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신태용,염정열,김원,김현미,박해정,장진이,조성룡,채병숙 우석대학교 생명과학연구소 1998 생명과학연구소 논문집 Vol.2 No.-
We investigated the effect of aqueous extract of Ammomum xanthioides(AXAE) on immediate hypersensitivity. AXAE inhibited systemic anaphylaxis induced by compound 48/80 in mice. AXAE inhibited serum histamine levels induced by compound 48/80 in mice. Moreover, AXAE dose-dependently inhibited histamine release in peritoneal mast cells activated by compound 48/80. These results indicate that the AXAE may be benificial in the regulation of immediate type allergic reaction.
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가정과 수업의 협동학습이 학생의 교과에 대한 흥미와 태도에 미치는 영향
양정혜,신상옥 한국 가정과 교육 학회 1998 한국가정과교육학회지 Vol.10 No.1
The purpose of this (1) to develop the teaching plan based on Cooperative Learning approach and (2)to investigate the effect of students' Interest on Subject mater and Teaaching method and Attitudes to others on the area of Foreign food in Home Economics class. Among those various types of Cooperative Learning's this study adopted 'Learning Together' developed by Johnsons. To investigate these purpose, subject matter were analyzed and reconstructed for Cooperative Learning. The tests were developed to evaluate the interest on the Subject matter and teaching methods, an the attitude to thers of the students. 108 femail high school students were divided into two groups with 54 students-traditional learning condition, Cooperative Learning condition-and had a 5 session. The subject of the class was foreign food including Western, Chinese, and Japanes food. Before and after the class, students were tested. The statistical methods used for the study were t-test. The research findings are as fooows : When the students in the Cooperative Learning classes were compared before and after the test, (1) interest on Subject matter were improved considerably(p〈.001) (2)Interest on Teaching methods were improved considerably p〈.05) (3)Attitude to Others were improved considerably (p〈.001) Therefore when the teaching-learning mldel based on Cooperative Learning was used in Home Economics class, their interest on the subject and teaching methods and attitude to others were improved.
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박상호,온영근,김현정,이태훈,길효욱,김현건,박수진,송해정,한대희,방덕원,신원용,이내희,김성구,권영주 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.1
Background : Microvascular angina or syndrom X is heterogenous and encompasses different pathogenetic entities. Several studies suggest that microvascular angina have good prognosis and occurs predominantly in postmenopausal women. Lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, homocystein, CRP and fibrinogen are the independent risk factor of acute coronary syndrome and are the chief underlying cause of atherosclerosis. We investigated clinical characteristics and markers in patients with microvascular angina. Methods : We studies 23 patients diagnosed with microvascular angina and 16 control group with negative treadmill exercise test and no significant coronary angiogram. We investigated clinical characteristics in patients group and evaluated symptom during a follow-up period of 4.2± 2.5 month. Exercise time in treadmill exercise test was compared between patients and control group. We assessed the level of markers, such as lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, homocystein, CRP and ESR in two groups. Results : There is no difference in age between two groups. Patients group had a tendency to increase in female, hypertension, DM, and smoking history, but there was no statistical significance difference. Exercise duration time was significantly decreased in patients with microvascular angina (p<0,05). Serum lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholestrol, Triglyceride, ESR, Fibrinogen and Homocystein value were no significant difference between microvascular angina and control group. Only CRP was significantly high in patients with microvascular angina (p<0.05). Conclusion : There was no statistical significance difference in age, sex, hypertension, DM and smoking history between two groups but patients group had a tendency to increase the prevalence in hypertension, DM and smoking history, female. Also, Symptom improvement and disappearance in follow-up was presented in 11 patients of 19(57.9%). Exercise tolerance was worse in patients group than control group. CRP value was significantly higher in patients group than control group. There was no statistical significance difference in lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, homocystein, ESR and Fibrinogen between two groups.
