노인의 영적 간호요구

최미혜,김경희,김귀옥,김기숙,김수강,김정신,김춘숙,노흥진,박지연,성혜연,오명선,이선희,이원옥,이윤영,이현수,장명재,차혜경,채정선,홍상희 중앙대학교 의과대학 간호학과 간호과학연구소 2001 중앙간호논문집 Vol.5 No.1

This study was designed to exam the aged's needs for spiritual nursing care. The purpose was to serve as a basis for the development of spiritual nursing practice. The major findings are as follows : 1. The degree of needs for spiritual nursing care as area was that needs of love and relationship mean 22.0, needs of meaning and object mean 28.2, needs of forgiving mean 13.5. Total needs for spiritual nursing care mean 63.7, which was on the upper middle level. The needs of meaning and object was rated highest. 2. Among the general characteristics of the subjects, needs of love and relatiohship wasn't significanlty different. 3. Among the general characteristics of the subjects, needs of meaning and object was significantly different according to two factors : age(F=7.260, p=0.001), religion(F=5.275, p=0.001). Higher needs of meaning and object was possessed by the older than the younger, by the one who have religion than the other. 4. Among the general characteristics of the subjects, four factors made a significantly difference to needs of forgiving : sex(t=-2.851, p=0.006), age(F=8.201, p=0.001), religion(F=6.928, p=0.000), disease(t=2.327, p=0.024). Higher needs of forgiving was possessed by man than woman, by the older than the younger, by the one who have religion than the other, by the one who have disease than the other.

Lysophosphatidic acid increases mesangial cell proliferation in models of diabetic nephropathy via Rac1/MAPK/KLF5 signaling

Kim, Donghee,Li, Hui Ying,Lee, Jong Han,Oh, Yoon Sin,Jun, Hee-Sook Nature Publishing Group UK 2019 Experimental and molecular medicine Vol.51 No.2

<▼1><P>Mesangial cell proliferation has been identified as a major factor contributing to glomerulosclerosis, which is a typical symptom of diabetic nephropathy (DN). Lysophosphatidic acid (LPA) levels are increased in the glomerulus of the kidney in diabetic mice. LPA is a critical regulator that induces mesangial cell proliferation; however, its effect and molecular mechanisms remain unknown. The proportion of α-SMA<SUP>+</SUP>/PCNA<SUP>+</SUP> cells was increased in the kidney cortex of <I>db/db</I> mice compared with control mice. Treatment with LPA concomitantly increased the proliferation of mouse mesangial cells (SV40 MES13) and the expression of cyclin D1 and CDK4. On the other hand, the expression of p27<SUP>Kip1</SUP> was decreased. The expression of Krüppel-like factor 5 (KLF5) was upregulated in the kidney cortex of <I>db/db</I> mice and LPA-treated SV40 MES13 cells. RNAi-mediated silencing of KLF5 reversed these effects and inhibited the proliferation of LPA-treated cells. Mitogen-activated protein kinases (MAPKs) were activated, and the expression of early growth response 1 (Egr1) was subsequently increased in LPA-treated SV40 MES13 cells and the kidney cortex of <I>db/db</I> mice. Moreover, LPA significantly increased the activity of the Ras-related C3 botulinum toxin substrate (Rac1) GTPase in SV40 MES13 cells, and the dominant-negative form of Rac1 partially inhibited the phosphorylation of p38 and upregulation of Egr1 and KLF5 induced by LPA. LPA-induced hyperproliferation was attenuated by the inhibition of Rac1 activity. Based on these results, the Rac1/MAPK/KLF5 signaling pathway was one of the mechanisms by which LPA induced mesangial cell proliferation in DN models.</P></▼1><▼2><P><B>Kidney disease: Mechanisms of diabetes-related damage</B></P><P>A potent molecular mediator of diabetic kidney disease induces its pathogenic effects via proteins that could be targeted with future drug therapies. Yoon Sin Oh
from Eulji University in Seongnam-si and Hee-Sook Jun from Gachon University in Incheon, both in South Korea, and colleagues treated certain cells found in the kidney’s glomerulus, the organ’s filtering unit, with a signaling molecule called lysophosphatidic acid (LPA) that is elevated in the blood of diabetic mice. They showed that LPA stimulated cellular proliferation and boosted the expression of proteins involved in regulating the cell cycle and a multipurpose signaling pathway. They then inhibited the activity of these proteins to prevent the kidney cells’ hyperproliferation, both in cell culture and in diabetic mice. The results highlight the potential of blocking mediators of LPA signaling to treat kidney-related complications of diabetes.</P></▼2>

