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      • KCI등재

        절박유산과 정상임부 및 시험관아기시술 환자에서 초기임신인자의 임상적 유용성

        이진용,문신용,김정구,배광범 대한산부인과학회 1997 Obstetrics & Gynecology Science Vol.40 No.6

        Early pregnancy factor(EPF) is believed to be a pregnancy-associated immunosuppressive polypeptide which might inhibit the function of maternal lymphocyte during pregnancy. The physiological role of EPF in human pregnancy has remained controversal. The purposes of this study are to investigate whether EPF determinations have prognostic value in women with threatened abortion, and to evaluate usefulness in diagnosing early pregnancy and in predicting the outcome of embryo transferred in vitro fertilization-embryo transfer(IVF-ET) program. EPF activity was measured by a recently developed, micro rosette inhibition test in sera from 76 normal pregnant women, 25 normal healthy women with tubal ligation, 58 women with therapeutic surgical abortion(n=18) or threatened abortion(n=40) and 29 IVF-ET patients. Rosette inhibition titer≥3 was defined as an index for the presence of EPF activity. EPF activity was undetectable in sera of normal healthy women with tubal ligation and in sera taken before ET. In normal pregnancy EPF was detected in 88~92% of sera during the first and second trimester and almost disappeared in the third trimester. Surgical therapeutic abortion in the first trimester lead to disappearance of EPF activity in 92.3% of cases second day after procedure. The sensitivity of the EPF assay in predicting the outcome in pregnant women with threatened abortion was 88.0% and the specificity was found to be 86.7%. In patients who became pregnant after IVF-ET procedure EPF activity was detected in 85.7% of sera on the 5th day and in all sera on the 12th day. In 80.0%(9/13) sera of patients who failed to become pregnant after ET, EPT activity was detected on the 5th day but 17(94.4%) of 18 sera was proved to be negative for EPF activity on the 12th day. These data suggest that EPF assay by micro rosette inhibition test may be useful in monitoring the embryo after ET, in dignosing early pregnancy and in predicting the outcome in women with threatened abortion.

      • KCI등재

        경주 국가지하수관측소 일자료로 본 경주지진 영향

        이진용,Lee, Jin-Yong 한국지하수토양환경학회 2016 지하수토양환경 Vol.21 No.6

        Earthquakes of M5.1, M5.8 and M4.5 occurred in September 12 and 19 respectively in Gyeongju, Gyeongbuk Province. Theses earthquakes inflated fears of people and highlighted necessity of detailed countermeasures because we have considered our country is safe to earthquakes. In the meanwhile, earthquake also impacts groundwater and thus it was recently reported that the Gyeongju Earthquakes affected groundwater there. This study evaluates daily groundwater data collected from five national groundwater monitoring stations (Geoncheon, Sannae, Oedong, Yangbuksin, Cheonbuk) in Gyeongju. The analysis revealed that only groundwater level of bedrock monitoring well hosted in andesite exhibited earthquake impact while no wells in the other four stations hosted in sedimentary rocks showed substantial responses to the earthquakes. This may be derived from the difference of seismic velocity of hosting rocks as well as epicenter distance. Special interest on groundwater monitoring is required to predict earthquakes as precursory phenomena.

      • KCI등재

        습관성유산 환자에서의 면역글로블린의 치료효과

        이진용,장윤석,문신용,김정구,신창재,고창원 대한산부인과학회 1994 Obstetrics & Gynecology Science Vol.37 No.10

        서울대학교병원을 방문한 원발성 습관성유산 환자로서, 기존의 알려진 원인이 제거된 원인불명의 습관성유산 환자중 임신이 확인된 환자 5명을 대상으로 하여, 면역글로불린을 약 2주간격으로 투여하여 다음과 같은 결과를 얻었다. 1. 과거력상 총 16예의 습관성 유산력이 있는 환자 5명에서 면역글로불린으로 치료하여, 5예의 임신이 만삭까지 지속되었다. 2. 대상환자 5명중 4명에서 질식분만, 1명에서 제왕절개 시술로 생존 태아를 분만하였다. 3. 약물에 대한 부작용은 5예에서 전혀 관찰되지 않았다. 이상의 기초적 자료들은 원발성 습관성 유산 환자에서 면역 글로불린 치료가 임신유지에 효과가 있다는 것을 제시하는 소견이라 할 수 있으나, 향후 더 많은 환자를 대상으로 한 전향적이고 대조군이 있는 연구가 필요하다고 사료된다. Intravenous immunoglobulin(IVIG) treatment was attempted as a therapeutic approach in five women with unexplained primary habitual abortion. Therapy was commenced at the time of diagnosis of pregnancy with 10 gm of IVIG. Infusion was done every other weeks and terminated at 2 weeks after the time of previous abortion. All five patients delivered living infants at term. One of them was delivered by cesarean section because of fetal distress, and remainders were vaginally delivered without problem. There was no adverse effect of IVIG. These preliminary data may suggest that IVIG may be applicable to patients with primary habitual abortion.

