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전희대,이성열,이혜진,박영립,이종석,황규왕 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.2
In 3 months randomized, double-blind, vehicle-controlled study of retinol (vitamin A 0.1%-3000IU/g) in the treatment of photoaging skin, especially eye wrinkles. 24 patients applied retinol contained cream to the both eye wrinkles and vehicle cream(placebo) to the same site. Half of the patients received retinol contained cream and half received vehicle cream(placebo). All 24 patients who completed the study showed statistically significant improvement in photoaging eye wrinkles on the retinol contained cream treated group, but not on the vehicle treated group. Eight of the 12 patients who received retinol contained cream to eye wrinkles had improvement in photoaging, whereas only three of the 12 patients who received vehicle cream(placebo) improved. In retinol contained cream group, there is a some relationship between water contents and effects. In other words, as water contents were the higher, effects were the better. The side effects were limited to mild irritation of retinol contained cream treated skin. Retinol contained cream appeared to be safe and effective in the treatment of eye wrinkles.
황종대(Jong Dae Whang),박창수(Chang Soo Park),배덕수(Duk Soo Bae),이제호(Je Ho Lee),노정수(Jeong Soo Noh),김정식(Jeong Sik Kim),주인숙(In Sook Joo) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.1
Extraperitoneal inguinal endometriosis often presents as an inguinal mass in women of reproductive age, Approximately 40 cases of inguinal endometriosis have been documented in the sutgical and gynecological literature. The overall incidence is in the range of 0.4% of patients with endometriosis. The right side is much more commonly involved than the left (almost 90% of the time in one series of 23 patients), and rarely is the condition bilateral. The most frequent complaint of patients with inguinal endometriosis is an inguinal mass, followed by pain and enlargement of the mass near menstruation. Authors have experienced two cases of endometriosis of the extraperitoneal portion of the round ligament of uterus and report with a brief literature review.
적극적 관찰요법을 시행한 임신 2기 조기 양막파열의 주산기 예후
황종대(Jong Dae Whang),노정래(Cheong Rae Roh),양순하(Soon Ha Yang),이지수(Ji Soo Lee),김우영(Woo Young Kim),유진경(Jin Kyung Yoo) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.2
목적 : 본 연구는 임신 2기 조기 양막파열에 있어서 관찰요법후의 주산기 예후를 알아보고자 실시하였다. 방법 : 임신 20-28주에 조기 양막파열된 32례에 대하여 후향적 관찰연구를 시행하였다. 산과적 처치의 목표는 일차적으로는 관찰요법을 통하여 임신 32주까지 분만을 지연시키는 것이고 이차적으로는 집중감시와 적극적인 처치를 통해 태아 안녕을 유지시키는 것이었다. 모든 산모와 신생아의 의무기록을 검토하였다. 결과 : 임신 20-28주에 조기 양막파열된 총 30명의 산모가 연구대상에 포함되었으며 조기 양막파열의 시점은 14례에서 20-25주(평균 24.2주)였고 16례에서 26-28주(평균 27.2주)이었다. 분만까지의 잠복기의 중앙값은 임신 20-25주에 조기 양막파열된 경우는 309시간, 임신 26-28주에 발생시는 234시간을 나타냈다. 전체 대상군에서 임상적 또는 조직학적 융모양막염의 발병률은 각각 10%와 72%를 보였다. 연구대상 중 태아사망은 없었으며 신생아 사망은 8명이었다. 주산기 생존율은 임신 20-25주에 조기 양막파열된 경우에서는 50%, 임신 26-28주군의 경우는 94%를 보였다. 결론 : 임신 2기 조기 양막파열에 있어서 관찰요법은 이제까지 알려져온 것 이상으로 주산기 생존율의 개선에 많은 도움을 줄 수 있을 것이다. Objective : The purpose of this study was to evaluate the perinatal outcomes in pregnancies complicated by preterm premature rupture of membranes (PROM) during the second trimester. Methods : Thirty-two consecutive pregnancies with PROM at 20-28 weeks of gestation were studied retrospectively. The goals of management were to prolong the pregnancies to 32 weeks through active expectant management and to avoid fetal compromise through close monitoring and active intervention. All medical records of mothers and neonates were reviewed. Results : Total 30 pregnant women with rupture of membranes at 20-28 weeks were included. Rupture of membranes occurred at 20-25 weeks(mean 24.2) in 14 women and at 26-28 weeks(mean 27.2) in 16 women. The median latency periods to delivery were 309 hours and 234 hours when rupture of membranes occurred at 20-25 weeks and at 26-28 weeks, respectively. Overall incidences of clinical and histologic chorioamnionitis were 10% and 72%. There were no fetal deaths and 8 neontal deaths. When rupture of membranes occurred at 20-25 weeks and at 26-28 weeks, the perinatal survival rates were 50% and 94%, respectively. Conclusion : Active expectant management of second-trimester PROM offers better perinatal survival than previously thought.
