서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

Anti-Inflammatory and Cytoprotective Effects of TMC-256C1 from Marine-Derived Fungus <i>Aspergillus</i> sp. SF-6354 via up-Regulation of Heme Oxygenase-1 in Murine Hippocampal and Microglial Cell Lines

Kim, Dong-Cheol,Cho, Kwang-Ho,Ko, Wonmin,Yoon, Chi-Su,Sohn, Jae Hak,Yim, Joung Han,Kim, Youn-Chul,Oh, Hyuncheol MDPI AG 2016 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.17 No.4

<P>In the course of searching for bioactive secondary metabolites from marine fungi, TMC-256C1 was isolated from an ethyl acetate extract of the marine-derived fungus <I>Aspergillus</I> sp. SF6354. TMC-256C1 displayed anti-neuroinflammatory effect in BV2 microglial cells induced by lipopolysaccharides (LPS) as well as neuroprotective effect against glutamate-stimulated neurotoxicity in mouse hippocampal HT22 cells. TMC-256C1 was shown to develop a cellular resistance to oxidative damage caused by glutamate-induced cytotoxicity and reactive oxygen species (ROS) generation in HT22 cells, and suppress the inflammation process in LPS-stimulated BV2 cells. Furthermore, the neuroprotective and anti-neuroinflammatory activities of TMC-256C1 were associated with upregulated expression of heme oxygenase (HO)-1 and nuclear translocation of nuclear factor-E2-related factor 2 (Nrf2) in HT22 and BV2 cells. We also found that TMC-256C1 activated p38 mitogen-activated protein kinases (MAPK) and phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathways in HT22 and BV2 cells. These results demonstrated that TMC-256C1 activates HO-1 protein expression, probably by increasing nuclear Nrf2 levels via the activation of the p38 MAPK and PI3K/Akt pathways.</P>

기종성 신우신염의 임상양상 및 사망위험인자

조수연,이호재,조용현,이승주 대한감염학회 2009 감염과 화학요법 Vol.41 No.1

Background : Emphysematous pyelonephritis (EPN) is an acute gas forming necrotizing infection of the renal parenchyma with high mortality. Although its incidence is relatively low, it mostly occurs in patients wiith diabetes mellitus. The aim of the study is to identify the risk factors related to mortality and assess the outcome of managements according to the radiologic classification. Materials and Methods : The clinical records of 23 patients diagnosed with EPN were reviewed retrospectively. The cases were grouped into two types on the basis of computed tomography scan. Type 1 EPN was defined as renal necrosis and gas formation with total absence of fluid content. Type 2 EPN was defined as the presence of renal or perirenal fluid in association with bubbly or loculated gas pattern. The patients' symptoms, performed investigations, and treatments were analyzed. Results : All patients had diabetes mellitus. Escherichia coli (78.6%) was the most common pathoqen in urine and blood cultures. The factors showing statistically significant differences between survivors and non-survivors were age (P=0.013), the presence of obstructive uropathy (P= 0.008), and type 1 group (P=0.030). Multivariate logistic regression showed that factor significantly related to death was age (odds ratio=1.20, 95% confidence interval 1.01-1.38, P=0.037). Conservative treatment including antibiotics and percutaneous drainage was successful in type 2 group, Overall mortality was 26.1%; all expired patients were from type 1 group. The mortality of conservative treatment and nephrectomy in type 1 group was 83.3% and 20.0%, respectively. Conclusion : These results suggest that old age is a significant risk factor for mortality in patients with EPN. Nephrectomy should be considered as the main treatment option in patients with type 1 EPN.

