뇌사환자의 갑상선 기능, 전신대사 및 중증도에 관한 연구

이영주,정금희,왕희정,문봉기,한연희,이영석 아주대학교 의과학연구소 1999 아주의학 Vol.4 No.1

Background and Objectives : Brain death may lead to hormonal depletion, metabolic derangement and multiple organ dysfunction. We have carried out present study to examine the effects of brain death on the thyroid function, metabolic indices, and the severity scoring systems. Methods : 13 adults patients admitted for organ donation or brain death evaluation were examined after brain death was confirmed. Thyroid hormones measured were .thyroid stimulating hormone (TSH), triiodothyronine (T3), thyroxine (T4), and free thyroxine (FT4). The metabolic indices measured were arterial ketone body ratio (AKBR), lactic acid (LA), and base defiat (BD). as for reference to the severity scoring systems, APACHE Ⅲ and multiple organ failure score (MOFS) were assessed on the day of brain death confirmation. Arterial blood was drawn for all measurements. Results : As for the thyroid function, there were significant decreases in T3 (40.48±20.96 ng/dL) and T4 (3.47±2.15 ㎍/dL), but no significant change in FT4 (0.75±0.31 ng/dL) and TSH (1.12±1.37 uIU/mL) compared to the normal range. Significant decreases in AKBR (0.39±0.31) and BD (-9.46±5.83 m㏖/L), and significant increase in LA (2.57±2.46 m㏖/L) In metabolic indices, were shown, as for severity scoring systems, APACHE Ⅲ score (101.54±19.41) and MOF score (9.11±2.57) indicated a high mortality. There were significant correlation between thyroid hormones (r=0.565 -0.781) but no correlation among other indices. Also, significant inverse correlations were shown between base deficit and lactic acid (r=-0.660), APACHE Ⅲ score (r=-0.726) and MOF score (r=-0.604). The highest correlation was observed between APACHE Ⅲ score and MOF score (r=0.851). Conclusions : As for the thyroid function, significant decrease in T3 and T4, and almost normal range of FT4 and TSH imply the euthyroid sick syndrome. Abnormal finding of the metabolic parameters indicates an inhibition of the aerobic metabolic rate of the body as a whole. And the severity scoring parameters are compatible with high mortality.

배양상태의 흰쥐 뇌하수체 앞엽에서 Neuropeptide Y 함유세포에 관한 면역조직화학적연구

이화영,김순회,이희래,어환,이왕재,백상호,이병란 대한해부학회 1996 Anatomy & Cell Biology Vol.29 No.3

재식한 치아에서 수산화칼슘을 사용한 근관치료

이상호,이창섭,김왕근,문상희 大韓小兒齒科學會 1999 大韓小兒齒科學會誌 Vol.26 No.1

외상으로 인해 치근 완성 여부가 불분명한 완전탈구된 치아를 재식한 후 18개월 여간 관찰하여 다음과 같은 결과를 얻었다. 1. 재식 초기의 염증성 치근 흡수는 수산화 칼슘을 사용한 근관치료로 억제될 수 있었다. 2. 치근 완성 여부가 불확실한 치아에서 조기 근관치료가 염증성 치근 흡수 및 유착의 방지에 더 큰 임상적 성공을 얻을 수 있었다. 따라서, 재식 당시 치근첨의 개방성 여부가 명확하지 않을 때에는 성인의 치료 지침에 따라 치료하는 것이 보다 효과적이며, 불가피할 경우에는 환자 및 보호자의 철저한 교육에 뒤따른 정확한 내원 약속이 속발증을 최소화 할 수 있을 것으로 사료된다. Tooth avusion implies total displacement of teeth out of its socket. Its frequency range from 0.5 to 16% of traumatic injuries. Replantation procedure is used for the treatment of avulsed tooth. However, its major complications are pulp necrosis, inflammatory root resorption and replacement root resorption. This paper describes 10 years and 2 minths old male patient whose both maxillary central incisors were avulsed due to fall-down with slightly underdeveloped root apices. Teeth were replanted 2 hours after accident. Right central incisor's pulp tissues were extirpated and filled with Vitapex (calcium hydroxide) at 3-4 weeks after replantation, but left central incisor was filled at 8-9 weeks. Right central incisor showed little inflammatory resorption in apical portion, whereas left central incisor showed severe root resorption. During 18months' follow-up period, left central incisor showed slightly ankylosis while right central incisor did not. Based upon the above-mentioned results, the following conclusions can be drawn: 1. Inflammatory resorption could be suppressed by endodontic treatment with calcium hydroxide. 2. When apex formation is doubted in replanted tooth due to avulsion, early endodontic treatment with calcium hydroxide seems to act positively for better prognosis.

