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Baek Seungju,Yu Dong-Yurl,Son Jun-Hyuk,Bang Junghwan,Kim Jungsoo,Kim Min-Su,Lee Han-Bo-Ram,고용호 대한용접접합학회 2020 대한용접·접합학회지 Vol.38 No.4
In this study, we investigated the effect of plasma treatment for the surface of an insert bonding metal on the prop�erties of a transient liquid phase (TLP) bonding joint for a power module. Sn preforms, as the insert bonding metal for the TLP bonding, were used with and without Ar plasma treatment. To investigate the effect of Ar plasma treat�ment, the TLP bonding for two structures of Cu-finished Si chip/Sn preform/organic solderability preservative (OSP)-finished direct bond copper (DBC) substrate (Cu/Sn/Cu), and Ni-finished Si chip/Sn preform/Ni(P)-finished DBC substrate (Ni/Sn/Ni) was performed with 1 MPa at 300 ℃ and the bonding times were 10, 30, and 60 min, respectively. After the TLP bonding, we observed interfacial reactions and formations of intermetallic compounds (IMCs) under various bonding conditions. To evaluate mechanical properties, a shear test was also performed. Compared to the TLP bonding joint that used bare Sn preforms without Ar plasma treatment, growth of IMCs at the bonding joint that used Sn preforms with Ar plasma treatment occurred faster, and the IMCs could be formed through the entire joint despite the bonding time of 10 min. Meanwhile, by increasing the bonding time, Cu6Sn5 and Cu3Sn were formed at the Cu/Sn/Cu TLP bonding joint, whereas Ni3Sn4, Ni-Sn-P, and Ni3P were observed at the Ni/Sn/Ni joint. In the case of the Cu/Sn/Cu joint, we observed that increasing Cu3Sn formation while increasing the bonding time could be beneficial to the shear strength of the joint. Further, shear strengths of the joint were not sig�nificantly changed under the bonding conditions after Ni3Sn4, Ni-Sn-P, and Ni3P IMCs were formed at the entire joint of the Ni/Sn/Ni.
한국산 독말풀에 대한연구(Ⅰ) : HPLC에 의한 Hyoscyamine 과 Scopolamine의 정량
도경삼,신민교,송호준,선중기,손인경,백승화 원광대학교기초자연과학연구소 1992 基礎科學硏究誌 Vol.11 No.3
A new method for quantitative determination of Hyoscyamine and Scopolamine in Datura stramonium L. by High Performance Liquid Chromatography(HPLC) was established. A reversed-phase system with a μ Bondapak C18 column using methanol in 0.2% aqueous phosphoric acid(40:60) with PIC A as a mobile phase was developed. Hyoscyamine and Scopolamine were detected at 254nm and the analysis was successfully carried out within 20min.
2003년 국내 중증급성호흡기증후군 진료 현황 및 문제점 분석
이진수,김은실,정문현,백제중,정선화,안주희,최영화,이선희,고철우,김성범,김민자,박승철,기현균,송재훈,최상호,김양수,이상오,조용균,박영훈,정숙인,김연숙,이흥범,손창희,장성희,정희진,김우주 대한감염학회 2004 감염과 화학요법 Vol.36 No.3
