한외여과된 돈혈청으로부터 DEAE - Sephacel Chromatography 에 의한 면역단백질의 분리

전기홍,유익종,박우문,이무하 ( K . H . Jeon,I . J . Yoo,W . M . Park,M . H . Lee ) 한국축산학회 1997 한국축산학회지 Vol.39 No.1

Concentrated porcine serum with ultrafiltration 30KDa was purified with DEAF-Sephacel column chromatography. Buffer solution with pH 7 to 9 and buffer concentration with 0.01M to 0.05M, and NaCl gradient with 0M∼0.5M, 0M∼0.8M and 0M∼1.0M were used respectively for chromatographic purification. Optimal conditions were at pH 8.0, buffer conc. 0.03M and salt conc, 0M∼0.5M with immunoprotein concentration 82% and production yield 43%. Purified immunoprotein was identified in the molecular weight 50KDa and 15KDa by electrophoresis.

종합전문요양기관 인정기준 모형 개발

전기홍,강혜영,강대룡,남정모,이계철 한국보건행정학회 2005 보건행정학회지 Vol.15 No.4

This study was conducted to verify the current criteria and classification system used to determine specialized general hospitals status. In this study, we proposed a new classification system, which is simpler and more convenient than the current one. In the new classification system, clinical procedure was chosen as the unit of analysis in order to reflect all the resource consumption and the complexities and degree of medical technologies in determining specialized general hospitals. We developed a statistical model and applied this model to 117 general hospitals which claim their national insurance through electronic data interchange(EDI). Analysis based on 984 clinical procedures and medical facilities' characteristic variable discriminated specialized general hospital in present without misclassification. It means that we can determine specialized general hospital's permission in new way without using the current complicated criteria. This study discriminated specialized general hospital by the new proposed model based on clinical procedures provided by each hospital. For clustering the same types of medical facilities using 984 clinical procedures, we executed multidimensional scale analysis and divided 117 hospitals into 4 groups by two axises : a variety of procedure and the proportion of high technology procedure. Therefore, we divided 117 hospitals into 4 groups and one of them was considered as specialized general hospital. In discrimination analysis, we abstracted proportion of 16 clinical procedures which effect on discriminating the specialized general hospital in statistical system, also we identify discriminating function which include these variables. As a result, we identify 2 discriminating functions, one is for current discriminating system, and the other two is for new discriminating system of specialized general hospital.

우리나라 만성질환 관리를 위한 질환주치의 모형의 타당성 분석

전기홍,백경원,이수진,박종연 한국보건행정학회 2009 보건행정학회지 Vol.19 No.3

This study suggests a model for continuing and comprehensive management of hypertension or Type 2 diabetes mellitus (T2DM) in Korea. Moreover, this paper computed the contribution cost of hypertension or T2DM management using the healthcare medical cost, which could have occurred from stroke, myocardial infarction (MI), and end-stage renal disease (ESRD) that were successfully prevented from the effective hypertension or T2DM management. Additionally, these costs were compared with the cost of implementing the hypertension or T2DM management model suggested in this study. This study used the medical fee summary of the health insurance claims submitted to National Health Insurance Corporation by medical facilities for services provided during the period from January 1st 1999 to December 31st 2006. The prevalence rate with treatment referred to cases in which patients submitted their medical claims at least once during the period, along with an accordant diagnosis. The incidence rate with treatment referred to cases in which patients who never submitted claims for the accordant disease during the five years from 1999 to 2003 submitted claims for the accordant disease in 2004 and 2005. The relative risk of the occurrence of stroke, MI and ESRD was 11.0, 13.6, and 30.3, respectively. The attributable risk of hypertension or T2DM for stroke was 0.730, and that for MI and ESRD were 0.773 and 0.888, respectively. Based on these, the contribution cost of hypertension or T2DM is estimated to be 986.3 billion Korean Won(KRW) for stroke patients, 330.5 billion KRW for MI patients, and 561.7 billion KRW for ESRD patients as in 2005. Hence, the total contribution cost of hypertension or T2DM to stroke, MI, and ESRD is 1.878 trillion KRW. The estimate for operational costs included an annual expenditure of 50,000 KRW per each recipient and an annual subsidy of 0.22 million KRW per person for he 1.6 million low-income individuals with hypertension or T2DM to cover their out-of-pocket medical expenses. Under this assumption, it took approximately 0.6 trillion KRW to manage 5 million high-risk patients in the low- and mid-income range, coverings up to 50% of costs. In conclusion, considering the potential benefits of preventing stroke, MI, and ESRD, the costs seems to be reasonable.

