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        광주·전남 지역에서 발생한 스포로트리쿰증 103예에 대한 임상적 고찰(1967-1996)

        전인기,김훈희,김성진,이승철,원영호 대한의진균학회 1997 대한의진균학회지 Vol.2 No.2

        Background : Sporotrichosis is most common deep cutaneous fungal disease in Korea. It is markedly variable in incidence, distribution, and colinical pattern. The epidemiology have been well known to change over years, and to be influenced by environmental condition and geographic location. Sporotrichosis in Kwangju and Chonnam area is more prevalent compared to other areas in Korea. Objective : Our purpose was to describe the prevalence, epidemiological and clinical features, regional distribution and the change of the incidence according to the climate in different regions. Method : the observation of 103 sporotrichosis patients confirmed by clinical, histopathological and mycological studies had been made in the Department of Dermatology at Chonnam National university Hospital for thirty years from 1967 to 1996. Results and Conclusion : The sporotrichosis patient was 0.09% of 108, 680 outpatients, prevalent at the age of thirties and forties(20%), and 3.2:1 in the ration between male and female. The 58% of total cases visited us within 3 months after the beginning of skin lesion. Almost all initial lesions appeared on the exposed areas, especially upper extremities(68%). The 74% of the total cases was lymphocutaneous type, and the rest was fixed cutaneous type. Most popular occupation of patients was farmer(60%). The 69% of patients visited in spring and winter, especially in february(17%). The incidence of sporotrichosis per average 100,000 population in districts of Kwangju and Chonnam area revealed a difference with the amount of rainfall in winter; average 1.8 person in an area above 125㎜,0.8 person in an area between 100㎜ and 125㎜, and 0.2 person in an area below 100㎜ These rsults suggest that the incidence and clinical features of sporotrichosis are influenced by occupations, leisure and occupational activities, living conditions, and the climate.

      • 근자외선 레이저를 위한 Ar 섬광관의 방전 특성과 BBQ의 형광 강도

        吳喆漢,林春雨,朴成珍 慶北大學校 1992 論文集 Vol.52 No.-

        The fluorescence characteristics of near UV dye, BBQ, pumped by Ar flashlamp have been studied for various electrical input energies applied to the flashlamp and argon fill pressures in the flash tube. The peak wevelength of fluorescence is about 380nm when the fluorescence intensity is at the peak value. The rise time of the fluorescence pluse is about 7μsec and its FWHM is about 55μ sec When the input energy is 72J. The fluorescence energy increases linearly with the input energy and the fluorescence energy in creases as Ar fill pressure in the flash tube increases, but it decreases over 170Torr of Ar pressure. Therefore, the optimum pressure of the tube for fluorescence emission is 170Torr.

      • KCI등재후보

        이황화탄소 폭로 남성 근로자의 진동감각 역치에 관한 연구

        박승희,이은일,천병철,염용태,최재욱 大韓産業醫學會 1996 대한직업환경의학회지 Vol.8 No.1

        This study was conducted on 367 male workers to evaluate the change of vibration perception threshold(VPT) according to exposure degree to carbon disulfide. VPT was measured on both metacarpal bones of index and little fingers and on fibular malleoli by Vibrometer(Rion, on 125Hz). The exposure degree was classified by the name of department. Workers in department 2 had been exposed to carbon disulfide, those in department 3 had been exposed to undetectable concentration of carbon disulfide. The results were as follows: 1. The mean values of VDT of metacarpal(MC) bones showed dose-response pattern, i.e., the mean values of VPT at department 1 were highest, and those of VPT at department 3 were lowest with similar work duration or age. But the mean values of VPT of fibular malleoli(FM) showed dose-response patter only in workers having above 5 years of work duration or whose age were above 30. 2. The mean values of VPT of MC bone of workers increased by age. 3. There were statistically significant difference in mean values of VPT of MC bone only in workers having 5-10 year work duration. And there were statistically significant difference of mean values of VPT of left 2nd and 5th MC bone in workers whose age was 30's, of right 2nd MC bone in those whose age was 40's, and of left 2nd MC bone in those whose age was 50's. 4. The variables affecting VPT significantly were department and age(or age group) both in multiple regression and general linear model. The department showed to have more effect to VPT than age in multiple regression, but age group showed to have more effect to VPT than department in general linear model. 5. The variables were transformed to indicator variable to do logistic regression analysis. department 1, 2, 3 were classified into high exposure(spinning department) and low duration was classified into long(above 10 years) and short. The exposure and age were significant variables by logistic regression analysis. Odds rations of department and VPT on metacarpal bones or malleoli were 2.7-3.2 and VPT those were 2.6 or 2.7. Odds ratio of age and abnormality of VPT on any point was 3.3(1.59-6.8), and that of department and VPT was 2.8(1.5-5.5). We concluded that exposure of carbon disulfied was significantly associated with reduction of VPT regardless of age; and that the test of VPT would be useful tool for screening and early detection in neuropathy by carbon disulfide or other neurotoxic chemicals, even though it is simple and cheap.