한국 정신장애의 역학 조사 연구[I] : 각 정신장애의 유병률

조맹제,함봉진,김장규,박강규,정은기,서동우,김선욱,조성진,이준영,홍진표,최용성,박종익,이동우,이기철,배재남,신정호,정인원,박종한,배안,이충경 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.4

Objectives : This study aims to estimate the prevalence of the DSM-IV psychiatric disorders in Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI). Methods : Subjects were selected by taking multi-stage, cluster samples of 7,867 adult household residents, 18 to 64 years of age, in ten catchment areas. Total 78 trained interviewers administered the K-CIDI to the selected respondents, from June 1 to November30,2001. Results : Total 6,275 respondents completed the interview. Some 33.5% of respondents reported at least one lifetime disorder, 20.6% reported at least one-year disorder, and 16.7% reported at least one-month disorder. The most common lifetime disorders were alcohol abuse/dependence (17.24%), nicotine dependence/withdrawal (11.19%), specific phobia (5.16%), and major de-pressive disorder (4.25%). The lifetime prevalence of substance abuse/dependence (0.25%) and schizophrenia (0.16%) was very low. Nicotine and alcohol use disorder showed very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among female than male. Conclusion : The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in distributions of psychiatric disorders across the areas and times were observed.

스포츠 가치의식에 영향을 미치는 스포츠의식에 관한 연구

조재호,조만태,안영필 東亞大學校附設스포츠科學硏究所 1998 스포츠科學硏究論文集 Vol.16 No.-

The emergence of a new phenomenon called sports value consciousness and its diversification make itself a meaningful research task, in that it demands a change of healthy human consciousness according to various social structures. The present study, therefore, aims to establish a reasonable standard of sports value consciousness as well as a new social system of value paradigms regarding all sports phenomena by revealing the consciousness patterns and related factors affecting the sports value consciousness sports activities. For this purpose, 533 subjects were chosen by the systematic stratified cluster random sampling method from among the population of athletes and leaders in high schools and universities in Pusan as of 1997. The questionnaire for this research was adopted from the studies of Niwa (1985), Uesugi (1987, 1990), Kusaka (1988), and Asanuma (1990). The original inquiry items underwent two preparatory tests for the judgment of validity and reliability before actual administration. The entire data went through χ²test, discriminant analysis to minimize Wilk's λ. The following conclusions were made from this study: 1. As to sports consciousness, the more educated and the older one was, the more one was likely to develop Recreation (or Secular) orientation. 2. Concerning sports value consciousness, the tendency toward Ascetic and Agon orientation was stronger when one was older, more schooled or one's parents had specialized occupation. As a differentiation of sports value consciousness, 60.5% belonged to Ascetic orientation, 39.5% Agon orientation, 90.6% Leisure (or Play) orientation, and 9.4% Recreation orientation. 3. In the relationship between sports consciousness and sports sense of value, such factors as the principles of discipline, training, continutiy, spiritualism, development, and concentration affected Ascetic of Agon orientation. In addition, the factors or principles of development, spiritualism, and focus on sports had an influence on Leisure or Recreation orientation.

울산광역시 외국인 투자 유치 방향

조재호 울산대학교 2003 사회과학논집 Vol.13 No.1

본 논문에서는 동북아시아의 경제협력, 울산경제의 특징, 울산과 중국간의 무역추이, 최근 외국인 투자추세를 분석하면서 울산시가 추진하고 있는 외국인 투자 유치를 통한 물류 및 서비스 중심의 산업구조로 전환하는 경제개발 전략의 한계를 지적하였다. 본 논문에서 제시하는 외국인 투자유치 방향은 제조업에 중심을 둔 거점형 해외투자유치를 적극이용하면서 동북아시아의 자원 중심적 동북아 지역 전진 기지화를 추진하는 것을 주장하였다. 따라서 울산시가 추진하고 있는 다양한 분야의 외국인 해외투자유치 보다는 한국의 대표적인 공업도시로서 제조업 중심의 비교우위가 있는 특정분야를 직접 육성하는 방향으로 울산의 장기 발전전략이 수립되어야 한다. This paper discusses the prospects for APEC, the trend of global foreign investment and the characteristics of Ulsan industries and then reviews the recent policy direction for foreign investment proposed by Ulsan city. This paper suggests that Ulsan city should develop the regional development plan based upon the Ulsan citys competitiveness on heavy-and chemical industries. This paper suggests that Ulsan citys plan should establish the foreign investment straegy aiming at the China and Russia markets under the APEC movement.