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1987학년도 부산대학교 신입생의 실태에 관한 조사연구
李成海,辛碩基 釜山大學校 學生生活硏究所 1987 硏究報 Vol.23 No.1
The purpose of this study is firstly to analyze the status and attitudes of freshmen class of 1987 and secondly through this aratlsis to make a plan that helps improve freshmen's adjustment to university life. The main information analyzed in this study was collected by a questionnaire. Informations asked are as follows . (1) backgrounds of each froshman and his/her family, (2) freshmen's attitudes and expectations toward the university and the major field of study, (3) freshmen's attitudes toward the Korean society. (4) some problems facing freshmen and choice of areas of occupational career. The findings and suggestions of this study are summarized as follow: 1. In the same nhanner of other years the economic problems are the most important concern of freshmen. Most of freshmen are hard up for school expense and want to earn their school expense. Therefore, establishment of improved and expanded scholarship and an additional post management is required. 2. Most of freshmen expect a culture, a dilettante life, a building up their character and the formation of wide personal relation. Specially most of freshmen want to professors' humanistic guidance. 3. Most of freshmen want to participate in student circle activity. Therefore the school authorities need to furnish informations that help freshmen's circle selection, and need to produce atmosphere for freshmen's circle activity. 4. Most of freshmen select a field of study without any informations about that subject of study. Also most of freshmeil did not select their major field of study according to their interests or aptitudes, but they chose their field of study by considering possibility of success in admission competition. 5. About 50% of freshmen regard a university as a preparatory stage of occupational career. Therefore it is necessary for freshrrlen to have knowledge of a function of university. 6. Freshmen's attitude toward Korean society was optimistic, but some of them pointed out the corruption of the society and the problems of economy and domestic politics. Also most of freshmen point out that Pusan is somewhat backward in modern culture compared to that of Seoul.
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Comet assay를 이용한 Ferric Sulfate의 유전자 독성에 대한 연구
박혜련,정태성,김신,강호승 大韓小兒齒科學會 2000 大韓小兒齒科學會誌 Vol.27 No.1
치수절단술은 유치의 치수치료 방법 중 사용빈도가 높은 시술 중 하나로 치수절단 술식에 사용되는 약제는 치수나 주위조직에 무해하여야 하며, 감염이나 내흡수 등의 부작용이 없어야 한다. 본 연구는 임상에서 유치의 지혈적 치수절단 술식의 약제로 사용되는 ferric sulfate의 유전자 독성을 평가할 목적으로 human gingival fibroblast에 ferric sulfate를 다양한 농도와 접촉시간을 설정한 후 comet assay를 이용하여 유전자 독성을 평가하여 보았다. 그 결과는 다음과 같다. 1. 농도에 따른 세포의 유전자 손상정도의 변화는 ferric sulfate의 농도에 비례하여 유전자 손상이 증가하는 양상을 나타내었다. 2. 농도에 따른 세포의 유전자 손상정도는 0.1,mM이상의 농도에서 대조군과 유의한 차이를 나타내었다.(p<0.05) 3. 시간경과에 따른 세포의 유전자 독성의 변화는 대조군과 유의한 차이를 보이지 않았다(P>0.05). Although ferric sulfate has been proposed as an alternative to formocresol in pulpotmy treatment in primary teeth, it has been given little concern regarding its cytotoxicity and mutagenicity. In the present study, we assessed the in vitro genotoxic effect of a ferric sulfate on human gingival fibroblast cell line (HGF-1), DNA damage was evaluated using comet assay (single cell alkaline gel electrophoresis) and obtained the results as follows: 1. A dose-response relationship was found between ferric sulfate concentrations (0 to 5mM)and DNA damages. 2. Above the concentration of 0.1mM, DNA damage was significantly increased than those of the control (p<0.05). 3. At the fixed concentration of 0.05mM, no significant difference was found between exposure time and DNA damage. These findings suggest that ferric sulfate as a pulpotomy agent can induce DNA damage in human gingival fibroblasts.
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강신몽,이원태,고영창,최상규,김윤희,이홍석,서재관,윤중진,이혜경,최득린,김종열,윤창육,변명식,이장홍 大韓法醫學會 1991 대한법의학회지 Vol.15 No.2
Individual identification is an important part in medicolegal field especially in mass disaster. At July, 27, 1989, KAL KE-803 was crashed on landing at Tripoli International Airport, Liba. The plane was caught in fire and sixty eight Koreans were sacrified. The majority of victims were severely charred and injured. The authors examed all dead bodies and successfully identified all the cases through visual, anthropological, odontological, radiological and pathological methods including fingerprint and blood typing.
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점증적 최대운동이 항산화 효소의 혈중 농도에 미치는 영향
강신범,이상우,김상권,서해근,김준모 東亞大學校附設스포츠科學硏究所 1999 스포츠科學硏究論文集 Vol.17 No.-
The purpose of this study is to examine how exercise stimulus effects on the boold concentration of antioxidant enzymes. And then, the results of analysing the boold concentration of antioxidant enzymes before and after graded maximal exercise based on high school's 7 males, are as follows: 1. The blood concentration of SOD is found to have a significant increase before and after graded maximal exercise. 2. The blood concentration of CAT is found to have a significant increase before and after graded maximal exercise. 3. The blood concentration of CAT is found to have a significant change. As the above results, the severe exercise of short time is found to increase the blood concentration of SOD as well as CAT. And then, the blood concentration of GPX is found not to have a significant exchange. To examine the mechanism of the above results manifestly, it is considered that the deep study based on exercise style, duration time and exercise intensity, should be continued.
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