      • 농촌지역 노인들의 우울증상에 관련된 요인들의 특성

        송미숙,전기홍,송현종,김정은,박승구,신상건,이동훈,정성현,최연주,최완철,최민규,황재철,홍지만 아주대학교 1997 아주의학 Vol.2 No.2

        This study was performed to identify risk factors for depression among the elderly in a rural area. A survey was done for the elderly living in Gosam-myenn, Ansung-kun during the period of July 28, 1997 and July 30, 1997. Demographic and sodoeconornic characteristics, and functional and health Status were assessed using a structured questionnaire, and the level of depression was measured by GDS score. The data obtained were analyzed by frequencies, percentage, t-test, ANOVA, and multiple regression, and the results were as follows: 1. The total sample consisted of 133 elderly. Of them, 47 elderly (35.4%) showed significant depressive Symptoms. 2. The GDS score was the highest for the group over 85 years of age (p < 0.05). Those living alone or widowed showed lower GDS score than those living with someone or married (p < 0.05). 3. The GDS score was the highest in the absolutely dependent group, followed by the partially dependent group, and the independent group (p < 0.01). The elderly who perceived their health Status as excellent showed the lowest GDS score. In contrast, those who had more than five chronic diseases showed the highest GDS score. 4. The elderly receiving financial and emotional support from their family or friends showed lower GDS score compared to those without any support. 5. The economically dependent group showed higher GDS score than that of independent group. 6. The elderly who involved in leisure activities showed lower GDS score than those without any involvement. 7. In terms of risk factors for depression, we found that perceived health Status, subjective economic Status, leisure activities, living arrangement and financial support were inversely associated with GDS score, whereas labor support was positively associated with GDS score. Based upon the above findings, this study suggests that these risk factors for depression in the elderly should be taken into consideration for a comprehensive mental health program for the elderly living in the rural area.

      • KCI등재
      • 발치 직후 시행된 즉시 임플란트 식립술에 관한 임상적 평가

        양은영,천상득,노재환,이승은,송재철,진병로 영남대학교 의과대학 2003 Yeungnam University Journal of Medicine Vol.20 No.1

        Background: Immediate implant placement has become an acceptable treatment for the edentulous area. The advantages of the immediate implant placement include considerable decrease in time from tooth extraction to placement of the finial prosthesis, fewer surgical procedures, and better acceptance of the overall treatment plans. But the success is dependent on the quantity and quality of the extraction socket. The purpose of this study is to evaluate the success of the immediate implant placement. Materials and Methods: Twenty-one sites in 16 patients were selected for the evaluation of the immediate implant placement. All of the cases were followed using clinical and radiographic examinations. Criteria of success were the absence of peri-implant radiolucency, mobility, and persistent pain or sign of infection. Results: Of the 21 implants, 13 implants have been succeeded. Of the 13 implants, 10 implants were replaced for the periodontal disease and 3 implants were replaced for the trauma. Conclusion: The criteria of the success in immediate implant placement are as follows. 1) Implants placed into fresh extraction sockets have a high rate of survival. 2) Implant should be placed as close as possible to the alveolar crest. 3) Implant placed into available bone beyond the apex have a high success rate.

      • SCIESCOPUSKCI등재

        징병 신체검사에서 나타난 청소년기 추간반탈출증의 유병률과 임상적 특징 : A Study Based on Examinations for Conscription

