Gerrit T. Rietveld의 건축조형특성에 관한 연구 : 1920년대 초기 가구와 건축작품을 중심으로 Focused on Early Furniture and Architecture in 1920's

정혜은,이용재,양상현 순천향대학교 부설 산업기술연구소 2003 순천향 산업기술연구소논문집 Vol.9 No.1

The purpose of this study is the plastic characteristics in architecture of Gerrit T. Rietveld focused on early works. Gerrit T. Rietveld was furniture designer and architecture that played an active part in De Stijl. And he was famous for De Stijl's member with Piet Mondrian and Theo van Doesburg. Specially, early works of Gerrit T. Rietveld influenced a plastic methods by De Stijl. The results of this study are as follows. Gerrit T. Rietvel tried developing composition of the three dimensions space to abstract painting. As a result of his try, probably the first actual building to embody the full range of De stijl formal, spatial and iconographic intentions was therefore the Schröder House. Gerrit T. Rietveld expressed 'dematerility' to architecture as well as furniture. So he could complete works of art including function.

다중 중합효소 연쇄반응을 이용한 반코마이신 내성 장구균의 신속 검출

박성언,박수진,엄용빈,김종배,송혜원,박상욱,김양수,김근희 THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCIEN 1999 Journal of biomedical laboratory sciences Vol.5 No.1

일반적으로 임상검사실에서 vancomycin resistant enterococci(VRE)를 검출하는 일은 어렵고, 시간이 많이 들며, 검체처리 비용도 많이 든다. 따라서 본 실험은 임상검체에서 분리된 세균으로부터 VRE를 신속하게 확인하고, 진단하기 위한 방법으로서 다중 중합효소 연쇄반응을 확립하였다. 본 실험에 사용된 primer는 장구균에 특이한 유전자인 vanA, vanB, vanC-1, vanC-2/3각각의 염기서열을 기초로 primer를 제작하고, 다중 중합효소 연쇄반응을 실시하여 임상검체로부터 분리된 VRE 유전자의 type 및 분포율을 조사하고자 하였다. 국내에서 분리된 75주의 장구균을 대상으로 다중 중합효소 연쇄반응을 실시한 결과 36주의 분리균주에서 vancomycin에 대해 높은 저항성을 보이는 vanA 유전자를 가진 것으로 나타났다. 그리고 18주에서는 vancomycin에 낮은 저항성을 내성을 보이는 vanC-1또는 vanC-2/3유전자를 보유한 것으로 나타났다. 따라서 본 실험에서 확립한 다중 중합효소 연쇄반응 기법은 신속한 VRE 진단 방법으로 이용할 수 있을 것이다. It is generally difficult, time-consuming, and expensive for the clinical laboratory to detect vancomycin resistant enterococci (VRE). The aim of this study was to develop and evaluate the multiplex polymerase chain reaction (PCR) assay system as a diagnostic tool for the rapid detection of VRE from clinical samples and/or for the identification of VRE from the bacterial strains isolated from clinical specimens. Specific primers, designed from the nucleotide sequences respectively encoding the vanA, vanB, vanC-1, vanC-2/3 genes in enterococci, were coupled in a multiplex PCR assay system. With this multiplex PCR assay system, we investigated the incidence rates and types of VRE isolated from clinical samples. A total of 75 strains of enterococci were isolated in 3 general hospitals in Korea. Of these isolates, 36 strains showed a pattern of highlevel vancomycin resistance which associated with vanA gene, whereas 18 strains showed lowlevel vancomycin resistance associated with vanC-1 or vanC-2/3 gene. Thus, multiplex PCR assay method established in this study could be applied for the rapid detection of VRE.

서울지역 가정주부의 초기상실 경험과 생활 사건이 우울에 미치는 영향

사승언,양병환,백기청 大韓神經精神醫學會 1996 신경정신의학 Vol.35 No.2

For the purpose of unraveling whether early loss influences the later depression, 500 housewives in the Seoul area were sampled by the multi-stage probabilistic stratified sampling. The Beck Depression Inventory (BDI) and the Life Event Stress Rating Scale of Housewives (LERS) constructed by Yoo et al. (1994) were administered to all the subjects. Early loss was defined as the loss before 15 years of the subjects age. The early loss, as a whole or as in sperate age groups, proved to have no influence on the BDI score. In the younger groups under the 50 years of age, the early loss according to each area of recent life event stress did not affect BDI score. But, only in the elderly group over the age 50, the experience of recent life event stress was proved to have influence on the BDI score in the early loss group. The early loss group, compared to the loss-free group, was lower in the BDI score when they had no experience of stress factors "the economy and job" and "the change of life circumstance", but equivalent when they had experience of the above stresses. The early loss group was lower in the BDI score when they had no experience of stress factor "separation", but higher in the BDI score when they had experience of stress of recent separation. The above findings suggest that the early loss group, with no experience of recent stress, is less depressed in the elderly life than the loss-free group and the recent life event such as "the separation" possibly provokes depression in the early loss group.

