이온교환법에 의한 탈질소 공정개발의 기초연구 (Ⅲ) : 희분식 반응기에서의 반응속도론 A kinetic study in the batch reactor

채용곤,이동환,김승일,윤태경,홍성수,이민규 한국환경과학회 2000 한국환경과학회지 Vol.9 No.2

A kinetic study for anion exchange was performed for commercially available Cl^- type anion exchange resin in use to remove nitrate in water. The obtained results from the batch reactor were applied to the Langmuir and Freundlich models. The constants for Langmuir model were q_max=29.82 and b=0.202, and for Freundlich model were K=5.509 and n=1.772. Langmuir model showed better fit than Frendlich model for the experimental results. Ion exchange reaction rate was also calculated and the approximate first-order reaction, rate constant k_1 was 0.16 L/㎎·hr. Effective diffusion coefficient was obtained in the range from 9.67×10 exp (-8) to 1.67×10 exp (-6) ㎠/sec for initial concentration change, and from 6.09×10 exp (-7) to 3.98×10 exp (-6) ㎠/sec for reaction temperature change. Activation energy during the diffusion was calculated as 36 ㎉/㏖.

소세포종양에 관한 면역조직화학적 및 전자현미경적 연구

서재홍,임성철,김용임,양정열 대한병리학회 1997 Journal of Pathology and Translational Medicine Vol.31 No.11

信號交叉路의 交通特性과 左回轉 禁止에 따른 運營效果에 관한 硏究

홍익상,공창환,정우영,임채문 대구대학교 산업기술연구소 1993 産業技術硏究 Vol.12 No.-

This study analyzed the characteristics of the operation of left turns at intersections of the streets in Taegu City. The points of the study were as follows: increase of traffic capacity, decrease of delay time, and to do so this study aims at seeking a way for the most appropriate signal cycle and an effective way to operate intersections. The following are the results: 1st The arterials of Taegu City have a high rate of left turns, and yet are not divided into specific functions, which impairs the efficient use of the functions. It is required that a study be made on the way of utilizing the left turn to the maximum of the operational functions of signalized intersections. 2nd As traffic volume and left turn ratio increase, it was revealed that the optimum signal cycle and delay increased, adoption of efficient lanes was analysed to be most effective at the intersection which have a great of traffic volume and a high or rate of left turns. 3rd On the independent intersection in Taegu city, when left turn is prohibited, it may give poor approaches, but according to analyses this will bring a phenomenal decrease in the optimum signal cycle and delay.

成人 男子의 身體構成에 關한 硏究(Ⅰ)

蔡鴻遠,洪相完 慶北大學校 師範大學 體育學硏究會 1987 體育學會誌 Vol.15 No.-

The subjects were 6 male active adultmen(the range of their age was 30∼47 years old), and they were freshmen members in Graduate School of Dong-A University doctorate course majoring in physical education. Body compositions were calculated by body density obtained from skinfold thickness method and underwater weighing. The purpose of this study was to fine out statistical difference between two methods with T-test, and compare correlations among those variables. The conclusions were as followings; 1. Physical Characteristics. Body height and body weight were rather higher and heavier than the common same age group's. 2. T-test between body compositions obtained from skinfold thickness method and underwater weighing method. There were not significant differences between the values of body compositions calculated from two methods(|T|<2.57, p<0.05). 3. Body Compositions. ① % far was 12.50±1.24% (skinfold thickness method) and 17.53±3.26% (underwater weighing method). ② Supposing that two subjects' body weight were same, We could find that the lighter underwater body weight the smaller body density. ③ We could assume that the values of body composition obtained from underwater weighing method were more accurate than those from skinfold thickness method. 4. Correlations. ① There were very high positive correlations between height and fat(p<0.05), Fat/Height(p<0.05), LBM/Height(p<0.01), and LBM(p<0.001). There were very high positive correlations between body weight and % fat(p<0.05), Fat/Height (p<0.01), and Fat·LBM·LBM/Height(respectively p<0.001). Besides, there were positive and negative correlations between the other values, but not statistical significances. ② There were high correlations between triceps and % Fat, % LBM. ③ There were positive correlations between body density and % Fat, but not a statistical significance. ④ There were positive correlations between vital capacity and residual lung volume % Fat, Fat, LBM, Fat/Height, and LBM/Height respectively, but not statistical significances. ⑤ Between triceps(X) and % fat(Y'), We could calculate regression equation (Y')=0.561X+8.249(Sy.x=1.039, r=0.819, p<0.05), between triceps(X) and Fat/Height(Y'), Y'=0.467X+1.628(Sy.x=1.033, r=0.821, p<0.05), between triceps(X) and % LBM(Y'), Y'=-0.561X+91.755(Sy.x=1.038, r=-0.819, p<0.05), but, in other cases there were not statistical significances because either correlation was low or Sy.x was large.

