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어환,심보성 대한신경외과학회 1981 Journal of Korean neurosurgical society Vol.10 No.2
The computed tomographic scan has revolutionized the management of head trauma and has been established as an accurate diagnostic modality. The computed tomography was performed in 308 head injured patients and those findings were retrospectively analyzed. A wide spectrum of traumatic abnormalities was demonstrated by computed tomography. Seventy-six percent of patients had abnormal scans. The yield of abnormal scans varied with Glasgow coma scale at the time of scans: GCS 15-13, GCS 12-9, 91%: GCS 8-6, 94: GCS 5-3, 100%. Not significant correlation was found between the score of GCS and the extent of the midline shifting on the CT scan (P>0.05) Acute subdural hematoma and intracerebral hematoma were commonly associated with the other lesions, and over 2/3 of intraecrebral hematoma combined acute subdural hematoma.
9L 쥐 뇌종양에 있어서 체내 BrdU 표식지표와 체외 BrdU 표식지표의 비교
어환,長島正,松谷雅生,高倉公朋 대한신경외과학회 1992 Journal of Korean neurosurgical society Vol.21 No.12
The study of in vivo bromodeoxyuridine labeling index(BrdU LI) has become an established method alongside conventional histopathologic study for more complete and reliable evaluation of the biological behavior of tumors. However, in vivo BrdU LI study was limited because of requiring patient selection and patient consent In order to compare in vitro BrdU LI with in vivo one, the authors used 15 rats whose brains were stereotactically implanted with 9L glioma cell suspension, and incorporated BrdU into tumors in vivo or in vitro. In vivo BrdU LI was 18.3± 2.1 % ; in vitro LI of tumors incorporated BrdU within 30 minutes after tumor removal was 11.8± 2.6% ; in vitro LI of tumors incorporated 2 hours after removal was 9.7± 0.8% ; in vitro LI of tumors incorporated 4 hours after removal was 6.5± 3.0%. In vitro LIs were significantly lower than in vivo LI(p<0.05), and in vitro LI decreased gradually as the time of BrdU labeling passed But there were not statistically significant among in vitro LIs. In conclusion, it is essential to incorporate BrdU into tumor cells as soon as possible after tumor removal for in vitro BrdU LI. and in vitro LI is considered to take the place of in vivo LI for the evaluation of proliferating activity of tumor cells.
흉추강내에 발생한 Angiofallicular Lymph Node Hyperplasia 1예 보고
어환,홍승관,한대희,지제근,김용일 대한신경외과학회 1980 Journal of Korean neurosurgical society Vol.9 No.1
Angiofollicular lymph node hyperplasia is a relatively rare benign lesion. In 1954 Castleman described the first case of this process occurring in the anterior mediastinum. This lesion was subsequently described in a number of case reports under various names including Castleman's disease, lymph nodal hamartoma, follicular lympho-reticuloma, angiofollicular lymph-node hyperplasia, angiomatous lymphoid hamartoma, and benign giant lymphoma. Although the mediastinum is the most common location, they also occur in other areas of the body, usually where lymph nodes are normally found. However, intraspinal location has been seldom described in literatures. Recently, authors experienced a case of angiofollicular lymph node hyperplasia in the thoracic spinal canal, which was operated upon for paraparesis below T10, in a 17 year old male. The tumor was located between the levels of T8 to T10, and was encircling the subjacent spinal cord. This lesion was successfully removed. The patient is in good condition postoperatively. A brief review of pertinent literatures was made.
CT로 진단된 두부 손상 환자의 뇌간 출혈 2예 보고 : Case Report
어환,이현구,조병규,심보성 대한신경외과학회 1981 Journal of Korean neurosurgical society Vol.10 No.1
Computerizd tomography has been proven to be of particular value in patients with head trauma. Neverthless, primary traumatic brainstem lesions are not always revealing even by the advent of brain CT. In two cases of head trauma, we identified midbrain hemorrhage by CT scan. One of them was hemorrhage in the quadrigeminal plate, the quadrigeminal cistern, and the vermis; the other small round isolated hemorrhage in the quadrigeminal plate. They were well correlated with the clinical findings. Those two patients got well with conservative treatment.
서승근,어환,주인욱,송준호,박세혁,정봉섭,권병덕,이규호 대한신경외과학회 1988 Journal of Korean neurosurgical society Vol.17 No.5
Selective arterial embolization can reduce the size and pressure within the nidus of the arteriovenous malformations (AVMS) and diminish the number of feeding pedicles, making subsequent surgical excision technically easier and safer, especially in those AVM patients whose lesions are judged to be inoperable or resectable with major risk. Authors have successfully and repeatedly performed selective arterial embolizations with polyvinly alcoholfoam(PVA foam) and isobuty1-2-cyanoacrylate (IBCA) to a large AVM at the left basal ganglia, thalamus and lateral ventricles, and a large cortical AVM near right motor strip.