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      • KCI등재

        Clothing Pressure of selected Support Panty Stockings

        (Jeong Eun Park),(Su Kwang Sung),(Min Kyu Song) 한국의류산업학회 2000 한국의류산업학회지 Vol.2 No.5

        The purpose of the study was to obtain the basic data on the self-adjusting ability of the support panty stockings. Ten healthy women in the twenties were selected as subjects and clothing pressure of 9 support panty stockings made of single covered yarn (SCY) and double covered yarn (DCY) were measured under the standard environmental condition for the study. Data was analysed statistically according to body postures, sides, and parks. The results were as follows: Clothing pressure according to body posture was order of `sitting-on-a-chair`, `stepping-up-a-stair`, and `standing`. High clothing pressure was obtained in the parts of calf (9.4 gf/㎠) in `standing` and knee (9.7 and 16.5 gf/㎠) in both `stepping-up-a-stair` and `sitting-on-a-chair`, respectively. The order of clothing pressure with body sides was `front`, `side`, and `back`. The highest clothing pressure was knee (18.8 gf/㎠) on the front, thigh (8.8 gf/㎠) on the side, and calf (6.4 gf/㎠) on the back. Clothing pressure of DCY at abdomen and knee was a little higher than those of SCY 3. In terms of material structure variation, clothing pressure of thigh, calf and ankle with SCY was a little higher than those with DCY, while clothing pressure of abdomen and knee with DCY was a little higher than those with SCY.

      • 위발성 위장관 악성림프종 환자에서 항암치료의 효과

        김찬규,신영록,김현정,배상병,이남수,이규택,박성규,원종호,홍대식,박희숙 순천향대학교 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1

        Purpose: The gastrointestinal (GI) tract is the most common site of extranodal non-Hodgkin's lymphoma (NHL), which is increasing in incidence, but there is no established optimal treatment modality. Thus, this study was investigated the clinicohistologic feature, the therapeutic modalities, and the prognosis for GI-NHL, as well as the factors affecting it. Methods: We retrospectively analyzed 45 patients who had been diagnosed as having GI-NHL and had been followed up from July 1994 to February 2005 at Soonchunhyang University Hospital. The patients were divided into groups according to the site of origin and to various other features, and the survivals of the various groups were compared. The modified Ann Arbor system and WHO classification were adopted for staging and histopathologic classification, respectively. Results: GI-NHL of the stomach, small bowel, ileocecal region, and colon occurred in 28 patients (62.2%), 5 patients (11.1%), 3 patients (6.7%), and 8 patients (17.8%), respectively, In one patient, the entire gastrointestinal tract was diffusely involved. The median age of patients was b5 years (25~78 years), and male-to-female ratio was 1:1.1. Fourteen patients were in stage Ⅰ, 24 in stage Ⅱ, 4 in stage Ⅲ, and 3 in stage Ⅳ. Surgical resection was performed in 19 patients, and combination chemotherapy was performed in 43 patients. Surgical resection only was performed in 4 patients, Chemotherapy only was performed in 26 patients. The expected overall 5 year survival of 45 patients was 39.6%, and there was a significant survival difference between the stages, but between sites of origin (p=0.842). The most important factors influencing the survival was the stage and other factors were not significant. Conclusion: The stomach was the most common site of GI-NHL. Most GI-NHL were localized Stage was the most important prognostic factor. However, Prospective randomized studies are needed to approve the therapeutic modality.

      • KCI등재

        고관절 반 치환술의 대퇴 골절 예방을 위한 강선 고정의 효과

        유정한 ( Jeong Han Yoo ),박용욱 ( Yong Wook Park ),박진수 ( Jin Soo Park ),노규철 ( Kyu Cheol Rowe ),정국진 ( Kuk Jin Chung ),김홍균 ( Hong Kyun Kim ),김형년 ( Hyong Nyun Kim ),임희준 ( Hee Joon Lim ),이철 ( Cheol Lee ),황지효 ( 대한고관절학회 2009 Hip and Pelvis Vol.21 No.2

