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일측성 질폐쇄 및 동측 신장 무발생을 동반한 중복자궁 2예
윤일영,여소진,김형문,김정식,김태희,이해혁,남계현,이권해,김준모,김민의 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2
Uterus didelphys with unilateral obstructed hemivagina and ipsilateral renal agenesis usually presents after menarch with progressive abdominal pain during menses secondary to hematocolpos, and indeed a very rare congenital anomaly due to Mullerian duct malformation. An accurate and prompt diagnosis is of importance to permit treatment and to assure the future fertility of the patient. Pelvic ultrasound, physical examination and pelvic MRI established a diagnosis of hematometracolpos secondary to uterus didelphys with unilateral imperforate hemivagina. An incision in the vaginal septum allowed drainage of the hematocolpos, providing relief of the patients symptoms. We report two case of uterus didelphys with obstructed hemivagina with brief review of the literature.
오영애,하귀현,박인경,김미향,김미정,김미경,정자림,이명숙,김순동 대구효성가톨릭대학교 식품과학연구소 1992 식품과학지 Vol.4 No.-
This paper showed the summarization of the preservative method of wild vegetables in the house and the precessing method of Japanese pickles. The preservative methods of wild vegetables were explained devided into long, short term, fresh state, heat treatment and drying. Salt, soybean fermented sauce, soybean fermented paste, lees of refined rice wine and residue in the preparation of bean curd were used as the materials of Japanese pickles.
정경수,김혜경,김희수,김계양,곽영숙,김학범 충남대학교 약학대학 의약품개발연구소 1993 藥學論文集 Vol.9 No.-
As a result of extensive research efforts on the oriental medicinal herbs, some of their interesting biological activities have been elucidated. In the present study, antifatigue effects of two natural food supplements consisting of oriental herbs, Vital and Vigilor, were investigated using the ICR mice. The mice were fed with antibiotic-free normal mouse feed containing Vital or Vigilor for 14,28, or 31 days and then subjected to forced swim tests. In a test carried out in melting-ice water, Vital and Vigilor significantly increased the exhaustion times of the 28 day-fed mice by 26.9 % (p < 0.01) and 16.2% (p < 0.05), respectively. However, in the other test performed at 15±0.5℃ using 31 day-fed mice, Vigilor failed to increase the exhaustion time significantly (at p< 0.05), while Vital showed antifatigue effect by increasing the swimming time by 29.9% (p<0.01). Neither of Vital nor Vigilor exerted antifatigue effects in a swim test carried out on day 14 after the initiation of feeding. These results suggest that Vital and Vigilor exhert antifatigue effets when administered for a sufficient period of time by enhancing the health of the host animals.
한국판 Edinburgh Postnatal Depression Scale의 임상적 적용
김용구,허지원,김계현,오강섭,신영철 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.1
Objectives : The EPDS (Edinburgh Postnatal Depression Scale) is a lO-items self-report scale designed as a specific instmment to detect postnatal depression by Cox et al. (1987). This study was to determine the optimal cut-offpoint ofthe K-EPDS for postpartum depression in Korea. Methods : The 239 pregnant women assessed their own psychiatric features with the Korean version of the Edinburgh Postnatal Depression Scale (K.-EPDS), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Rosenberg Self-Esteem Scale (RSES) and Marital Satisfaction Scale (MSS) at 6 months ofpregnancy, 1 week after delivery, and 6 weeks after delivery. Subjects above 9 points of K-EPDS at 6 week after delivery were interviewed with Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) to confirm postpartum depression. Results : The prevalence of postpartum depression was 12.6% (30/239 pregnant women) in our study. The total scores of K-EPDS at 6 weeks after delivery were higher significantly than those of nonnal group. The score gap of K-EPDS between the depressed pregnant group and the normal pregnant group was increased after the delivery. However, there were no differences in the epidemiological characteristics and the BDI scores at 6 weeks after delivery between groups. Using the AUC (area under the curve), the optimal point to assess the postpartum depression was revealed as 6 weeks after delivery (AUC=85.8%) or 24 weeks of pregnancy (83.7%). The cut-offpoint of K-EPDS to detect postpartum depression among pregnant women was 9/10score of K-EPDS (AUC= 81.8%). Conclusion : In the K-EPDS, cut-off score of 9/10 was optimal to assess the postpartum depression, and K-EPDS at 6 weeks of delivery was more useful than any other point of time. K-EPDS administrated during pregnancy may be a useful tool to find the vulnerability on the postpartum depression.