목적 : 2002년 말 중국에서 SARS가 발생한 이후 국내에서도 2003년 10월까지 총 3명의 추정환자, 17명의 의심환자가 보고되었다. 향후 추가적인 SARS의 유행이 우려되는 상황에서, 그간의 SARS 환자 진료에 있어서의 실질적인 준비사항, 진료 현황 등에 대한 조사를 통해 문제점을 파악하여, 향후 더 나은 대비가 될 수 있도록 개선점을 제시하고자 하였다. 재료 및 방법 : SARS로 의심되는 환자를 진료 경험이 있는 병원의료진을 대상으로 2003년 10월에 설문조사를 실시하였다. 설문에는 SARS 환자 진료 시의 실질적인 조치, 진료 현황, 병실, 응급실 및 외래에서의 격리 시설과 준비사항, 보건당국의 관리와 지원에 관한 사항을 포함하였다. 결과 : 대상이 되는 22개 병원 중 17개(17/22, 77.2%) 병원이 설문에 응하였다. SARS 환자를 위한 격리실은 응급실, 외래, 일반병실 및 중환자실에서 각각 9개(9/17, 52.9%), 5개(5/17, 29.4%), 15개(15/16, 93.7%), 4개(4/16, 25%) 병원에서 음압처리가 되어있지 않은 일인실 혹은 다인실이 사용되었고, 1개(1/16, 6.3%) 병원에서만 일반병실에서 음압격리실이 운영되었다. 입원환자의 진찰 시 개인보호구의 착용은 거의 모든 의료기관에서 이루어졌다. 보건당국에서 SARS지정병원의 시설 등을 사전에 확인한 곳은 1곳(1/12, 8.3%)이였고, 14개 병원(14/15, 93.3%)에서는 보건당국에 의뢰한 검사결과를 통하 받지 못하였다. 결론 : 의료기관에서 SARS 환자용 격리실뿐만 아니라 기존의 격리실 설비 등이 미흡하였으며, 특히 중환자실 및 외래의 준비가 더욱 부족하였다. 보건당국의 의료기관에 대한 종합적인 지원이 부족하였고, 병원과의 원활한 연계가 잘 이루어지지 않았다. SARS 만이 아닌 격리를 필요로 하는 질환의 적절한 진료를 위해 향후 병원 시설의 정비와 정부차원에서의 보다 구체적이고 실질적인 대책마련이 필요하다. Background : There was an worldwide outbreak of the Severe Acute Respiratory Syndrome (SARS) originated from China in late 2002. During that period three cases of suspected SARS and 17 cases of probable SARS were reported in Korea. With the concerns about the reemergence of SARS-coV transmission, it is important to be prepared for any possibility. So, this study is aimed to analysis the past measures in managing SARS and propose the amendatory plans to improve the preparedness. Materials & Methods : Questionnaires were collected among clinicians with any experience in managing the probable or suspected SARS cases in Oct. 2003. 17 out of 22 hospitals responded to the questionnaire. The contents in the questionnaire were practical activities, personal equipments, response plans, isolation facilities in emergency centers, outpatient clinics, general wards and intensive care units, and relationship with the public health department. Results : The dedicated isolation rooms in emergency centers, outpatient clinics, general wards, and intensive care units were prepared in 9 (9/17, 52.9%), 5 (5/17, 29.4%), 15 (15/16, 93.7%), and 4 (4/16, 25.0%) hospitals, respectively. Except for one hospital that newly made negative pressure room for SARS, single or multi-bed rooms without airborne infection control were used in all the other hospitals. The personal precaution principles were kept quite well in general wards. Before the designation of SARS hospital by the public health department prior evalution to see if the hospital was suitable for managing SARS was conducted in only 1 (1/12, 8.3%) hospital. The results of laboratory diagnosis were reported back in 1 (1/15, 6.6%) hospital. Conclusions : The isolation facilities which can control airborne infection were almost deficient not only for SARS but also for other respiratory transmissible diseases. For the infection control of transmissible diseases including SARS, more investment is needed on medical facilities and comprehensive support from the public health department required.
