FCT 5 : Fractional laser-assisted topical imiquimod 5% cream treatment for recalcitrant common warts in children

( Hyun Chang Ko ),( Jeong Min Kim ),( Hyun Ho Cho1 ),( Won Jeong Kim ),( Je Ho Mun ),( Margaret Song ),( Hoon Soo Kim ),( Byung Soo Kim ),( Moon Bum Kim ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2

Background: Conventional destructive modalities for warts like cryotherapy or laser ablation have some limitations that are excruciating pain during procedure, in especially pediatric patients. Imiquimod is a topical immune response modifier that was approved for treating genital and perianal warts. But, thick stratum corneum of common warts may act as a barrier against drug permeation via the skin. Objectives: To evaluate efficacy and safety of above treatment. Methods: Eleven pediatric patients (6 female and 5 male, mean age 12.5 years) were included in this study. The lesions were treated by fractional 2940 nm Er:YAG laser for achieving the penetration of stratum corneum with 1 or 2 weeks intervals. Then, imiquimod 5% cream was self-applied once daily for 5 days a week. Assessment of response and adverse effects was performed every 2 weeks until complete clearance or up to maximum of 48 weeks. Pain during procedure was checked by VAS (0-10). Results: 8 out of 11 (72.7%) patients experienced complete clearance of all warts lesions. Mean duration of total treatment was 29.7 (16-48) weeks. Mean number of fractional laser treatment was 17.5 (8-37) times. No significant adverse effect was observed. VAS score of the pain during fractional laser treatment was 2.4 (1-4), comparing with 6.2 (5-8) during cryotherapy. Conclusion: Fractional ErYAG laser-assisted topical 5% imiquimod cream is an effective and safe treatment option for recalcitrant common warts of the children do not tolerate pain well.

최근 10년간 마취에 관한 임상적 고찰 (Ⅲ)

조현숙,김윤희,손수창,김혜자,최세진 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

To evaluate the specificity and the historical trends of the anesthetic agents and anesthetic methods used in Chungnam national university hospital, anesthetic experiences of 53,291 in total performed at Chungnam national university hospital from January 1987 to December 1996 were analized statistically and clinically according to age, sex, surgical department, physical status, elective to emergency surgery, premedicants, induction agents, anesthetic methods, main anesthetic agent, anesthetic technique and muscle relaxants. The results were as follows : L The number of cases has been steadily increased in annually. 2. The distribution of the number of patients according to the age were cases 37,309(70.02%) in the group of 13-60 years. 3. There were 27,448 male (51.5%) and 25,843 female (48.5%) cases. 4. 9,208 cases (17.27%) were OB-GY, 9,162 cases (17.19%) in general surgery, 7,936 cases(14.89%) in orthopedic surgery, and 6,079 cases (11.4%) in ENT in order of numbers. 5. According to the ASA classification of physical status , most of the cases were belonged to the class 1 (38.69%) class 2 (40.33%) class 1E (5.52%) class 2E (5.71%). Almost cases were relatively in good physical status. 6. The number of elective to emergency was 7,833 (89.76%), to 5,458 (10.24%) cases. 7. As premedicants, a group of glycopyrrolate (35.20%) was given most frequently. 8. Thiopental sodium has been mainly used for intravenous induction agent. 9. General anesthesia has been used as main method of anesthesia. 10. Enflurane was the most commonly used anesthetic agent. 11. Vecuronium was the most commonly used non-depolarizing muscle relaxant.

