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      • 서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

        김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

        In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

      • Anti-Inflammatory and Cytoprotective Effects of TMC-256C1 from Marine-Derived Fungus <i>Aspergillus</i> sp. SF-6354 via up-Regulation of Heme Oxygenase-1 in Murine Hippocampal and Microglial Cell Lines

        Kim, Dong-Cheol,Cho, Kwang-Ho,Ko, Wonmin,Yoon, Chi-Su,Sohn, Jae Hak,Yim, Joung Han,Kim, Youn-Chul,Oh, Hyuncheol MDPI AG 2016 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.17 No.4

        <P>In the course of searching for bioactive secondary metabolites from marine fungi, TMC-256C1 was isolated from an ethyl acetate extract of the marine-derived fungus <I>Aspergillus</I> sp. SF6354. TMC-256C1 displayed anti-neuroinflammatory effect in BV2 microglial cells induced by lipopolysaccharides (LPS) as well as neuroprotective effect against glutamate-stimulated neurotoxicity in mouse hippocampal HT22 cells. TMC-256C1 was shown to develop a cellular resistance to oxidative damage caused by glutamate-induced cytotoxicity and reactive oxygen species (ROS) generation in HT22 cells, and suppress the inflammation process in LPS-stimulated BV2 cells. Furthermore, the neuroprotective and anti-neuroinflammatory activities of TMC-256C1 were associated with upregulated expression of heme oxygenase (HO)-1 and nuclear translocation of nuclear factor-E2-related factor 2 (Nrf2) in HT22 and BV2 cells. We also found that TMC-256C1 activated p38 mitogen-activated protein kinases (MAPK) and phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathways in HT22 and BV2 cells. These results demonstrated that TMC-256C1 activates HO-1 protein expression, probably by increasing nuclear Nrf2 levels via the activation of the p38 MAPK and PI3K/Akt pathways.</P>

      • Profile Index에 따른 Panelipse Ⅱ 放射線 像層의 變化

        曺哲鎬,成在鉉 慶北大學校 齒科大學 1985 慶北齒大論文集 Vol.2 No.1

        This research was made to investigate the change of the image layer and of the vertical and horizontal magnification on the Panelipse radiographic image by the control of profile index. Using the Panelipse, a series of 60 exposures were taken with the steel balls placed in the holes of the plastic model plate, and then evaluated by 4 observers. Two points were assigned for a reading of sharp, one for middling sharp, and zero for unsharp. Each ball image then could be given a total reader score of 0 to 8. The author analyzed the image layer as defined by a sharpness score of 6 or more. The resutls obtained were as follows: As the profile index was increased, the shape of the image layer was not changed, and the width of the image layer was increased, and the position of the layer shifted away from the rotation center. As the profile index was increased, the ranges of vertical and horizontal magnification was increased, especially the ranges of horizontal magnification was greater than that of vertical magnification.