Min Ho Hwang(황민호),Jae Hee Shin(신재희),Hyo Geun Nam(남효근),Hyeong Guk Son(손형국),Seung Min Baek(백승민),Chang Min Yoo(유창민),Jeong Hun Park(박정훈),Jin su Jeong(정진수),Jae won Lee(이재원),Hyuk Choi( 최혁) 대한전자공학회 2016 대한전자공학회 학술대회 Vol.2016 No.6
Intervertebral disc degeneration (IVD) is one of the important causes of low back pain and is associated with inflammation induced by interaction between macrophages and the human annulus fibrosus (AF) cells. Low level light therapy (LLLT) has been widely known to regulate inflammatory reaction. However, the effect of LLLT on macrophage-mediated inflammation in the AF cells has not been studied till date. The aim of this study is to mimic the inflammatory microenvironment and to investigate the anti-inflammatory effect of LLLT at a range of wavelengths (405, 532 and 650 nm) on the AF treated with macrophage-like THP-1 cells conditioned medium (MCM) containing proinflammatory cytokines and chemokines (interleukin-1beta, tumor necrosis factor-alpha, interleukin-6 and 8). We observed that AF cells exposed to MCM secrete significantly higher concentrations of IL-6, IL-8, IL-1b and TNF-a. LLLT markedly inhibited secretion of IL-6 at 405 nm in a time-dependent manner. Level of IL-8 was significantly decreased at all wavelengths in a time-dependent manner. We showed that MCM can induce the inflammatory microenvironment in AF cells and LLLT selectively suppressed IL-6 and 8 levels. The results indicate that LLLT is a potential method of IVD treatment and provide insights into further investigation of its antiinflammation effect on IVD.
Stabilization of the surface of nitinol stent for cerebral aneurysm prevention
Chang-Min.Yoo(유창민),Hyo-Geun Nam(남효근),Je-Hee Shin(신재희),Min-Ho Hwang(황민호),Seung-Min Baek(백승민),Hyeong-Guk Son(손형국),Jeong-Hun Park(박정훈),Jin-Su Jeong(정진수),Jae-Won Lee(이재원),Hyuk Choi(최혁) 대한전자공학회 2016 대한전자공학회 학술대회 Vol.2016 No.6
Nikel titanium shape memory alloys (NiTi) are promising materials due to their shape memory effect. The disadvantage of the nickel is the toxicity, there are too many restrictions on the use of the human body. Hence, if the proper surface modification is chosen, the surface of NiTi can be tranquilized and smooth. Also, toxic chemicals can be protected by oxide film. The polishing method we have used is electro-polishing which is simple enough, economical and can handle wide range at once. In this study, we are surface modification NiTi by surface electro-polishing. The polishing method we have used is electro-polishing which is simple enough, economical and can handle wide range at once. We have used AFM(atomic force microscopy), SEM(scanning electron microscopy), OM(optical microscope) to analyze the roughness, and formation of surface of NiTi stent. To measure corrosion resistance, steady potentiostat was used to corrosion test. Our study group have concluded that condition of 40V 10seconds of electro-polishing showed the optimal stabilization of the surface.
Baek, Ji-Min,Son, Seung-Woo,Park, Jung Ho,Park, Jong-Keun,Kwak, Jeong-Geun,Yoon, Jacoby,Bang, Dong-Soo,Lee, Jung-Hee,Kim, Taewoo,Kim, Dae-Hyun Elsevier 2018 Solid-state electronics Vol.147 No.-
