수술 후 담관 협착 환자에서 경피적 담관내시경 유도하 내시경적 담관 천자를 통한 담관배액술

황재철,김진홍,이윤철,유병무 대한췌담도학회 2010 대한췌담도학회지 Vol.15 No.1

기관선양 낭포암 환자에서 수술 후 발생한 단순포진 바이러스 폐렴

황재철,최영화,조혜진,오윤정,임현이,박광주,이이형 대한감염학회 2002 감염 Vol.34 No.1

해양경찰 항공 임무여건이 회전익 조종사의 피로도에 미치는 영향 연구- 공정문화 매개효과를 중심으로 -

황재철,김현덕 한국항공운항학회 2025 한국항공운항학회지 Vol.33 No.3

This study investigates factors influencing Fatigue Risk among helicopter pilots in the Korea Coast Guard aviation division. Maritime missions such as search and rescue, medical missions, and vessel deck landing procedures are characterized by high operational risk and unique fatigue accumulation patterns, as reflected in past crash cases. The research examines the structural relationships between Mission Conditions, Just culture, and Fatigue, based on the view that both physical and cultural factors contribute to pilot fatigue. Using survey data analyzed with SPSS v29.0 and PROCESS Macro v4.2, the results showed that among mission conditions, the operational environment had the strongest direct effect on fatigue. Ground duties and flight missions influenced Just culture, while the operational environment showed only a weak tendency. Mediation analysis further revealed that Just culture exerted a significant mediating effect on fatigue, confirming that organizational culture serves as an important pathway linking mission conditions to pilot fatigue. The findings demonstrate that pilot fatigue stems from the interaction of mission demands, physical settings, and organizational culture, suggesting the need for an integrated management approach in future aviation safety policies.

Suppressive Effect of Curcuma zedoaria ROSCOE on Pulmonary Metastasis of B16Melanoma Cells

황재철,김미랑,정용재,이영자,정운석,서운교 대한한의학회 2005 대한한의학회지 Vol.26 No.1

Purpoes: We examined the antimetastatic effect of Curcuma zedoaria ROSCOE(CZ) on pulmonary metastasis of B16 cells. Materials and Methods: For 6weeks, Zedoariae Rhizoma , made from the dried CZ were dissolved in distilled water and taken to mice 2weeks before they were injected with B16 melanoma cells. Mice were given CZ at doses of 250 and 500mg/kg, and we compared them in lung weight, survival days, NO production. Result: The intake of CZ throughout the experiment extended the average survival time. The intake after B16 cell injection slightly prolonged survival time, but The intake before B16 cell injection did not influence the life span. And we examined the effect of CZ on macrophage function by measuring NO production. After the macrophage being given CZ for 6weeks, the amount of NO generated by the macrophage stimulated with LPS in culture medium was increased. NO generated by the macrophages also served as a cytotoxic factor against B16 melanoma cells. B16 melanoma-conditioned medium reduced NO production by marcrophages. However, CZ treatment reversed the reduction in NO production by the conditioned medium significantly. Conclusion: These findings may suggest that macrophage function-modulating activity by CZ apperars to underlie its antimetastatic activity, which leads to a decrease in the number of lung metastatic surface nodules and the extension of life span.

Synthesis and Characterization of Novel Thermally stable, Transparent Norbornene based Polymers Films

황재철,최면천,하창식 한국고분자학회 2009 한국고분자학회 학술대회 연구논문 초록집 Vol.2009 No.4

Medical treatment of hepatolithiasis

황재철 대한췌담도학회 2012 대한췌담도학회지 Vol.17 No.1 (Suppl)

Hepatolithiasis can cause recurrent attacks of cholangitis or biliary cirrhosis. Definitive treatment should aim for complete elimination of bile stasis and removal of the entire stones. Endoscopic retrograde cholangiopancreatography is not well established for hepatolithiasis because of frequent failures due to associated biliary strictures, angulated ducts or peripherally impacted stones. Percutaneous transhepatic cholangioscopic lithotomy(PTCSL) for the treatment of hepatolithiasis is partic- ularly suited for those patients who poor surgical risks or who refuse surgery and those with previous biliary surgery or stones distributed in multiple segments. PTCSL is a relatively safe and effective for treating hepatolithiasis, and that complete stone clearance is mandatory to diminish the sequelae of hepatolithiasis. Intrahepatic duct stricture was the main factor contributing to incomplete clearance and stone recurrence. Long-term follow-up is required because the overall recurr- ence rate of hepatolithiasis is high and hepatolithiasis is also associated with cholangiocarcinoma. Oral dissolution therapy may be effective for the prevention of recurrence after removal of cholesterol hepatolithiasis by PTCSL.

