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      • KCI등재

        경추부 확장성 나사못의 인장 항력 : 생체역학적 연구 Biomechanical Study

        백광흠,이규석,오성훈,정진환,김재민,김충현 대한척추신경외과학회 2004 대한척추신경외과학회지 Vol.1 No.1

        Objective: Many factors have been studied to increase the pullout strength of spinal screws. Expansive screws from many manufacturers have been developed to increase the pullout strength in cervical and thoracolumbar screw fixation. The objective of this study is to determine how much an expansive cervical screw design could improve biomechanical fixation in cervical spine. Methods: There were 72 DOC^(?)(Depuy Acromed, Cleveland, USA) cervical screws that have a configuration of 12 mm in length and 4.0mm in diameter: There were 36 expansive screws and 36 regular non-expansive screws for control group. After pilot holes were either drilled or awled, the 36 screws in each group were inserted into the synthetic cancellous material in either 0˚ 20˚ 30˚ angle. The screws were extracted axially at a rate of 2.4mm/min using a servohydraulic machine. Pullout strength was recorded with a digital oscilloscope. The synthetic bone was underwent macroscopic examination after pullout. Results: The mean pullout force of the expansive screws was 371.42N ± 94.87 and the non-expansive screws was 362.99N ± 78.55. There was no statistical significance in pullout resistance between two groups. Also there was an evidence of crack in grain structure of synthetic bone that expansive screws were inserted. Conclusion: Expansive screw design does not increase pullout strength in cervical screws. The data represent only the primary stability of the screw because the present study design precluded any cycling testing.

      • KCI등재

        Dynamic Cord Compression Causing Cervical Myelopathy

        Andrei Fernandes Joaquim,Griffin R. Baum,Lee A. Tan,K. Daniel Riew 대한척추신경외과학회 2019 대한척추신경외과학회지 Vol.16 No.3

        Due to the highly mobile nature of the cervical spine, and the fact that most magnetic resonance imagings (MRIs) and computed tomography scans are obtained only in one single position, dynamic cord compression can be an elusive diagnosis that is often missed and not well-understood. In this context, dynamic MRI (dMRI) has been utilized to improve the diagnostic accuracy of cervical stenosis. We performed a literature review on dynamic cord compression in the context of cervical spondylotic myelopathy (CSM), with particular emphasis on the role of dMRI. Cadaveric studies report that the spinal cord lengthens in flexion and the spinal canal dimension increases, whereas the spinal cord relaxes and shortens in extension and the spinal canal decreases. These changes may lead to biomechanical stress in the spinal cord with movement, especially in patients with critical cervical stenosis. The majority of the studies using dMRI in CSM reported that this imaging modality is more sensitive at detecting cervical cord compression compared to routine MRIs done in a neutral position, especially with the neck in extension. Dynamic MRI was also useful to diagnose dynamic cervical cord compression after laminectomies in patients with clinical deterioration without evident cord compression on neutral static MRI. Finally, dMRI is more sensitive in detecting stenosis in patients with CSM than in those with ossification of the posterior longitudinal ligament (OPLL), likely because OPLL patients often have a more limited range of motion than CSM patients. Thus, dMRI is a promising new tool that can help spine surgeons in diagnosing and treating CSM.

      • KCI등재

        Outcome Measures and Variables Affecting Prognosis of Cervical Spondylotic Myelopathy: WFNS Spine Committee Recommendations

        Mehmet Zileli,Shradha Maheshwari,Shashank Sharad Kale,Kanwaljeet Garg,Sajesh K. Menon,Jutty Parthiban 대한척추신경외과학회 2019 대한척추신경외과학회지 Vol.16 No.3

        This study is conducted to review the literature systematically to determine most reliable outcome measures, important clinical and radiological variables affecting the prognosis in cervical spondylotic myelopathy patients. A literature search was performed for articles published during the last 10 years. As functional outcome measures we recommend to use modified Japanese Orthopaedic Association scale, Nurick’s grade, and Myelopathy Disability Index. Three clinical variables that affect the outcomes are age, duration of symptoms, and severity of the myelopathy. Examination findings require more detailed study to validate their effect on the outcomes. The predictive variables affecting the outcomes are hand atrophy, leg spasticity, clonus, and Babinski’s sign. Among the radiological variables, the curvature of the cervical spine is the most important predictor of prognosis. Patients with instability are expected to have a poor surgical outcome. Spinal cord compression ratio is a critical factor for prognosis. High signal intensity on T2-weighted magnetic resonance images is a negative predictor for prognosis. The most important predictors of outcome are preoperative severity and duration of symptoms. T2 hyperintensity and cord compression ratio can also predict outcomes. New radiological tests may give promising results in the future.

