국내산 중하(Metapenaeus joyneri) 내 주알레르겐 규명 : 가열 및 소화액에 의한 변화

윤성호,김현아,김현미,최정희,서창희,남동호,김윤근,민경업,박해심 대한알레르기학회 2004 천식 및 알레르기 Vol.24 No.2

The HBV DNA Amounts in Serum Have No relationship with ALT level and Hetergeneous Population Coexits in Chronic Hepatitis B Virus Infection

Chun, Yoon-Keun,Ha, Joo-hun,Hong-Jung-Woo,Oh, Soo-Myung,Kim, Sung-Soo 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

Yoon-Keun Chun¹,Joohun Ha□Hong-Jung Woo□, Soo Myung Oh□,Sung Soo Kim□ ¹Department of Molecular Biology, College of Medicine,²Department of Surgery, college of Medicine,³Department of Internal Medicine, College of Oriental Medicine,and ⁴East-Weat Medical Reserch Institute,Kyung Hee University, Seoul, Korea. The HBV DNA Amounts in Serum Have No relationship with ALT level and Hetergeneous Population Coexits in Chronic Hepatitis B Virus Infection. Proceedings of International Symposium on East-West Medicine, Seoul. 212-230, 1999. -Hepatitis B is caused by hepadnavirus. Hepatitis B virus replicates through 3.5kb pregenomic RNA intermediate which is regulated by core promoter. Pathogenesis of hepatitis B virus has been bilieved the result of host immune response. But recently many studies have reported that high level of viral replication caused by mutation in core promoter might result in severs hepatitis. But these studies were performed in vitro, not in vivo. So there is yet debate about which factor, viral of host factor, is more important in pathogenesis of hepatitis B virus. So we measured real viral replication level in 204 chronic hepatitis B patients by quantifying HBV DNA from sera by our novel PCR-based more sensitive method, and compared these results with ALT level measured from same sera, which indicates liver cell damage. Surprisingly there are no significant correlation between HBV DNA quantity and ALT level. Then we cloned core promoter region. In SSCP, we found that many viral mutants coexist in one patient. Base on SSCP result, we chose main viral core promoter type in each patients, which is thought to determine overall viral replication level in this patient. Main type of core promoter region of each 41 patients were directly sequenced. And with these we measured promoter activity by luciferase assay system and compared promoter activity with on another. We found tha there were some differences in promoter activity according to core promoter sequences. And we constructed replication-competent viral constructs with core promoter from 41 patients and Transfected these into HepG2 cell and measured HBV DNA by southern blot. There were also differences in HBV DNA quantity according to core promoter sequences. On these all results we investigated correlation between the effect of HBV core promoter on viral replication in vitro and HBN DNA quantity, ALT level from sera of each patients. We found there is no significant correlation among them. As a result, we concluded that in determining severity chronic hepatitis B patients, host factors of each patient is more important rather than replicative activity of virus itself.

전경대원에서 발생한 결핵의 임상 양상

문창기,박상준,조민구,김영중,김소연,김윤권,정준오,안석진,김은실,서승오,김지훈,최원제,이윤영,박형기,최규영,김현근 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