고출력 펄스 레이저로 증착된 유기필름

홍진수,채희백,안성기,박해윤 순천향대학교 기초과학연구소 2001 순천향자연과학연구 논문집 Vol.7 No.2

유기발광 응용에 성공적으로 사용되어 새로운 물질을 개발할 때 기준으로 사용되는 Alq_3와 TPD필름을 기존의 증착법(열증착법과 스핀코터 기술)을 대체할 수 있는 고출력펄스레이저로 합성하였다. 펠릿 타겟은Q-스위칭 Nd:YAG 레이저의 532 nm와 355 nm를 사용하여 2&10^-6 Torr압력 하에서 용발시킨다. 슬라이드 유리 위에 증착된 필름은 유기발광 디바이스에 사용될 가능성이 있는지 알기 위해 다음과 같은 조사를 하였다: PL,AFM, 흡수 스펙트라, XRD. 355 nm 레이저로 유기필름을 증착하면 532 nm 경우의 필름보다 결합이 적고, 특히 열증착 필름보다 스트레스를 덜 받는다는 사실을 알 수 있다. 또한 타겟의 구조가 Alq_3 다를지라도 레이저 증착법으로 합성된 Alq_3 필름은 열증착과 동일한 구조를 갖는다는 사실을 알 수 있다. 어느 레이저를 사용하건 증착된 필름은 결정구조를 확인할 수 없을 정도로 비정질을 이룬다는 사실을 알 수 있다.

대형물의 RP 작업을 위한 절단 알고리즘의 개발

채희창,강희용,유상훈,이승현,문홍렬 한국공작기계학회 2002 한국생산제조학회지 Vol.11 No.2

Nowadays, as the development period of new products becomes shorter and consumer's requirement is more various, the importance of Rapid Prototyping Technology has been rapidly increased. Rapid Prototyping makes prototypes or functional parts directly using the 3D CAD data. But RP machines can make protypes in limit size. For making large size prototype, we slice solid, which is made of STL file, and then glue sliced solid. And if contact area of part is small, union solid will be easily destroyed for going down of adhesion. So we need to expand contact area, I suggest making a section into stair shape. This paper is concerned with slicing solid on STL file and improving on adhesion.

배추 시스테인 단백질 분해 효소 억제 유전자 BCPI-1의 발현과 종자 발아 및 유묘 생장과의 연관성

홍준기,이은영,김정률,양경애,최영주,정우식,김호일,윤대진,이상열,조무제,임체오 Plant molecular biology and biotechnology research 2003 Plant molecular biology and biotechnology research Vol.2003 No.-