기관선양 낭포암 환자에서 수술 후 발생한 단순포진 바이러스 폐렴

황재철,최영화,조혜진,오윤정,임현이,박광주,이이형 대한감염학회 2002 Infection and Chemotherapy Vol.34 No.1

스테로이드 유지요법에도 급격히 악화된자가면역 만성 췌장염 1예

황재철,유병무,고경현,김동훈,강창준,정재학,박병준,김진홍 대한소화기내시경학회 2008 Clinical Endoscopy Vol.37 No.1

자가면역 만성 췌장염은 자가면역성 기전에 의하여 췌장에 만성 염증이 유발되는 질환으로 대부분의 환자에서 스테로이드에 좋은 치료 반응을 보인다. 일부에서는 스테로이드 유지요법이 필요한 경우도 있으며, 유지요법 중 악화되는 경우도 있다. 저자 등은 재발 후 스테로이드 유지요법 중에도 급격히 악화되는 자가면역 만성 췌장염 1예를 경험하였다. 환자는 황달을 주 증상으로 내원하였고 췌장의 종대, IgG4의 상승, 주췌관의 다발성 국소 협착, 췌장 내 총담관의 협착 소견을 보였다. 환자는 초기에는 스테로이드 치료로 호전 소견을 보였으나 스테로이드 유지요법 중 급격히 악화된 소견을 보이는 증례를 경험하였기에 보고한다.

간내담석의 내과적 치료

황재철 대한췌담도학회 2012 대한췌담도학회지 Vol.17 No.2

Hepatolithiasis can cause recurrent attacks of cholangitis or biliary cirrhosis. Definitive treatment should aim for complete elimination of bile stasis and removal of the entire stones. Endoscopic retrograde cholangiopancreatography is not well established for hepatolithiasis because of frequent failures due to associated biliary strictures, angulated ducts or peripherally impacted stones. Percutaneous transhepatic cholangioscopic lithotomy (PTCSL) for the treatment of hepatolithiasis is particularly suited for those patients who poor surgical risks or who refuse surgery and those with previous biliary surgery or stones distributed in multiple segments. PTCSL is a relatively safe and effective for treating hepatolithiasis, and that complete stone clearance is mandatory to diminish the sequelae of hepatolithiasis. Intrahepatic duct stricture is the main factor contributing to incomplete clearance and stone recurrence. Long-term follow-up is required because the overall recurrence rate of hepatolithiasis is high and hepatolithiasis is also associated with cholangiocarcinoma. Oral dissolution therapy may be effective for the prevention of recurrence after removal of cholesterol hepatolithiasis by PTCSL.

경화성 담관염을 동반한 랑게르한스 세포 조직구증 1예

황재철,김도현,이은희,정재학,심진영,정재연,이기명,유병무,김진홍 대한소화기내시경학회 2003 Clinical Endoscopy Vol.26 No.1

Langerhans cell histiocytosis is a rare disorder with abnormal proliferation of histiocytes. Besides the infiltration of a variety of organs, patients with Langerhans cell histiocytosis can develop sclerosing cholangitis, with bile duct involvement, progressive fibrosis, and cirrhosis. We report a case of Langerhans cell histiocytosis with sclerosing cholangitis. Endoscopic retrograde cholangiopancreatography revealed multiple strictures and dilatations of left intrahepatic and extrahepatic bile duct. Endoscopic biopsy of common bile duct showed diffuse infiltration of histiocytes and eosinophiles in lamina propria. Immunohistochemical stain showed positive reactions for S-100 and CD1a and a negative reaction for cytokeratin in infiltrating histiocytes. (Korean J Gastrointest Endosc 2003;26:56-60) 랑게르한스 세포 조직구증이 담관을 침범하는 경우 경화성 담관염의 발생 및 담도폐쇄에 의한 담즙성 간경변으로 나타날 수 있다. 60세의 여자 환자가 2개월 동안 5 kg의 체중감소와 심와부통증을 주소로 내원하였다. 내원 당시 활력징후 및 신체 검사에서 이상소견은 없었고 검사실 소견에서 총 단백 7.1 g/dL, 알부민 3.6 g/dL, 총 빌리루빈 0.5 mg/dL, AST 68 U/L, ALT 77 U/L, ALP 618 U/L, γ-GT 1,202 U/L이었다. 간염 바이러스 검사에서는 HBsAg, HCVAb는 음성이었으며, HBsAb 양성이었다. 복부 전산화 단층촬영술에서 좌측간내담관 및 총담관의 확장과 간외담관벽의 비후를 보였다. 내시경적 역행성 담췌관 조영술에서 좌측간내담관과 간외담관에 다발성 협착 및 확장을 보여 경화성 담관염으로 진단하였으며, 관강 내 초음파검사에서 총담관 벽의 미만성 비후를 보여 총담관에서 겸자조직생검을 시행하였다. 조직병리학적 소견은 점막고유층에 조직구 및 호산구의 침윤이 있었고, 면역조직학적 염색 소견에서는 S-100 및 CD1a은 양성이었고 cytokeratin은 음성을 보여 담관에 발생한 랑게르한스 세포 조직구증으로 진단되었으며, 진단 후 증상의 악화 없이 경과 관찰 중이다.