      • KCI등재

        장애인의 의료기관 접근성은 향상되었는가? - 서울시 종로구 병의원을 대상으로 -

        이진용,정재영,김유경,전은경,김소윤,김현주,이보우 한국보건행정학회 2012 보건행정학회지 Vol.22 No.4

        The purpose of this study was to evaluate the improvement of disabled access to healthcare institution located in Jongno-gu, Seoul in 2011 compared to 2003 since disabled access has been mandatory in healthcare institutions located in new buildings by the amended law in 2004. We had investigated 10 assessment items for disabled access in 166 healthcare institutions located in Jongno-gu, Seoul and the results were compared with those of 2003 survey. On average, 74.1% of the healthcare organizations has equipped with items for disabled access. However the adequately equipped rate for those items was only 39.2%. Compared with the results of 2003 survey, these rates showed a little increase by 4.1% and 8.0%, respectively. There were only 10 healthcare institutions located in new buildings which were constructed after July, 2005. Their average equipped rate(84.4%) and adequately equipped rate(46.8%) were higher than those of the other organizations because the Korean government ruled that healthcare institutions in new buildings must have facilities for the disabled. In conclusion, we confirmed that the accessibility of the disabled to healthcare institution slightly increased. In particular, the healthcare institutions in newly constructed building showed the significant increase of accessibility of the disabled. However, it is founded that disabled access is still not enough for the disabled.

      • KCI등재

        개인의 정치성향이 친사회적 행동에 미치는 영향 - 메시지프레이밍과 심리적 거리를 중심으로

        이진용,이유나,정윤재 한국소비자·광고심리학회 2015 한국심리학회지 소비자·광고 Vol.16 No.3

        This research examines how political ideology affects prosocial behavior. Especially. we focus on the interaction of political ideology and message framing, and also the interplay of political ideology and perceived psychological distance on target recipients. This study has a 2 (political ideology: liberal vs. conservative) x 2 (message framing: gain vs. loss) x 2 (psychological distance: near vs. far) design, Both the amounts willing to donate (study 1) and the amounts willing to invest (study 2) point out that the liberals are more sensitive to gain whereas the conservatives are more sensitive to loss. The interaction effect of political ideology and psychological distance is also significant. Whereas liberals intend to help (or invest for) the psychologically near and distant target groups equivalently, conservatives are more likely to donate to (or invest for) the psychologically near group than the psychologically distant group. This article concludes by discussing the theoretical implications of our findings for political ideology, message framing, and psychological distance and by suggesting practical implications. 본 연구는 개인의 정치성향이 친사회적 행동에 미치는 영향을 메시지프레이밍과 대상과의 심리적 거리를 중심으로 살펴보고자 하였다. 친사회적 행동 영역을 개인영역인 기부활동과 사회적 시스템 구축에 대한 의사결정으로 구분하여 총 두 번의 실험을 실시하였다. 실험 1은 개인영역의 대표적인 친사회적 행동인 기부영역에서 개인의 정치성향, 메시지프레이밍(이득 혹은 손실), 기부자-수혜자간 심리적 거리(국내 혹은 국외 수혜자)에 따른 결식아동에 대한 기부금액 차이를 살펴보았다. 실험결과, 개인 정치성향과 메시지프레이밍 상호작용 효과가 나타났다. 구체적으로 진보성향 사람들은 이득메시지가 제시되었을 때 손실메시지가 제시될 때에 비하여 기부금액이 더 높게 나타났다. 이와 반대로 보수성향 사람들은 이득메시지에 비하여 손실메시지가 제시될 때 기부금액이 더 높게 나타났다. 정치성향과 기부자-수혜자간 심리적 거리에 따른 상호작용이 나타났다. 진보성향 사람들은 심리적 거리감에 따른 기부금액 차이가 나타나지 않아 국내 및 국외 수혜자에 대하여 비슷한 수준의 기부의향을 보였으나, 보수성향 사람들은 심리적 거리가 가까운 국내결식아동에 대해 심리적 거리가 먼 국외결식아동에 비하여 기부금액을 더 많이 후원하겠다고 하였다. 실험 2에서는 친사회적 시스템 구축 의사결정에 있어 개인의 정치성향, 메시지프레이밍, 수혜자와의 심리적 거리를 중심으로 살펴보았다. 연구결과 진보성향의 사람들은 이득메시지가 제시될 때, 보수성향의 사람들은 손실메시지가 제시되었을 때 사회적 시스템 구축에 대한 투자의향 금액이 더 높게 나타났다. 또한 실험 1과 동일하게 진보성향의 사람들은 국내 혹은 국외 친사회적 시스템 구축에 대한 투자의향 금액 차이가 나타나지 않았다. 이에 반해 보수성향의 사람들은 국내 친사회적 시스템 구축할 경우 국외 친사회적 시스템 구축에 비하여 투자금액이 더 높게 나타났다. 본 연구는 정치영역에서 주로 다루었던 개인의 정치성향을 공공마케팅 영역에서 살펴보았다는 것에 이론적 시사점이 있다. 실무적으로는 최근 비영리기관에서 다양한 마케팅 활동을 통하여 개인 기부활동을 촉진하고자 노력하는데 이에 대한 효과적인 커뮤니케이션 전략을 제공할 수 있을 것이다.