Phytocystatins are protein inhibitors of cysteine proteinases of the papain family that have been identified in both monocot and dicot plants. A cDNA encoding a phytocystatin, BCPI-1 (Brassica Cysteine Proteinase Inhibitor-1) has been isolated from Chinese cabbage (Brassica campestris L. ssp. pekinensis) flower buds. Here, we tested whether BCPI-1 transcription is regulated by hormones, and could be involved in regulating cysteine proteinases during and after germination. BCPI-1 was sensitive to exogenous GA_(3) and ABA, which are important factors controlling seed germination, suggesting that the expression of BCPI-1 is hormonally regulated. We introduced a recombinant plasmid containing the full-length BCPI-1 cDNA under the control of cauliflower mosaic virus 35S promoter into rice embryogenic calli using the particle delivery method, and regenerated a number of transgenic rice plants. Constitutively over-expressed BCPI-1 caused changes in overall plant growth and development, including reduced germination and seedling growth. These data support the role of the BCPI-1 in the regulation of endogenous proteinases during both seed germination and subsequent seedling development. Phylocystatins은 papain계열의 cysteine 단백질 분해 효소 활성을 특이적으로 억제하는 억제자로 다양한 식물 종으로부터 분리되었다. 본고에서는, 배추 화아 cDNA library로부터 분리된 phytocystatin인 BCPI-1(Brassica Cysteine Proteinase Inhibitor-1)의 생체 내 기능에 대해 연구하였다. 먼저, BCPI-1 전사체는 발아 조절에 중요한 영향을 미치는 GA₃와 ABA에 의해 예민하게 증가, 혹은 감소되는 반응을 보임으로써, BCPI-1이 식물 호르몬의 영향을 받으며, 특히 발아나 유묘의 생장 조절에 관련이 있음을 알 수 있었다. Particle bombardment 방법을 통하여 BCPI-1을 벼의 배 형성 세포 내에 도입, 재분화 시켜 형질 전환 벼를 생성하였다. CaMV 35S promoter의 조절에 의해 지속적인 BCPI-1 발현을 보이는 형질 전환 벼의 경우, 발아와 유묘 생장이 현저히 지연되었다. 위의 결과들을 바탕으로, BCPI-1이 식물체 내에서 생성되는 cysteine 계열의 단밸질 분해 효소 활성을 조절하여 종자의 발아와 유묘의 생장에 영향을 미치는 것으로 추측한다.

장중첩증을 동반한 맹장 지방종 1예

홍의실,나병규,김민옥,유일영,채지영,채희복,윤세진,이상전,송형근,박길선,정현용 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.2

대장 지방종은 주로 우측 결장에 호발하고 특히 회맹판 부위와 맹장 부위에 호발한다. 또한 50~60대에 빈도가 높고 증상이 있는 환자에서 장중첩증이 높게는 40~50%에서 보고되고 있어 성인 장중첩증의 원인으로 중요한 비중을 차지한다. 특히 성인 장중첩증 및 장폐쇄의 중요 원인인 악성 종양과 임상 양상이 유사하여 감별진단이 중요하다. 저자들은 반복적인 복통을 주소로 내원한 환자에서 맹장의 4×5㎝의 점막하 지방종이 말단 회장부위와 반복적인 장중첩중이 발생했던 1례를 부분 절제술로 치료하여 양호한 임상 경과를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Lipomas are one of the most common benign nonepithelial tumors of the colon which are often detected incidentally by radiologic investigation or on operation. These tumors are usually without specific symptoms. Colonic lipomas occur most often in the right colon, particularly in the ileocecal valve and the cecum. Most patients are asymptomatic. but tumors larger than 2 cm tend to produce a change in bowel habit. abdominal pain. rectorrhagia and complications including luminal obstruction or intestinal intussusception. Diagnosis can be made by colonoscopy abdominal CT. MRI, or barium enema. We report a case of lipoma of the cecum that originated in the submucosa and presented as a intussusception in a 50-year-old woman with a brief review of the literature.