미생물 실험실 안전에 관한 조사 연구 : Ⅲ. 실험실 생물재해 관리 Ⅲ. Control of Biohazard in the Laboratory

이호왕,김주성,정윤섭,정희영,장우현 대한감염학회 1990 감염 Vol.22 No.1

The response to an emergency resulting from an accident involving micro-organisms, whether in laboratory or during transit, needs to be graded according to the degree of hazard to human created by the circumstances of the accident and the properties of the organisms concerned. Kim and Lee(1988) reported 102 laboratory acquired infections among 2,417 laboratory workers during 1981-1985 in Korea. It is estimated 8.28 infections annually per 1,000 laboratory workers. A catagorization of micro-organisms by risk group is proposed for the purpose of accident management, and classification of etiological agents on the basis of hazard in Korea has published by Kim and Lee et al (1988) as a general reference for some laboratory activities utilizing infectious agents. This publication will provide specific descriptions of combinations of microbiological practices, safety equipments, and laboratory facilities and recommendations for use in four categories or biosafety levels of laboratory operations with selected infectious agents of man. Recommendations for biosafety levels for specific agents are made on the basis of the potential hazard of the agent and of the laboratory function or activity.

두개인두종의 소아와 성인에서의 임상적 특성 및 수술적 치료결과

이선호,민경수,왕규창,정희원,김현집,조병규,최길수,한대희 대한신경외과학회 1991 Journal of Korean neurosurgical society Vol.20 No.4

The records of 59 patients with craniopharyngioma treated at the Department of Neurosurgery. SNUH, from Jan. 1981 to May 1990 were reviewed in order to compare the characteristics of the tumor in children and adults in view of clinical features, radiological findings, surgical results and follow-up outcome. This study was also done to evaluate the outcome and recurrence rate according to the extent of surgical removal between the two groups. Of the 59 patients, 22 patients were under the age of 15 and 37 patients were adults. In the child group the most frequent presenting symptoms were IICP symptoms(63.6%) followed by visual disturbance(27.3%) whereas visual disturbance(51.4%)were more often than IICP symptoms(24.3%) in the adult group. In the radiologic findings calcification(95.5%) and cystic change(95.5%) were more common in the children than the adults. In the adults calcification showed in 59.5% of patients and cystic change showed in 86.5% of patients. Hydrocephalus was noticed in 63.6% of the children whereas 16.2% of the adults showed hydrocephalus on the CT scan. Twenty-five operations were undertaken for 22 children and 39 surgical procedures were performed for 37 adults. Most of the surgical procedures were carried out by the pterional or subfrontal approach or a combined approach. Eighteen child patients and 12 adult patients underwent total removal and 3 child patients and 14 adult patients underwent subtotal removal. Surgical results were good in 33 adult patients and in 21 child patients. One patient died postoperatively after partial removal due to pulmonary embolism. The mean follow up period was 27.0 months in children and 22.6 months in adults. Clinical recurrence study with the subtotal and partial removal group revealed that recurrence happened more often and in a shorter period of time in children. Presumed factors influencing the total removal of tumor such as age, symptom duration, cysic portion, calcification, size and location of mass were analyzed. The total removal of the tumor is the best method of treatment however, the recurrence rate in cases of subtotal removal, the possibility of total removal and the morbidity accompanying total removal, were also considered in planning the surgical treatiment.