조백기,박종갑,김형옥,김성욱,백승철,김진우,김시용,안규중,전재복,오지원,김낙인,이규석,오칠환,김수남,김상태,손숙자,신용우,김동석,이원우,권경술,서대헌,황규왕,이종석,고재경,강원형,정기양,최응호,김기홍,박석돈,강승주,함정희,명기범,김방순,구상완,김병수,원영호,김한욱,송은섭,정병수,노병인,홍창권,박장규,한지윤,김광중,구대원,김종민,김재홍,유희준,양경미 대한의진균학회 1998 대한의진균학회지 Vol.3 No.2
Background: Onychomycosis, especially toenail onychomycosis has become one of the common fungal infection and has historically been regarded as a cosmetic rather than medical problem by many patients, even by physicians. Recently, however, there are several reports that is a refractory disease which may cause a deleterious effect on patiets quality of life (QOL). Objective: The purpose of this study was to investigate the impact of toenail onychomycosis on QOL in Korea and to assess the chandes of QOL after treatment. Methods: Total 1004 patients with toenail onychomycosis which was confirmed by clinical findings and KOH preparation were were enrolled at 47 dermatologic centers in Korea, and interviewed with standardized QOL questionnaire before and after sytemic antifungal treatment. Responses to the questionnaire were scored by 5-point scale (1∼4) and averaged, and were analyzed for 5 dimensions of emotional impact, social impact, symptorn and functional impact, patients views concerning treatment, and relationship with doctor. Results: 1. Before and after treatment, the most serious impact was emotional dimension showing 1.90 and 1.30 in average score (AS), and social (AS: 1.14 and 0.83) and symptom and functional impact (AS: 1.05 and 0.92) was also affected. 2. In female rather than male, statistically more significant impact on patients QOL was observed in all dimensions. 3. After treatment, 3 of 5 dimensions were improved significantly - emotional dimension (AS : from 1.90 to 1.30), social dimension (AS: from 1.14 to 0.83), patients view concerning treatment (AS: from 1.34 to 1.02). 4. The drgree of patients satisfaction at the therapeutic effect was very high- 62.4% (immediately after treatment) and 65.8% (9 months affer initiation of treatment) of patients answered excellent or good. Conclusion: This study confirms that toenail onychomycosis has significant impact on the overall QOL of patients. Also the effect of antifungal therapy on patients QOL were watisfactory. Therefore, both doctor and patient should pay more attention to the treatment of onychomycosis. [Kor J Med Mycol 3(1): 115∼124]
Case Reports : A Case of Zoster Duplex Bilateralis
Dae Hyun Kim,Kyu Uang Whang,Jong Suk Lee,Young Lip Park,Moon Kyun Cho,Sang Hoon Lee,Sung Yul Lee,Jung Woong Shin 대한피부과학회 2009 Annals of Dermatology Vol.21 No.4
The skin lesions of herpes zoster are classically limited to a single dermatome and most cases of multidermatomal herpes zoster have contiguous skin lesions. Simultaneous involvement of two noncontiguous dermatomes is very rare and it has been referred to as zoster duplex unilateralis or bilateralis, depending whether one or both halves of the body are involved. A 67-year-old woman presented with a group of painful vesicles on the right buttock and thigh, and left anterior chest and back. The Tzanck smear and skin biopsy were consistent with a herpetic infection. We report a rare case of zoster duplex bilateralis. (Ann Dermatol 21(4) 423~425, 2009)