진공포장이 냉장돈육의 지질산화 및 육색에 미치는 영향

양종범,고명수,문윤희 한국식품영양학회 2002 韓國食品營養學會誌 Vol.15 No.1

진공포장이 냉장 돈육의 지질산화 및 육색에 미치는 영향을 조사하기위해 돈육의 등심부위를 진공포장한 후 30일 동안 4℃에서 냉장저장하면서 저장기간에 따라 TBA가, pH, 홍색화 시간 및 CIE L^*a^*b^*값의 변화를 측정하였다. TBA가 랩포장육의 경우 저장 7일 이후에 급격히 증가되었으나, 진공포장육은 저장 30일까지 낮은 수준으로 유지되었다. pH도 랩포장육의 경우 저장 7일 이후에 급격히 증가되었으나, 진공 포장육은 저장말기까지 매우 완만하게 증가되었다. CIE a*값과 반사도의 측정 결과 진공포장육의 홍색화 시간은 포장 개봉 후 30분이었다. 따라서 진공포장 개봉 직후와 개봉 30분 후에 CIE L^*a^*b^*값을 측정하여 랩포장육과 비교하였다. CIE L*값은 랩포장육의 경우 저장 7일부터 급격히 감소되었으나, 진공포장육은 개봉 직후의 경우 저장말기까지 점차 증가되는 경향이었으며, 개봉 30분 후의 경우 개봉 직후보다 약간 높거나 큰 차이가 없었다. CIE a^값은 랩포장육의 경우 저장 7일까지 점차 증가되었고 그 후 급격히 저하되었으나, 진공포장육은 개봉 직후의 경우 저장초기에는 랩포장육보다 매우 낮은 수준이었고, 저장기간이 경과됨에 따라 점차 증가되었으며, 개봉 30분 후의경우 개봉 직후보다 전반적으로 높은 수준이었다. CIE b^*값은 랩포장육의 경우 저장 4일째에 크게 증가되었고 그 후 급격히 저하되었으나, 진공포장육은 개봉 직후의 경우 랩포장육은 매우 낮은 수준이었고, 저장기간이 경과됨에 따라 완만하게 증가되는 경향이었으며, 개봉 30분 후의 경우 개봉 직후보다 매우 높은 수준으로 유지되었다. This study was conducted to investigate the effects of vacuum packaging on lipid oxidation and meat color of chilled pork. During storage meats were evaluated for TBA values, pH, blooming time and CIE L^*a^*b^* values. The TBA values of wrapped meats increased rapidly after 7days and those of vacuum packaged meats maintained at low level up to 30 days of storage. The pH of wrapped meats increased rapidly after 7days, while those of vacuum packaged meats increased slowly up to 30 days of storage. The bloom time of vacuum packaged meats was 30 min after opening. the CIE L values of wrapped meats decreased rapidly on the 7th day, while those of vacuum packaged meats directly after opening decreased slightly up to 7days of storage and thereafter increased gradually. The CIE *a values of wrapped meats increased gradually up to 7days and thereafter decreased rapidly, while those of vacuum packaged meats directly after opening were lower than those of wrapped meats. The CIE a^* values of vacuum packaged meats after 30 min in the air were higher than those of vacuum packaged meats directly after opening. The CIE b^* values of wrapped meats increased rapidly on 4th day and thereafter decreased rapidly, while those of vacuum packaged meats directly after opening were lower than those of wrapped meats. CIE b^* values of vacuum packaged meats after 30 min in the air were higher than those of vacuum packaged meats directly after opening.

최근 8년간 K지방대학병원 응급실로 내원한 치과 응급환자에 관한 임상적 연구

유재하,김종배,김태우,문선재,권혁찬,김승범 大韓顎顔面成形再建外科學會 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.6

The delivery of the proper care to the emergency dental patients is more important in the aspdect of community dental service. To attain such a purpose requires the sacred duty to the training of oral and maxillofacial surgeons. This is a retrospective study on the characteristics of dental injuries and diseases in emergency patients. Ths study was based on a series of 2,649 patients treated as dental emergency patients at K country hospital of medical college, from Jan. 1, 1993, to Dec. 31, 2000. The obtained results were as follows. The trauma(71.6%) was the most frequent cause in dental emergency patients, odontogenic infection and oral hemorrhage were next in order of frequency. The primary interdental wiring and transpalatal wiring were frequent proper methods with rubber drainage for prevention of hemorrhage and infection in the primary care of jaw fracture. The peak incidence(45.0%) about the infection group was occurred in the pulpitis of advanced dental caries, and common treatments were the medication of antibiotics & anagesics and I&D. In the dentoalveolar hemorrhage group, a major cause was postoperative hemorrhage(57.9%) and hemostasis was obtained by pressure dressing, suture and drainage of infected wound. About TMJ disorder group, the peak incidence was showed in the post-traumatic myofascial pain dysfunction syndrome and its primary care was medications(anagesics & sedatives). In the other groups, various irritable specific pains were complained, such as trigeminal neuralgia-form pain, acute stomatitis, chemical burn, terminal stage neuritis of head & nech cancer and their primary care methods were various individually. For the rapid and correct care of the emergency dental disease above, well-trained education should be presented in the intern and resident curriculum of oral & maxillofacial surgery.

