대동맥 협착증과 동반된 출혈성 위장관 동정맥 기형에서 Estrogen-Progesterone 치료 1예

김도연,김화정,김효정,남준식,박수영,박영미,신정은,주미순,황민규,정혜경,손혜영,이선영,이한주 大韓消化器內視鏡學會 1999 Clinical Endoscopy Vol.19 No.부록2

오리부산물과 한약재를 이용한 추출액의 영양성분 및 중금속 노출에 대한 피해 완화 효과 : (Ⅱ) 중금속 노출에 대한 오리추출액의 피해 완화 효과 (Ⅱ) Damage Mitigation Effects on Heavy-metals Exposure of Peking-Duck By-Product Extracts

한종현,이우진,조성균,이미정,정미란,전정우,김운영,박성혜 동아시아식생활학회 2003 동아시아식생활학회지 Vol.13 No.4

This study was performed to investigate the effects of peking-duck extracts added with medicinal herbs(DJ) on the intoxication of heavy metals (Hg, Pb, Cd, As) in rats. Sprague-Dawley rats weighing 150±15g, were randomly assigned to 5 groups: basal diet only in normal control group(NCG); basal diet and heavy metals without DJ injection in heavy metal control group(HMC); basal diet, heavy metals and DJ(3㎎/㎖) injection in heavy metal low duck juice group(HMLD), basal diet, heavy metals and DJ(30㎎/㎖) injection in heavy metal middle duck juice group(HMMlD); basal diet, heavy metal and DJ(300㎎/㎖) injection in heavy metal high duck juice group(HMHD). Hg and As was injected by 50ppm and Cd and Pb by 25ppm for 17days. Also DJ oral feeding was conducted for 28days. The result of this study were as follows: Food intake and body weight gain in heavy metal administered groups were lower than those of NCG. Liver, kidney and testis weights were not significantly different among 5 groups. GOT, GPT and BUN activities were significantly reduced in DJ treated groups as compared to HMC. DJ showed the suppressing effect on the accumulation of Hg, Pb and Cd in serum, liver and kidney. Fecal Hg and Cd excretions increased with DJ feeding. The results suggested that DJ may have some protective effects on Hg, Cd and Pb intoxication by reducing the accumulation m tissues and increasing excretion. This study also showed the effective way of using duck-extract and its application to the oriental medicine.

일부 인문계 고등학교 남학생들의 건강행위에 관한 연구

김춘미,최정명,현혜진 韓國學校保健學會 2000 韓國學校保健學會誌 Vol.13 No.1

The Purpose of this study is to analyze the health behavigr of high school studerlts and to find factors influencing it. A questionnaire survey was used for collecting data from 201 male students between May 1 and June 30, 1999. The data were analyzed by the multiple regression techlique in an SPSS package. The major results are as follows: (1) 84.5% of the students responded to the survey are regularly exercising to mete their heal thand 44.8% of them are doing something to manage stress. (2) 28.9% of the students are smDking, 43.3% of them mr drinkin2, 5% of them are taking adhesives, 6.5% are taking stimulants, and 4.5% of them are taking analgesics. (3) while self-eHcacy of the studerlts and health interests of their parents are positively related to health promuting behaviors, they are negatively related to health risk behaviors.

역류식 충진탑에서 수력학적인 분석과 이산화탄소의 탈착에 관한 연구

楊善惠,崔東勳,지혜미,金恩貞,金彰昊 동아대학교 환경문제연구소 1996 硏究報告 Vol.19 No.1

This study was carried out to interpret hydraulic behavior and CO₂gas desorption in countercurrent packing tower which packed 50 mm plastic Hiflow-ring. The results are as follows: 1. To compare with conventional packing, 50mm Hiflow-ring could save energy because of low pressure drop under high load. 2. As relative error between calculated value and investigated value was less than 6% in the loading point and flooding point we found that we can predict results mathematically which occurres in the packing tower. 3. The unique magnituteds of packing which was used are as follows. C_(L) = 2.1×10^(-4), n = 0.787 so we can predict efficency which occurres.