        홍창기,박철기,박형천,윤승환 대한척추신경외과학회 2004 Neurospine Vol.1 No.1

        Objective: The authors analyzed the large series of intervertebral disc herniation in adolescence to evaluate the prevalence, clinical characteristics, and possible risk factors on the basis of the data from the examinations for conscription. Material and Methods: Of 77685 nineteen-old-males who were given an examination for conscription at Regional Military Manpower Administration of Seoul in 2002, 382 patients exempted from conscription due to intervertebral disc herniation were analyzed. The diagnosis were made from the medical certificate, medical record, magnetic resonance imaging(MRI)(or computed tomography(CT)) which examinee presented and confirmed with the aid of reexamination of CT. Radiological char cteristics and severity of intervertebral disc herniation as well as structural abnormalities of vertebral columns were carefully evaluated with CT scan and MRI scan. Possible risk factors like overweight, structural abnormality of vertebral column, trauma were analyzed statistically using one-sample T-test and chi - square test on the assumption that P value less than 0.05 was considered statistically significant. Result: Prevalence of intervertebral disc herniation in adolescence aged nineteen years and younger were 0.5%. L4-5 level was the most frequently affected site followed by L5-S1. Of all 382 patients of intervertebral disc herniation, 29% were considered serious with reference to radiological evidence of root compression or siginificant discogenic spinal stenosis. Limbus fracture was found in 6.8% of patients. Overweight was the significant risk factor of the disease(p=0.0). However, neither structural abnormality of vertebral column nor trauma showed any relation to pathogenesis of intervertebral disc herniation. Conclusion: In adolescence aged nineteen years and younger, the prevalence of intervertebral disc herniation was 0.5% and accompanying limbus fracture was more frequent when compared with adult. Overweight was the only significant risk factor of the disease.

      • 분편 인플루엔자백신(split influenza vaccine)의 임상효과 및 면역원성에 관한 연구

        우흥정,김동림,정희진,천병철,이주연,안정배,김지희,박찬,신영규,김우주,김민자,박승철 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.1

        목적 : 아단위 인플루엔자 백신 접종 후 백신의 인플루엔자 예방효과, 인플루엔자 방어 항체형성, 인플루엔자 백신의 안전성을 조사하고자 하였다. 방법 : 총 571명을 대상으로 인플루엔자 백신 접종을 하였고, 이들 접종자에서 인플루엔자 양질환의 이환을 조사하여 인플루엔자 백신의 인플루엔자예방효과를 알아보았고, 백신의 접종 전 및 접종 4주 후 혈청에서 혈구응집억제물(Hemagglutination Inhibition : HAI) 항체 검사를 실시하여 백신의 방어항체생성을 조사하였고, 백신의 안전성을 알아보기 위해 백신접종 후 1주일 이내의 부작용을 조사하였다. 결과 :백신 접종군과 백신 비접종군에서 인플루엔자 양 질환의 이환을 조사한 결과 접종군 28.35%, 비접종군 35.88%으로 나왔으며, p 값이 0.001로 통계적으로 접종군에서 유의하게 낮았고, 인플루엔자 양 질환의 예방 효과는 20.97%를 보였다. 백신의 방어항체 형성의 평가를 위해 유럽의 인플루엔자 백신 허가 기준을 조사하였는데 B/Guangdong/5/94균주의 백신접종 후 항체가 40이상의 비율을 제외한 다른 기준은 모두 만족 시켰다. 부작용은 전체 조사자 521명중 149명(29%)으로 주로 접종 부위의 국소 부작용을 호소했고, 전신 부작용은 2% 내외였으며 특별히 심각한 부작용은 발견되지 않았다. 결론 : 분편 인플루엔자 백신은 인플루엔자양질환의 예방과 방어항체생성에 효과 있으며 안전한 것으로 사료된다. Background : The safety and effectiveness of influenza vaccine are well known in developed country. The influenza vaccination has been recommended as one of the tentative immunization schedule for indicated persons since 1997 in Korea. But there are still no available data about them, even though nearly 5 million doses of influenza vaccine were used in 1997-1998 season. So it is immediately needed to investigate the safety. efficacy and immunogenicity of influenza vaccine among Korean. Methods : We studied the clinical efficacy of influenza vaccine by monitoring Occurrence of influenza-like illness in influenza risk group(vaccination ; 300, non-vaccination; 215) from December in 1997 to March in 1998. We used the split quadrivalent influenza vaccine containing 15 microgram of hemagglutinin of A/Beijing/262/95(HlNl), A/Wuhan/359/95(H3N2), B/Mie/1/93 and B/Guangdong/5/94. Hemagglutination inhibition(HA1) antibody titers were determined before immunization and 1 months after vaccination And we evaluated adverse effect of influenza vaccination at 7 days after vaccination. Results : Influenza vaccination was associated with si@icant reductions in influenza-like spptoms(vaccination group; 28.35%, non-vaccination group, 35.88%, p=0.001). The preventive effect of influenza-like i3lne.s among influenza risk goup was 20.97%. And immunogenicity of influenza A and B exceeded all of the European licensure criteria for immunogenicity except postvaccination proportion of titers 240 of B/Guangdong/5/94 strain. And the adverse effects were mainly local injection site problem and no serious adverse effect was noted. Conclusion : Split influenza vaccine is safe, inmunogenic and eff'tive in influenza risk group in Korea.

      • SCIESCOPUSKCI등재

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