        목적: 무시멘트형 양극성 반 인공 관절 치환술에 있어서 수술 도중 발생하는 대퇴 골절 예방을 위한 예방적 강선 고정술의 효과를 분석하고자 한다. 대상 및 방법: 2004년 1월부터 2008년 8월까지 무시멘트형 양극 인공 관절 치환술을 받은 65세 이상의 환자 48명(1군)을 대상으로 하여 강선을 사용하지 않은 48명의 환자(2군)와 비교하였다. 평균 나이는 75.4세(1), 73.6세(2)이었고 평균 추시 기간은 19.1개월(1), 18.3개월(2)이었다. 수술 도중 골절 발생율 외에 수술 시간, 수술 도중 예상 출혈량, 입원 기간, 방사선학적 안정성을 측정하였고 임상적 평가를 위한 대퇴 통증과 Jensen의 기능 점수와 Parker와 Palmer의 활동 점수를 비교하였다. 결과: 1군에서는 수술 도중 골절이 발생하지 않았으며 2군에서 4예(8.3%)가 발생하였다(p=0.041). 수술 시간은 각각 172분(1), 162분(2) 예상 출혈량은 866 cc(1), 855 cc(2), 입원기간 36일(1), 35일(2)이었다. 방사선학적으로 침강은 1.59 mm(1), 1.67 mm(2)이었으며 임상적으로 대퇴 통증이 1예(1), 2예(2) 관찰되었다. 임상적으로 Jensen의 기능 점수는 평균 2점(1) 2.2점(2), Parke와 Palmer의 활동 점수는 평균 5.2점(1), 5.3점 (2)이었다. 결론: 무시멘트형 인공 관절 치환술에 있어서 예방적 강선 고정술은 골절률을 의의있게 감소시켰다. Purpose: The purpose of this study was to assess the effect of a prophylactic cable fixation for prevention of femoral fractures in cementless bipolar hemiarthoplasties. Materials and Methods: Forty-eight cementless bipolar hemiarthroplasties with prophylactic cable fixations on the femur were performed in patients>65 years of age between January 2004 and August 2008 (group 1). The control group which did not undergo prophylactic cable fixation included 48 cases (group 2). The mean age was 75.4 years (group 1) and 73.6 years (group 2). The patients were followed up for an average of 19.1 (group 1) and 18.3 months (group 2). The intra-operative fracture rates were compared. Additionally, operative time, estimated blood loss (EBL), and length of hospital stay were compared. Radiologic assessment for stem stability was performed. Clinical assessment was evaluated by the thigh pain and Jensen`s functional score, and Parker & Palmer`s mobility score. Results: There was no fractures in the cabled group (1), and 4 fractures (8.3%) in the control group (2; p=0.041). The mean operative time was 172 minutes (1) and 162 minutes (2), the EBL was 866 cc (1) and 855 cc (2), and the duration of admission was 36 (1) and 35 days (2), respectively. Radiologically, subsidence was 1.59 mm (1) and 1.67 mm (2). Clinically, one (1) and two (2) thigh pains were recorded and the functional score of Jensen was 2 (1) and 2.2 points (2), and the mobility score of Parker and Palmer was 5.2 (1) and 5.3 points (2), respectively. Conclusion: Prophylactic cable fixation is effective for reducing intra-operative femoral fractures.

      • 폐결핵 환자 혈청에서 수용성 Interleukin 2 수용체 및 Adenosine Deaminase 활성도에 관한 연구

        고정희,박성규,백상현,박찬권,박병수,안진영,최우석,박정규 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.1

        Interleukin-2 (IL-2) induces T cell proliferation in an autocrine manner and provides a means by which antigen triggered T cells can be clonally expanded in vitro. During the following activation, the activity of IL-2 is mediated by specific high affinity IL-2 binding membrane receptors which are expressed shortly after activation. In this process, a 42 KD-fragment (soluble IL-2R) is continuously cleaved off and circulates as a soluble marker of T lymphocyte activation. Elevated level of soluble IL-2R has been identified in the serum of patients with malignant autoimmune and allergic disorders, systemic parasitic infection, undergoing graft versus host disease, acute or chronic lymphocytic leukemia and HIV-infection. ADA (adenosine deaminase) completes the process of differentiation of T cell and is essential for progression of T cell maturation. Therefore level of ADA is to correlated with magnitude of T cell immune response. The fact that expression of sIL-2R and ADA activity increases in peripheral blood T-lymphocytes of patients with active pulmonary tuberculosis suggests that T cell activation might have a major role in the pathogenesis of pulmonary tuberculosis. In order to evaluate the T cell immune response in pulmonary tuberculosis, we measured the serum concentration of sIL-2R and ADA activity in 17 patients with current pulmonary tuberculosis, 10 chronic inactive pulmonary tuberculosis, 10 as normal controls. (1) Current pulmonary tuberculosis had significantly higher levels of sIL-2R (237.24±95.47)when compared with those of inactive tuberculosis (78.6±11.06). and the control (68.17±15.4) group. (2) ADA activity in current pulmonary tuberculosis was significantly increased (34.41±20.63) when compared with those of inactive tuberculosis (24.7±14.36) and control (17.65± 5.94) group. (3) There was good correlation between sIL-2R concentration and ADA activity in serum in current pulmonary tuberculosis group. (4) sIL-2R concentration and ADA activity was decreased significantly 6 months after anti-tuberculosis drug medication. In conclusion, sIL-2R concentration and ADA activity in serum in current pulmonary tuberculosis group was increased when compared with those of inactive pulmonary tuberculosis and the control group. By the way, T cell mediated immune response was enhanced in current pulmonary tuberculosis, but in inactive chronic pulmonary tuberculosis who had treated by antituberculosis drug medication, the concentration of sIL-2R and ADA activity was nearly normal.