백워드 설계에 기반한 융합인재교육(STEAM) 프로그램 개발 및 적용

조수현,박창언 이화여자대학교 사범대학 교과교육연구소 2013 교과교육학연구 Vol.17 No.4

본 연구는 백워드 설계 모형에 기반한 과학 중심융합 인재 교육(STEAM) 프로그램의 개발과 적용 사례를 소개하는 것으로 초등학교에 적합한 융합인 재교육(STEAM) 방법을 논의하는 데 목적을 두고 있다. 본 연구의 연구 문제는 다음과 같다. 첫째, 백워드 설계에 기반한 초등 과학과 STEAM교육 프로그램은 어떻게 구성할 수 있는가? 둘째, 백워드 설계에 기반한 초등 과학과 STEAM교육이 학습자의 융합적 소양측면에서 어떠한 영향을 미치는가? 또한 본프로그램에 대한 교사들의 숙의는 어떠한가? 현재 국가정책적으로 융합인 재교육을 굉장히 강조하고 있는 추세이다. 이러한 현실에서 본 연구는 STEAM교육을 초등 일반 단위 학급 내에서 어떻게 효과적으로 구현될 수 있을지에 대한 고민으로부터 출발하여 STEAM 프로그램을 개발하고 실질적 운영 사례를 통해 STEAM교육 실천 가능성에 대한 경험적 논의를 시도하였다. 본 연구는 초등학교 3학년 동물 단원을 대상으로 한 초등융합 인재 교육 프로그램 개발 및 적용 연구로서 이해 중심설계 방식인 백워드의 원리와 Drake의 탈교과적 방법에 기초해 융합인 재교육 프로그램을 개발하였다. 또한 STEAM교육을 실행하고 있는 현장 교사들의 협의를 바탕으로 현장의 상황과 요구를 최대한 반영하여 프로그램을 개발하였다. 그리고 이를 직접 적용해 본 것을 학생들의 융합적 소양에 대한 검토뿐 아니라 실제 교사들의 숙의와 경험적 맥락에서 분석하고 논의하였다는데 의의가 있다. 이 연구를 통해 얻은 결과는 다음과 같다. 첫째, 본 프로그램의 효과를 알아보기 위해 실험반과 비교반의 사전․ 사후 융합적 소양검사를 해본 결과 감성적 체험, 창의적 설계, 내용 융합의 측면에서 STEAM을 적용한 실험 반 학생들의 결과가 비교반에 비해 높게 나타났다. 둘째, 본 프로그램 공개 수업후 교사협의 내용을 상황 제시, 창의적 설계, 감성적 체험의 세 가지 STEAM 요소 관점에서 분석해 본 결과 본프로그램에 대해 긍정적인 반응이 나타났다 This study introduces the development and application of S-STEAM education conducted with third-grade students in J elementary school. It suggests an ideal teaching/learning methodology for STEAM education suitable for elementary science and shares ideas about STEAM education. The focus of this study is the following. First, how could the STEAM program for science be organized based on backward design? Second, how would the students think and feel about the STEAM factors after the STEAM program? And, through deliberative procedures, how would teachers feel about a program based on STEAM? The most significant meaning about this program is that it was developed on a basis of teacher discussions and classroom situations, followed by incisive consultations about STEAM. The results are as follows. The effectiveness of this program was analyzed by students and teachers on a basis of three STEAM factors developed by the Korea Foundation for the Advancement of Science and Creativity. The program seems to be effective and meaningful for elementary science STEAM education. Two main methods were used: backward design that pursued an understanding of topics and a trans-disciplinary methodology. These provided the procedure for the organization of this program and were key to the success of the STEAM program that was developed in this study.

다수 영구치의 매복 및 맹출 지연의 교정치험례

조사현,양규호,김수지 大韓小兒齒科學會 1997 大韓小兒齒科學會誌 Vol.24 No.3

This report presents a case of adolescent patient who had multiple impacted teeth and no systemic disease, and was treated with removable and fixed orthodontic appliances. The results obtained through these cases were summarized as follows: 1. Even in the case without systemic disease, there can be the delayed eruption of multiple teeth. 2. If the root formation is not completed, root have no excessive curvature, axial inclination of the tooth is not excessive, and there is eruption space, the tooth can be induced to normal occlusion. 3. Since esthetically proper occlusion and dentition was acquired by recovery of the impacted teeth ot normal occlusion, the prosthodontic treatment after extraction of the impacted teeth was less needed. 4. This treatment brought psychological stability to pubertal patient who was interested in his facial profile.

