p53 expressions were increased as tumor progressed, which was statistically significant also(p<05). Significant correlation between MVD and p53 expressions was observed in IP(p<05) but there were no correlation in IP-MT and SCC. Conclusions : These results suggest that overexpression of p53 and MVD in the sinonasal tumors seemed to be associated with tumorigenesis but further studies on tumor angiogenesis of sinonasal tumors are needed before it can be adopted as a prognostic marker.

슬관절 골관절염 증상이 환자에게 미치는 우울 효과

박영규,이윤영,이계우,김정아,윤도경,박승회,조경환,홍명호,박용규 대한노인병학회 2001 대한노인병학회지 Vol.5 No.4

LED를 이용한 복합레진의 광조사시, 중합수축의 속도와 양, 미세경도에 관한 연구

박성호,김수선,조용식,이순영,김도현,장용주,문현승,서정원,노병덕 大韓齒科保存學會 2003 Restorative Dentistry & Endodontics Vol.28 No.4

This study evaluated the effectiveness of the light emitting diode(LED) units for composite curing. To compare its effectiveness with conventional quartz tungsten halogen (QTH) light curing unit, the microhardness of 2mm composite, Z250, which had been light cured by the LEDs (Ultralume LED2, FreeLight, Developing product D1) or QTH (XL 3000) were compared on the upper and lower surface. One way ANOVA with Tukey and Paired t-test was used at 95% levels of confidence. In addition, the amount of linear polymerization shrinkage was compared between composites which were light cured by QTH or LEDs using a custom-made linimeter in 10s and 60s of light curing, and the amount of linear polymerization shrinkage was compared by one way ANOVA with Tukey. The amount of polymerization shrinkage at 10s was XL3000 > Ultralume 2, 40, 60 > FreeLight, D1 (P<0.05) The amount of polymerization shrinkage at 60s was XL3000 > Ultralume 2, 60 > Ultralume 2, 40 > FreeLight, D1 (P<0.05) The microhardness on the upper and lower surface was as follows; <본문 참조> It was concluded that the LEDs produced lower polymerization shrinkage in 10s and 60s compared with QTH unit. In addition, the microhardness of samples which had been cured with LEDs was lower on the lower surfaces than the upper surfaces whereas there was no difference in QTH cured samples.

볶음보리 추출물의 아질산염 소거인자

도정룡,김선봉,이용우,구연숙,박영호 한국노화학회 1991 한국노화학회지 Vol.1 No.1

WHO 침구임상 지침서 개정을 위한 국제회의 보고

박히준,서정철,김세현,김상우,안경애,임사비나,김용석,최도영,강성길 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

The Working Group on the revision of Clinical Research Methodology for Acupuncture met in Seoul, Republic of Korea from 24 to 26 August 2005. The main objectives of the meeting were to review the regional publication guidelines for Clinical Research on Acupuncture, to make necessary revisions in the guidelines, to make recommendations on further collaboration and activities in the field of research on acupuncture, and to discuss scientific evidence-based approaches in the clinical research on acupuncture. Fourteen members from the eight Member States, one secretariat staff from the WHO Regional Office for the Western Pacific and ten observers from the Republic of Korea attended the meeting. The members presented their papers to review the current status of clinical research on acupuncture. The drafts of proposed revision to the previous guidelines for clinical research methodology on acupuncture were discussed extensively. The issues covered during the discussion included: the definition of the new terms; reorganization of clinical research design; revision and update of contents (e.g., control group); introduction of Institutional Review Board (IRB) on the section of ethical approval; additional outcomes including health-related quality of life (HRQOL), qualitative measures, etc. In the course of these discussions, the working group developed the revised guidelines for clinical research on acupuncture and made recommendations for promoting the dissemination of the revised guidelines.