<P><B>Abstract</B></P> <P>We have fabricated and characterized L<SUB>g</SUB> = 0.5 μm In<SUB>0.52</SUB>Al<SUB>0.48</SUB>As/In<SUB>0.7</SUB>Ga<SUB>0.3</SUB>As pseudomorphic high-electron-mobility-transistors (PHEMTs) on a 3-inch InP substrate. Stepper-based photo-lithography was used in all the process steps for device fabrication, aiming to miniaturize key device geometries, such as gate-to-source and gate-to-drain spacing. The fabricated device with L<SUB>g</SUB> = 0.5 μm exhibits an excellent maximum transconductance (g<SUB>m_max</SUB>) of 1.9 S/mm at V<SUB>DS</SUB> = 1.5 V and an ON-resistance (R<SUB>ON</SUB>) of below 0.4 Ω-mm. A high value of g<SUB>m</SUB> in our device leads to a fantastic combination of current-gain cut-off frequency (f<SUB>T</SUB>) of 120 GHz and maximum oscillation frequency (f<SUB>max</SUB>) of 366 GHz at V<SUB>DS</SUB> = 0.8 V. These remarkable characteristics stem from the compact geometry design of the In<SUB>0.52</SUB>Al<SUB>0.48</SUB>As/In<SUB>0.7</SUB>Ga<SUB>0.3</SUB>As PHEMTs with L<SUB>GS</SUB> = L<SUB>GD</SUB> = 0.4 μm, coupled with an optimized gate recess process that yields tight control of side-recess spacing (L<SUB>side</SUB>). More importantly, the product of f<SUB>T</SUB> and L<SUB>g</SUB> in this work yields 60 GHz-μm which is the highest in any field-effect-transistor (FET) technology on any material system.</P>
The Isolation and Identification of Soybean Pod and Stem Blight in Taiwan
Min-Jung Seo,Chien-Hua Chen,Kil Hyun Kim,Seuk-Ki Lee,Hong-Tae Yun,Yeong-Hoon Lee,Beom-Young Son,,Jung-Tae Kim,Jin-Seok Lee,Hwan-Hee Bae,Chang Hwan Park,Seong-Bum Baek,Jeom-Ho Lee 한국국제농업개발학회 2015 韓國國際農業開發學會誌 Vol.27 No.3
미이라병은 Diaporthe/Phomopsis complex에 의해 유발되는병으로 콩 재배기간 중 따뜻하고 습한 환경에서 종자가 성숙되면 감염률이 높아지며 감염된 콩 종자는 외관상 품질뿐만아니라 종자 활력이 저하된다. 미이라병에 대한 연구를 수행하기 위하여 대만에 위치한 아시아채소개발연구센터(AVRDC)의 콩 시험포장에서 미이라병 병징을 보이는 콩 줄기를 채집하고 이로부터 3개의 곰팡이 균주(isolate)를 분리하였다. 배지위에서의 곰팡이 균사의 생육특성, 현미경하에서 관찰된 알파,베타 분생자(conidia)의 모양 그리고 PCR-RFLP 분석으로, 3개의 균주는 Diaporthe phaseolorum var. sojae 으로 확인되었다. 한편, 미이라병 저항성 육종을 위해서는 유전자원과 계통의 검정이 선행되어야 하는데, 인공접종을 위해서 분생자의최적 배양조건을 탐색하였다. 그 결과 배지는 PDA, 온도는24oC에서 잘 배양되었으며, 일장은 암조건에서는 균사체만 유도되고 분생자는 유도되지 않았으며, 24시간과 15시간의 일장에서는 균사체 유도 및 분생자의 유도 정도에 차이가 없었다.또한 잎-줄기와 꼬투리, 두 개의 접종 부위에 따른 미이라병감염률을 조사하였는데, 두 접종 부위에 따른 미이라병 감염정도는 통계적인 유의차는 나타나지 않았으나 잎-줄기에 접종한 개체 보다 꼬투리에 접종한 개체의 종자 감염률이 높은 경향을 보였다. Phomopsis seed decay (PSD) caused by Diaporthe phaseolorum var. sojae (Lehman) Wehmeyer, Diaporthe phaseolorum (Cooke & Ellis) Sacc. var. caulivora Athow & Caldwell, and Phomopsis longicolla Hobbs reduces quality of soybean (Glycine max (L.) Merr.) seed when it is wet and warm condition during seed maturation period. To study of the PSD in Taiwan in March 2008, three unidentified fungal isolates (isolate1, isolate2 and isolate3) were isolated from soybean stems infected with pod and stem blight which is associated with seed decay. Based on their morphological and genotypic characteristics, three isolates were regarded as Diaporthe phaseolorum var. sojae. For PSD assay, we found that the best condition for the fungal isolates growth was on potato dextrose agar (PDA) media at 24°C temperature for 24 or 15 hr photoperiod. Leaf- stem and pods of soybean were inoculated by an atomizer with two isolates among three isolates to investigate PSD infection. In the result of two inoculation parts with two isolates, there was no significant difference in degree of pod infection and seed infection rate (%) between isolate2 and isolate3, but there was a tendency that pod inoculation than leaf- stem inoculation caused higher level of seed infection. These isolates obtained in this study would be applicable to screening of PSD resistant soybean germplasms in the breeding program.