Background: The purpose of this study was to document the incidence and clinical characteristics of patients with tuberculosis (TB) in combat and auxiliary police, living in a group, in Korea where the incidence rate of active TB in a general population is higher than in Western countries. Materials and Methods:We retrospectively reviewed the medical records of all tuberculosis patients diagnosed at National Police Hospital from January 2002 through December 2004. Results:In 2002-2004, a total of 156 cases of tuberculosis were identified with the mean (Standard deviation) age of 20.6 (±1.0) years. Of these, 134 (85.9%) patients were registered as new cases, 11 (7.1%) as relapse, 2 (1.3%) as failure, 5 (3.1%) as treatment-after-default cases whereas 4 (2.6 %) patients were not included in any categories. Average annual new TB rate and smear-positive TB rate were 86.5/10^(5) and 17.4/10^(5) person-years, respectively. In 12 of 31 smear-positive cases, time from onset of symptoms to diagnosis was more than 30 days. Two multidrug-resistance TB cases were identified and two suspected outbreak episodes of TB had occurred during 3 years. Conclusion:There was no statistically significant difference in the incidence rate of new cases of TB between the general population aged 20 to 29 years and combat and auxiliary police in Korea. 배경 : 국내 결핵의 발생은 감소 추세에 있으나 여전히 후진국형 발생양상을 보이고 있다. 특히 집단생활을 하는 젊은이들에서 발생하는 결핵의 유행이 간헐적으로 알려지고 있어 우려를 낳고 있다. 이에 저자들은 최근 전경대원의 결핵 발병 양상에 대해 알아보고자 본 연구를 시행하였다. 재료 및 방법 : 2002년 1월부터 2004년 12월까지 3년간 경찰병원에서 결핵 진료를 받은 전경대원의 의무기록을 후향적으로 분석하여 연도별 결핵 신환발생률, 도말양성결핵 신환율, 진단 지연, 집단발병, 다제내성결핵을 조사하였다. 결과 : 연도별 결핵 신환자 수(10만명당 발생추정치)는 2002년 50명(83.6명), 2003년 42명(83.7명), 2004년 42명(93.5명)이었고 도말양성 폐결핵 신환자 수는 2002년 10명(16.7명), 2003년 11명(21.9명), 2004년 6명(13.4명)이었다. 3년간 도말양성 폐결핵 환자는 31명이 있었고 그 중 12명은 호흡기 증상 발생 30일이 지나서 진단을 받았다. 다제내성 결핵은 2명이 있었으며 결핵의 집단발병이 의심되는 사례는 2차례 있었다. 결론 : 전경대원과 20-29세 연령군 일반인의 결핵 신환발생률, 도말양성 폐결핵 발생률의 통계적으로 유의한 차이는 없었다.

호산구성 간농양 54예의 임상상

강혜련,권혁수,송우정,이상민,김태범,박혜경,장윤석,김윤근,조상헌,민경업,김유영 대한알레르기학회 2004 천식 및 알레르기 Vol.24 No.2

사회학의 이론적 관점에 따른 레크리에이션 연구

김윤숙,이근모 釜山大學校 附設 體育科學硏究所 1998 體育科學硏究所 論文集 Vol.14 No.-

This study also shows that various recreational problems of modern society can be explained according to the basic principles of sociology such as functionalist point of view, political economics and critical theoretical point of view, symbolic interactions point of view, symbolic and linguistic point of view. To analysis recreation through theoretical aspect of sociology was as follows; 1. The functionalist point of view is that recreation contributes to the harmonious maintenance and operation of the social organization. 2. The political economics and critical theoretical point of view, a Marxist point of view criticise the tendencies of consumption-centered capitalist society. In their political apathy, people neglect the social problems for self satisfaction and family-based recreation. The critical theoretical point of view of the Frankfurt sect raises the question of whether recreation is free or not. 3. The symbolic interactions point of view is that recreation has different meanings according to is interpretation by the different perspectives of people in each era. 4. The symbolic and linguistic point of view is that it defines the ideological base of the recreational activities through analyzing its language and studies the recreational goods and services as a symbolic system.

PECVD에 의해 제조된 Sb-doped SnO₂박막의 광학적성질

김근수,윤석영,김광호 부산대학교 생산기술연구소 2000 生産技術硏究所論文集 Vol.58 No.-

플라즈마를 이용한 화학증착법 (PECVD)으로 Corning glass 1737 기판에 Sb-doped SnO2 박막을 증착하였다. 플라즈마 화학증착시 반응변수에 따른 박막의 결정상, 표면형상 및 광투과도를 XRD, SEM, AFM 과 그리고 UV-VIS-NIR Spectrophotometer를 이용하여 분석하였다. Thermal CVD에 비해 PECVD법은 박막의 증착속도를 향상시켰고, 박막의 표면형상을 보다 균일하게 하였다. 반응온도 450℃, 유입가스비 R=1.12, RF power 30W에서 결정성과 광투과도가 비교적 뛰어난 Sb-doped tin oxide films을 얻을 수 있었다. Sb-doped tin oxide films were deposited on Coming glass 1737 substrate by plasma enhanced chemical vapor deposition (PECVD) technique. The films deposited at different reaction parameters were investigated by using XRD, SEM, AFM, and UV-VIS-NIR Spectrophotometer. Compared to thermal CVD,PECVD effectively enhanced the deposition rate and smoothed the surface of tin oxide films. Sb-doped tin oxide films which have a relatively good crystallinity and photo-transmission were obtained at deposition temperature 450℃, input gas ratio R=1.12, and RF power 30W.

