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목련 (Magnolia kobus DC. var. borealis Sarg.) 추출성분의 항균성에 관한 연구
김윤근 한국목재공학회 1999 목재공학 Vol.27 No.1
Antimicrobial activities of the organosoluble extracts, seperated fractions and isolated lignans from the leaves tissue of Magnolia kobus DC. var. borealis Sang. were investigated. The results are summarized as follows : 1. The inhibitory components against the spore growing test were concentrated on light petroleum ether and diethyl ether soluble fractions. The light petroleum ether solubles of the leaves tissue had terpenes compound, so, that they caused growing inhibition. These appearance showed high values of Rf on TLC bioautography and GC analyses with monoterpenes. 2. In the lignans, syringaresinol(XIII), medioresinol(VI), phillygenin(VIII), kobusinol A(X) showed relatively high inhibitory effects in the spore growing test, and these are all showed structural characteristic of the phenolic hydroxyl group of guaiacyl and syringyl skelecton. 3. The light petroleum ether soluble fraction showed the strongest inhibitory effect against the antimicrobial activity in the seperated fractions. 4. The inhibitory effects of the lignans against the bacteria showed not so pronounced independantly, but the extracts and separated fractions contained with these lignans showed something synergism.
목련 (Magnolia kobus DC. var. borealis Sarg.) 의 추출성분 : 각 부위의 리그난 Lignans from the each tissue
김윤근 한국목재공학회 1998 목재공학 Vol.26 No.4
Xylem, bark and flower buds of Magnolia kobus DC. var. borealis Sarg. were extracted with ethanol. Arid then the ethanol extracts were fractionated with diethyl ether. The lignans structure of the dietht ether fractions were determined by spectroscopic methods. The results art summarized as fellows : 1. Three compounds, aschantin(X-I), yangambin(X-II), (-)syringaresinol(X-III), tetahydrofurofuranoid lignans were isolated from the xylem. 2. Five compounds were isolated from the bark. These are all tetahydrofurofuranoid aschantin(B-I), yangarmbin(B-II), medioresinol(B-III), (+)syringaresinol(B-IV), and tetahydrofurofuranoid, kobusinol B(B-V). 3. Three tetahydrofurofuranoid lignans, kobusin(F-I), aschantin(F-II), yangambin(F-III) were isolated from the flower buds. 4. Isolated lignans form the each tissue were two types of tetrahydrofurofuran type and tetrahydrofuran type. 5. The tetrahydrofurofuranoid lignas were five compounds such as kobusin, aschantin, yangambin, medioresinol, and syringaresinol, while the tetrahydrofuranoid lignans was kobusinol Bo. 6. Most of these lignans were substituted with the methylendioxy or methoxyl groups.
기관지천식의 가족적인 발현 및 아토피와 기관지과민성의 유전적인 역할
김윤근,이상록,손지웅,조상헌,이명현,고영률,민경업,김유영 (Yoon Keun Kim,Sang Rok Lee,Jee Woong Son,Sang Heon Cho,Myung Hyun Lee,Young Yoll Koh,Kyung Up Min,You Young Kim) 대한천식알레르기학회 1998 천식 및 알레르기 Vol.18 No.1
Background: Familial aggregation of the phenotypes can be caused by common environmental and genetic factors, but there has been no family study on familial aggregation of the bronchial asthma, and genetic role of atopy and bronchial responsiveness in the development of asthma in Korean families. Objective . We did family study to evaluate the familial aggregation of bronchial asthma, and the genetic role of atopy and bronchial responsiveness in the development of asthma. Materials and Methods '. Questionnaire, serum total IgE level, skin prick test with 10 common aeroallergens, and bronchial responsiveness to methacholine were performed in 154 parents of atopic asthmatics, 72 parents of atopic control, and 65 parents of non-atopic control. Resulta '. Bronchial asthma was more prevalent in parents of atopic asthmatics(7.1% ) than in parents of non-atopic control(0% ). Geometric mean of serum total IgE level was not different among parents of atopic asthmatics, atopic control, and non-atopic control(2.03+0.06, 2.10 +0.07, and 1.89 +0.09 IU/ml). Positive rates of skin prick test to 10 common aeroallergens were more prevalent in parents of atopic asthmatics(43.0% ) and atopic control(43.0% ) than in parents of non-atopic control(27.8%). Prevalence of bronchial hyperresponsiveness to methacholine was more prevalent in parents of atopic asthmatics(17.0% ) than in parents of atopic control(7.2%) and non-atopic control(1.5%), and slope of dose-response curve was more increased in parents of atopic asthmatics(11.0+ 1.5) than in parents of atopic control and non-atopic control(4.8+ 0.7 and 3.0+ 0.5). Conclusion . Bronchial asthma runs in Korean families, and genetic role of atopy and bronchial responsiveness may be important in the development of asthma.
폴리머 시멘트 모르터의 제특성과 타일의 부착강도 개선에 대한 실험적 연구
김윤근,김아영,김진관,이병호 대한건축학회지회연합회 2006 대한건축학회지회연합회 학술발표대회논문집 Vol.2 No.1
Compared with unmodified mortars, the polymer-modifier mortars have superior qualities of flexural strength, adhesion and durability, so its rage of uses and consumed quantity increase. There is a constructional method of using polymer-modified mortar as a preparation to fill out unevenness on the floor of food factory, kitchen, etc. This paper discusses the strengths and adhesion of polymer-modified mortars as surface preparation materials for floor topping with polymer. This paper discusses the strengths and adhesion of polymer-modified mortars as surface preparation materials for floor topping with polymer. The polymer-modified mortars for surface preparation of polymer mortar are prepared with polymer-cement ratios of 0, 5, and 10% and tasted fir strengths, adhesion in tension.