      • KCI등재

        우방자(牛蒡子)가 아토피 피부염에 미치는 영향

        이진용,김덕곤,한규철,Lee, Jin-Yong,Kim, Deog-Gon,Han, Kyu-Chul 대한한방소아과학회 2004 대한한방소아과학회지 Vol.18 No.2

        Objective : Atopic dermatitis has a close relationship with degranulation of mast cell and separation of Histamine. As there's no experiment with herb, using Arctii Fructus, we investigated experimental influence of Arctii Fructus on degranulation of mast cell and separation of histamine in SD rat. Methods : The SD rats are classified into three groups. One group is normal one treated by normal saline before medical treatment. The other is control group prescribed to Compound 48/80 before normal saline treatment. And the third is experimental group prescribed to compound 48/80 after medical treatment of Arctii Fructus. Then, I investigated the experimental results by measuring the degree of degranulation and separation of histamine. The results of investigation on SD rat group showing the degree of inhibitory effect of degranulation of a mast cell are as follow, the normal group treated by normal saline reflecting the degree of degranulation is $6.10{\pm}0.20\;%$, the control group treated by only compound 48/80 is $87.56{\pm}11.00\;%$, the experimental group which treated by compound 48/80 and Arctii Fructus's medical treatment is $16.26{\pm}4.67\;%$. Results : The normal group treated by only normal saline reflecting the degree of degranulation is $6.10{\pm}0.20\;%$, the control group treated by only compound 48/80 is 87.56=11.00 %, the experimental group treated by compound 48/80 and Arctii Fructus's medical treatment is $16.26{\pm}4.67\;%$. This result indicates that the degree of degranulation of mast cell is obviously inhibited (p<0.0l) in the experimental group in comparison with control one. The analysis of data obtained from plasma, which collected from the experimented SDrats' hearts before their death, and the measurement of quantity of histamine secretion show the following results. The quantity of normal group and control one is $25.34{\pm}4.58$ nM, $348.59{\pm}30.77$ nM respectively, and experimental one prescribed to compound 48/80 after medical treatment of Arctii Fructus is $263.56{\pm}21.34$ nM. This result indicates that separation of histamine isobviously inhibited in the experimental group in comparison with control one (p<0.05). Conclusions : Arctii Fructus does obviously inhibit the degree of degranulation of mast cell (p<0.0l) and separation of histamine in the plasma (p<0.05).

      • KCI등재

        단계양수시험 해석시 시간선택이 해석결과에 미치는 영향

        이진용,송성호,이강근,Lee Jin-Yong,Song Sung-Ho,Lee Kang-Kun 한국지하수토양환경학회 2005 지하수토양환경 Vol.10 No.2

