하악골에 발생한 골막 골육종

김태우,김승범,권혁찬,문선재,윤정훈,김형준,차인호,육종인,김진 대한악안면성형재건외과학회 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.1

Periosteal osteosarcoma is a distinct entity of malignant bone tumor with characteristic clinical, morphological, and histological features within the group of juxtacortical osteosarcoma. Periosteal osteosarcoma is predominantly located in the tubular long bones, and extremely rarely involving the jaws. A case of periosteal osteosarcoma of the right mandible is presented. A 27-year-old woman complained of the gingival swelling and bleeding tendency of the right posterior mandible. Clinical examination revealed a reddish brown strawberry-like swelling on the affected mucosa, which measured 1.5㎝×1.5㎝. The tumor was located on the lingual cortex of the mandible and extended into the surrounding soft tissues. Microscopically, the tumor consisted exclusively of atypical chondroblastic cells with a small osteoblastic area. A minimal bone marrow involvement was noted and the adjacent cortex was free of tumor. These findings suggested that the tumor originated from the periosteal cambium layer, which lies between the periosteal fibrous layer and the cortex of mandible.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

老齡者의 建康을 위한 生活習慣 實態調査

申東敏,長鳳愚,李揆文,金賢俊,金昌範,崔宗洙,崔鍾晥,李鍾珏,金圭碩,趙庚旭,金鍾聲,朴鍾振 平生體育硏究所 論文集 1987 平生體育硏究所 論文集 Vol.2 No.-

With a view to examining the habit and method in which old people maintain and improve their health, we consulted 551 men and 444 women who were over 65 years old, and concluded as follows: 1. Habit of eating It's been revealed that most of the old people keep a regular eating hour, control the quantity of meal or eat a little food, and prefer vegetables to meat. 2. Mental health Old people feel the necessity for mental health and most of them (about 80%) keep good mental health without becoming pessimistic. Their chief concenrs have turned out to be about their sons and daughters and their own health and finance. 3. Managing Good Health It has been revelaed that old people do not possess any special kind of secret to keep good health but taking plenty of rest, regular meal, and proper exercise, and many of them (about 60%) have been shown to eat invigorant food that they can easily get around their living area. 4. Physical Functions It has been revealed that many old people are conscious of some symptoms about their parts of body and about to percent of them suffers from neuralgia. Some measures like medical aid especially for old people need to be taken as soon as possible. As we have found that the health-keeping method of old people consists plenty of rest, proper exercise, and appropriate nutrition, we can conclude that the recreatonal and culture facilities and programs for keeping old people in good health should be developed. It is also necessary to study food that contribute to their health and develop ways to get rid of the stresses to which they are exposed in their daily life. Presides, it is natural that government found an administrative department to deal with these matters effectively.

한의진단명과 진단요건의 표준화 연구 III : 3차년도 연구결과 보고

최선미,양기상,최승훈,박경모,박종현,심범상,김성우,노석선,이인선,정진홍,이진용,김달래,임형호,김윤범,박성식,송태원,김종우,이승기,최윤정,신순식 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analyzing and differentiating of epidemic febrile disease - analyzing and differentiating in accordance with the Sasang constitution medicine based on four-type recognition - differentiation of disease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance (-muscle. born, joint, etc.) - standards for diagnosis of neuropsychiatric disease - standards for diagnosis of five sense organ disease - standards for diagnosis of external disease The indivisual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattern, prognosis, a way of curing a disease, prescription, herbs in common use, disease appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirements in the following order : another name, notion of disease, the main point of diagnosis, analyzing and differentiating of disease, analysis of disease, discrimination of disease, prognosis, a way of curing and prescription of disease, disease in western medicine appearing the disease in oriental medicine, documents.

步行에 關한 文獻的 考察

김범철,금동호,이명종 동국대학교 한의학연구소 1996 東國韓醫學硏究所論文集 Vol.5 No.-

When we see normal gait, gait cycle is seperated as stance phase and swing phase. It needs 6 determinant of gait of pelvic rotation, pelvic tilt, knee joint of stance phase, ankle and foot motion, ankle and knee motion, and pelvic movement to be accomplished. In addition a joint and muscle action is accomplished biomechanically at the same time with its gait cycle. In oriental medicine, the relationship between chang-fu physiology and meridian physiology are summaried as follows : · chang-fu physiology : Spleen manages the extremities Liver manages sod tissues. Liver stores blood. Kidney stores essences. Kidney manages bones. · meridian physiology : The Leg Greater Yang Meridian and meridian soft tissues The Leg Yang-Myeong Meridian and meridian soft tissues The Leg Lesser Yang Meridian and meridian soft tissues The Leg Greater Yin Meridian and meridian soft tissues The Leg Lesser Yin Meridian and meridian soft tissues The Leg Absolute Yin Meridian and meridian soft tissues Especially, we can find out relation between in a "blood supplied feet can walk well" that explains "blood regulations and by liver nourishing affects"that is the closest concept of muscle. Abnormal gaits are due to three causes as following: first, physical defect second, pain third, nervous system or instability of muscle. In oriental medicine, we can know relationship in "atrophy, numbness, stroke, convulsion, muscular dystrophy of knee, rheumatoid arthritis, five causes of infantile growing defects, five causes of softening, sprain". Especially, atrophy is the most important symptom. Gait evaluation should be emphasized where a point can walk 8 feet to 10 feet considering stride width, stride length, the body weight center, stride number, flexion, extension, rotation of a joint as a standard factor. The point is we should find out something strange in a patient's side, front and back view. After that we should find out its cause as an index that we can observe abnormal findings in a joint and muscle.