      • 뇌하수체 종양 제거술 시행 후 뒤늦게 발생한 횡문근 융해증과 동반된 중추성 열

        장제혁,최규남,김일환,노은지,김윤정,유충헌,고정해,박봉수,김태균,권민정,이순희,박정현 인제대학교 2008 仁濟醫學 Vol.29 No.-

        Body temperature is controlled by thermoregulatory center of the hypothalamus. We report a case of 24 years old man with central fever. He was subjected to a partial excision of pituitary tumor compressing optic chiasm four years ago. He has received hormonal therapy for panhypothyroidism after removal of pituitary tumor. And He received gamma knife operation for partially contrast-enhancing masses in suprasellar and both hypothalamic areas that is probably postoperatively remnant or recurrent tumor of pituitary adenoma. One year after gamma knife operation, he presented with a febrile syndrome of unknown origin including rhabdomyolysis. All usual investigations proved negative. We diagnosed him as central fever with rhabdomyolysis. He received medical ICU care with cooling bed, ice pack. And his symptom improved. Postoperative hyperthermia may result following resection of the pituitary tumor. When central fever is suspected taking note of past history, a quick recognition of course of fever can help reduce the using of unnecessary antibiotics and hospital stay.

      • 大食細胞와 T 淋巴球의 抗原特異 結合에 依한 結核免疫

        朴鼎圭,白太鉉,崔大卿 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.1

        In tuberculous immunity, BCG immune macrophages and lymphocytes were tested for antigen specific binding between T lymphocytes and macrophages from peritoneal cavity of C57BL/6 mice. The results were summarized as follows: 1. The number of lymphocytes bound per 100 macrophages reached maximal levels at 3 weeks in BCG immune mice after sensitization with PPD 1 ug/ml(54.2±2.0, p<0.001). 2. Antigen specific binding between T lymphocytes and macrophages were observed in BCG immune mice. 3. In RPMI 1640 cultures, the specific bindings began to decrease after 24 hours and then rapidly decreased over 48 hours. 4. Lymphocytes dissociated from macrophage-lymphocyte clusters were viable above 95% by trypan blue exclusion. 5. Lymphocytes attached to macrophages showed T-pattern of acid α-naphthyl acetate esterase activity. From above results, tuberculous immunity has been associated with antigen specific binding of macrophage and lymphocyte. This experimental models offer the potential for the isolation of T-cells involved in specific cell mediated immune response in tuberculous immunity.

      • 결핵균 30 kDa항원과 Interleukin-2 혹은 Anti-CD28의 병합이 건강인 말초혈액 림프구와 단핵구 증식에 미치는 영향

        박정규,윤상호,조은경,김화중,백태현 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.2

        Cell-mediated immunity is necessary for protection against Mycobacterium tuberculosis. T lymphocytes are thought to play a central role in cell-mediated immune response. And in vitro stimulation of leukocytes with mycobactria or their products induces synthesis and release of several cytokines, including IL-2. To study the T lymphocyte proliferative response to purified 30 kDa antigen from Mycobacterium tuberculosis H37Rv, IL-2 or their combination, peripheral blood lymphocytes and mononuclear cells isolated from healthy subjects were stimulated with the 30 kDa antigen, IL-2 or both. The proliferations of lymphocytes and molnonuclear cells to 30 kDa or 30/32 kDa antigen were significantly increased in PPD(+) group when compared to those in PPD(-) group. It is confirmed here that have shown synergy between 30 kDa antigen and IL-2(250U) in the induction of lymphocytes and mononuclear cells proliferation in PPD(+) group. The proliferative response reflects synergy between two separate activation stimuli. And macrophage-like cells existed in peripheral blood mononuclear cells were shown to help the synergy of the proliferative response to mycobacterial antigen and IL-2. The proliferative responses of lymphocytes and mononuclear cells to 30 kDa antigen were more increased than those to 30/32 kDa antigen. So it was suggested that 30 kDa antigen was the more immunogenic antigen than 30/32 kDa antigen.

