한국인 직무 스트레스 측정도구의 개발 및 표준화

장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

역해석을 이용한 압밀정수의 재평가

정진섭,최우정 원광대학교 대학원 2007 論文集 Vol.39 No.-

The purpose of this paper is to estimate settlement using the measurement data and to verify the application back-analysis by finite element analysis. It is very important to predict settlement in pre-loading method used to improve soft ground. But the settlement measured in the field shows a considerable difference from the predicted settlement due to various factors such as non-homogeneous soft layers, sampling disturbance, erroneous selection of soil parameters and deficiency of consolidation theories among others. Therefore, analysis of actual settlement behavior based on the measurement data during consolidation period is a very useful procedure in evaluating the rates of consolidation settlement. This study estimates settlement using analysis methods such as Hyperbolic, Hoshino and Asaoka method. Because these prediction method of ultimate primary settlement are analytically simple and economical, they are widely used in the field. To search consolidation parameter for site, back-analysis technique was performed using finite element analysis. From the results of analysis, the back-analysis technique for consolidation parameter is verified. Because a feed-back system to combine the data measured in construction field with priorly estimated information at the design stage is necessary.

좌심방에 발생한 원발성 미분류 방추세포 육종 1례

조정환,홍그루,송인욱,손창우,정선영,남종호,김미진 영남대학교 의과대학 2009 Yeungnam University Journal of Medicine Vol.26 No.2

Water glass로부터 ZSM-5의 합성

우훈희,홍지숙,서정권,이관영,이정민 한국공업화학회 2002 응용화학 Vol.6 No.2

In order to seek optimum conditions for ZSM-5 formation in the absence of organic template,the effects of both starting composition and water glass as silica source were examined. Water glass was most inexpensive among silica sources, but this was difficulty in reactant control because of contained much alkali ingredient, Considering environmental problem and economic performance,chose alkali drawing-out method to use methanol newly to remove alkali ingredient of waterglass. Characterization of ZSM-5 was carried out by means of XRD, SEM.

Bacillus sp. YJ-63이 생산하는 항곰팡이 항생물질의 구조분석

정영기,신영준,정명주,주우홍,최재수 Institute of Genetic Engineering Changwon National 2002 Gene and Protein Vol.6 No.-

토양으로부터 분리한 Bacillus sp. YJ-63으로부터 항진균성 항생물질을 분리하여 그 구조를 분석한 결과는 다음과 같다. 항생물질은 7개의 α-amino acid와 1개의 β-amino acid가 결합한 환상구조를 가지는 iturin E 계에 속하며 특히, β-amino acid의 methylene 수가 기존의 iturin E 보다 더 많은 것으로 나타났다. Structural analysis was performed by the ^1H-NMR, ^13C-NMR, amino acid composition analysis and FAB-mass. The instrumental analysis represented that the potential antifungal antibiotic belonged to the iturin E group antibiotic, consisting of 7 α-amino acid residues and a collection of β-amino acid with aliphatic side chain. Compared to the iturin E group, notably, the potent antifungal antibiotic from bacillus sp. YJ-63 carried longer β-amino acid side chain. In conclusion, these findings identified a potential antibiotic, which contained a stable cyclopeptide structure with long β-amino acid side chain.