정맥주입 전문간호사가 삽입한 말초삽입형 중심정맥관(PICC) 사용 결과에 대한 후향적 분석

박정윤,박광옥,백미경,김세라,권혜리,양수진 대한기초간호자연과학회 2004 Journal of korean biological nursing science Vol.6 No.1

Background : Intravenous(Ⅳ) access is becoming an increasingly important part of health care today. The current drive for clinical effectiveness and cost-effective health care serves to increase the need for reliable vascular access. Venous access devices were developed to overcome problems associated with limited peripheral access and frequent venipuncture in patients with long-term therapy. Although the peripherally inserted central catheter(PICC) have become popular during recent years in USA, its procedure is rare in Korea. Purpose : The goal of this study was to analyze the PICC inserted patient data by Ⅳ CNS intervention. Method : A Total of 62 PICCs were inserted into 51 patients by the Ⅳ CNS during a 10-month period form November, 14, 2002, to October 2, 2W2. Data was obtained retrospectively through chart review. Result : The patient population included 34(54.8%) men and 28(45.2%) women, with a mean age 50.6 years. The main indication for PICC placement was to access vein in poor peripheral venous status(40.3%). The mean served interval for PICC insertions was 16.7 days(range, 2~61 days). The reasons for removal were completed therapy in 18 cases(29.0%), patient death in 13 cases(21.0%), and mechanical or functional PICC problem in 10cases(16.1%). The three PICCs removed for presumed infection, and one had only positive tip cultures(0.2%). Conclusion : PICCs are rapidly growing popularity and required an extended course of Ⅳ therapy.

숙명박물관 브랜드 프로모션을 위한 통합적 브랜드 개발 -2D, 3D, 4D 디자인 프로세스를 중심으로-

길혜경,김보현,오정은,이서연,이지원,이진민,장미정,이성애 숙명여자대학교 산업디자인연구소 2017 숙명디자인학 연구 Vol.24 No.-

본 연구는 여성생활사 중심의 유물 박물관인 숙명박물관의 인지도와 브랜딩의 문제를 해결하기 위해 브랜드·스페이스·마케팅을 활용한 통합 브랜드 개발 프로세스를 제안하는데 목적이 있다. 아울러 본 연구는 박물관의 브랜드를 프로모션하고 그래픽, 제품, 공간의 통합 브랜드를 구축하는 일련의 프로세스를 밝히는데 목적이 있다. 이에 본 연구의 시간적 범위는 2017년 3월부터 6월까지 총 15주간 숙명여대 환경디자인학과 <브랜드·스페이스·마케팅>수업에서 진행된 수업의 결과물로서 4개 팀 중, 1개 팀의 작업물로 한다. 본 연구의 대상적 범위는 ‘숙명여자대학교 숙명박물관'의 2D~4D까지의 전반으로 설정한다. 그 결과, 제품부터 공간까지 숙명박물관의 통합된 브랜딩은 일 관성과 객관성, 스토리성을 얻을 수 있었다. ’숙명박물관'은 학교의 박물관이라는 장점을 극대화시켜 가치와 스토리를 부여하고 하나의 브랜드로 리뉴얼했다는 점에서 의의가 있다. 또한 향후 보편적인 박물관들의 차별화된 브랜드 개발의 참고자료로 활용될 수 있을 것으로 기대하며 브랜드 개발에 있어서 G·I, P·I, S·I의 통합 브랜드 메뉴의 기초 자료로 활용될 것으로 사료된다.

Elevated extracellular calcium ions promote proliferation and migration of mesenchymal stem cells via increasing osteopontin expression

Lee, Mi Nam,Hwang, Hee-Su,Oh, Sin-Hye,Roshanzadeh, Amir,Kim, Jung-Woo,Song, Ju Han,Kim, Eung-Sam,Koh, Jeong-Tae Nature Publishing Group UK 2018 Experimental and molecular medicine Vol.50 No.11