관상동맥 스텐트 내 재협착의 발생에 미치는 임상적 관동맥 조영술적 요인들

윤혁준,김기식,박형섭,이영수,현대우,한성욱,허승호,김윤년,김권배,박남희,원경숙 대한순환기학회 2003 Korean Circulation Journal Vol.33 No.12

노인요양시설 거주노인의 생활만족도

윤숙희 인제대학교 2010 仁濟論叢 Vol.25 No.1

This study aims at providing high quality of nursing care to improve life satisfaction for the elderly in nursing home. A sample consisted of 92 older residence from 6 nursing home located in Busan and GyeongNam province, The data were collected during Aug, 2009, A self-administered questionnaire was used to assess socio-demographics, life satisfaction, The total score of life satisfaction of the elderly in nursing home was 13.75(±5.38). The general characteristics related to life satisfaction were gender, age, spouse, monthly allowance, education, health condition, length of stay in nursing home, The development of supportive program for increasing life satisfaction of the elderly is needed in nursing home.

임상간호사의 직무스트레스와 우울 : 한국인 직무스트레스 측정도구를 이용하여

윤숙희 대한간호학회 간호행정학회 2009 간호행정학회지 Vol.15 No.3

Purpose: The purpose of this study was to examine the level of occupational stress and depression in clinical nurses and to investigate the effects of subscales of occupational stress on depression. Method: A sample consisted of 202 nurses from 6 hospitals located in Busan and GyeongNam province. The data were collected from November 2008 to march 2009. A self-administered questionnaire was used to assess socio-demographics, job characteristics, depression measured by Korean CES-D, and occupational stress assessed by KOSS. Result: The total score of occupational stress in clinical nurses was within bottom 25%, but the scores of 'Difficult physical environment', 'High job demand', 'Inadequate social support', 'Organizational injustice' were within top 50%. The 8 subscales of occupational stress had significantly effects on clinical nurses' depression after controlling for age, marital status, type of hospital, current position. Conclusion: The administration of employee assistance program for management occupational stress is important for decreasing depression in clinical nurses.

간호사의 직무스트레스와 노인에 대한 지식, 태도 및 케어실천행위

윤숙희 대한간호학회 간호행정학회 2009 간호행정학회지 Vol.15 No.4

Purpose: This study was to examine the relation of nurses' job stress and knowledge, attitude and care behavior for elderly patient in hospitals. Method: One hundred ninety one nurses caring the elderly patients in hospitals in Ilsan, Busan and Gyeongsangnam-do were subjects. The data was collected between Sept. 21 and 31, 2009. Data was analyzed using t-test, ANOVA, Pearson correlation with SPSS/Win 17.0 and the fitness of pathway models with AMOS 5.0. Results: The mean scores of job stress and knowledge were in middle range, and attitude and care behavior were in a little higher range. The fitness of hypothetical model was excellent. Job stress had direct effects on attitude and care behavior, knowledge had direct effect on attitude and attitude had direct effect on care behavior. But the pathways related to job stress and attitude and job stress and care behavior were not significant. In modified model deleted the pathway between job stress and attitude, the pathway related to job stress and behavior also was not significant. Conclusion: Education related to the elderly for nurses to improve care behavior is needed continuously.

뇌졸중 환자 가족의 돌봄의 경험 : 현상학적 연구

윤숙희 인제대학교 1995 仁濟論叢 Vol.11 No.2

The concept of the family burden for helping patients in the hospital as well as in the home setting has been raised as a nursing issue recently Those who survive stroke are discharged to home disabled and the responsibility for providing adequate care to the patient has fallen primarily on family members. Therefore this study using phenomenologic approach was carried out to explore and explain the experiences of family caregivers of stroke. The informants of the study were 5 family caregivers caring for the patients with stroke at hospitals or their homes. The study was conducted from Novembers 1995 through January, 1996. Data were collected through in-depth interviews, telephone interviews and narrative data. Data collection and analysis were conducted concurrently. Analysis method of data was Giorgic method. According to the results, caregiving has been associated with emotional crisis, physical discomfort, guilty feeling, anxiety, feeling of social isolation and depression. This study offers better understanding on the caregiving experiences and may facilitate more appropriate interventive strategies.

