대학교 신입생의 특성에 관한 실태조사(Ⅱ) : 1995학년도 조선대학교 신입생을 대상으로 1995 chosun University Entrants

조용래,박상학,김상훈,표경식,김학렬,김양옥,김기순,박종 조선의대 1995 The Medical Journal of Chosun University Vol.20 No.2

두개강내 정맥기형들과 동반된 안와내 해면상 혈관종 1례

조도상,송준혁,김명현,박향권,김성학,신규만,박동빈 대한신경외과학회 1998 Journal of Korean neurosurgical society Vol.27 No.6

상 요추 추간판 탈출증의 수술적 치료

조태현,송준혁,김명현,박향권,김성학,신규만,박동빈 梨花女子大學校 醫科大學 醫科學硏究所 2000 EMJ (Ewha medical journal) Vol.23 No.3

Objectives : Lumbar disc herniations at the L1-L2, L2-L3, and L3-L4 level are rare. The purpose of this study is to observe the variable clinical finding of upper lumbar disc herniations and to provide proper treatment modality. Patients and Methods : Between 1998 Jan. and 1999 Dec., seventeen patients with upper lumbar disc herniations who were undergone surgery in our institute were retrospectively evaluated. Patients were evaluated based on following factors : age, sex, aggravating factor, symptoms and signs type of disc herniation, type of surgery, and outcome of post-surgery. Results : The incidence of lumbar disc herniation at the level of L1-2, L2-3 and L3-4 is 6.1% with declining frequency as the level ascends. The peak age incidence is 6th decade in both sex. Preoperative symptomes and signs are variabe. In sixteen cases, posterior approach was done. In these cases, twelve cases were performed microscopic partial hemilaminectomy, and four cases with spinal stenosis were performed total laminectomy and posterior screw fixation with bone fusion. In one case, lateral extracavitary approach was done. In results of operation, fourteen cases showed more than good grade(82%). Conclusion : The age incidence of lumbar disc herniations at the level of L1-2, L2-3 and L3-4 older than lumbar disc herniations at the lower level of L4-5 and L5-S1. The signs and symptoms are variable. In our cases, most of the patients were performed posterior approach with microscopic partial hemilaminectomy except the patients combined spinal stenosis. One case was performed a lateral extracavitary approach because the risk of the cord and cauda equina injuries. The prognosis of upper lumbar disc herniations after treatment with only microscopic partial hemilaminectomy and diskectomy is comparable with the prognosis of lumbar disc herniations at the lower level.

호박식초의 개발

조학래,허성호 동의공업대학 1998 論文集 Vol.24 No.1

In developing pumpkin vinegar, the cabohydrates of ripe pumpkin were hydrolyzed with hydrolyzing enzymes such as Termamyl, Viscozyme, Rapidase and Dextrozyme, using the substrates of alcohol and acetic acid fermentation. The sliced pumpkin was heated for 1 hour at 110℃, then crushed. The reducing sugar concentration 11.2∼11.9% of crushed pumpkin was acquired by the enzymatic hydrolysis reaction for 24 hours that the added enzymes concentration were 0.3∼0.5% to total pumpkin volumes at 50℃. In ethanol fermentation of pumpkin hydrolysate with Sacchromyces cerevisiae. optimum reducing sugar concentration of the hydrolysate adjusted by adding dextrose was revealed as 20%. In this condition the ethanol concentration of the hydrolysate was reached 12.0% by cultured for 7days at 30℃. The pumpkin hydrolysate adjusted to ethanol concentration 6.0% with water was inoculated with Acetobacter aceti and cultured statically for 30days at 30℃. The maximum acidity 6.5% of the solution was achieved.

