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류광희,지혜미,이화영,강성윤,김경훈,김주희,박경희,박소영,성명순,이영수,양은애,민진영,하은교,이상민,이용원,정은희,최선희,고영일,김선태,남동호,박중원,심정연,안영민,한만용,최정희,신유섭,한두희,대한천식알레르기학회 면역요법/알레르겐연구팀,Gwanghui Ryu,Hye Mi Jee,Hwa Young Lee,Sung-Yoon Kang,Kyunghoon Kim,J 대한천식알레르기학회 2024 Allergy Asthma & Respiratory Disease Vol.12 No.3
Allergen immunotherapy (AIT) has been used for over a century and has been demonstrated to be effective in treating patients with various allergic diseases. AIT allergens can be administered through various routes, including subcutaneous, sublingual, intra-lymphatic, oral, or epicutaneous routes. Sublingual immunotherapy (SLIT) has recently gained clinical interest, and it is considered an alternative treatment for allergic rhinitis (AR) and asthma. This review provides an overview of the current evidence-based studies that address the use of SLIT for treating AR, including (1) mechanisms of action, (2) appropriate patient selection for SLIT, (3) the current available SLIT products in Korea, and (4) updated information on its efficacy and safety. Finally, this guideline aims to provide the clinician with practical considerations for SLIT.
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이화영,강성윤,김경훈,김주희,류광희,민진영,박경희,박소영,성명순,이영수,양은애,지혜미,하은교,신유섭,이상민,정은희,최선희,고영일,김선태,남동호,박중원,심정연,안영민,한두희,한만용,이용원,최정희,대한천식알레르기학회 면역요법/알레르겐연구팀,Hwa Young Lee,Sung-Yoon Kang,Kyunghoon Kim,Ju Hee Kim,Gwanghui Ryu,J 대한천식알레르기학회 2024 Allergy Asthma & Respiratory Disease Vol.12 No.3
Allergen immunotherapy (AIT) is a causative treatment of allergic diseases in which allergen extracts are regularly administered in a gradually escalated doses, leading to immune tolerance and consequent alleviation of allergic diseases. The need for uniform practice guidelines in AIT is continuously growing as the number of potential candidates for AIT increases and new therapeutic approaches are tried. This updated version of the Korean Academy of Asthma Allergy and Clinical Immunology recommendations for AIT, published in 2010, proposes an expert opinion by specialists in allergy, pediatrics, and otorhinolaryngology. This guideline deals with the basic knowledge of AIT, including mechanisms, clinical efficacy, allergen standardization, important allergens in Korea, and special consideration in pediatrics. The article also covers the methodological aspects of AIT, including patient selection, allergen selection, schedule and doses, follow-up care, efficacy measurements, and management of adverse reactions. Although this guideline suggests the optimal dosing schedule, an individualized approach and modifications are recommended considering the situation for each patient and clinic.
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안강모 ( Kangmo Ahn ) 대한천식알레르기학회 2018 Allergy Asthma & Respiratory Disease Vol.6 No.S
Food allergy is an immune-mediated adverse reaction that occurs mainly by consumption of food. Some of the children with food allergies have mild symptoms like urticaria and pruritus, while others manifest fatal symptoms like anaphylaxis. Many cases develop in infants and children, and disappear spontaneously over time. The prevalence of food allergy is known to be up to 6% of children and 3%-4% of adults. Growing concern is that prevalence of food allergy seems to be increasing. The prevalence, common aller gens and natural course of food allergy vary according to the race, age, eating habits, and unknown factors. In Korea, many re searchers have reported regional data on food allergy for comparison with those of foreign countries. Awareness is increasing and food labelling is being established to help people avoid allergenic foods. In the future, monitoring of prevalence and common food allergens at regular intervals is needed to make appropriate policies for children with food allergy. There are still lack of data on pathogenesis, natural course and clinical trials of immunotherapy in Korean children. In addition, it is necessary to form a consensus on primary prevention of food allergy by early exposure to allergenic foods. Further regional studies should be performed to ex pand our understanding of food allergy and to lead to proper management for Korean children with food allergy. (Allergy Asthma Respir Dis 2018;6 Suppl 1:S44-51)
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알레르기 질환 유무에 따른 삶의 질 및 스트레스 비교분석
김철우(Cheol Woo Kim),박중원(Jung Won Park),홍천수(Chein Soo Hong),김용순(Yong Soon Kim),박지원(Jee Won Park),김기연(Gi You Kim),송영신(Young Shin Song) 대한천식알레르기학회 2001 천식 및 알레르기 Vol.21 No.4
Background and objective: In assessing the health-related quality of life of subjects with allergy, it is important to measure outcomes which are relevant to the concerns of patients. The goals of this study were to compare health-related quality of life and stress level among allergy, healthy and other - diseases groups, and also to compare the relationship of health-related quality of life and stress. Method: The study group consisted of 129 subjects with allergy, 139 healthy subjects and 68 subjects with other-diseases. The allergy group was divided into two sub groups: pure allergy group(65) and allergy group with other diseases(64). They completed a questionnaire measuring perceived health-related quality of life, stress and demographic characteristics. The health-related quality of life score was measured by Notingham Health Profile and the stress level was measured by Ok-Suk Lee's instrument. Results: (1) In allergy group with other diseases, the total scores of health-related quality of life were significantly higher than for healthy, pure allergy and other-diseases groups. The results indicated that the perceived health-related quality of life of allergy group with other diseases was in the lowest status among the four groups. (2) Forty-two percent of allergy group with other diseases were in need of treatment for stress level. (3) Level of stress and scores of health-related quality of life have shared linear correlation in healthy and allergy group; higher stress indicates lower status in the quality of life for both groups. Conclusion: This study was examined the QOL and the stress level of allergy subjects. When compared with healthy and other-diseases groups, the scores of QOL and the level of stress of the pure allergy group were higher than those of the healthy group, and those of the allergy group with other diseases were also significantly higher than those of the other-diseases group. These results suggest a necessity for futher assessment to improve the QOL and to reduce the stress in allergy subjects. (J Asthma Allergy Clin Immunol 21: 647-56, 2001)
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