고요산혈증의 위험인자 : 아산시 지역 주민을 대상으로

김용배,장원기,황보영,김화성,안규동,이병국,이용진,이종은,이준숙,이찬구,이한정,이성수 순천향대학교 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1

Objective : Serum uric acid has now been identified as a marker for a number of metabolic and hemodynamic abnormalities. The aim of this study is to evaluate risk factors which influence hyperuricemia in the citizens of Asan. Method : The study design was cross-sectional and research subjects were 1086 citizens of Asan. General characteristics, cigarette smoking, alcohol consumption, and past history were obtained by interview using a structural questionnaire. Also, we measured height, weight and blood pressure, and serum uric acid of the subjects. Results : The mean serum uric acid level was 5.27 ㎎/㎗ in men and 4.01 ㎎/㎗, in women, In the multiple logistic regression analysis, statically significant risk factors of hyperuhcemia were gender, body mass index, blood lead concentration, and serum creatinine. Conclusion : Our results suggest that gender, body mass index, blood lead concentration, and serum creatinine might be the most important risk factors of hyperurcemia. Education program as well as routine check-up for serum uric acid was highly recommended for the effective prevention of hyperuricemia.

Safety of subtotal or total colectomy with primary anastomosis compared to Hartmann procedure for left-sided colon cancer obstruction or perforation

Eun-Do Kim,Jin-Kwon Lee,Jin-Kyu Cho,Jae-Myung Kim,Ji-Ho Park,Ju-Yeon Kim,Sang-Ho Jeong,Young-Tae Ju,Chi-Young Jeong,Eun-Jung Jung,Young-Joon Lee1,Soon-Chan Hong,곽승진 대한종양외과학회 2019 Korean Journal of Clinical Oncology Vol.15 No.2

Purpose: Whether subtotal or total colectomy with primary anastomosis (PA) is safer than Hartmann procedure (HP) for left-sided colon cancer obstruction or perforation remains controversial. The purpose of this study was to compare postoperative morbidity, mortality, and defecation frequency between PA and HP for left-sided colon cancer obstruction or perforation. Methods: This retrospective study enrolled 54 patients from January 2014 to February 2018 who underwent emergency surgery due to left-sided colon cancer obstruction or perforation. Results: PA was carried out in 20 patients while HP was performed for 34 patients. Thirty-day mortality did not show significant difference between the two groups (15.0% vs. 14.7%, P=1.000). No anastomotic leakage occurred in PA group while three (8.8%) cases of stump leakage occurred in HP group. Stoma repair was performed for 13 cases (44.8%) and stoma reformation was performed for one case in HP group (7.7%). Stoma related complications occurred in five cases (17.24%). For patients after stoma repair, defecation frequency at 3 months after operation was 2.91±2.88 times per day in PA group and 2.86±2.63 times per day in HP group. At 1 year after operation, defecation frequency was changed to 1.40±1.12 times per day in PA group and 1.17±0.39 times per day in HP group. Conclusion: Primary ileosigmoid or ileorectal anastomosis for left-sided colon cancer obstruction or perforation is safe, and shows similar outcome of defecation frequency compared to H

직업적 연폭로가 일부 신경행동학적 검사수행에 미치는 영향

안익수,안현철,김용배,리갑수,김화성,황규윤,최은,장봉기,이성수,안규동,이병국 순천향대학교 산업의학연구소 1999 순천향산업의학 Vol.5 No.1

In order to investigate that blood lead levels of lead exposed workers is associated with decreased performance in neurobehavioral tests in adults, we investigate 78 workers in a battery industry. Three items among neurobehavioral core test battery of World Health Organization, including digit span, Santa ana dexterity, digit symbol were administered to workers occupationally lead exposed workers by operational guide for the WHO neurobehavioral core test battery. Blood lead (PbB) and zinc protoporphyrin in whole blood (ZZP) were selected as an index of lead exposure. Detailed occupational history such as exposed agent, age, work duration, smoking and drinking habits, were recorded as confounding factors. After controlling age, the results of digit span and digit symbol among the neurobehavioral tests were significant contributed by PbB.

생선 가시로 인한 소장 천공 및 복강내 농양 1예

문성수,이수형,이은아,박성한,이준식,홍현진,신은경,김규종 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.1

A variety of swallowed foreign bodies are seen in gastrointestinal tract. However 80-90% of objects usually pass spontaneously through the alimentary tract and out in the feces and 10-20% removed without complication endoscopically. Therefore about less than 1% of foreign bodies ingested only require surgery due to complications, such as perforation, obstruction. Perforation of the gastrointestinal tract is a well-recognized complication of the foreign body ingestion. The most common site is ileum. Unfortunately, the diagnosis of small-bowel perforation by foreign bodies is rarely made preoperatively because the clinical symptoms are usually nonspecific or mimic other surgical conditions, such as appendicitis, diverticulitis, and perforated peptic ulcer etc. We report here a rare case of the small bowel perforation with mass-like intraabdominal abscess by fishbone ingestion in 59-year-old man who presented with a non-tender palpable mass in the left paramedian area and underwent abdominal computer tomography initially reported as showing intraabdominal mass.