임플랜트 고정체의 형태와 연결방식에 따른 임플랜트 및 지지조직의 응력분포

한상운,양홍서 전남대학교 치의학연구소 2003 구강과학 Vol.15 No.2

In this study, four finite element models were constructed in the mandible having a single implant fixture connected to the first premolar-shaped superstructure, in order to evaluate how the shape of the fixture and the implant-abutment connection would influence the stress level of the supporting tissues, fixtures, and prosthethic components. In each model, the superstructures were constructed using UCLA type abutment, ADA type Ⅲ gold alloy was used to fabricate a crown andthen connected to the fixture with an abutment screw. The models BRA, END, FRI, ITI were constructed from the mandible implanted with Branemark, Endopore, Frialit-2, I.T.I systems respectively. In each model, 150 N of vertical load was placed on the central pit of an occlusal plane and 150 N of 40˚ oblique load was placed on the buccal cusp. The displacement and stress distribution in the supporting tissues and the other components were analysed using a 2-dimensional finite element analysis. The maximum stress in each reference area was compared. The results obtained were as follows : 1. Under 40˚ oblique loading, the maximum stress was larger in the implant. superstructure and supporting tissue, compared to the stress pattern under vertical loading. 2. In the implant, prosthesis and supporting tissue, the maximum stress was smaller with the internal connection type (FRI) and the morse taper type (ITI) when compared to that of the external connection type (BRA & END), 3. In the superstructure and jmplant/abutment interface. the maximum stress was smaller with the internal connection type (FRI) and the morse taper type (ITI) when compared to that of the external connection type (BRA & END). 4. In the implant fixture, the maximum stress was smaller with the internal connection type (FRI) and the morse taper type (ITI) when compared to that of the external connection type (BRA & END). 5. The stress was more evenly distributed in the bone/implant interface through the FRI of trapezoidal step design. Especially Under 40˚ oblique loading, The maximum stress was smallest in the bone/implant interface. 6. In the implant and superstructure and supporting tissue, the maximum stress occured at the crown loading point through the ITI. In short, the stress distribution of the supporting tissue was affected by shape of a fixture and implant-abutment connection. The magnitude of maximum stress was reduced with the internal connection type (FRI) and the morse taper type (ITI) in the implant, prosthesis and supporting tissue. Trapezoidal step design of FRI showed evenly distributed the stress at the bone/implant interface.

당뇨병환자에서 게이트심장혈액풀신티그라피를 이용한 심기능 평가

윤상임,송치운,이진홍,안미애,성기양,송민호,이강욱,신영태,김영건,노흥규 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

Major cardiovascular complications of diabetes are coronary atherosclerosis, diabetic dilated cardiomyopathy, autonomic neuropathy and those are major causes of morbidity and mortality in diabetic patients. Gated blood pool heart scan is noninvasive and useful method for evaluation of functional status of heart in diabetics. We evaluated 52 patients with diabetes and divided 3 groups. Group 1 were 11 patients without proteinuria or with proteinuria less than 550mng during 24 hours. Group 2 were 9 patients with proteinuria more than 550mg during 24 hours and group 3 were 32 patients with endstage renal diasese due to diabetes. We performed 99mTc-HSA cardiac gated blood pool scan and used left ventricular ejection fraction(LVEF), peak ejection rate(PEF) to indices of LV systolic function and peak filling rate(PER) to index of LV diastolic function. The results were follows : 1) LVEF, PER were significantly lower in diabetics with ESRD than diabetics without ESRD, but there were no significant difference between normal controls and diabetics without ESRD 2) PFR was significantly lower in diabetics than normal controls, but there were no significant differences in diabetics with or without nephropathy. 3) There were negative correlation between PER, PFR and duration of diabetes. On the basis of results, PFR is a LV functional index of GBPS which can disclose early change of LV dysfunction in patients with diabetes.