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

우리나라 영아에서 주사용 소아마비 백신(Poliorix^TM)의 안전성 및 이상반응에 대한 연구

Sin, Jong Beom,Park, Moon Sung,Ma, Sang Hyuk,Choi, Young Youn,Shin, Son Moon,Kim, Won Duck,Kuriyakose, Sherine,Ulianov, Liliana,Hardt, Karin The Korean Society of Pediatric Infectious Disease 2013 Pediatric Infection and Vaccine Vol.20 No.3

목적: 한국은 2000년에 소아마비 무발생국가로 공인되었으며, WHO의 권고에 의해 2005년부터는 경구용소아마비 생백신 대신 주사용 사백신을 사용하기 시작했다. 본 연구는 2006년부터 국내에서 사용되기 시작한 주사용 소아마비 백신(Poliorix$^{TM}$)의 안전성 및 이상반응을 우리나라 영아들을 대상으로 알아보고자 한다. 방법: 2006년부터 2012년까지 6년 동안 다기관공동연구로 조사하였으며, 2, 4, 6개월의 기초접종과 4-6세의 추가 접종 후 7일 이내 및 31일 이내의 이상반응 및 안전성에 대해 조사하였다. 결과: 총 639명 중 등록대상자 중 617명은 기초접종, 22명은 추가접종을 실시하였으며, 639명 중 73명(11.4%)에서 명시되지 않은 이상반응을 보고하였으며, 이중 가장 많은 증상은 상기도 감염증상으로 접종 후 7일 이내에 639명 중 16명(2.5%)에서 보고되었다. 1명에서 grade 3 이상의 장염증상을 보고하였으며, 11명(1.7%)에서 중대한 이상반응을 보고하였으나, 이들은 모두 연구 종료 이전에 호전되었다. 결론: 6년 동안의 시판 후 조사에서, 건강한 우리나라 영아들을 대상으로 한 주사용 소아마비 사백신(Poliorix$^{TM}$) 접종은 국내 건강한 소아에서 안전하고 내약성이 충분하였다. Objective: As per the requirement of Korean Food and Drug Administration, this post-marketing surveillance was conducted in Korea to evaluate the safety and reactogenicity of Poliorix$^{TM}$ following its introduction in 2006. Methods: In this open, multicenter study, the vaccine was administered as per the current practice of Korean doctors and in reference to the guidebook by the Korean Pediatric Society and as indicated in the Korean label which was as follows - for primary vaccination three doses were given to infants at ages 2, 4 and 6 months whereas, for the booster dose a single dose was given to children aged 4-6 years. Safety data during this six year surveillance was collected using diary cards which were distributed to the parents to record adverse events. Results: A total of 639 subjects were enrolled into the study. Of these, 617 subjects and 22 subjects received the vaccine as a primary and booster dose, respectively. At least one unsolicited symptom was reported in 11.4% (73/639) of the subjects during the 7-day follow-up period; upper respiratory tract infection (2.5%;16/639) was the most frequently reported unsolicited symptom. One subject reported at least one unsolicited symptom (gastroenteritis) of grade 3 intensity within the 31-day post-vaccination period. Approximately 1.7% (11/639) of subjects reported 13 serious adverse events (SAEs). All SAEs were resolved by the end of the study. Conclusion: In Korea, primary and booster vaccination with Poliorix$^{TM}$ was well-tolerated in healthy subjects when administered according to the prescribing information as part of routine clinical practice.