액체막법에 의한 중금속이온의 분리 및 회수

曺文換,丁學鎭,이상인,金振浩,金始中 江原大學校 附設 環境硏究所 1994 環境硏究 Vol.11 No.-

거대고리 리간드는 금속이온과 선택적으로 결합하는데, 이를 이용하여 에멀젼 액체막을 통한 금속이온의 이동에 관하여 연구를 수행하였다. 금속이온은 유기층에 있는 운반체에 의하여 source phase에서 receiving phase으로 이동한다. 운반체로는 거대고리 리간드인 DBN_(3)O_(3)를 사용하였다. 여기에서 에멀젼 액체막을 통한 금속이온의 이동에 관한 요인과 어떤 금속이온의 선택적 분리에 관하여 검토하였다. 금속이온과 거대고리 리간드 그리고 금속이온과 receiving phase내에 있는 음이온에 대한 안정도 상수를 금속이온의 선택적 이동에 대한 척도로 조사하였다. 납이온이 혼합 용액에서 다른 금속이온보다 높은 이동속도를 나타내었다. Receiving phase내의 음이온이 금속이온의 이동에 중요한 역할을 한다. Receiving phase내에 있는 NO_(3)^(-)을 S_(2)O_(3)^(2-) 대치하면 이동량이 증가함을 보였는데 이는 Pb^(2-)-S_(2)O_(3)^(2-) 상호작용이 Pb^(2+)-NO_(3)^(-) 상호작용보다 크기 때문이다. Macrocyclic ligand has been know to selectively bind with metal ions so that ability applied for the transport of metal ions across the emulsion liquid membrane in this study. The metal ions are transproted from the source phase to the receiving phase by the carrier of the organic phase. Several factors involved in the transport of metal ions acrose the emulsion membrane we reported here and these factors proveided the informations for the selective seperation of some metal ion. Stability constants for cation-macrocyclic ligand and metal ion-anion receiving phase interaction are examined as parameters for the prediction of metal ion transport selectivities Pb^(2+) was transported higher rates than the other metal ions in the mixture solution. The interaction of metal ion to anion in receiving phase is important. S_(2)O_(3)^(2-) in replacement of NO_(3)^(-) in the receiving phase enhances the transport of pb^(2-) since Pb^(2-)-S_(2)O_(3)^(2-) interaction is greater than Pb^(2+)-NO_(3)^(+) interaction.

미생물을 이용한 페놀 폐수지처리에 관한 연구

박상헌,심학보,이수구,서성조 서울산업대학교 산업대학원 1992 大學院論文集 Vol.1 No.1

본 연구는 혼합 미생물을 이용한 페놀 함유폐수의 생물학적 처리에 관한 연구로서, 높은 페놀 농도에서의 이를 분해시킬 수 있는 균주를 개발하고 페널 함유폐수의 효과적인 처리를 위한 실험연구이다. 각종 공장폐수, 슬러지, 토양 등 40여종의 시료로부터 페놀 분해균을 선별하였으며, 페놀농도를 단계적으로 높여 미생물을 적응시킨 결과, 페놀농도 1,000ppm의 높은 농도에서도 잘 증식하며 페놀을 효과적으로 분해시킬 수 있었다. 혼합 미생물을 분리 동정한 결과, 우점종은Pseudomonas PI인 것으로 나타났다. 회분식 실험에서 초기 페놀농도, 균체량 및 glucose 농도 등을 변수로 실험하였느데, 페놀 분해속도는 시간에 따라 증가함을 나타내었다. 또한 페놀이 완전 제거되는데 소요되는 시간은 초기 페놀 농도에 비례하였으며, 균체 주입량에 다른 초기 MLSS농도의 대수식으로 나타낼 수 있었다. 연속식 활성 슬러지법에 의한 실험에 있어서, 본 실험조건에서 페놀이 완전 제거되는데 필요한 반응기내의 체류시간은 유입 페놀농도 500ppm인 경우 20시간이 소요되는 것으로 나타났다. This investigation was carried out to study the biodegradation of phenol in wastewater using mixed microorganisms. The mixed clutures of phenol degrading microorganisms were selected from various sources such as industrial wastewaters, sludges and soils. The mixed cultures could be adapted to high concentration of phenol by increasing the phenol concentration step by step. The phenol was degraded easily even up to 1,000ppm of phenol using these microorganisms. The predominant bacteria was isolated and characterized as Pseudomonas PI. In a batch system, the removal rate of phenol increased with time due to the lag time of microorganism adapation. The duration time during which phenol could be completely removed was linearly proportional to the initial phenol concentration. And the duration time(td) could be expressed as a funtion of logarithmic initial MLSS concentration(x) as follows. td=?? [8.68-In(x)] In a continuous system, the required residence time to remove phenol completely was found to be 20 hours and 35 hours 500 ppm and 800 ppm of influent phenol concentrations, respectively.

이상형 스테인레스강의 크롬질화물 석출과 상 방위관계 연구

최병학,김진우,고석민,조용석,김상식,이재현 국립7개대학공동논문집간행위원회 2002 공업기술연구 Vol.2 No.-

Microstructures in the directionally solidified duplex stainless steels were investigated in order to understand the effect of nitrogen addition and its precipitation in the α phase. It was found that the addition of nitrogen causes the formation of fine precipitates in α matrix and segregation phases of nitrogen in the α/γ interface. Both the fine precipitates and the segregation phases were identified as CrN(fcc, a=4.18Å), as a coherent phase related to the α-bcc matrix with crystal relationship of (200) CrN//(01￣1)α and (1￣1￣1)CrN//(3￣2￣1)α.

백서의 복강내에 투여한 Mitomycin-C-Polyglycolic acid 제형이 장기에 미치는 영향에 관한 연구

송규상,강대영,최정목,노승무,정경수,오정연,김진향,양준목,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

To evaluate the in-vivo effects of mitomycin-C-polyglycolic acid composite(MMC-PGA) the disk: shaped composite were implanted into the peritoneal cavity of the Sprague-Dawley rats. The pathologic changes were examined at various time points up to 12 weeks. Initially the soft tissue around the inserted disks showed capillary congestion at 3 days. Inflammatory infiltrates with foreign body giant cells appeared from the 2nd week and reached peak response at 6-8 weeks. These reaction diminished prominently at 12 weeks. No specific pathologic change was found in the liver, the kidneys, and the heart. The above results suggest that the MMC-PGA composite can serve as a new device for intraperitoneal chemotherapy of various types of cancers.