行政學 理論體系 定立을 위한 方法論的 認識

李汪宰,安熙南 상명대학교 논문집 1985 상명대학교논문집 Vol.15 No.-

It has been often recognized for that the discipline of public administration is plagued by a weak or absent theoretical framework and core. This has led some social scientists, along with Robert Parker, to conclusion in which "there is really no such subject as 'public administration'. No science or art can be identified by this title, least of any single skill or coherent intellectual discipline." Others, including Frederick C. Mosher, have considered it a "resource", that public administration "is more an area of interest than a discipline," since this enables the field to draw upon a variety of disciplines. Still, another group of scholars, such as Herbert Kaufman and James Q. Wilson, have argued that public administration faces a serious and seemingly irresponsible problem in continually seeking to maximize the attainment of mutually incompatible values. Public administration theory contains at least three distinctive approaches. These can be labeled "managerial", "political", and "legal", Each approach has relatively separate origins, emphasizes different values, promotes different organizational structures, and views individuals in different terms. These three approaches reflect the constitutional separation of powers, which has tended to collapse into the administrative branch as a consequence of the rise of the contemporary administrative state. The development of a more coherent body of public administrative theory must recognize the utility of each of these approaches as they are applied to various aspects of administration. The experiences of practitioners, whose effort is totry to integrate these approaches on the job, can be an invaluable guide to such theory-building. This paper identifies the problems and issues concerning to the theory building of public administration in Introductory. It deals with the different methodologies, mainly borrowed from neighborhood disciplines, for the public administration theory in Chapter Ⅱ(The Methodology of Public Administration) and tries to integrate them into a new dimension of managerial, political and legal approaches in Chapter Ⅲ(A Practical Cognition for the Systematization of Public Administration Theory). Finally, it stresses the importance of public administration theory to solve the actual problems, to realize the social values and to control the unpredictable future.

한국 프로농구 선수들의 성격 특성에 관한 조사 연구

이종희,송왕국 경희대학교 체육과학연구소 2001 體育學論文集 Vol.29 No.-

The aim of the study is examining the influence of elementary schoolchildren's Taekwondo training on their sense of self-respects. The subjects of the study are the boy students of the fourth, fifth, and sixth school year of elementary schools in Seoul at the present time, and the method of sampling from the population is the multi-stage cluster sampling. The way of data gathering is that let the subjects write out questionnaires using the self-evaluation recording, and the 326 person's data on material examination process is analyzed by IBM PC SAS Package. The methods of analysis include the confidence level verification by sub-areas, examination of questionnaires, re-examination of confidence level, computing the average and the standard deviation by each of 4 self-respects areas unitary variable quantities analysis and the Tukey's post data verification. The results of the study over the influence of elementary schoolchildren's Taekwondo training on their sense of self-respects from the methodologies and process above draw conclusions like follows: 1. The fifth school year students gained the highest mark following the fourth, and the sixth school year in the whole, social, home, and school life senses of self-respect by school year, but the differences among them are meaningless statistically. 2. The training students marked higher than the training experienced students in the whole, social, home, and school life senses of self-respect by whether they have trained or not, but the differences among them are meaningless statistically. 3. According to the grades, the meaningful differences between the Poom(senior grade) holders and the Keup(junior grade) holders(p=0.0009) was showed in the whole senses of self-respect, and the social senses of self-respect was differed much between the Poom holders and 8-4 Keup holders(p=0.0058), the home life senses of self-respect between the 3 Poom holders and the Keup holders, 1-2 Poom holders and 8-4 Keup holders showed meaningful differences(p=0.0010), but the differences in the school life senses of self-respect are meaningless statistically. 4. According to personal career, the differences have something significants in the whole senses of self-respect among the students who have trained over 3, 2-3 years and less than 1 year(p=0.0062), in the social senses of self-respect among the students who have trained over 3, 2-3, 1-2 years and less than 1 year(p=0.0103), and in home life senses of self-respect between the students who have trained over 3 years and 1-2 years or less than 1 year, between 2-3 years and less than 1 year(p=0.0004), but the differences in the school life senses of self-respect are meaningless statistically.