<▼1><P>Supplementation of mesenchymal stem cells (MSCs) at sites of bone resorption is required for bone homeostasis because of the non-proliferation and short lifespan properties of the osteoblasts. Calcium ions (Ca<SUP>2+</SUP>) are released from the bone surfaces during osteoclast-mediated bone resorption. However, how elevated extracellular Ca<SUP>2+</SUP> concentrations would alter MSCs behavior in the proximal sites of bone resorption is largely unknown. In this study, we investigated the effect of extracellular Ca<SUP>2+</SUP> on MSCs phenotype depending on Ca<SUP>2+</SUP> concentrations. We found that the elevated extracellular Ca<SUP>2+</SUP> promoted cell proliferation and matrix mineralization of MSCs. In addition, MSCs induced the expression and secretion of osteopontin (OPN), which enhanced MSCs migration under the elevated extracellular Ca<SUP>2+</SUP> conditions. We developed in vitro osteoclast-mediated bone resorption conditions using mouse calvaria bone slices and demonstrated Ca<SUP>2+</SUP> is released from bone resorption surfaces. We also showed that the MSCs phenotype, including cell proliferation and migration, changed when the cells were treated with a bone resorption-conditioned medium. These findings suggest that the dynamic changes in Ca<SUP>2+</SUP> concentrations in the microenvironments of bone remodeling surfaces modulate MSCs phenotype and thereby contribute to bone regeneration.</P></▼1><▼2><P><B>Bone formation: released calcium could stimulate stem cells</B></P><P>Studies with mouse cells and bone samples indicate how calcium ions released during the normal turnover of bone promote the supplementation of stem cells needed to make new bone during routine “remodeling” and regeneration after injury. Our bones are degraded and remodeled continuously, requiring the controlled supplement of stem cells that create bone-forming cells called osteoblasts. Jeong-Tae Koh and colleagues at Chonnam National University, Gwangju, South Korea, exposed the relevant stem cells to increased concentrations of external calcium ions. This promoted cell proliferation and migration that allow the cells to support new bone formation. The research suggests this effect on stem cells may be achieved by calcium ions released directly from bone as it is naturally degraded. The findings may help researchers develop new ways to encourage bone regeneration after injury and surgery.</P></▼2>

Horseshoe Appliance를 이용한 Ⅲ급 부정교합의 교정적 접근

한지혜,김재곤,,백병주,양연미,서정아 大韓小兒齒科學會 2005 大韓小兒齒科學會誌 Vol.32 No.4

성장기 아동의 Ⅲ급 부정교합의 치료에는 많은 악기능 정형장치가 사용되어 왔으며 다양한 형태로 변화하여 발전되어 왔다. Horseshoe appliance는 Schwarz에 의해 소개된 장치로서 elastic의 견인력으로 장치의 free sliding 효과를 통해, 하악와와 과두의 관계를 재정립시켜, 악골 주위의 연조직이나 muscle matrix와 조화되는 새로운 위치에 하악골을 repositioning시켜 악골관계를 개선시킬 수 있다. 또한 하악의 후하방 회전 효과를 극소화시켜 전안면고경의 증가를 방지할 수 있고, 구외 장치에 비해 환자의 협조도가 좋다. 저자들은 전치부 반대교합을 주소로 전북대학교 치과병원 소아치과에 내원한 Ⅲ급 부정교합 환자에게 Horseshoe appliance를 사용한 결과 하악골에 대한 상대적인 상악골의 전방 성장과 교합평면의 반시계방향 회전, 상악 전치의 순측 경사와 하악 전치의 설측 경사로. 3개월 내에 전치부 반대교합이 해소되는 효과를 얻었다. The Horseshoe appliance was introduced by Dr. Schwarz, and it is used to correct sagittal relationships by elastic force in class Ⅲmalocclusion.It minimizes the increment of lower anterior facial height and allows the mandible to be repositioned harmoniously with the soft tissue and muscle matrix of the jaw. It has the advantages of better patient cooperation, easier construction, and more effective modification. In the patients who were treated with Horseshoe appliance, forward growth of maxilla and counterclockwise rotation of occlusal plane with labioversion of maxillary incisors and linguoversion of mandibular incisors were obtained Minimum downward and backward rotation of mandible was accepted, so increasing of lower anterior facial height was minimized.