중추성 요붕증이 동반된 랑게르한스 세포 조직구증 1예

김진호,문준성,문선중,이지은,최재원,은미정,천경아,조인호,윤지성,원규장,이경희 신덕섭,이형우 영남대학교 의과대학 2005 Yeungnam University Journal of Medicine Vol.22 No.2

Central diabetes insipidus (DI) is a syndrome characterized by thirst, polydipsia and polyuria. Langerhans cell histiocytosis is one of the etiologies of DI. Recently we experienced a central DI associated with Langerhans cell histiocytosis. The 44 years old female patient complained right hip pain polydipsia and polyuria. We carried out water deprivation test. After vasopressin injection, urine osmotic pressure was increased form 109mOsmol/Kg to 327mOsmol/Kg (300%). Brain MRI showed a thickened pituitary stalk and at hot bone CT.CT guided biopsy revealed abnormal histiocytes proliferation and abundant lymphocytes, The final diagnosis was central DI associated with systemic Langerhans cell histiocytosis invading hip bone, L-spine and pituitary stalk. Desmopressin and etoposide chemotherapy were performed to the patient.

한국 정신장애의 역학 조사 연구[I] : 각 정신장애의 유병률

조맹제,함봉진,김장규,박강규,정은기,서동우,김선욱,조성진,이준영,홍진표,최용성,박종익,이동우,이기철,배재남,신정호,정인원,박종한,배안,이충경 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.4

Objectives : This study aims to estimate the prevalence of the DSM-IV psychiatric disorders in Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI). Methods : Subjects were selected by taking multi-stage, cluster samples of 7,867 adult household residents, 18 to 64 years of age, in ten catchment areas. Total 78 trained interviewers administered the K-CIDI to the selected respondents, from June 1 to November30,2001. Results : Total 6,275 respondents completed the interview. Some 33.5% of respondents reported at least one lifetime disorder, 20.6% reported at least one-year disorder, and 16.7% reported at least one-month disorder. The most common lifetime disorders were alcohol abuse/dependence (17.24%), nicotine dependence/withdrawal (11.19%), specific phobia (5.16%), and major de-pressive disorder (4.25%). The lifetime prevalence of substance abuse/dependence (0.25%) and schizophrenia (0.16%) was very low. Nicotine and alcohol use disorder showed very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among female than male. Conclusion : The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in distributions of psychiatric disorders across the areas and times were observed.

중년여성의 우울, 신체증상 및 자아 존중감간의 관계

이규은 關東大學校 醫科大學 醫科學硏究所 1999 關東醫大學術誌 Vol.3 No.1

The purpose of this study was to investigate the relationship between depression, soimatic discomfort and self-esteem in middle-aged women. The subjects for this study were 246 middle-aged women. Data were collected from February 22 to April 24, 1999 by structured questionnaire. The instruments for this study dele CES-D(Radloff, 1977), somatic discomfort scale(Wittenborn, 1979) and self-esteem scale(Rosenburg, 1971). The data were analyzed SAS/PC program using descriptive statistics, ANOYA, Pearson correlation coefficient. The result of this study ere as follows: 1. The mean age of the subjects were 46.79 years. 2. The statistically significant difference in the score of the depression according to the age(F=3.46, p=.0049) and perceived health status(f= 7.11, p=.001) was obtaind. 3. The statistically significant difference in the level of soimatic discomfort according to the age was obtained muscular discomfort(F=4.11, p=.001). autonomic discomfort(F'=3.15, p=.0059), gastric discomfort(F= 3.16, p =.0089), wakefulness(F=2.69, p=.0218), eyes(F=3.30, p=.0066), climacteric discomfort(F=5,48, p=.0001), cold(F=2.33, p=.0433). 4. The somatic discomfort significantly different according to the level of education were muscular discomfort (F=7.46, p=.0001), autonomic discomfort(F=·1.55, p= .0015), intestinal discomfort(F=3.31, p=.0115), gastric discomfort(F=5.09, p=.0006), wakefulness(F=4.31, p=.0022), dry mouth(F=5.21, p=.0005), climacreric discomfort(F=3.65, p=.0063), cold (F=3.61, p=.0071). 5. The somatic discomfort significantly different according to the job were cutaneous discomfort (F=5.36, p =.0214), cold(F=3.90, p=.0493), fatigue(F=6.20, p=.0133), and others(F=4.65, p=.0,120). 6. The somatic discomfort significantly different according to the perceived health status were muscular discomfort (F=15.39, p=.0001), autonomic discomfort(F=4.80, p=.0010), circulation(F=7.74, p=.0001), intestinal discomfort (F=6.48, p=.0001), gastric discomfort(F= 14.00, p=.0001), wakefulness(F=4.57, p=.0014), eyes(F=B.49, p=.0095), rhinitis(F=6.22, p=.0001), menstrual discomfort (F=6.11, p=.0001), dry mouth(F=,3.59, p=.0073), climacteric discomfort(F=8.45, p=.0001), constipation(F=3.38, p=.0103), cold(F=4.47, p=.0017), fatigue(F=15.94, p=.0001), and others(F=3.56, p=.0076). 7. The statistically significant difference in the self-esteem according to the presence of Job(F=5.61, p=.0187) and perceived health status(F= 3.24, p=.0131) was obtined. 8. There were high correlation between depression and somatic discomfort(r=.4856, p=.0001), between depression and self-esteem(r=-.4200, p=.0001), and between somatic discomfort and self-esteem(r=-.2275, p=.0015).