심근의 전기적 및 기계적 성질에 미치는 부자 부타놀 분획의 효과

정학기,조성일,엄대용,이상돈 중앙대학교 의과대학 의과학연구소 1981 中央醫大誌 Vol.6 No.3

In order to investigate the action mechanism of Aconiti tuber butanol fraction (ABF) on the isometric contraction of cardiac muscle cells, transmembrane potential and action potential which was picked up by 3 M KCI glass microelectrode were recorded at the same time in rabbit papillary muscle preparations from right ventricles. The isometric contraction and action potential were recorded from the papillary muscles superfused in the control Tyrode solution and ABF Tyrode solution in which the preparations were kept beating (lHz) for about 30 minutes to get stable data. The resting membrane potential, amplitude of action potential, the amplitude of overshoot potential, time to repolarize 60%, 90% of the amplitude of action potential and the first derivatives of potential variations in plateau and repolarization were analyzed from recorded transmembrane action potential control Tyrode solution and ABF (5×10^-4~2×10^-3gm/ml)-Tyrode solution in wihth howesd about in 150% of positive isotropic effect compared with those controls. The following results were obtained to compare those parameters in the controls and in the ABF-Tyrode groups: 1. ABF shortened the time-to-peak tension from the value of 155 ms in the controls to 138 ms in. the experimental groups (0.05<p<0.1). 2. ABF showed almost no effects on resting membrane potential, amplitude of action potential and amplitude of overshoot potential. 3. ABF significantly shortened the time to repolarize 60% and 90% of the action potential amplitudes from 209 ms and 271 ms in the controls to 186 ms and 237 ms in the ABF-treated groups (0.05<p<0.1). Therefore the maximum values of the first derivatives of potential variations (-Vmax) in the. plateau phase and repolarization phase were also significantly increased from 16.5V/sec in the control groups to 18.7V/sec in the ABF-treated groups. The above results could be interpreted as that the effect of ABF on cardiac muscle was due to enhancement of slow inward current, especially calcium current.

Clinical Analysis for Stereotatic Aspiration and Thrombolysis of Spontaneous Intracerebral Hemorrhage

황승균,조도상,김성학,박동빈 이화여자대학교 의과대학 2005 EMJ (Ewha medical journal) Vol.28 No.1

목적 : 저자들은 자발성 뇌출혈 환자에서 뇌 정위적 혈종 배액술 및 용해술의 경험을 분석하여 이 방법의 유용성, 안전성 및 예후인자 등을 평가하고자 한다. 방법 : 기질적인 원인 혹은 혈액 응고성 질환이 없으면서 천막상부 자발성 뇌출혈 용량이 25ml이상 되는 11명의 환자를 대상으로 하였다. 이 중 글라스고우 혼수계수가 5이하인 환자는 대상에서 제외하였다. 컴퓨터 전산촬영 유도하에 카테터를 자발성 뇌출혈에 정위적으로 유치하고 유로키나제를 주입한 후 현종을 흡인하여 제거하였다. 이 과정은 처음 혈종 용량의 절반 이하가 될 때까지 6시간 간격으로 반복하였다. 예후인자를 분석하기 위하여 환자를 두 개의 집단 즉, 글라스고우 결과계수가 4이상의 양호한 집단과 글라스고우 결과계수가 4이하의 불량한 집단으로 나누어 서로 비교분석 하였다. 결과 : 환자들의 평균연령은 59.8세이고, 초기 혈종의 용량의 범위는 15에서 72ml였다. 혈종 용량의 감소비율은 평균 74.2%였다. 시술 후 6개월 추적관찰결과, 56(50.9%)명의 환자는 양호한 회복을 보였고, 29(26.3%)명의 환자는 의존적인 상태였으며, 10(9.0%)명의 환자는 식물인간상태로 유지되었다. 그리고, 15(13.6%)명의 치료도중 사망하였다. 주요한 중요 예후인자는 젊은 나이, 적은 혈종용량, 높은 글라스고우 혼수계수 및 재출혈, 기존질환, 합병증이 없는 경우였다. 결론 : 자발성 뇌출혈 환자에서 뇌 정위적 혈종 배액술 및 용해술이 혈종의 용량을 감소에는 안전하고 효율적인 방법임을 알 수 있었다. 그리고, 불량한 예후인자를 가지고 있는 자발성 뇌출혈 환자는 주기적인방사선학적 검사와 더욱 세심한 시술이 필요할 것으로 사료된다 그리고, 앞으로 연구는 적절한 용해제 용량의 평가와 치사율과 장해율을 감안한 정밀한 비교분석이 있어야 한다고 생각된다.