건강장애 학생이 겪는 어려움과 지원 방안에 대한 질적 연구

박은혜,김미선,김정연 국립특수교육원 2005 특수교육연구 Vol.12 No.1

기존의 특수교육대상학생들 외에도 만성질환으로 인한 건강장애를 가진 학생들이 최근 특수교육진흥법의 특수교육대상자로 추가되었다. 이러한 학생들과 그 가족들이 겪는 교육적 어려움과 바람직한 지원방안에 관한 국내 연구는 아직까지 많이 이루어지지 않은 상태이다. 이에 본 연구는 소아암, 당뇨, 신장장애, 천식 등을 가진 학생들의 부모님을 중심으로, 의료진, 교사, 학생 본인들에게 만성질환으로 인한 어려움들과 원하는 지원방안에 대하여 면담하고 이를 질적 연구방법으로 분석하여 그 결과를 제시하였다. 연구 결과 건강장애학생들은 질병치료과정에서 겪는 어려움 외에도 학교생활과 관련하여 교사, 또래관계, 학업 지체 등 여러 가지 어려움을 겪고 있었다. 이러한 문제점을 해소하기 위하여 교사와 또래에 대한 교육, 교사와 병원 및 부모간의 적극적인 의사소통과 협력, 학교교육체계 내에서 이러한 학생들을 위한 별도의 교육서비스 제공 및 인식 제고 등이 필요할 것으로 보이며, 무엇보다 이러한 학생들의 교육과 학교생활 관리에 대한 명확한 지침을 단위학교나 교육청별로 수립하여 시행하도록 하는 것이 바람직할 것으로 전망된다. Recently, students with health impairment are included in the legal recipient group of special education. Few studies about their unique difficulties and support needs in relation to school life, were reported in Korea. In this study, we interviewed parents, teachers, and small number of students themselves and medical staff about the difficulties and support needs of students with health impairments. Target students are students who have cancer, diabetes, asthma, or a kidney disorder. Results revealed that the students experienced many difficulties such as problems related to school absence, peer relationship, teacher attitude and psychological issues. Support needs were identified in areas such as teacher/peer orientation, school-hospital cooperation, academic support for absent days, and developing school district guidelines about the educational practice for these children.

국내의 치매관련 간호연구논문 분석

김혜영,홍춘실,오경옥,이선영,정현숙,이지혜,남미라 충남대학교 간호과학연구소 2002 충남대 간호학술지 Vol.5 No.1

The purpose of this study was to analyze the trends of korean nursing research on dementia and to suggest the direction of future research. A total of 52 nursing research articles published from 1992 to 2001 were selected for this study. These articles were analyzed in a systematic way including time and source of publication, design of research, type of subjects, variable and tool of measurement, intervention outcome of experimental research, and theme of qualitative research. The results were as follows : 1. The nursing research about dementia has appeared since 1992 and increased rapidly since 1998. 2. Eighteen of 52 studies were composed of dissertation of graduate school, and the research designs were mostly quantitative. There were 36 nonexperimental research, 11 experimental research, and 5 qualitative research designs. 3. The subjects of studies were mostly the caregivers of dementia patients as 33 of 52 studies. 4. Most measurement instruments used for research were developed by researcher him/herself, or redesigned and translated into korean as the original foreign version was used. 5. In correlational research, the trend was to study physical conditions in relation to activities of daily living and functional status in dementia patients and psychological conditions in relation to burden, quality of life, depression, and stress in their families. 6. 2 methodological research were development of assessment tool of dementia patients in community, and assessment of burden of caregiver. 7. In experimental research, subjects were all dementia patients, and interventions were music therapy(5), light therapy(2), education program, cognitive stimulation training, validation therapy, hand massage, reminiscence, horticultural therapy, and art therapy. 8. Theme of qualitative research was all caring experience of family. There were 3 phenomenologic methodology, l ethnography and l case study. Based on these findings, the following recommendations were made: 1. It' s necessary to develop a reliable and valid instrument to measure the characteristics of dementia patients and family caregivers of dementia patients. 2. Experimental study should be repeated to prove the effect of intervention for dementia patients and their family.