대학생들의 성인성 질환(STD)에 대한 지식

이규은 관동대학교 의과학연구소 2006 關東醫大學術誌 Vol.10 No.1

전립선 비대 증상 자각군과 일반 남성군의 전립선 비대 증상, 일상생활 활동, 성생활 만족 및 안녕감 비교

이규은,오점숙,김현주,김남선 성인간호학회 2003 성인간호학회지 Vol.15 No.3

Purpose: This study was designed to explore and compare the prostatic hypertrophoc symptoms, activities of daily living, satisfaction of sexual activities and well-being among subjects with prostatic hypertrophic symptoms and the general population. Method: One hundred subjects with prostatic hypertrophic symptoms and one hundred general persons were recruited in K medical center. The data were collected from October 20, 2001 to March 30, 2002 by structured questionnaire. Result: The results were the following; 1. The percentage of mild(0~7), moderate(8~19) and severe(20~35) symptoms between subjects with prostatic hypertrophic symptoms and general persons were 6% : 60%, 54% : 39%, 40% : 1%. 2. There was a significant difference in prostatic hypertrophic symptoms(t=12.82, p<.001), in activities of daily living(t=-7.77, p<.0001), in satisfaction of sexual activities (t=-4.80, p<.0001), in well-being(t=-4.80, p<.0001) between subjects with prostatic hypertrophic symptoms and general persons 3. There was a significant difference in activities of daily living(F=16.28, p<.0001), satisfaction of sexual activities(F=3.98, p<.05) according to prostatic hypertrophic symptoms in subjects with prostatic hypertrophic symptoms. Conclusion : According to the above findings, prostatic hypertrophic symptoms influence activities of daily living, satisfaction of sexual activities, well-being of subjects with prostatic hypertrophic symptoms negatively.

진부지역에서 생산된 당귀를 이용한 추출물 제조 및 이화학적 특성

이원종,윤정로,김은경,안규태 강릉대학교 동해안지역연구소 2000 東海岸硏究 Vol.11 No.1

추출조건 (온도, 추출시간, 용매의 농도)에 따라 당귀의 특유성분인 decursin의 함량을 측정하였으며, 산지별로 당귀를 수집하여 추출물을 제조한 후 이화학적 성질을 조사하였다. 물, ethanol, methanol, chloroform, benzene, ether등으로 추출한 결과, 당귀의 지표물질인 decursin은 물로는 잘 추출되지 않았고 고농도의 ethanol로 추출하는 것이 가장 효과적이었다. 당귀의 ethanol 추출물 제조시 ethanol의 농도는 95%, 추출온도는 60℃, 추출시간은 4시간이 가장 적합하였다. 진부지역에서 생산된 일당귀 및 일본산 당귀의 decursin 함량은 0.2-0.5%이었고, 중국산 당귀는 1.1%를 함유하였으며 진부산 토당귀는 6.2%를 함유하였다. 진부산 토당귀와 일당귀, 중국산, 일본산 당귀를 열수 추출물, ethanol 추출물을 제조한 결과, 열수 추출물은 ethanol 추출물보다 단백질과 회분을 많이 함유하였으며, ethanol 추출물은 지질을 많이 함유하였다. Chemical components and decursin contents of Angelica gigas Nakai (Korean), Angelica acutiloba Kitagawa (Korean and Japanese), and Angelica sinensis Diels (Chinese) were analyzed. Angelica gigas Nakai (Korean) contained the highest amount of decursin with 6.2%, while Angelica acutiloba Kitagawa (Korean and Japanese) contained only 0.2-0.5% decursin and Angelica sinensis Diels (Chinese) contained 1.1% decursin. Angelica gigas Nakai (Korean) was extracted under various conditions and evaluated for decursin content. The decursin content of extracts was the highest when extracted with 95% ethanol at 60℃ for 4 hours. Angelica gigas Nakai was extracted with water and 95% ethanol and physicochemical properties of extract were analyzed, The extraction yield. protein content, and ash content were high when using the water as an extraction solvent; while, crude lipid was high when using the 95% ethanol as the extraction solvent.