혈액투석중인 만성신부전 환자에서 골대사 지표로써의 Osteocalcin치

송치운,이진홍,안미애,윤환중,윤상임,성기양,이강현,송민호,이강욱,신영태,김영건,노흥규 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

Background : Serum osteocalcin is synthesized by osteoblast and has been shown to be sensitive indicator of bone turnover inpatients with various metabolic bone disease. In renal osteodystrophy, serum osteocalcin is elevated due to decreased renal clearance and elevated level of PTH. This study was done to evaluate the usefulness of serum osteocalcin as a marker of bone metabolism and the correlation with other biochemical markers of bone metabolism. Methods : We measured serum osteocalcin, calcium, phosphorus, ALP(alkaline phosphatase) and PTH(parathyroid hormone) in 37 patients with end stage renal disease on hemodialysis. Osteocalcin was determined by radioimmunoassay and PTH was determined by radioimmunometric assay. Results : 1) The mean level of serum osteocalcin in ESRD patients was 233.8± 218.2ng/ml which was significantly higher than that of controls(p<0.0001). 2) The mean level of serum PTH in ESRD patients was 40.5± 43.8pg/ml was significantly higher than that of controls(p<0.005). 3) There was a significant positive correlation between the level of serum PTH, ALP and the level of serum osteocalcin in ESRD patients. 4) By using multiple regression, PTH is most reliable factor that affect to elevated level of serum osteocalcin ( beta coefficient = 0.687, Sig T<0.05). Conclusion : Serum osteocalcin as a marker of bone metabolism in ESRD patients is more useful than other biochemical marker such as serum calcium, phosphorus, ALP and PTH is a most reliable factor that affect to elevated level of serum osteocalin.

HOT WALL EPITAXY방법에 의한 ZnTe/GaAs(100) 박막의 성장과 광학적 특성

남성운,정양준 木浦大學校基礎科學硏究所 1997 基礎科學硏究誌 Vol.15 No.-

ZnTe epilayer of high quality was grown on GaAs substrate by hot wall epitaxy(HWE) methods. The atomic ratio of Zn : Te in the epilayers was found to be almost 1:1 by Rutherford Backscattering Spectrometry(RBS). The best value of the full width at half maximum(FWHM) of the double crystal rocking curve(DCRC) of ZnTe epilayer was obtained 93 arcsec. The PL spectrum with the strong free exciton peaks and no oxygen-bound exciton peaks showed the high quality of the films. From the splitting of the heavy hole and light hole band, the tenslie strain was identified. With the excitation source of 514.5 nm Ar-ion laser, three resonant Raman lines were observed.

적외선 열화상 카메라를 이용한 머시닝 센터 주축 열변위에 관한 열해석

김재열,윤성운,임노빈,유신,마상동,양동조,송인석 한국공작기계학회 2001 한국공작기계학회 춘계학술대회논문집 Vol.2001 No.-

Diagnosis or measurements using Infrared thermo-image hasn't been available. A quick diagnosis and thermal analysis can be possible when that kind of system is introduced to the investigation of each part. In this study, Infrared Camera, Thermo-vision 900 was used in order to investigate. Infrared Camera usually detects only Infrared wave from the light in order to illustrate the temperature distribution. Infrared diagnosis system can be applied to various field. Also, it is more effective to analyze temperature distribution on the machining center main-axis process.

급성 조증에서 기분안정제와 리스페리돈의 병합 투여 효과 : 다기관 개방연구

김광수,배치운,윤진상,김영훈,이양현,지익성,이철,송혜경,최성구,박원명 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.2

Ohjective : The primary purpose of this study was a replication of the effectiveness and tolerability of rispehdone in the treatment of patients with acute mania in very larger cohon in naturalistic treatment setting to extend the data on the effect and tolerability of risperidone in the treatment of patients with acute mania to Asian population. Methods : A total of 909 patients with DSM-TV criteria of bipolar disorder current manic and hypomanic episode, entered this large, open, multicentre study. The Young Mania Rating Scale (YMRS), Clinical Global Impression (CGI) and Simpson-Angus Rating Scale (SARS) were measured at baseline and weeks 1, 3 and 6, for the assessment of effectiveness and extra-pyramidal symptom (EPS). Results : This study showed statistically significant reduction of scores on the YMRS and CGI-s (mean change=-23.5±11.8, p<0.0001 ; mean change=-2.7±1.5, p<0.0001, respectively) from the baseline to the endpoint (week 6). Number of patients with 50% reduction or more in the YMRS and CGI-s scores was 693 (77.8%) and 630 (70.7%) at endpoint, respec-tively. There were no statistically significant increments of scores on SARS. Risperidone was generally well tolerated. Conclusion : The present larger open study demonstrates that hsperidone add-on therapy is effective and tolerable in treat-ment of bipolar disorder, replicating results in various controlled and uncontrolled studies from Western countries.

위선암에서 p53 및 bcl-2 단백질발현에 대한 면역조직화학적 분석

양재표(Ja Pyo Yang),차성재(Sung Jae Cha),박성준(Sung Joon Park),임현묵(Hyun Muc Lim),박성일(Sung Il Park),박언섭(Un Seop Park) 대한외과학회 1998 Annals of Surgical Treatment and Research Vol.54 No.3