Paclitaxel 및 Apo-2L/TRAIL이 자궁경부암 세포주 아포토시스에 미치는 영향
김주영,남계현,김태희,이권해,이해혁,배동한 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.2
Objective: TRAIL(also called Apo-2L) is a member of the tumor necrosis factor(TNF) family of cytokines which induces apoptosis cell death in a variety of tumor cell lines. It mediates its apoptotic effects through one of two receptors, DR4 and DR5, which are members of the TNF receptor family, and whose cytoplasmic regions contain death domains. TNF and Fas ligand induces apoptosis in tumor cells; however, their severe toxicity toward normal tissues hampers their application to cancer therapy. We examed if paclitaxed and/or Apo-2LTRAIL induces apoptosis of cervical cancer HeLa, SiHa, ME-180, and CaSki cells. Mehods : We have demonstrated that paclitaxel and Apo-2L/TRAIL induces apoptosis of cervical cancer HeLa, SiHa, CaSki and ME-180 cell lines in a dose-dependent manner. HeLa, SiHa, ME-180 and CaSki were obtained from American Type Culture Colection. Recombinant Human TRAIL(Chmicon). DR4 and DR5 were purchased from Santa Cruz. Paclitaxel, MTT assay Kit, Acridine orange and Ethium bormide were purchased from Sigma. HeLa and SiHa were grown in DMEM. ME-180 and CaSki were grown in RPMI. Tripan blue stain and MTT assay were done for cytotoxicity. Annexin V-FITC and PI(propidium iodide) flowcytometry for apoptosis assay. DR4 and DR% were expressed by Western Blot. Fluorescent Microscopy used Acridine orange(AO) and Ethium bromide(EB). Results : Importantly, concurrent treatment of cervical cancer cells with paclitaxed and Apo-2L/TRAIL induces significantly more apoptosis than Apo-2L/TRAIL alone. Conclusion : We need further studies which reveals possible therapeutic potential in the women with cervical cancer by suing Apo-2L/TRAIL.
김철호,이계영,심영수,김건열,한용철,한성구,정희순,임정기,박재형 대한내과학회 1988 대한내과학회지 Vol.35 No.3
Unilateral pulmonary vein atresia is a rare congenital disease and is frequently associated with intracardiac anomalies. It is usually diagnosed in childhood and is very rarely diagnosed in adulthood. A case of unilateral pulmonary vein atresia in a 20-year old female is de- scribed. The relevant findings were symptoms of exertional dyspnea, roentgenographic evidence of decreased lung volume, increased interstitial infiltration with septal lines in the involved side (right), and aoscence of blood flow in a radionuclide perfusion scan. Pulmonary angiography showed an extremely small right pulmonary artery and thining of the peripheral branches, and nonvisualization of the draining pulmonary veins. Bronchial arteriography showed rommunication between the bronchial artery and the right pulmonary artery and it was drained to the left pulmonary artery. Cardiac catheterization showed no intracardiac anomaly. The right bronchography was normal; pulmonary function studies showed a pure restrictive pattern and markedly in creased physiologic dead space. MRI showed no visible right pulmonary vein.
김우식,염경호,이계영 연세대학교 산업기술연구소 1986 논문집 Vol.18 No.1
A Study on the extraction of uranium(VI) was perfomed through an immobilized liquid membrane containing D₂EHPA carrier. Hydrogen ion concentration was the most predominant factor in the extraction of uranium(VI) and the extraction efficiency reached the maximum value when pH's of the feed and product solution were 2.5 and 1.0 respectively. Another operation conditions were feed and carrier concentration. The flux was reached a limiting value at feed uranium(VI) concentrations higher than 200mg/ℓand was decreased with more 15 vol% carrier concentration.
인공 산성비 용액 함침 및 경사평면법에 의한 옥외용 실리콘 고무의 열화 특성 평가
김정호,정규원,유영식,양계준,박용관 成均館大學校 科學技術硏究所 1999 論文集 Vol.50 No.1
We investigated the effect of acid rain on the surface aging, and resistance to tracking and erosion of silicone rubber materials : First, we measured the contact angle, SEM, EDX, and weight reduction to investigate the surface aging caused by immersion in the artificial acid rain solution. From the results of a series of experiments, we concluded that the acid rain attacked the base polymer of the surface, and lead to the depolymerization. Second, we adopted Inclined-Plane Method to measure the resistance to tracking and erosion of silicone rubber, and rather not observably affected the immersed specimen in the tracking resistance than in the erosion resistance.