무용학에 있어 무용사회학 정립의 의의와 과제

김세정,이윤자,이근모 釜山大學校 附設 體育科學硏究所 1996 體育科學硏究所 論文集 Vol.12 No.-

Developement of dance acadamy has not be developed much, content, object and territory of dance academy are not clear as well. Under these circumstances, we need much effort of studys, and need to study of dance in whole territory for developement of dance academy. Especially, theoretical stands of sociology of dance is need immediately under the present society. Social roll and function of dance, and dance roll and function of society are already recognized. These points are dealt in folklore. These phenomena are due to that there were not studies about unique dance studies, and not only qualities of studies but also qualities of studies are not much comparing to other academies. Lately, some of these about dance are published, and dance theorists are growing. In this time, We need to arrange dance field and to take a triangular position in the sociology of dance as a stimulant, confrontation. As more, sociology of dance is required to take a triangular position as one field of sociology to corver all the social area, as soon as revising to pursue only a aesthetical value of dance. So, next are Meannings and assignments of the sociology of dance according needs of sociology needs of sociology of dance standing. Meannings of the sociology of dance standing 1) It will make develope Dance acadamy, and stimulate the groping of the systematic domain of dance. 2) It will popularization of dance, because it can make clear the phase of position of dance in the practical side rather than ideal side. 3) It will easily make sociology of dance to take part in similar study, like dance aesthetics, dance philosophy and art theory. 4) General, objective and scientific criticism will be possible in criticicizing dance, because it adds not only aesethetic objection but also social side. 5) Choreographers can be interested in social problems, because sociology of dance is getting important, therefore deep creation can be achieved. 6) The populace's response can be high after PHASE 5), the recognition about dance can meet new aspects. 7) Rather serious and systematic studies can be proceeded, through considering dance in relation to society. 8) It will offer a chance to sociology of dance to take important position in a curriculum of dance academy. 9) It is very helpful to similar studies, because studies of sociology of dance are related to general studies of all field of society. 10) More social scientific experimentation studies will be developed, which is differed from present comprehensive studies. 11) It will present our dance socioty' direction, moving formore, our socioty'direction also. Assignments of the sociology of dance standing 1) The exact sociology of dance standing should be set up after discussing specific and purpose of dance. 2) Reserching content should be chosen after arrangement of dance conception and selection of research object. 3) Research territory has to be discussed by arrangement of research content. 4) Adaptable research method for sociology of dance has to be studied. 5) It should be studied about thoretical background of sociology of dance and boundary and theory application of sociology. 6) The people studing sociology of dance should be multitudinous. 7) The meeting and institude studying sociology of dance are acutely required and lots of qualitive and quantive research are needful.

결합재 페이스트 충전에 따른 포러스콘크리트의 물성에 관한 기초적 연구

윤상혁,양동일,정근호,김성식,이영도,정상진 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1(구조계)

Although porous concrete is recently used as a pavement at a parking lot, a public squre and a bicycle road, we use without enough examining. Most the maintenance of quality for porous concrete is only dealt with strength and color tone. Also, there is not et enough fundamental data about dynamical properties for strength, rate of void and water permeability. Even when it is applied to at the scene, it is been a matter. Accordingly in this study analyzed influences through the dynamical properties, combination, and time to vibration. After the analyzation, they investigated peculiar dynamics which are strength of porous concrete, rate of void, and water permeability follow the rate of increase on an admixture making pozzolan reaction. This is purpose to improve capacity of the sidewalk permeable concrete and development of the economical technique for pavement.

Phenylhydrazine으로 處置한 토끼 赤血球의 Lactate Dehydrogenase Isozymes의 活性度에 關하여

金良均,朴在允,車鍾希,高光三,李根培 조선의대 1983 The Medical Journal of Chosun University Vol.8 No.1

Clancy 방법을 이용한 슬후 십자인대 재건술

김형준,최윤근 全南大醫大 1986 전남의대학술지 Vol.23 No.3