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Norfloxacin 및 ciprofloxacin의 호기성 그람음성 간균 및 Staphylococcus aureus에 대한 항균력
정윤섭,김현옥,이삼열 대한화학요법학회 1988 대한화학요법학회지 Vol.6 No.2
Activities of norfloxacin and ciprofloxacin against aerobic gram-negative bacilli and Staphylococcus aureus isolated in 1988 were tested by the agar dilution method. MICs of ciprofloxacin were much lower than those of norfloxacin. All of the isolates of Enterobacter iaceae with the exception of some Serratia marcescens were inhibited by very low concentrations of the quinolones. Some of the Pseudomonas aeruginosa and P. maltophilia isolates were inhibited by higher concentration. Some of the Acinetobacter anitratus isolates were inhibited by high concentration of norfloxacin, but MIC of ciprofloxacin was low. Norflorxacin-resitant P. aeruginosa isolates were also resistant to ciprofloxacin, but gentamicin-resistantnt gramnegative bacilli and methicillin-resitant S. aureus did not show cross resistance to the quinolones.
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정윤섭,이삼열 대한화학요법학회 1984 대한화학요법학회지 Vol.2 No.1
Antimicrobial susceptibilities of anaerobic bacteria to moxalactam and a few other cephalosporins were compared. The strains tested were some of the isolates obtained from ciinical materials in 1982-1984. Agar dilotion method TTas used and the ioLiomng results were obtained. The ainimum inhibitory concentration (MIC) of moxzlactzm against strains of Bacfei oides -fragzEis, B. t7zeiazota~?nzrron and Bacfs?mdec sp. vere 1-52 ,ug/mi whiie the MIC of cephahthin, cefcperazone and cefotaxime mere i6->i28 ,ug/mi. The MIC of moxalactam agaii-st anaero3ic grzm-positive cocci were either slightly higher, sligltly iower or similar compared t o the MIC of cther cephalosporins. Moch higher proportion of the test organisms mere interpreted scscep~ible to noxaIactam than to other cephalosporins. Considering the facts t h a t anaerobic infections are usually mixed Rith aerobic and facultatire organisms and that moxalactam is active against both aerobes and anaerobes, it is concluded that selection of moxalactam is reasonable in such infectiom.
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鄭允燮 부산 외국어 대학교 1990 外大論叢 Vol.8 No.1
보들레에르의 시를 구성하는 기본적인 요소들 중에 특히 눈에 띄는 것들 중의 하나는 비교적 풍부한 그 대비, 대조의 기법이다. 이미 그의 초기 시편인 <Albatros>나 <Une Charogne> 등을 보더라도, 「대담한 역설의 새로운 형태로 표현되는, 말하자면 아름다움과 상스러움, 선과 악, 이상과 현실, 삶과 죽음」등의 그의 시의 일종의 라이트모티프와 같은 것으로 나타나 있음을 알게 된다. 그러나 역설적 대비는 때로는 빛과 그늘, 명과 암, 흑과 백의 대비 형태로 나타나기도 한다. 한편, <어둠>의 형상은 그의 시집 「악의 꽃」의 서시인 「독자에게」Au Lecteur에서부터 이미 「악취풍기는」 모습으로서 충격적으로 등장한다. 그것은 곧 이어 「악마」, 「죄악」, 「지옥」, 「암흑」, 「죽음」, 등 <악과 흑의 이마쥬>와 상호보완적으로 연결된다. 그런데 마르셀 뤼프에 의하면, 특히 18세기의 작품들, 즉 디드로의 「철학적 단상」Pensees philosophiques, 라끌로의 『위험한 관계』 Les liaisons dargereuses 등등에 열중했던 결과로 배워온 강력한 미학적 수법이 즉 「놀람」 surprise과 「충격」 choc의 기법이며, 그 중에서도 가장 효과적인 것이 「난포」violence, 「공포」 terreur, 「참혹」 horreur-말하자면 「악의 도발적인 여러 형태들」 les formes agressives du mal-이라고 한다. 이것들은 자연히 「어두운 빛깔」 couleurs sombres 을 띠게 마련이다.
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Coagglutination에 의한 $\beta$-용혈성 연쇄구균의 혈청군 동정
정윤섭,윤양숙,김윤정,이삼열,김성광,이병수,김주덕,Chong, Yun-Sop,Yoon, Yang-Sook,Kim, Yoon-Chung,Lee, Sam-Uel Y.,Kim, Sung-Kwang,Lee, Byung-Soo,Kim, Joo-Deuk 대한미생물학회 1979 大韓微生物學會誌 Vol.14 No.1
Identification of group A $\beta$-phemolytic streptococci is very important to provide an appropriate preventive measure of possible rheumatic fever and acute glomerulonephritis. For such purpose bacitracin susceptibility of streptococci because of its simplity has been most widely used despite of its occasional faulty results. Recently, a coagglutination technique was advocated using streptococcal group specific antibodies adsorbed to protein A-containing staphylococci. This study was conducted to evaluate the coagglutination technique using reagents prepared by ourselves. The specificity, reproducibility and stability were ascertained and the following results were obtained. 1. The identification by coagglutination technique using our own reagent gave the same results compared with the Lancefield precipitation technique. The result also agreed with the Phadebact grouping. 2. There were no variation in group A and B identification due to lot difference. However, there were a few discrepant results in group C and G identification which was conducted in different days with different lots of our reagent. 3. The stability of our reagents was less satisfactory compared to the commercial product. An effort to improve the stability was considered necessary. 4. For coagglutination, it was found convenient to use supernatant of Todd-Hewitt broth incubated for 24 hours. Both parafin-ringed slide glass and RPR card gave comparable results and the former could be used when the latter is not available.
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정윤섭 대한흉부심장혈관외과학회 1990 Journal of Chest Surgery (J Chest Surg) Vol.23 No.1
Between Jan. 1962 and Dec. 1988 380 cases of palliative operations were done in 357 patients for congenital heart disease. These includes 55 cases of classic Blalock-Taussig shunt, 212 cases of modified Blalock-Taussig shunt, 17 cases of Glenn shunt, 26 cases of Waterston shunt, 3 cases of Brock procedure, 33 cases of pulmonary artery banding, 6 cases of transpulmonary valvotomy, 4 cases of unifocalization, and 10 cases of open atrial septectomy. We divided the operative procedures into the conventional and the unconventional. Under the unconventional procedures, the cases since April, 1986 were only included. The number of patients who died within the early 30 days after operation is the following: 40 in systemic-pulmonary shunts, 2 in Brock procedure, 12 in PAB, 15 in unconventional procedures. The age of the patients who need palliative operation is lowering more and more and their characteristics of the disease is being transferred to the more complexities. So the role of palliative surgery in the congenital heart disease is changing.
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