후두 미세수술 후 발생한 일시적인 설인신경 및 설하신경 장애 1예

정철우,주영민,박성철,최정섭 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.11

뇌혈관질환을 동반한 당뇨병 환자에서 지속적 혈당측정의 유용성 평가

정성훈,강인구,박철영,류미숙,우정택,김성운,김진우,김영설 대한당뇨병학회 2002 임상당뇨병 Vol.3 No.2

연구배경: 뇌혈관질환을 동반한 고령의 당뇨병환자는 이들의 신경학적 결손으로 경고 증상없이 심한 저혈당에 노출될 가능성이 크다. 실제로 하루 4번 정도의 자가 혈당 측정으로는 이를 감지하기 어려울 뿐 아니라 검사에 따른 고통으로 적극적인 혈당 조절에 제한이 따르게 된다. 이에 저자들은 Mini Med사의 지속적 혈당측정기(CGMS, continuous glucose monitoring system)를 이용하여 뇌혈관질환을 동반한 당뇨병 환자에서 24시간 혈당의 변동양상을 알아보고 각기 다른 인슐린 치료방침에 따른 혈당조절의 효율성을 비교하고자 하였다. 방법: 2001년 1월부터 6월까지 경희대학교 부속병원에 입원해 있는 10명의 뇌혈관질환을 동반한 제 2형 당뇨병환자를 대상으로 하였다. 이 들은 모두 튜브식이를 받고 있엇고 최소 1개월 이상 인슐린 치료를 시행 받았다. 지속적 혈당측정기를 착용하고 3일간의 연속적인 혈당을 측정하였고, 치료 첫 날은 NPH, 둘째 날은 속효성 인슐린과 NPH, 마지막 날은 혼합형 인슐린제제로 치료하여 그 효과를 비교하였다. 이들 각기 다른 인슐린 제재의 하루 총량에 차이는 없었다. 혈당치가 3.3mmol/L 미만이거나 7.8mmol/L를 초과하는 경우 그 차이값의 총합을 시간으로 나누어 이 값(△Glu)이 적을수록 치료효과가 우수한 것으로 판정하였다. 또한 당 수치가 3.3mmol/L 미만인 경우를 저혈당 event, 16.7mmol/L 초과한 경우를 고혈당 event로 임의로 정의하였고, 이를 통해 지속적 혈당측정의 유용성을 간접적으로 평가하고자 하였다. 결과: 평균 △Glu값은 첫째 날이 0.93 ± 0.43mmol/Lㆍmin?¹, 둘째날이 0.71 ± 0.29mmol/Lㆍmin?¹ 마지막 날이 0.58 ± 0.29mmol/Lㆍmin?¹로서 서로 다른 3가지 치료방침사이에 통계학적으로 유의한 차이는 없었다(p=0.115). 10명의 환자들 중 자가 혈당측정기로는 1명에서 저혈당 event, 2명에서 고혈당 event를 인지하였으나 지속적 혈당측정기로는 각각 9명에서 event를 확인하였다. 결론: 지속적 혈당측정기를 이용한 각각의 인슐린 치료방침에 따른 혈당조절 효율성의 차이는 없었으나, 자가혈당 측정기로는 알 수 없었던 일 중 혈당 변동사항을 정확하게 알 수 있어, 뇌혈관질환을 동반한 당뇨병 환자에서 보다 적극적인 인슐린 치료 및 관리를 할 수 있을 것으로 생각된다. Background: Diabetic stroke patients are susceptible to hypoglycemia. However, there are many limitations in detecting hypoglycemic events, even though glucoses levels are checked 3 to 4 times per day using the fingerstick method. Therefore, we investigated the glycemic excursions and pattern in diabetic stroke patients using the continuous glucose monitoring system (CGMS, MiniMed) and its clinical utility. The other objective was to compare the treatment dfficacy between insulin regimens. Methods: From jan 2001 to jun 2001, 10 adult type 2 diabetic stroke patients wore CGMS for consecutive 3 days, which continuously checked the glucose level. NPH insulin, multiple daily injection of regular insulin ± NPH and the mixed type(Novolet 30/70, Novo Nordisk) were used on the first, second and third days of the study, respectively. If the mean delta glucose(△Glu = A+B/time, A=∑(hlucose-7.8), glucose > 7.8 mmol/l, B=∑(3.3-glucose) if, glucose < 3.3 mmol/l) was calculated in order to recognize the degree of individual glycemic changes and to compare the efficacy of each treatment diverse insulin regimen. We arbitrarily defined a glucose level less than 3.3mmol/l, as a hypoglycemic event, and more than 16.7mmol/l as a hyperglycemic event. Results: Variable patterns of glycemic changes were observed among patients with the same dosage, but a different insulin regimen. The mean △Glu was 0.93±0.43 on the first day, 0.71±0.29 on the second day and 0.58±0.29 on the third. There was no significant difference in treatment efficacy between the 3 different insulin modalities(p=0.115). Of the 10 patients, a hypoglycemic event was detected in 1 with the fingerstick method, in contrast to 9 with CGMS, with hyperglycemic events being detedted in 2 and 9, respectively. Conclusion: Continuous glucose monitoring maybe useful in providing the information necessary for optimal glycemic control in the diabetic stroke patients.

LC-MS/MS를 이용한 S.D. Rat 혈장 중 Arctiin 분석법 개발

송병정,채정우,백현문,권광일 충남대학교 약학대학 의약품개발연구소 2014 藥學論文集 Vol.29 No.-

KIOM-MA128 is a novel oriental herbal medicine which is for atopic dermatitis and asthma. The purpose of this study was to develop on analytical method of arctiin in rat plasma after oral administration of KIOM-MA128. Analyte was separated on a Atlantis dC18 reverse phase column, using gradient mobile phase (A:B = acetonitrile: 0.1% formic acid in water) at a flow rate of 0.3 mL/min. Detection was performed by electrospray positive ionization mass spectrometry using multiple reaction monitoring of the transitions of arctiin at m/z 552.4 → 372.8 and internal standard (carbamazepine) at m/z 237.0 → 194.5. The limit of quantification was 1 ng/mL for arctiin. The precisions were lower than 15% and the accuracy was between – 12.21 and 3.2%. The maximum concentration found in plasma samples was 4.1 ng/mL. The present method was successfully developed for detecting arctiin in plasma and this results would be utilized to the further study.