Dehydroepiandrosterone과 노화

조수현 한양대학교 의과대학 1997 한양의대 학술지 Vol.17 No.1

There is an increasing evidence that dehydroepiandrosterone(DHEA) is an important mammalian steroid. Cancers. artherosclerosis, and dectease of immunloogical responses and brain function are frequently observed in aging. These changes in aging is accompanied by a progressive decline in the sectetion of the adrenal DHEA, the steroids at the highest concentration in the blood of young man. Until recently, no specific molecular or cellular target of DHEA has been described. However, the mode of action of DHEAprobably involved two series of mechanisms : 1) transformation of DHEA into active sex steroids(andregen, esterogen) that promote overall anabolic effects in several tissue, and 2) effects in the central nervous system through an inhibition of the GABAA receptor and a potentiator of NMDA and sigma receptor function. In the last few years, striking effects of DHEA has been obtained mostly in animal experiments. The preventive and/ or therapeutic activity of DHEA has been reported for the development of arte-rial lision, diabetes, cancer, infection and improvement of physical and psychological well-being. A steroid without(up to now)a proper selective receptor, and acting in part through metabolites, DHEA is not a typical hormone. At present there is only the intention of relieving, for as long as ossible, some of damage caused by aging within the framework of research based on physionlogical data and under medical surveillance. Several years will be necesary to pass from precise and limited observations to al sure, dfficacious DHEA useable by many people.

황토 급여가 거세한우의 발육에 미치는 영향

조원모,기광석,정하연,강수원,김준식,백봉현,김용국 한국국제농업개발학회 2003 韓國國際農業開發學會誌 Vol.15 No.1

본 연구는 거세한우 육성우에 대한 황토 첨가급여가 발육에 미치는 효과를 구명하고자 발육능력, 사료섭취량을 규명한 바 아래와 같은 결과를 얻었다. 전 시험기간 동안의 평균 일당증체량은 대조구와 황토급여구가 각각 0.91㎏과 0.87㎏/day로 대조구가 높은 것으로 나타났지만 유의성은 인정되지 않았다. 사료섭취량은 대조구와 황토급여구 모두 평균 일일 두당 농후사료 섭취량이 2.42㎏이었으나, 건초섭취량에 있어서는 각각 3.02와 3.14㎏으로 황토급여구가 다소 높은 경향으로 나타났다. The study was conducted to investigate the effect of dietary supplements of reddish clay on the growth performance in growing Hanwoo steers. A total of 8 calves was allocated into 2 feeding groups, control(basal diet) and treatment(basal diet plus ad libitim Reddish clay) for Hanwoo steers. This study was carried out for 5 months with a total of 8 calves. The results obtained in the present studies are summarized as follows : Average daily gains throughout the experimental period of 4 months to 9 months of age were 0.91 and 0.87㎏ for control group and reddish clay-supplemented group, respectively, however, no statistical significances were found. Average daily intake of concentrates was 2.42㎏ for each group, while that of hay tended to be higher in reddish clay-supplemented group(3.14㎏) than in control group(3.02㎏).

적절한 용량 이하의 경구용 향응고제 사용 중 발생한 뇌출혈 환자의 임상 양상

조수진,황흥곤,나찬영,이영탁,최현배,조태구 世宗醫學硏究所 2000 世宗醫學 Vol.17 No.2

연마 다듬질 가공면의 표면 미세형상 평가에 관한 연구

조남규,김현국,권기환,한창수,안유민,이성환,박균명 한국공작기계학회 2000 한국공작기계학회 추계학술대회논문집 Vol.2000 No.-

This paper describes the statistical analysis techniques for the surface roughness assessment of polished surfaces. In experiments, the polishing process of the sample surfaces which are manufactured by ball end mill is consist of two steps; the cusp removal process and the surface finishing process. For the cusp removal process, the criterion of cusp removal was established from the power spectrum analysis to assess the change of the cusp removal rate. For the finishing process, the surface was polished by the rotational CBN tool and vibration wood tool. And the surface quality of polished surface was assessed using the functional parameters based on the statistical values of surface profiles. Consequently, the surface finish performance of the polished surface using the vibration wood tool was improved.

야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

슈만의 피아노작품「크라이스레리아나, op.16」과 E.T.A.호프만의 소설「카터 무어」에 나타난 구조적 연관성

조현수 명지대학교 예체능연구소 1999 藝體能論集 Vol.10 No.-

The Relationship between literature and music implied in R.Schumann's Kreisleriana provides performers with specific clues to understanding the content of the music. It is thought that E.T.A. Hoffmann's novel, Kater Murr might have influenced Schumann when he wrote Kreisleriana. They share the similar structure and character. The purpose of this paper is to compare Kreisleriana with Kater Murr in order (1) to understand how the music is structured as a unified cycle even though it is often fragmentary, and includes abrupt contrasts, and (2) to discover how Schumann associated particular compositional techniques with different kinds of emotional expression or character portrayal.