흰쥐 腦의 中心扁桃核에서의 Substance P 및 Enkephalin 함유구조의 형태학적 특징

마도훈,조희중,김은희,박매자,배용철,홍해숙,주강 慶北大學校 醫科大學 1990 慶北醫大誌 Vol.31 No.4

흰쥐 뇌의 중심편도핵에서의 substance P (SP) 및 Enkephalin (ENK) 함유신경세포 및 축삭종말의 분포를 관찰하기 위하여 peroxidase antiperoxidase법을 행하여 다음의 결과를 얻을 수 있었다. SP함유신경세포는 중심편도핵의 medial zone에 분포하였고 SP함유축삭종말은 lateral capsular zone에서 고밀도로 관찰되었다. SP함유신경세포는 원형 내지는 타원형이었고 2∼3개의 근위수상돌기(proximal dendrite)를 가졌다. ENK함유신경세포 및 축삭종말은 공히 central 및 lateral capsular zone에 존재하였다. ENK함유 신경세포는 직경이 약 17-24㎛ 정도였고 3∼4개의 근위수상돌기를 관찰할 수 있었다. The central amygdaloid nucleus is rich in a number of neuropoptides. The present study examines the distribution and morphological characteristics of substance P (SP) and leucine-enkephalin (ENK) containing neurons in this nucleus. The results obtained were as follows: SP immunoreactive cells were observed within the medial zone and SP immunoreactive axon terminals were heaviest within the lateral capsular zone. The immunoreactive cells were round or oval shape (diameter, 15-20㎛) and had two or three proximal dendrites. ENK immunoreactive cells and axon terminals located within central and capsular zones. The immunoreactive cells were round or oval shape (diameter, 17-24㎛) and had three or four proximal dendrites.

Banana 栽植樣式이 生育과 收量에 미치는 影響

吳現道,朴才昊,金龍湖 濟州大學校 亞熱帶農業硏究所 1987 亞熱帶農業硏究 Vol.4 No.-

本 試驗은 1985年 3월 부터 1986年 3月에 걸쳐 栽植樣式이 生育과 收量에 미치는 影響을 究明하기 위하여 濟州大學校 亞熱帶農業硏究所 plastic film house에서 遂行되었다. 그 結果를 要約하면 다음과 같다. 바나나의 草長, 葉數, 葉幅, 葉長, 果掌數, 果房重은 栽植樣式에 따라 影響을 받지 않았으나 假莖長, 假莖直徑, 抽穗期, 成熟期는 有意性이 인정되어 正方形, 三角形, 長方形, 栽植樣式 順으로 假莖長과 假莖直徑이 增加하였고 抽穗期와 成熟期도 短縮되었다. 果掌當 果指數와 果掌重은 栽植樣式에 따라 1段에서 差異가 있었고 長方形, 三角形 栽植樣式에서 2段에서는 현저하게 감소하였으나 3段 이후부터는 緩慢하게 감소되는 傾向을 나타내었다. 果掌當 果指長과 果指直徑은 1段에 比해 2段에서 增加하였는데 長方形, 正方形, 栽植樣式에서 1段∼2段 差가 컸으며 果指直徑의 變化는 栽植樣式 및 果掌間에 따라서 差異가 크게 나타났다. 正方形, 三角形 栽植樣式에서 1段에 比해 2段 果指重이 增加하였으나 3段 이후부터는 감소되는 경향을 나타내고 栽植樣式 및 果掌間에 따라 差異가 컸다. This experiment was carried out to elucidate the influence of spatial arrangement at planting on the growth and yield in bananas (Musa cavendish Lambert 'Dwarf Cavendish') from March, 1985 to March, 1986 in the plastic film house at Research Institute for Subtropical Agriculture, Cheju National University, Cheju, Korea. The results obtained are summarized as follows. Plant height, no. of leaves, leaf width, leaf length, no. of hands, and bunch weight, were little affected by planting pattern. However, pseudostem length and diameter were greater and date of emergence and maturity were earlier in the order of regular, triangular, rectangular planting. The number of fingers/hand and hand weight were significantly affected by planting pattern in 1st hands and decreased remarkably in 2nd hand of the rectangular and triangular planting, but tended to be decreased slowly from 3rd hand. Finger length and diameter/hand were greater in 2nd hand than in 1st hand and more significant in the difference of 1-2 hands in rectangular and regular planting than that of triangular planting, finger diameter/hand were afected remarkably by planting pattern or hands. Finger weight/hand were increased in 2nd hand against 1st at regular and triangular planting, but tended to be decreased from 3rd hand and affected by planting pattern or hands.

다발성 골수종으로 이행한 단일형질세포종 1예

정재용,모성환,기장도,문철호,김창욱,전용준,박유환,정춘해,오윤경 조선의대 1995 The Medical Journal of Chosun University Vol.20 No.2