液體誘電體(실리콘油) 誘電正接의 溫度 및 周波數依存性

김왕곤,이돈희 서울산업대학교 산업대학원 1993 大學院論文集 Vol.2 No.-

Silicon oil exhibits the properies of both organic substances, thus it has many superior properties such as higher thermal resistance and lower thermal oxidation level when comlared to other dielectric liquid. However, its inherent feature to impurities and humidity and other gases makes it difficult to study its physical properties. In order to investigate the dielectric characteristics, dielectric liquid of viscosity 1〔cSt〕 is chosen as the specimen and experiment is performed in the temperature range of 20∼65〔℃〕and frequency range of 30∼?? As a result, the observed linear decrease in tanδvalue at the frequency range below 3〔kHz〕is due to the influence of frequency, where as the increase in tanδvalue at higher frequency range is contributed by electrode's resistance. At a fixed frequency of 30〔kHz〕, increasing temperature results in higher peak value and wide width of the absorption curve. This is due to the increase in dipole and viscosity. As temperature increases, dipole moment is decreased from 0.98 to 0.64〔debye〕. The activation energy which causes the relaxation and loss of dielectric is obtained about 15〔kcal/mole〕.

복합 운동프로그램이 초등학생의 신체구성, 혈중지질 및 체력에 미치는 영향

전종귀,이왕록,박희근,정준현,이영란,신동원,이경숙 충남대학교 체육과학연구소 2006 體育科學硏究誌 Vol.23 No.1

The purpose of the present study was to examine the effects of combined training on the changes of body composition, blood lipid profile and fitness in elementary school students. Thirty subjects participated in the present study. The subjects were divided into two groups either exercise group for 10weeks(15n) or control group for 10weeks(l5n) The results were described as follows; 1) There were significant differences in the body weight and lean body mass after the exercise program between two groups. 2) There were no significant differences in the blood TC, HDL-C, LDL-C, TG concentration after the exercise program between two groups. 3) There were significant differences in the sit-up and flexibility after the exercise group between two groups. In conclusion, it might be thought that the combined training improved the levels of body composition and health-related fitness in elementary subjects.

원발성 중추신경계 임파종 : 치료 및 생존율 Treatment and Survival Rate

남도현,이상형,김동규,정희원,지제근,왕규창,김현집,최길수,한대희 대한신경외과학회 1993 Journal of Korean neurosurgical society Vol.22 No.3

The authors report on 17 patients having primary central nervous system(CNS) lymphomas between January, 1981 and August, 1992. All patients were treated at Seoul National University Hospital. Only three cases underwent surgery only and fourteen cases underwent surgery and radiation therapy with or without chemotherapy. There were no immunosuppressive patients. Sixteen patients were analyzed for survival studies, because one case was lost during follow-up. The median survival time(MST) was 26 months and one- and two-year survival rates for the 16 patients were 87.5% and 65.6% respectively. The rate of survival was analyzed according to possible prognostic factors ; age and sex, multiplicity and location of tumors, preoperative Karnofsky performance score(KPS), pathological subclassification, type of surgery, preoperative steroid therapy, postoperative adjuvant therapy, extent of radiation, chemotherapy and the degree of response to treatment at three months follow-up. Postoperative adjuvant therapy and the degree of response to the treatment correlated with survival. Fourteen patients who underwent postoperative adjuvant therapy had a median survival time of 63 months. The one- and two-year survival rates were 100% and 75% respectively compared to the MST of 1.5 months with survival rates of 0% and 0% retrospectively for the two patients who did not. A higher long term survival rate was observed in the group with better immediate responses. In nine of 16 patients with complete responses, the MST, one-, and two-year survival rates were 63 months, 100%, and 83% respectively. The authors suggest that preoperative application of steroids may be considered in case of clinically suspected primary CNS lymphomas. It is concluded that after obtaining the tissue diagnosis of primary CNS lymphomas, radiotherapy with or without chemotherapy should be performed until the complete response.