식육부산물 생산 현황 및 이용

전기홍,Jeon, Ki-Hong 한국축산식품학회 2013 축산식품과학과 산업 Vol.2 No.2

의료보험 본인부담금 인상에 따른 외래이용 변화

전기홍,김한중,Chun, Ki-Hong,Kim, Hang-Jung 대한예방의학회 1992 예방의학회지 Vol.25 No.1

The level of copayment increased in order to stabilize the financial condition of the health insurance on 1986. An important question regarding the policy was whether the increase in the level of copayments reduced the utilization of medical services in the poor selectively. In spite of the importance of the research question, no study has been reported. This study was designed to find out changes in numbers of physician visits, to explain characteristics influencing the difference of utilization before and after the program. Finally the interaction effect between the program and the level of income was examined for the abover question. A total of 10,421 persons from eight institutions was selected as the study sample. Research findings are as follows. 1. The number of physician visits decreased by ten percent as a result of increasing the level of copayment. 2. The decrease was remarkable in some groups such as children, rural area and large family. 3. The most important factor which explained the difference was the number of physician visits before the introduction of the new program. The more numbers of physian visits during the last year were, the more numbers of physian visits decreased after the program. 4. The interaction term between the program and the level of income was statistically significant in the multiple regression model which explained physician visits and its coefficient was negative. It means that an increase in copayment did not reduced the number of physician visits in the poor, selectively. 5. It can be concluded that imposing adequate copayment reduces the use of medical services as well as medical costs without serious damage in access especially for the poor people.

병원 경영수지에 영향을 미치는 요인 분석

전기홍,조우현,Chun, Ki-Hong,Cho, Woo-Hyun 대한예방의학회 1993 예방의학회지 Vol.26 No.3

Financial stability is the foremost prerequisite for the continuous growth and development of hospitals. The present study aimed at developing a deterministic model using the factors which affect the hospitals profitability and at discovering which factor affected the hospital profitability. The study conducted questionnaire surveys on all general hospitals, with the exception of special hospitals, with over eighty hospital beds. Of the 274 subject hospitals, 136 of them, consituting 49.6% of the whole, were used in the study. The results are as follows. 1. In the deterministic model, outpatient revenue was affected more by the number of physician visits than by outpatient service intensity. Inpatient revenue was found to be affected more by the number of discharged patients than by inpatient service intensity. However, the increase rate of the service intensity not only contributed in stepping up the operating margin by $4{\sim}8%$ in outpatient and $3{\sim}6%$ in inpatient, but it was statistically significant. 2. Among the factors which determined the operating cost within the deterministic model, the number of patients had a greater impact on the operating cost than the resource consumption per patient. 3. The resource consumption per patient were proved to have the greatest effect on the profitability within the probabilistic model. The management cost per adjusted patient, in particular, was proven to have a statistically significant effect on the profitability in all hospitals.

