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      • KCI등재

        자기폭로의 의미

        신아현(Shin, Ah-Hyun) 한국어문학회 2015 語文學 Vol.0 No.127

        The purpose of this dissertation is to reveal the aspect of Son Chang-seob’s Shin-ui-hui-jak as an autobiographical novel. Shin-ui-hui-jak has been used as a primary reference which must be dealt with in the study of Son Chang-seob’s litulature. Previous studies showed a tendency to treat the main character and the author Son Chang-seob presented in this work by the same person and extract the shape of a real artist from the main character’s abnormal personality and shocking experience. However, this study noted the writer consciousness that produced the controversial work Shin-ui-hui-jak, not like previous studies that eventually converge into psychoanalytical methodology. This study tried to purpose a new critical view under the premise that Shin-ui-hui-jak is also a fiction just like other stories. Shin-ui-hui-jak shows it’s character as an autobiographical novel from the introduction. If the autobiographical novel can be defined as a kind of confession, the confessional narration on the story exposes ugly and freakery shape of ego plainly which is distinct from usual confessions. The main character proves that the authority of society and system is nothing more than an illusion by his own existence as a ‘Superflous man’. He is portrayed as a person who has no will to enter the society. Son Chang-seob damages the authority of literature, literaty world and social position of writer by naming it’s character his real name. The narrator in the story plainly expose the other than self. In this process, the narrator, that is Narrating-I takes the subject of telling position which can realize and expose his ugly shape. He never be ashamed or penitent while he confesses the fault and unusualness of Narrated-I. His confession rather takes attitude of show-offish exposure, and attacks the inherent deception under the reader and social community which is presupposed to be listening the confession.

      • 암치료에 있어서 체질과 항암효과에 관한 한의학적 연구

        성현제,신현규,박갑주,강봉주,은영아,김은해,정세영 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

        As one of the chemical and experimental study on cancer treatment in Korea oriental medical hospital. Furthermore, we carried out the cytotoxicity test of extracts of herbal medicine. The results are as follows : About Clinical Aspects of the Oriental Medical Cancer Treatment - (1) Clinical experience is that 420 Oriental medical hospital were surveyed. Number of cancer patient treated by one oriental medical doctor was under 10(about 60%) or from 10 to 20(about 30%). (2) Diagnostic Procedure is that more than 80% of cancer patients were diagnosed by medical doctor of western hospital. (3) Therapeutic Method is that combination of oriental and western medical treatment was used in oriental medical hospital. (4) Relationship between cancer and constitutions is that to the relationship between cancer and constitutions, about 75% responded and most were considered to be Um. About Experimental Study - to evaluate the direct cytotoxicity of hot water and methanol extracts of 34 oriental medical presciptions on stomach cancer cell, SRB assay was carried out. (1) The IC50 value of water extract of Samsoum was 19㎍/㎖ and that of methanol extract was 15㎍/㎖, so that we confirmed Samsoum has a strong direct cytotoxicity. (2) The IC50 values of water extract of Coptidis Rhizoma, methanol extract of Caesalpiniae Lignum and Draba Semen were 10㎍/㎖, 19㎍/㎖ and 12.5㎍/㎖ respectively, so that we confirmed Coptidis Rhizoma, Caesalpiniae Lignum and Draba Semen have a strong direct cytototoxicity. (3) The IC50 value of combinatory prescription of Rhei Rhizoma, Forsythie Fructus and Caesalpiniae Lignum was about 40㎍/㎖.

      • KCI등재후보

        사업체 급식의 HACCP 제도 도입을 위한 인지도 조사

        이헌옥,심재영,신현아,정덕화,엄애선 한국조리과학회 2002 한국식품조리과학회지 Vol.18 No.3

        For the introduction of HACCP to industry food service, a survey was conducted from 150 dieticians and 40 managers on their recognition on HACCP system. The questionnaire of the survey included the status of current food safety management, management responsibilities, recognition on HACCP, problems in HACCP introduction. The majority of respondents was satisfied with the current food safety management, and the food service managers were more confident than dieticians in terms of food safety. Foodservice managers (100%) and dieticians (96%) recognized HACCP system; however, they responded the application of HACCP to industry food service were only 27% and 12.5%, respectively. They pointed out the reasons that they cannot introduce HACCP to their industry food service were the lack of benefits and good facilities. Dieticians strongly recognized the need of correction of food safety management in industry food service, compared with food service managers. The results suggest that the introduction of HACCP to industry food service should be accomplished by continuous education and information on food safety, improving facilities and a variety of benefits to HACCP-implemented companies from the government.