      • KCI등재

        Anterior Cervical Discectomy and Fusion for Hirayama Disease: A Case Report and Literature Review

        Yi-Hsuan Kuo,Chao-Hung Kuo,Wen-Cheng Huang,Jau-Ching Wu 대한척추신경외과학회 2019 대한척추신경외과학회지 Vol.16 No.3

        Hirayama disease, a juvenile muscular atrophy of the distal upper extremity, is a rare form of cervical flexion myelopathy characterized by insidiously progressive weakness of the hands and forearm muscles (i.e., painless amyotrophy). The pathognomonic finding is a markedly forward-shifted spinal cord during neck flexion, demonstrated by dynamic magnetic resonance imaging (MRI), as in a young man with muscle atrophy in the bilateral distal upper extremities. In this report, the authors describe a 31-year-old man who had the classic radiological and clinical presentations of Hirayama disease. Since prior medical treatment had been ineffective for years, he underwent multilevel instrumented anterior cervical discectomy and fusion (ACDF) to keep his subaxial cervical spine slightly-lordotic (nonflexion). His motor evoked potential amplitude improved immediately during the operation, and there were improvements of myelopathy and a modest reversal of muscle wasting at 1 year postoperatively. Postoperative dynamic cervical spine MRI also demonstrated minimal cord compression and elimination of the venous plexus engorgement dorsal to the thecal sac. Although Hirayama disease is benign in nature and frequently self-limiting, multilevel instrumented ACDF could be a reasonable management option.

      • KCI등재

        Cervical Spondylotic Amyotrophy: Case Series and Review of the Literature

        Toshiyuki Takahashi,Junya Hanakita,Manabu Minami,Yosuke Tomita,Tomoki Sasagasako,Ryo Kanematsu 대한척추신경외과학회 2019 대한척추신경외과학회지 Vol.16 No.3

        Objective: Cervical spondylotic amyotrophy (CSA) is a relatively rare entity caused by cervical degenerative spinal diseases and characterized by motor weakness accompanied by remarkable muscle atrophy in the upper extremities without significant sensory deficits or spastic paraparesis in the lower extremities. Postoperative outcomes and predictive prognostic factors vary among previous reports. In the present report, we describe the surgical results in patients who were surgically treated for CSA and present a literature review. Methods: In total, 33 patients with CSA were retrospectively analyzed. Correlations between the surgical outcome and the following factors were statistically analyzed: age, sex, type of impaired muscle, preoperative severity of motor weakness, number of levels of cord or root compression, presence of a T2 high-intensity area in the spinal cord, cervical kyphosis, and methods of surgical procedure. Results: On postoperative neurological evaluation, 25 patients (75.8%) had favorable outcomes and 8 had unfavorable outcomes (proximal type, 72.2%; distal type, 78.6%). Patients with favorable outcomes were significantly younger than those with unfavorable outcomes (p=0.013). Patient’s characteristics except for age and radiological factors were not correlated to surgical outcome. Conclusion: The present study focused on the surgical results in patients who were surgically treated for CSA along with updated information from a literature review. Improvement of motor weakness is expected with acceptable prevalence although higher age can be a negative factor. Surgical outcomes and predictive factors related to a poor prognosis were determined and compared with those of previous articles.

      • KCI등재

        Epidemiology of C5 Palsy after Cervical Spine Surgery: A 21-Center Study

        오재근,홍재택,강동호,김상우,김석원,김영진,정천기,신준재,이성,이정길,이준호,이창현,이호진,전형준,조대철,조용은,진용준,최경철,한인호,현승재,허정우,김기정 대한척추신경외과학회 2019 대한척추신경외과학회지 Vol.16 No.3

        Objective: C5 palsy is a severe complication after cervical spine surgery, the pathophysiology of which remains unclear. This multicenter study investigated the incidence of C5 palsy following cervical spine surgery in Korea. Methods: We conducted a retrospective multicenter study involving 21 centers from the Korean Cervical Spine Study Group. The inclusion criteria were cervical spine surgery patients between 2012 and 2016, excluding cases of neck surgery. In patients with C5 palsy, the operative methods, disease category, onset time of C5 palsy, recovery time, C5 manual muscle testing (MMT) grade, and post-C5 palsy management were analyzed. Results: We collected 15,097 cervical spine surgery cases from 21 centers. C5 palsy occurred in 88 cases (0.58%). C5 palsy was more common in male patients (p=0.019) and after posterior approach procedures (p<0.001). C5 palsy usually occurred within 3 days after surgery (77 of 88, 87.5%) and most C5 palsy patients recovered within 6 months (51 of 88, 57.95%). Thirty C5 palsy patients (34.09%) had motor weakness, with an MMT grade≤2. Only four C5 palsy patients (4.5%) did not recover during follow-up. Posterior cervical foraminotomy was performed in 7 cases (7.95%), and steroids were used in 56 cases (63.63%). Twenty-six cases (29.55%) underwent close observation only. Conclusion: The overall incidence of C5 palsy was relatively low (0.58%). C5 palsy was more common after posterior cervical surgery and in male patients. C5 palsy usually developed within 3 days after surgery, and more than half of patients with C5 palsy recovered within 6 months.