      • 단백질흡착을 막는 소프트콘택트렌즈에 관한 연구

        조종수,정영일,나재운,김성호 朝鮮大學校 1997 藥學硏究誌 Vol.18 No.2

        양말단에 이크릴레이트를 갖는 폴리에틸렌글리콜 미크로마(PEG macromer)와 또한 PEG macromer와 폴리하이드록시에칠메타아크릴레이트[P(HEMA)] 혹은 폴리(하이드록시에칠메타아크릴레이트-하이드록시프로메타아크릴레이트-비닐피롤리돈)[P(HEMA-co-HPMA-co-NVP)]와 상호침투된 망상구조의 시료가 소프트콘텍트렌즈의 알부민의 흡착을 막기위하여 제조되었다. PEG macromer의 중합으로 macromer의 다관능성기로 인하여 가교된 겔이 형성되었다. P(HEMA-co-HPMA-co-NVP)/PEG IPN계 콘텍트렌즈에서 PEG분자량이 중가할수록 알부민의 흡착량은 감소되었다. 또한 IPN제조시의 PEG의 농도가 짙을수록 알부민의 흡착량은 감소되었다. PEG macromer와 IPN하기전의 P(HEMA)계 및 P(HEMA-co-HPMA-co-NVP)계의 콘텍트렌즈에 비하여 PEG macromer와 IPN함으로서 렌즈의 착용감이 훨씬 상승되었다. Poly(ethylene glycol)(PEG) macromers terminated with diacrylate groups and interpenetrating polymer networks(IPN) composed of poly(hydrowyethyl methacrylate)(PHEMA) or poly(hydrowyethyl methacrylate-co-hydroxypropyl methacrylate-co-N-vinyl pyrrolidone)[P(HEMA-co-HPMA-co-NVP)]and PEG macromer were synthesized with the aim of abtaining protein adsorption resistant soft contact lens. Polymerization of PEG macromer. Crosslinked p(HEMA)or P(HEMA-co-HPMA-co-NVP) chains were interpenetrated into the cross-linked three-dimensional networks of PEG. It was found that albumin adsorption onto the contact lens prepared by P(HEMA-co-HPMA-co-NVP)/PEG IPN decreases with an increase of molecular weight of PEG. Also, it was found that albumin adsorption onto the both contact lens decreases with an increase of concentration of PEG macromer in the IPN preparation. There are also more adequate in the biointerness for the contact lens by P(HEMA)/PEG IPN or P(HEMA-co-HPMA-co-NVP)/PEG IPN than that by P(HEMA) or P(HEMA-co-HPMA-co-NVP).

      • KCI등재

        백서에서 치아회분말과 연석고의 혼합매식술에 관한 실험적 연구:혼합 비율에 따른 비교

        조재오,여환호,김영균 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.1

        This study was performed to determine the ideal mixing ratio of toothash and plaster of Paris. The histopathologic and histomorphometric study of bone response of five implant materials, toothash(Group A), tooth and plaster mixture, mixing ratio due to weight 2 : 1(Group B), 3 : 1(Group C), 4 : 1(Group D), and plaster Paris(Group E), were performed in rat calvarial defect. No sign of extensive inflammatory reaction was defected. Newly-formed bony ingrowth occurred in all experimental groups except for group E at 12 weeks after operation. Bone was deposited directly on the surface of implant materials. The highest rate of direct bony union between implant material and newly-formed bone occurred with the group B, followed group C, D, and A.

      • 「작물별ㆍ재배유형별 표준시비량과 시비추천량」프로그램

        정호근,조재규,최칠구,김사균 한국농업정보과학회 2000 농업정보과학 Vol.2 No.1

        Generally farmers cultivate 2 or 3 crops in a year, In some cases more than 10 crops are culti-vated in a year by a farmer, These crop numbers and varieties also might be changed depending on the farmer's income based on the crop. Therefore, farmers have diHiculty in configurating the recommended for-tilizer rate for each crop. This study developed a series of user-friendly EXCEL Program to help farmers and extension specialists making decision on fertilizer rate for each crop. By using the program farmers can decide appropriate fertilizer rates based on the soil test results for each field and crop, which can improve fertilizer use efficiency. Also, this program might be useful to make a farm plan by reflerting fertilizer tost required for each field.