진공포장 우육의 포장 개봉 후 냉장에 의한 아미노산 함량 변화

김미숙,문윤희 慶星大學校 1999 論文集 Vol.20 No.2

This study was conducted to investigate effect of chilling, and rechilling at 1℃ for 3 days after open pack on the free amino acid of vacuum packaged beef in Holstein Cow. The chilled beef was stored at 1℃ for 3 days after 2 days postmortem and the rechilled beef was chilled for 3 days after open pack. In case of total amount of free amino acid, the chilled beef was increased to 35.7% by the chilling process, and by the rechilling process, 20, 40, and 60 days rechilled beef were increased to 24.1%, 34.4% and 37.8%, respectively. Ratio of serine, glutamic acid, glycine, valine, isoleuicine, phenylalanine, histidine, and proline contents in chilled beef were increased by chilling process, but decreased another amino acid. Ratio of acidic, neutral and hydroxy amino acid/total amino acid content of chilled beef were increased by chilling process. By the rechilling process, ratio of serine and arginine contents of total amino acid in rechilled beef were increased, regardless of storage period. Ratio of neutral amino acid content of total amino acid in rechilled beef was decreased by rechilling process, but hydroxy amino acid was increased, regardless of storage period. Also, the amount of aromatic amino acid was increased by the rechilling process after the 20 days only.

유아 영재의 정서지능과 지능, 창의성과의 관련성 탐색

황희숙,강승희,윤소정 한국영유아보육학회 2004 한국영유아보육학 Vol.0 No.37

The purposes of this study were: 1) to investigate developmental trends in young gifted children's emotional intelligence used the emotional intelligence rating scale for preschool children(Kim, 1998). 2) to investigate the relationship between young gifted children's emotional intelligence, intelligence and creativity. Subjects for this study were 36 young gifted children, 4 to 6 years of age. To analyze the relationship between emotional intelligence, intelligence and creativity, three instruments were used: The Emotional Intelligence Rating Scale for Preschool Children, The Korean Wechsler Preschool and Primary Scale of Intelligence(K-WPPSI) and Torrance Test of Creative Thinking(TTCT). The result from this study were as follows: First, significant age and gender differences were not found in emotional intelligence. Second, there were no significant differences between emotional intelligence and intelligence, and emotional intelligence and creativity.

버섯의 자외선조사와 조리조건에 따른 Vit.D_2 와 Vit.B_2 함량의 변화

박희옥,오혜숙,윤선 한국식생활문화학회 2001 韓國食生活文化學會誌 Vol.16 No.5

This study was to investigate the effect of ultraviolet rays, soaking, boiling and baking to ergocalciferol(Vit.D_2) and riboflavin(Vit.B_2) contents of mushrooms, Lentinus edodes, Pleurotus ostreatus and Agaricus bisporus. The results were as follows: 1. Mushrooms were exposed to ultraviolet rays, Lentinus edodes : 10J/㎠, Pleurotus ostreatus : 2J/㎠ and Agaricus bisporus : 2J/㎠. 2. Before exposing to ultraviolet rays, the ergocalciferol contents of mushrooms were all 0㎍/g dry base, but after exposing to it , those of Lentinus edodes, Pleurotus ostreatus and Agaricus bisporus were 222.50±5.30㎍/g dry base, 150.90±6.60㎍/g dry base and 23.98±1.20㎍/g dry base, respectively. 3. Before and after exposing to ultraviolet rays, the riboflavin contents of Lentinus edodes, Pleurotus ostreatus and Agaricus bisporus were 18.22±0.71㎍/g dry base and 11.72±0.50㎍/g dry base, 4.57±0.20㎍/g dry base and 3.26±0.15㎍/g dry base, and 37.42±1.20㎍/g dry base and 27.33±2.10㎍/g dry base, respectively. 4. The ergocalciferol contents of mushrooms according to boiling time were not significantly different but the riboflavin contents of them were decreased according to the increase of boiling time. 5. The ergocalciferol and riboflavin contents of mushrooms were decreased according to the increase of NaCl concentration and baking temperature. 6. The ergocalciferol content of Lentinus edodes after a short time soaking at 80℃ was higher than a long time soaking at 20℃, 40℃ and 60℃.