LANDSTAT 자료를 이용한 유출곡선지수의 추정

조홍제,황재호 울산대학교 2001 공학연구논문집 Vol.32 No.1

수치고도모델을 이용하여 유역의 지형학적 특성을 분석하고, LANDSAT 위성영상을 이용하여 유역의 토지피복상태를 분류한 후 유출곡선지수를 추정하였다. 특히, 우리나라는 유역의 대부분을 산림이 차지하는 피복특성이 있으므로 식생의 다중반사특성을 응용하여 산림지역을 분류하고 유출곡선지수 추정에 응용하였다. 산림지역은 식생의 건강 상태나 밀도에 따라 유출특성이 변화하는데, LANDSAT 위성영상의 다중분광자료를 사용하여 산출한 식생지수는 산림지역을 밀도나 건강상태에 따라 분류하는데 유용하였다. 또한 식생지수를 사용하여 산림지역을 분류한 후 산출한 유출곡선지수는 산림지역을 분류한 후 산출한 유출곡선지수에 비하여 감소하는 것을 확인할 수 있었다. Having analyzed the topographical quality of the basin using Digital Elevation Model and classified land uses by LANDSAT Satellite image, we estimated Runoff Curve Numbers. Most of the basins are characterized by the forest, therefore multiple reflex qualities were used to classify the forest and to estimate Runoff Curve Numbers. Because runoff changes according to the vegetative health and density, the vegetation index derived from the multispectral data of LANDSAT satellite images was useful to classify the forest by its health and density. It was observed that Runoff Curve Number decreased when the vegetation index was taken into account. In conclusion, the mulispectal image was useful to observe special quality and classification of the land.

SOL-GEL법을 이용한 강유전체 BaTiO₃박막 및 Ceramics 제조

조채룡,이수재,장민수,김호종,정세영,노동택,김성철 동의대학교 기초과학연구소 1993 基礎科學硏究論文集 Vol.3 No.1

Concentrated solution was prepared for a sol-gel process of BaTiO₃. Barium hydroxide and Ti-isopropoxide were used as the raw materials with methanol and isopropanol as solvents. Dense ferroelectric polycrystalline BaTiO₃thin films with the perovskite structure were fabricated by spin coating of the prepared concentrated solution on a few substrates. From XRD investigation, it was confirmed that tetragonal phase of polycrystalline BaTiO₃powders are formed after heat treatment above 550℃ in air and grain-oriented BaTiO₃thin films are obtained by coating of 0.06M concentrated solution on the substrates. It was observed that surfaces of thin films deposited on the substrates by our methods were formed crack-free and uniformly. The thickness of thin film which depends the concentration of the solution was 400∼900Å for 1 time coating, which was confirmed by SEM analysis. Ceramics and thin films show dielectric constant of 4600 (at 1㎑) and capacitance 300∼800㎊ (at 1㎑) at room temperature, respectively.

[논문]지구단위계획의 운용방안에 관한 연구 -부산시 용도지역 상향조정 지역을 사례로-

조재권,이성호 釜山大學校 都市問題硏究所 2004 都市硏究報 Vol.16 No.-

Longitudinal segmentation in the residential happened to civil appeals of up-zoning, so the areas needs to establish the District Unit Plan. But the characteristics of the district are difficult the control in the zoning system, implement of u-zoning. Therefore District Unit Plan needs to reflect public's opinions, to achieve the public urban of operational application of District Unit Plan. For this purpose, This study is established planning elements and surveyed two Up-zoning area of District Unit Plan and inspected priority elements, analysed each planning elements.

IIIB 병기 비소세포 폐암의 방사선치료 성적

조문준,박승호,김재성,김선영 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.2

To evaluate the effect of radiation therapy in nonsmall cell lung cancer stage IIIB, we analyzed the 23 patients diagnosed NSCLC IIIB and treated curatively with radiation therapy between September 1989 and March 1993 at the department of therapeutic radiology, Chungnam National University Hospital, retrospectively. The actuarial 1 year survival rate was 39.2%, 2 year survival rate was 2.3%, and median survival time was 10 months. The difference of survival rates by performance status, response to radiotherapy, T stage, N stage, tumor size, age, pathologic cell type, combination with chemotherapy was not statistically significant. To increase the survival time and rate of the patients with NSCLC IIIB, further study for adequate radiation fractionation and dose, combination with chemoherapy and surgery will be needed.