      • 한국産 황어의 종묘생산에 관한 연구 1. 産卵習性 및 初期生活史

        조재권,오성현,노병율,한경호,성기백,박준택 麗水大學校 産業基術硏究所 1999 産業基術硏究所 論文集 Vol.8 No.-

        강원도 양양군에 위치한 남대천과 전라남도 섬진강에 분포하고 있는 황어의 종료생산을 위한 기초자료로 産卵習性과 初期生活史에 관하여 관찰한 결과는 다음과 같다. 황어의 産卵期는 자연상태에서 3∼6月이고, 産卵은 흐르는 하천의 자갈 밑에 하였으며, 受精된 卵은 작은 자갈의 표면에 붙어있었다. 알의 크기는 2.70∼3.20㎜(평균 3.00㎜)로 油球는 없었다. 孵化는 평균 사육수온 10.60℃에서 受精 後 300시간부터 시작되었으며, 312시간만에 완료되었다. 孵化 直後의 仔魚는 전장 6.35∼6.87㎜(평균 10.67㎜)로 난황이 거의 흡수되어 後期仔魚期로 접어들며, 입과 항문이 열려있었다. 孵化 後 7∼9일째 後期仔魚는 전장 11.35∼12.30㎜(평균 11.65㎜)로 등지느러미가 생길 부분이 융기하기 시작하였다. 孵化 後 12∼13일째 개체는 전장 12.65∼13.15㎜(평균 12.80)로 이때부터 Daphnia sp.와 Brachionus plicatilis를 攝餌하였으며, 성장이 다소 빨라졌고, 脊索의 끝부분은 45°위로 굽어져 있었다. 孵化 後 43∼45일째의 개체는 전장이 19.55∼22.85㎜(평균 21.95㎜)로 모든 지느러미 줄기가 정수에 달하여 稚魚期로 이행하였다. 孵化 後 50∼52일째의 稚魚들은 전장이 21.54∼27.35㎜(평균 24.55㎜)로 몸의 형태, 체색 및 옆줄이 완전하게 형성되어 成魚에 닮아 있었다. The spawning behavior and early life history of sea rundace, Tribolodon hakonensis were studied. Spawning of T. hakonensis occurs enmasse on bottoms of stream with a spawning season of March to June. The eggs are attached to the under surface of the gravel. The eggs riped were demersal and adhesive, and their diameter were 2.70∼3.20㎜(mean 3.00㎜). Hatching was started at 300 hours after fertilization at mean water temperature 10.60℃. Newly-hatched larvae were 6.35∼6.87㎜ in total length(TL, Mean 6.65㎜), and mouth and anus were not yet opened. 4∼5 days old larvae transformed to postlarva stage and they were 10.25㎜∼11.15㎜ in TL (mean 10.67㎜). As yolk sac were nearly absorbed, mouth and anus were opened. In 7∼9 days after hatching, total length 11.35∼12.30㎜(mean 11.65㎜). The part of the fin-fold at dorsal fin became high. 12∼13 days old larvae were 12.65∼13.15㎜ in TL(mean 12.80㎜), and they fed Daphnia sp. and Brachionus plicatilis actively. In this time the growth rate slightly increased and tip of notocord was flesed on upward. Aggregate numbers of all fin rays were completed at over 19.55∼22.85㎜ in TL(43∼45 days after hatching), at which time the larvae reached the juvenile stage. 50∼52 days old larvae(21.54∼27.35㎜ in TL) were similar in body from, lateral line and color with adult.

      • KCI등재

        공동주택 현장 실험을 통한 바닥복사냉방의 성능평가

        조영흠,임재한,석호태,여명석,김광우 대한건축학회 2004 대한건축학회논문집 Vol.20 No.11

        The objective of this study is to analyze the performance evaluation of the Radiant Floor Cooling and the dehumidification system included in the integrated system may be utilized as a supplementary cooling device through field experiments. The experiments are performed to evaluate the performance of the radiant floor cooling and confirm the possibility of continuous cooling through the actual field experiments, moreover, analyze specific characters of the radiant floor cooling system according to varying the load conditions which is able to happen to field. Experiment results show that the permissible ambient temperature range was determined by cooling load calculations, and the cooling capacity was calculated from steady-state heat transfer equations. Under these conditions, experiments were performed for an actual apartment building assuming two occupants. During 80% of the cooling period, radiant floor cooling provides sufficient and continuous cooling. The results of analyzing the indoor thermal environment in the actual apartment building show that the set room air temperature is maintained while the floor surface temperature, vertical temperature distribution and PMV remain within the comfort range.

      • 스포츠參加者의 Lifestyle에 관한 要因分析

        조재호,조만태,안영필 東亞大學校附設스포츠科學硏究所 1992 스포츠科學硏究論文集 Vol.10 No.-

        The purpose of this study is to apply and test lifestyle concept in the field of sports behavior research. The AIO(Activities, Interests, and Opinions) approach is used to operationalize the lifestyle concept. Questionnaires containing 63 AIO statements are admistered to a total 600 members of a private sport club in Busan. 452 usable questionnaires were returned, resulting in a response rate of 75.3%. The sampling was chosen by the stratified random sampling Method. Analysis Method was used factor analysis to identify. The overall structure of club member's lifestyle the main result of the study : There exist eight factors representing dimensions of club member's lifestyle, there are named as sensitive of fashion, preference of Brend, Achievement, stability directed, self-confidence, Nihilism, Health-Conscious, self-affirmative.

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