염지액농도, 염지시간 및 염지압력에 따른 계란의 염 침투효과

전기홍,유익종,장윤희,강통삼 한국가금학회 1993 한국가금학회지 Vol.20 No.3

This study was performed to find the desirable conditions for processing salted hard-boiled egg without cracking egg shell in NaCl solution under pressure. Among the many factors affecting saltiness of the shell egg, concentration of NaCl solution(0~40%), different salting time(0~45h) and salting pressure (0~4.5kg/$\textrm{cm}^2$) were employed to identify the permeability of NaCl into shell egg at ambient temperature. The saltiness of the shell egg was proportionally risen as concentration of NaCl solution, salting time and pressure increased. The most desirable saltiness was observed at the 0.70~1.00% of NaCl in albumen and 0.40~0.45% in yolk, Besides the saltiness, sensory evaluation of the shell egg were carried out to evaluate the quality of the salted shell egg. The effect of various concentration of NaCl solution, salting time and pressure on sensory scores of hard-boiled salted eggs showed that 20~40% of NaCl solution, 12~20 h of salting time, 3~4.5 kg/$\textrm{cm}^2$ of salting pressure were proper conditions for processing the product. These results indicate that the desirable condition to get salted hard-boiled shell egg were ; 30% of NaCl solution, 16h of salting time and 4.0kg/$\textrm{cm}^2$ of salting pressure.

[P3-54] 광파(lightwave)처리가 어린(fish scale)과 어피(fish skin)의 콜라겐 추출에 미치는 영향

전기홍,이남혁,김영붕,김영호,김영언,김인호,김현경,이진영 한국식품영양과학회 2008 한국식품영양과학회 학술대회발표집 Vol.2008 No.10

제 1 주제 : 병원경영 성과평가 / 병원의 활동기준원가 산출

전기홍 한국병원경영학회 2000 한국병원경영학회 학술대회연제집 Vol.2000 No.1

일개 대학병원의 당뇨병환자들의 진료비 분석(1996~2005)

전기홍,이관우,김대중,김혜진,백경원,이수진 Korean Diabetes Association 2008 Korean diabetes journal Vol.32 No.4

연구배경: 이 연구는 당뇨병에 사용되는 비용의 크기를 알고자 한 연구이다. 당뇨병의 의료기관 치료 개입에 따른 당뇨병 합병증 발생을 관찰하는 임상 코호트 연구의 사전 연구로서 진행되었다. 일개 대학병원의 지난 10년간 당뇨병 진단 환자의 진료 내역을 사후적으로 추적하여 진료비의 크기와 변화 양상을 비교하고자 하였다. 방법: 일개 대학병원에서 1996년부터 2005년까지 한번이라도 당뇨병으로 진단된 환자들의 최초 병원방문 시점부터 2005년 말까지 개인별 외래와 입원이용, 진료비와 투약 내역 자료를 사용하였고, 외래와 입원 진료비의 변화를 연차별로 분석하였다. 결과: 합병증 없는 당뇨병환자에서 당뇨병약 투약 후에 외래약제비는 월평균 약 25,000원 정도 증가하였고 미세혈관 합병증이 있는 당뇨병환자에서 당뇨병약 투약 후에 외래약제비가 월평균 약 35,000원 증가하였다. 결국 외래진료비는 고혈압 동반 여부와 상관없이 당뇨병약 투약 후에 외래약제비 증가만큼 크게 증가하여 당뇨병 약제비의 영향을 크게 받는 것으로 나왔으나, 총 진료비는 당뇨병약 투약 전보다 30~40% 감소하였다. 고혈압을 동반하지 않은 당뇨병환자의 당뇨병약 투약 후에 외래약제비는 연차별로 지속적으로 증가하였으며, 6년 후에는 고혈압을 동반한 당뇨병환자보다 더 많은 외래약제비를 사용하였다. 입원과 외래를 합친 총 진료비의 경우 심근경색이나 말기신부전은 발생 전 보다 총 진료비가 2배 이상 증가하였다. 뇌졸중은 외래약제비, 총 진료비에서 모두 가장 낮아 심각성에 비해 비용은 적은 것으로 나타났으며 말기신부전은 총 진료비가 가장 높아 비용 소요가 많은 합병증임을 알 수 있었다. 최종 결과질환 합병증을 가진 당뇨병환자의 진료비가 합병증 발생 후에 첫해에는 크게 높았다가 그 다음해에 감소한 후 연도별로 증감의 변화 없이 지속적으로 높은 양상을 보였다. 이는 합병증 발생 환자의 진료비 부담이 생애 기간 동안 지속적으로 큼을 의미한다. 결론: 당뇨병환자의 진료비는 당뇨병약 투약 여부가 외래진료비를 결정하는 가장 중요한 요인이다.