      • KCI등재

        A Radiological Study of the Association of Facet Joint Tropism and Facet Angulation With Degenerative Spondylolisthesis

        Ravi Ranjan Rai,Yash Shah,Siddharth Shah,Nigil Sadanandan Palliyil,Samir Dalvie 대한척추신경외과학회 2019 대한척추신경외과학회지 Vol.16 No.4

        Objective: To study the association of facet joint angulation and joint tropism with degenerative spondylolisthesis (DS) through a comparison with a matched control group. Methods: This radiographic study was carried out in 2 groups of 45 patients each. Group A contained patients with single-level DS, while group B (control) contained non-DS patients with similar age and degeneration who underwent surgery for disc prolapse or lumbar stenosis. DS was diagnosed based on translation of ≥3 mm on standing lateral radiography. Axial magnetic resonance imaging from L3 to S1 was utilized to assess the angulation of facet joints in relation to the coronal plane; a difference of ≥8° was considered to indicate tropism. Results: Among 45 patients with DS, 15 were males and 30 females. Their mean age was 62.2 years. Facet tropism was identified in 20 of 45 patients at the level of DS, 12 patients at a level proximal to DS, and 15 patients at a level distal to DS. Facet tropism was found in 7 of the 45 patients in group B. At L3–4, facet tropism was observed in 13 patients (28.88%) in group A and 2 (4.44%) in group B. At L4–5, tropism was observed in 19 patients (42.22%) in group A and 5 (11.11%) in group B. At L5–S1, tropism was seen in 17 patients (37.77%) in group A and 2 (4.44%) in group B. Group A showed a significantly higher prevalence of multilevel facet tropism and tropism at levels adjacent to the DS level. A higher average angulation of facet joints was observed in the DS group, but the difference was not statistically significant at all levels. Conclusion: The present study documented a statistically significant relationship between facet tropism and DS. A higher prevalence of facet tropism was also found in DS patients at non-DS levels, which is a novel observation. This finding supports the argument that facet tropism is a pre-existing morphological variation contributing to the development of DS, not a result of secondary remodelling.

      • KCI등재

        Deep Learning in Medical Imaging

        김민규,윤지혜,조용원,신기원,장령우,배현진,김남국 대한척추신경외과학회 2019 대한척추신경외과학회지 Vol.16 No.4

        The artificial neural network (ANN), one of the machine learning (ML) algorithms, inspired by the human brain system, was developed by connecting layers with artificial neurons. However, due to the low computing power and insufficient learnable data, ANN has suffered from overfitting and vanishing gradient problems for training deep networks. The advancement of computing power with graphics processing units and the availability of large data acquisition, deep neural network outperforms human or other ML capabilities in computer vision and speech recognition tasks. These potentials are recently applied to healthcare problems, including computer-aided detection/diagnosis, disease prediction, image segmentation, image generation, etc. In this review article, we will explain the history, development, and applications in medical imaging

      • KCI등재

        Towards Guideline-Based Management of Tethered Cord Syndrome in Spina Bifida: A Global Health Paradigm Shift in the Era of Prenatal Surgery

        Viachaslau Bradko,Heidi Castillo,Shruthi Janardhan,Benny Dahl,Kellen Gandy,Jonathan Castillo 대한척추신경외과학회 2019 대한척추신경외과학회지 Vol.16 No.4

        An estimated 60% of the world’s population lives in Asia, where the incidence of neural tube defects is high. Aware that tethered cord syndrome (TCS) is an important comorbidity, the purpose of this systematic review was to explore the treatment of TCS among individuals living with spina bifida (SB) in Asia. MEDLINE and Embase databases were searched for relevant studies published from January 2000 to June 2018. Search terms such as ‘spinal dysraphism,’ ‘spinabifida,’ ‘diastematomyelia,’ ‘lipomeningocele,’ ‘lypomyelomeningocele,’ ‘meningomyelocele,’ and ‘tethered cord syndrome’ were used in diverse combinations. Of the 1,290 articles that were identified in accordance with PRISMA (Preferred Items for Systematic Reviews and Meta-Analyses) guidelines, 15 Asia-based studies met the inclusion criteria. Significant differences in the diagnostic criteria and management of TCS were documented. As the surgical techniques for prenatal closure of the spinal defect continue to evolve, their adoption internationally is likely to continue. In this setting, a clear and evidence-based approach to the definition and management of TCS is essential. The recent publication by the Spina Bifida Association of America of their updated care guidelines may serve as a tool used to promote a systematized approach to diagnosing and treating TCS among individuals with SB in the region, as well as globally.

      • KCI등재

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