      • KCI등재후보

        서울시내 고등학교 위탁급식의 급식비와 투자비의 실태 및 위탁업체의 기대수준 비교 분석

        양일선,배환미,김현아,신서영,조미나,박수연,차진아,이보숙 한국식생활문화학회 2002 韓國食生活文化學會誌 Vol.17 No.5

        The purposes of this study were to a) find out the operational characteristics of the contract-managed highschool foodservice in Seoul, b) investigate the expected level of meal-price and facilities investment cost perceived by contract-managed highschool foodservice managers c) compare the present level and expected level of meal-price and facilities investment cost. From October 12 to November 13 in 2001, the questionnaires were mailed to 249 high schools which was managed by contract foodservice company with respondent rate 40.2%. Data were analyzed using SPSS Win(10.0) for descriptive analysis and one group paired t-test. The results of this study were as follows ; 1. The student enrollment of highschools run by contract-managed foodservice was 1,243 with 72.6% participation rate of school lunch program. The average meal-price was 2,138 won. The average annual period of school foodservice operation was 156.78 days per year. The average contracting period was about 3 years. 2. The average cost concerned in the facilities investment amounts 169,578,180 won at the initial investment and 25,204,092 won at the repairs and maintenance cost in the course of operation. 3. The present level of meal-price and facilities investment cost were respectively 2,136won/meal and 171,157,336.72 won. And expected level.of meal-price and amount of facilities investment cost were 2,418.75 won and 121,353,215.19 won. Comparing the present level with expected level of the meal-price and facilities investment cost, expected level of meal-price was significantly higher than the present level of meal-price(p<.001) and expected level of facilities investment cost was significantly lower than present level of facilities investment cost(p<.001).

      • KCI등재후보

        RAW 264.7 세포에 대한 중국산 천연 광물성 섬유 TAFMAG의 독성효과

        임영,한진구,김지홍,김현욱,김은경,김경아,장황신 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.3

        Objectives : This study was designed to evaluate cytotoxicity of TAFMAG, which is a trade name of natural mineral fiber mined and produced in China. Methods : The cytotoxicity of TAFMAG was evaluated by measuring iron content, lipid peroxidation, erythrocyte hemolysis, and cytotoxicity in vitro. These results were compared with the data of chrystotile and wollastonite as a positive and negative control, respectively. Results : There was significant increase of Fenton activity in TAFMAG and chrysotile with dose-response pattern. The iron chelating agent, desferrioxamine, significantly decreased Fenton activity of the particulates except wollastonite. TAFMAG and chrysotile fibers significantly increased malondialdehyde concentration from lipid peroxidation of the red blood cell membrane. In erythrocyte hemolysis test, TAFMAG & chrysotile had stronger effect on erythrocyte hemolysis than wollastonite with the concentration of 1,000g/ml. Furthermore, TAFMAG was more hemolytic than chrysotile with the concentration of 5,000g/ml. There was a significant cytotoxic effect in TAFMAG and chrysotile on RAW cell compared with wollastonite. Conclusions : In vitro study suggested that TAFMAG may have a similar health hazard as usual asbestos.