정신분열병 환자의 뇌저신경절의 자기공명영상 소견

김종범,이길홍,나철 大韓神經精神醫學會 1995 신경정신의학 Vol.34 No.4

This study was performed to investigate possible neuroanatomical changes in the basal ganglia of schizophrenic patients. We used magnetic resonance imaging morphometric techniques, selected of two axial planes to show obviously basal ganglia, to estimate the area and the volume of specific nuclei of basal ganglia and cerebral hemispheres and further each precentage by the same hemisphere in schizophrenic patients and controls with mild neurotic complains, who had no significant difference in age- and sex- distributions. Schizophrenic group had greater basal ganglia in all nuclei analysed : these differences didn't attain statistical significance for all. Estimates of the area and each percentage of all nuclei of basal ganglia execept globus pallidus in the lower slice, not the higher slice were increased. Estimates of the volume of putamen, lenticular nucleus, striatum in all nuclei of basal ganglia were increased in the schizophrenic patients. The area increase in all nuclei of basal ganglia except globus pallidus and especially the volume increase in putamen, lenticular nucleus, and striatum are cautiously interpreted as one of the evidences supporting neurodevelopmental hypothesis of the pathogenesis of schizophrenia.

운동특성에 따른 체구성과 골조성의 비교

김창범,박종진 충북대학교 평생체육연구소 2000 平生體育硏究所 論文集 Vol.12 No.-

This study was to analyze the body and bone compositions according to exercise characteristics. 32 subjects attending universities consisted of 8 track players, 8 tennis players, 8 wrestling players, and male students. A whole body scanner (model:dual X-ray absorptiometry, LUNA) was used to measure body composition components, bone mineral content, total bone calcium, bone mineral density, Comparisons of each group's bone densitometry numerics revealed following results. First, %body fat and fat body weight were significantly lower in track players, while lean body weight was significantly higher in wrestling and track players. Second, bone mineral content was significantly higher in wrestling players arms and body and track players' leg. Third, total bone calcium was significantly higher in wrestling players. Fourth, bone mineral density was significantly higher in track, wrestling and tennis players' pelvis and wrestling players' all the other parts. In sum, endurance training like track play had positive effects on developing appropriate body composition, while wrestling characterized by heavy weight, excessive and continuous exercise, and high loading had positive effects on developing appropriate bone composition. Hence, endurance training involving high loading and dynamics would be effective sports for developing appropriate body compositions.

전리수에서의 STS304의 부식

이종권,박소연,김범식 순천향대학교 산업기술연구소 2006 순천향 산업기술연구소논문집 Vol.12 No.1

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成人 排球選手들의 Sports 傷害에 關한 硏究

金昌範,金顯俊,朴鍾振 忠北大學校 平生體育硏究所 1991 平生體育硏究所 論文集 Vol.5 No.-

After I investgated the matters about the sprots injuries of the one hundred and twenty-nine men and women volleyball players who belonged to a business volleyball league and played in the volleyball game of President Cup in 1992, I got the following results. 1. It was found that many player suffered from sports injuries between one and three years after they began the sport, the time when the injuries happened was the middle of the main sport, and the season when the injuries happened is almost winter. 2. It was found that the most state when the injuries happened was in the middle of exericise, the part of body where the injuries happened was mainly hand or ankle, and when the injuries happened, the used sport technique was mainly when the player made a blocking, trained their bodies, made a landing , and so on. 3. It was found that the first aid which was needed when the sport injuries happened was mainly given by the coach, director, or colleague, and after the first aid the players were treated at the hospital or went to the herb doctor. 4. It was found that the length of the time when the players could not take part in the game was mainly below a month and after about seventy of eighty percent recovery, they took part in the game again. 5. It was found that the main causes of injuries accurrences were the carelessness of the players', the lack of warming-up, and so on, and the ways by which injuries could be reduced were the cultivation of the power of concentration and mental power, and the sufficient warming-up.

封着유리와 스테인레스鋼의 接合에 關한 硏究

金宗範,金鳳杰,朴慶煥 慶熙大學校 1987 論文集 Vol.16 No.-

Effects of a metal-to-glass joints for the solder glass of lead-zinc-borate system, on the temperature of wettness, crystallization, adhesive properties and microstructures when a metal was jointed with the solder glass, were studied. There are three critical parameters required for these pints, mechanical strength to withstand strain, viscous behavior of the frit and the lowering of process temperature. So this study includes adherent strength test, wetting test, crystallization test, etc. For the experiments, AISI No. 304 stainless steel as base and solder glass as bonding material were used. Results were as follows. The lowest crystallization temperature was 440℃ and the maximum adherent strength was 21.3_f/㎠.