        단공 수리시험으로서의 단계양수시험은 일반적으로 대수층 및 우물의 생산성 혹은 효율을 평가하기 위해 수행되어 왔다. 단계양수시험은 기본적으로 초기에 저양수량으로 양수를 하며 양수관정의 수위가 안정되면 다음 단계의 고양 수량으로 다시 수위가 안정될 때까지 양수를 지속한다. 이러한 과정은 최소 3단계 이상 반복되며 각 단계별 양수지속시간을 동일하여야 한다. 본 기술자료에서는 그 동안 국내에서 수행된 단계양수시험의 해석과 관련하여 몇 가지 문제점들을 살펴보았다. 그 결과 단계양수시험에 대한 부적절한 해석결과는 주로 잘못된 해석개념 및 불완전한 현장 양수자료와 관계가 큰 것으로 파악되었다. Step-drawdown test has been generally conducted to evaluate productivity or efficiency of both aquifer and well. In general step-drawdown test, pumping with a low constant discharge rate is conducted in the first stage until the drawdown within the well stabilizes. And then the groundwater is pumped with a higher rate in the next step until the drawdown stabilizes once more. This process is repeated at least three times (steps), with the equal duration. In this paper we tried to review some critical problems related to the step-drawdown test, which were revealed in the process of field practices and analyses. The problems, referred in this paper are mainly associated with the incorrect conceptual approach for analysis and incomplete data collection in the field test.

      • KCI등재

        전남 해안 LPG 저장공동 유출수와 주변 지하수의 수질특성

        이진용,최미정,김현중,조병욱,Lee, Jin-Yong,Choi, Mi-Jung,Kim, Hyun-Jung,Cho, Byung-Wook 한국지하수토양환경학회 2009 지하수토양환경 Vol.14 No.4

        LPG를 저장하는 지하공동의 수장막 시스템은 고압의 가스가 공동 밖으로 새어나가지 못하도록 원활한 지하수의 흐름과 안정적인 지하수두 유지가 필수적이다. 본 연구에서는 전남 여수 LPG공동의 유출수 및 주변 지하수의 수질특성을 파악하기 위하여 2007년 2월, 5월, 8월, 10월에 걸쳐 시료채취, 현장측정 및 실내 수질분석을 실시하였다. 현장 측정 결과 pH는 약산성에서 중성으로 나타났고 10월로 갈수록 증가하는 경향을 나타내었다. 전기전도도는 소금적치장과 인접한 관정의 경우 $10.47{\sim}38.50\;mS/cm$로 매우 높게 나타났다. 용존산소는 $0.20{\sim}8.74\;mg/L$로 매우 넓은 범위를 보였고, 산화환원전위는 평균 159 mV로 비교적 산화환경임을 나타냈다. 또 $Fe^{2+}$, $Mn^{2+}$의 농도는 대부분 3 mg/L 미만으로 나타났다. 수질유형은 유출수의 경우 4차례 모두 Na-Cl type로 나타났으나 지하수의 경우 소금적치장 인접 관측정은 Na-Cl type으로 높은 TDS를 보였다. 다른 지하수 관측정은 전형적인 $Ca-HCO_3$ type으로 나타났다. 미생물 분석결과 호기성세균의 수가 $573{\sim}39,520\;CFU/mL$로 비교적 높게 검출되었다. 본 연구에서 수리화학 및 미생물학적 특성을 분석한 결과 지하수와 유출수는 여수 저장공동의 운영에 있어서 큰 문제를 일으키지 않을 것으로 사료된다. 그러나 미생물 증식의 제어와 수리적 안정성을 유지하기 위해서는 지속적인 모니터링이 요구된다. Water curtain of an underground LPG storage cavern is a facility to prevent leakage of high pressure gases, for which groundwater should flow freely towards the cavern and groundwater level also must be stably maintained. In this study, in order to evaluate qualities of seepage water and surrounding groundwater of an underground LPG storage cavern in Yeosu, 4 rounds of samplings, field measurements and laboratory analyses (February, May, August, October of 2007) were conducted. According to field measurements, pH was weak acidic to neutral but it gradually increased with time. Electrical conductivity (EC) of groundwater near a salt stack showed very high values between 10.47 and 38.50 mS/cm. Dissolved oxygen (DO) showed a very wide range of 0.20~8.74 mg/L and a mean of oxidation-reduction potential (ORP) was 159 mV, which indicated an oxidized condition. Levels of $Fe^{2+}$ and $Mn^{2+}$ were mostly less than 3 mg/L. All of seepage waters showed a Na-Cl type while only groundwater near the salt stack showed a Na-Cl type with a high total dissolved solid. The other groundwaters exhibited typical $Ca-HCO_3$ types. Levels of aerobic bacteria were mostly very high (573-39,520 CFU/mL). Based on the analyses of these hydrochemistry and biological characteristics, it is concluded that there are no particular problems in groundwater and seepage water, which not causing a trouble in the cavern operation. However, both for control of bio-clogging and for sustainable operation of the water curtain system, a regular hydrochemical and microbiological monitoring is required for the seepage water and surrounding groundwater.

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