      • Functional Cardiomyocytes Formation Derived from Mouse Embryonic Stem Cells

        Shin Hyun-Ah,Lee Keum-Sil,Cho Hwang-Yoon,Park Sae-Young,Kim Eun-Young,Lee Young-Jae,Park Se-Pill,Lim Jin-Ho 한국발생생물학회 2003 한국발생생물학회 학술발표대회 Vol.2003 No.1

        Pluripotent embryonic stem (ES) cells differentiate spontaneously into beating cardiomyocytes via embryo-like aggregates. We describe the use of mouse embryonic stem (mES03) cells as a reproducible differentiation system for cardiomyocyte. To induce cardiomyocytic differentiation, mES03 cells were dissociated and allowed to aggregate (EB formation) at the presence of 0 75% dimethyl sulfoxide (DMSO) for 4 days and then another 4 days without DMSO (4+/4-). Thus treated EBs were plated onto gelatin-coated dish for differentiation. Spontaneously contracting colonies which appeared in approximately 4-5 days upon differentiation. Expression of cardiac-specific genes were determined by RT-PCR. Rebust expression of myosin light chain (MLC-2V), cardiac myosin heavy chain , cardiac muscle heavy polypeptide 7 -MHC), cardiac transcription factor GATA4 and skeletal muscle-specific -subunit of the L-type calcium channel () were detected as early as 8 days after EB formation, but message of cardiac muscle-specific -subunit of the L-type calcium channel (CaCh) were revealed at a low level. Strikingly, the expression of atrial natriuretic factor (ANF) was not detected. When spontaneous contracting cell masses were examined their electrophysiological features by patch-clamp technique, it showed ventricle-like action potential 17 days after the EB formation. This study indicates that mES03 cell-derived cardiomyocytes displayed biochemical and electrophysiological properties of cardiomyocytes and DMSO enhanced development of cardiomyocytes in 4+/4- method.

      • Subacute toxicity study of combined vaccine (KGCC-95Ⅵ) against Japanese encephalitis and Hantaan virus infection in mice

        Shin, Kwang-soon,Cho, Sung-hwan,Kim, Chul-joong,Shin, Hyun-jin,Nam, Sang-min,Park, Young-mi,Choi, Eun-ah,Kim, Eun,Yoon, Won-kee,Sohn, Hwa-young,Song, Dong-ho,Shin, Hyeong-soon,Ahn, Chang-nam 충남대학교 수의과대학 동물의과학연구소 1996 動物醫科學硏究誌 Vol.4 No.-

        최근에 (주) 녹십자가 개발한 일본뇌염 및 신증후 출혈열을 동시에 예방할 수 있는 혼합 백신(KGCC-95VI)의 아급성 독성을 조사하였다. ICR 마우스의 피하에 10, 50 및 250㎖/Kg(사람의 임상투여량의 20, 100 및 500배에 해당)의 KGCC-95VI를 매일 1회씩 30일간 투여하면서 임상증상을 관찰하였다. 시험기간동안 폐사한 동물을 없었고 KGCC-95VI에 의한 것으로 생각되는 임상증상도 없었다. 30일간의 투여후에 요검사, 혈액학적 검사, 혈액 화학적 검사 및 병리학적 검사를 실시한 결과 대조군과 비교할 때 아무런 이상이 확인되지 않았다. 따라서 KGCC-95VI는 마우스에서 아급성 독성을 갖고 있지 않는 것으로 생각된다.

      • SCIEKCI등재

        Dyspnea and Palpitation during Pregnancy

        (Hyun Suk Choi),(Seung Suk Han),(Hyun Ah Choi),(Hae Sung Kim),(Chan Guk Lee),(Youn Yee Kim),(Ji Ju Hwang),(Jeong Bae Park),(Hyun Ho Shin) 대한내과학회 2001 The Korean Journal of Internal Medicine Vol.16 No.4

        N/A Objectives: Dyspnea and palpitation are common features of pregnancy. While several theories have been put forward to explain the etiology of gestational dyspnea and palpitation, there have been few systemic studies of its incidence, severity and time-course in a group of normal women. Methods: We interviewed postpartum women, within 3 days after delivery, about dyspnea and palpitation. Separately from this interview, we performed 24-hour ECG monitoring for obstetric patients with palpitation before delivery. Results: The subjects interviewed were 261 women, of whom 37.5 percent and 11.5 percent experienced dyspnea and palpitation, respectively. These symptoms had a tendency to increase to term. The presence of arrhythmias could be documented in only 22% of patients having 24-hour Holter monitoring. Conclusion: Dyspnea and palpitation were common among normal pregnant women and had a tendency to increase to term.

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