갑상샘 유두상 암종에서 CD56과 p63 단백 발현

이상호,류려선,서재홍 朝鮮大學校 附設 醫學硏究所 2009 The Medical Journal of Chosun University Vol.34 No.1

Papillary carcinoma of the thyroid (PTC) is the commonest thyroid cancer. Diagnosis of papillary thyroid carcinoma, in many but not all cases, is an easily achievable diagnosis with almost minimal interobservable variability between pathologists. However since the introduction of follicular variant of PTC and the wide threshold range in interpretation of the clearly set pathological criteria for diagnosis of PTC, between pathologists including experts, the diagnosis in some cases became quite difficult. Unfortunately some cases are unjustifiably over-called as follicular variant of PTC as result of the wide inter observable variability between pathologists. CD56 is a neural cell adhesion molecule, hence its expression may affect the migratory capacity of tumor cells. The tumor suppressor protein p53 has recently been shown to belong to a family that includes two structurally related proteins, p63 and p73. Expression of p63, a transcription factor that is transcribed into six isoforms, is important for the regulation of normal development. In this study, we assessed the protein expression and loss using antibodies against CD56 and p63 in normal follicular thyroid neoplasms in an attempt to evaluate its diagnostic value. A total 109 cases were studied with tissues from 49 carcinoma (33 classic papillary carcinoma, 16 follicular variants of papillary carcinoma), 15 follicular adenoma, 17 nodular hyperplasia, 17 lymphocytic thyroiditis and 11 normal thyroid evaluated by immunohistochemistry for the expression of this marker. Our results showed CD56 positive in all the lesions and adenomas except for PTC. CD56 was negative in all PTC cases. p63 showed selective focal positivity in PTC cases, in contrast to other non PTC lesions/tumors. p63 expression was in 25 out of 33 cases of PTC and was consistently absent in all the non PTC cases. Our aim was to study the applicability of difference in CD56, p63 expression as a marker that distin-guishes PTC, including the follicular variant from other We concluded that a panel consisted of CD56 and p63 is of value in distinction of PTC from other thyroid follicular lesion. p63 is a specific but less sensitive marker for PTC than CD56. CD56 is more specific and sensitive marker than p63, however it is a negative rather then a positive marker for PTC.

cDNA array 방법을 이용한 망간에 노출된 흰쥐 뇌기저핵의 유전자발현 분석

이채관,노성민,문덕환,,김정호,손병철,김대환,이창희,김휘동,김정원,김종은,안진홍,이채언 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Objectives: This study investigated the gene expression profile in basal ganglia of manganese-exposed rats based on cDNA array analysis. Methods: For cDNA array, 25 male Sprague-Dawley rats (250±25 g) were intraperitoneally injected with 25 ㎎/㎏ B. W./day of MnCl2 (0.3 ㎖) for 10 days. For dose-related gene expression analysis, rats were intraperitoneally injected with 0.2, 1.0, and 5.0 ㎎/㎏ B. W/day of MnCl2 for 10 days. Control rats were injected with an equal volume of saline. RNA samples were extracted from brain tissue and reverse-transcribed in the presence of [α^(32)P]-dATP. Membrane sets of the Atlas Rat 1.2 array Ⅱ and Toxicology array 1.2 kit (Clontech, Palo Alto, CA) were hybridized with cDNA probe sets. Northern blot hybridization method was employed to assess the dose-related gene expression. Results: Fifty-two genes showed significant changes in expression of more than two-fold. Twenty-eight were up-regulated and 24 were down-regulated in the manganese-exposed group compared to the control. Among the 52 genes, 28 genes including nuclear factor I-X1 (NF1-X1), neuroligin 2 and 3, mitochondrial stress-70 protein (MTHSP70), neurodegeneration-associated protein 1 (Neurodap 1), multidrug resistance protein (MDR), and endoplasmic reticulum stress protein 72 (ERP72), were reported for the first time related to the manganese-induced neurotoxic-metabolism in the rat basal ganglia. According to the dose-related gene expression analyses, MTHSP70, Neurodap 1 and ERP72 genes were up-regulated compared to the control even in the group exposed to low manganese dose ( 0.2 ㎎/㎏ B.W./day). Conclusions: Twenty-eight genes detected for the first time in this study were closely related to the manganese-induced neurotoxic-metabolism in the rat basal ganglia and further study of these genes can give some more useful information about the manganese metabolism.