감마선 조사 랫트의 고환에서 fibronectin의 발현

정진우,김희철,김정태,안미정,이지영,신태균 제주대학교 방사능이용연구소 2005 방사선응용과학연구소논문집 Vol.19 No.-

교원의 노동조합 설립 및 운영 등에 관한 법률과 교원노조 활동에 대한 교원의 인식 연구

정회욱,송정우 木浦大學校 敎育硏究所 2004 교육연구 Vol.16/17 No.-

이 연구는 교원의 노동조합 설립 및 운영 등에 관한 법률과 교원노조 활동에 대한 교원의 인식 연구이다. 본 연구에 따르면, 다수의 교사들은 다음과 같이 인식하고 있다. 교원들의 쟁의행위 허용 주장은 「정상적인 업무를 저해하지 않는」 집단행동 허용을 원하고 있기 때문에 법리적으로는 노조법상 쟁의행위가 아닌 국가공무원법 또는 교육공무원법상 단체행동 허용을 의미한다. 교원노조법에 단체 교섭의 대상에 대한 명문의 규정이 없으므로 인사제도, 교육정책·교육과정에 관한 사항이라고 하더라도 교원의 고용과 밀접불가분의 관계가 있는 사항은 단체교섭의 대상이 되어야 한다. 교원노조의 단체협약은 조합원에게만 적용되는 것이 협약의 본래의 성격이나 사용자가 형평성의 원리에 입각하여 임의로 비조합원에게도 적용하기 때문에 교원노조는 단체협약 체결에서 전체교사의 의견을 반드시 수렴하여야 한다. 그리고 교원노조의 가장 중요한 과제는 이념투쟁이 아니라 단체교섭을 통한 현장교육문제의 해결이라는 의견이 지배적이었다. This study has analysed the teacher's understanding of the 'Law for the Teacher's Union, activities and collective bargaining and showed their claims for the desirable activities from Korean Teachers and Educational Workers' Union. This study proposed studying assignments to achieve this kind of studying purpose as follows. First, how do the teachers think of 'Law for the Teacher's Union' and what's its problem? Second, how do the teachers think of teachers' union system and what's its improvement? The sample of this study was 342 teachers who work at an elementary, middle and high schools in Tae-baek City, Kang-won Province. Of 342 questionnaires distributed, 308 were returned (response rate was 90.1%), but of 308 questionnaires unreliable 18 were exempt from the application of these samples. This questionnaire data were composed of 32 questions. This statistical methods for data processing were frequencies analysis and Chi-sqare tests by SPSS to find a correlation between individual variation and each questions. This study was analysed as p<.05 within a significant level The conclusion that resulted from the data analysis were as follow. First, the admission of teachers' union of school unit should be decided through full discussion and profound debate, but in reality, the establishment of school unit is impossible because of conflict problems among the teachers' position Second, the permission of both a collective action and political activities of Korean Teachers and Educational Workers' Union also has to be profoundly discussed because it can be different from teachers' position, their career, or a member of union whether or not. If it is permissible, its permission should only be approved within its limit without a bad influence on study right and teaching-learning, therefore such results are undesirable. Third, according to the law now in force, agenda of collective bargaining is subjected to restriction in elevation of economical and social position of teacher. In spite of being an educational policy now, however, it is necessary for the teachers to expand that as the agenda of collective bargaining as to employment. The dual collective bargaining system of KTEU(Korean Teachers and Educational Workers' Union) and KFTA(Korean Federation of Teachers' Associations) can have an effect of checks and balances. Fourth, a member of union has to act within the limit of the law and manager should reciprocally endeavor to form democratical administration because a conflict between manager and a member of union in school causes a schism between two parts. Finally, collective agreement between the superintendent of education and teachers' union should be entered into an agreement through procedures of collecting sufficient public opinion. the problem which confronts teachers' union should try to find a solution to the problem without being split in teachers' profession. Moreover teachers' union should be in search of a better solution. It is necessary for pressure group, and to act through playing careful attention to the tends of public opinion and policy-making.