      • 혈당측정기 GlucoDr™ System의 평가

        박철영,류미숙,우정택,김성운,김진우,김영설,안규정 대한당뇨병학회 2002 임상당뇨병 Vol.3 No.2

        연구배경: 당뇨병 환자에서 엄격한 혈당조절은 환자의 예후와 밀접한 관련이 있다. 혈당조절을 철저히 하기 위해서는 자가 혈당 측정기의 사용이 필수적이라 할 수 있다. 또한 저혈당이 빈번하게 발생하거나, 위험요소가 있는 환자들에게도 유용하게 사용될 수 있다. 이에 저자들은 전기화학감지법의 원리를 이용하여 국내에서 처음 생산된 자가혈당측정기인 GlucoDr™ blood Glucose Testing System(ALL Medicus, Co, Korea)를 현재 국내에서 시판되고 있는 다른 제품과 비교, 평가하여 임상적 유용성을 살펴보고자 하였다 방법: 혈당측정기준장비는 YSI 2300 STAT Plus(YSI Incorporated, USA)를 사용하였으며 GlucoDr™외에 Glucocard(KDK, Japan), Precision QID(Abbott Laboratories, Co, USA), Glucotrend(Roche, USA), Surestep(Lifescan, USA)의 다른 혈당측정기를 같이 평가하였다. 정밀도, 직선성, 비교방법과의 상관관계 평가, 검체량에 따른 영향, 헤마토크리트에 따른 영향, 검사자에 따른 영향, 항응고제에 따른 영향들을 평가하였다. 결과: 본 연구에서의 주된 평가대상인 GlucoDr™의 평가결과, 정밀도를 나타내는 검사 내, 검사 간 변이계수는 8%이내였으며, 45~500mg/dL 범위에서 R²=0.9906, 0.9984 정도의 직선성을 나타내었다. 본 연구에 있어 비교방법으로 이용한 YSI 2300 STAT Plus와의 상관관계 및 정확도는 y = 1.0058x + 0.453, R = 0.9853인 것으로 나타났다. 검체량이나 검사자 및 항응고제에 따른 측정값에는 유의할만한 차이가 없는 것으로 나타났으나, 헤마토크리트가 증가 또는 감소함에 따라 최소 10%에서 최대 26% 가량의 영향을 받는 것으로 관찰되었다. 결론: GlucoDrTM는 국내 사용되는 다른 혈당측정기와 비교하여 유용할 것으로 생각된다. Background: Self-monitoing blood glucose devices are sidely used in monitoring and point-of-care testing for the management of diabetic patients. We performed the present study to evaluate the performance of the GlucoDr™ blood glucose testing system using an electrochemical technique. Method: The GlucoDr™ was evaluated for linearity, precision, comparison of method, the effect of sample volume, hematocrit concentration, reapplication, operator and application methods. Results: The GlucoDr™ showed good linearity for glucose concentrations ranging from 52mg/dl to 475mg/dl(r²=0.971). The single day, and day-to-day, CV were within 8%. Excellent correlation was found between the GlucoDr™ and YSI 2300 STAT Plus(y=1.0058x + 0.453, r²=0.9710). The sample volume, reapplication, operator and application method produced no significant effect on the test result. An overestimation in the glucose values was found with low hematocrit concentrations. There was no significant effect by the anticoagulants, with the exception of citrate. Conclusion: The GlucoDr™ showed good linearity, precision and correlation with the reference method and provided rapid and reliable result for blood glucose levels. Therefore, the GlucoDr™ seems appropriate for clinical use in the management of diabetic patients.

      • 저온 및 상온 저장한 백미의 품질 특성

        박석규,박정로,박미연 순천대학교 기초과학연구소 1994 基礎科學硏究誌 Vol.5 No.-

        The Quality characteristics of milled rice stored at 5℃ and room temperature for 6 months were investigated. Major fatty acids of milled rice were linoleic > oleic > palmitic acid. The rice stored at room temperature had slightly lower content of unsaturated fatty acids than that that stored at 5℃. The major volatile compound of the rice was hexanal, and storage temperature did not effect the content of hexanal. The content of volatile compounds of cooked rice differed greatly from uncooked rice ; in boiled rice, hexanal tended to decrease and several unidentified compounds (UN 3, 5, 7) to increase. The starch powder of milled rice stored at room temperature had higher water binding capacity, but had slightly lower iodine value, amylose content, transmittance at 625㎚, swelling power and solubility than that stored at 5℃.

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