Postural Instability and Cognitive Dysfunction in Early Parkinson's Disease

Lee, Jong Moon,Koh, Seong-Beom,Chae, Sung Won,Seo, Woo-Keun,Kwon, Do Young,Kim, Ji Hyun,Oh, Kyungmi,Baik, Jong Sam,Park, Kun Woo Cambridge University Press 2012 The Canadian journal of neurological sciences Vol.39 No.4

<B>Background:</B><P>Postural instability is one of the most disabling features of Parkinson's disease, usually occurring in late and advanced stages. The aim of this study was to investigate the postural performance of early-stage de novo Parkinson's disease patients with no clinical postural instability using computerized dynamic posturography. We sought to understand the relationship between postural sway and disease severity and the relationship between postural instability quantitatively measured by computerized dynamic posturography and cognitive impairment in early-stage Parkinson's disease patients.</P><B>Method:</B><P>Thirty-one subjects with Parkinson's disease and 20 healthy controls were assessed by the computerized dynamic posturography protocol using the sensory organization test and the motor control test. A neuropsychological assessment was also administered.</P><B>Results:</B><P>The mean equilibrium score for sensory organization test and the vestibular input ratio were significantly correlated with Hoehn-Yahr stage. No associations between motor latency for any motor control test condition and Hoehn-Yahr stage were found. The equilibrium score for sensory organization test correlated with the mini-mental status examination scores. There was a significant correlation between motor latency for large backward translation and mini-mental status examination scores. There were significant correlations between visual perception/construction/ memory of the neuropsychological battery test and the equilibrium score for sensory organization test and between verbal word learning test, controlled word association test and motor latency for large backward translation.</P><B>Conclusion:</B><P>These findings showed the postural instability present in early-stage (Hoehn-Yahr stage 2-2.5) Parkinson's disease. We also found a close relationship between postural instability and cognitive function in Parkinson's disease patients.</P>

간경변증 환자의 말초혈액단핵구에서 중합효소연쇄반응법을 이용한 Cytomegalovirus DNA 의 검출

문종호(Jong Ho Moon),유창범(Chang Beom Ryu),박철호(Cheol Ho Park),류권호(Kwon Ho Ryu),박찬욱(Chan Wook Park),이준성(Joon Sung Lee),이문성(Moon Sung Lee),조성원(Sung Won Cho),황승덕(Seung Deok Hwang),심찬섭(Chan Sup Shim),이희발(Hi Ba 대한내과학회 1995 대한내과학회지 Vol.49 No.6

N/A Objectives: Human cytomegalovirus(CMV) infections are common and usually asymptomatic, but fatal infections occur frequently in immunocompromised patients. In Korea, CMV infection is common and patients with liver cirrhosis are frequently in a condition of immunosuppression, may predispose to the frequent occurrence of CMV infections. The purpose of this study was to investigate the prevalence of CMV infection in patients with liver cirrhosis and to evaluate the relationship between the status of C3:IV infection and liver function. Methods, The subjects of this study were 36patients with liver cirrhosis, 4patients with non A, non B, non C(NANRNC) hepatitis, and 13normal controls. IgG and IgKI antibodies to CMV were measured using a microparticle enzyme immunoassay(MEIA). Specimens of urine were cultured for CMV using shell vial culture method. Peripheral blood mononuclear cells(PBMC) were investigated for the presence of CMV-DNA using PCR. Rusults: In CMU antibody test, IgM and IgG antibodies were detected in 7(19.4%) of 36patients with liver cirrhosis, IgG antibody was detected in the other 29patients and all control subjects. In shell vial culture, CMV was cultured in 1(2.8%) of 36patients with liver cirrhosis(IgM and IgG positive). CMV DNA was detected by PCR in 19(52.8%) of 36patients with liver cirrhosis, but 1(7.7%) of 13 control subjects (p<0.05). CMV DNA was detected in 6(85.7%) of 7cirrhotic patients with IgM and IgG antibodies positive, 13(44.8%) of 29cirrhotic patients with IgG antibody positive. CMV DNA positive cirrhotic patients show 5(26.3%) in Child A, 6(31.6%) in Child H, 8(42.1%) in Child C. CMV DNA negative cirrhotic patients show 4(23.5%) in Child A, 12(70.6%) in Child B, 1(5.9%) in Child C(p<0.05). CMV DY:A positive cirrhotic patients showed the tendency of more frequent detection of HBsAg and HBeAg than CMU DNA negative cirrhotic patients(p<0.05). Conclusion: These results suggest that CMV infection is common in cirrhotic patients and the CMV DNA positive patients with liver cirrhosis have more impairment of liver function than the CMV DNA negative patients with liver cirrhosis.

원자력 발전소 공기 조화용 HEPA 필터 설계

박종범(Jong Beom Park),권태종(Tae Jong Kwon),문기원(Ki Won Moon),이세엽(Se Yup Lee) 대한전기학회 2000 대한전기학회 학술대회 논문집 Vol.2000 No.7

SNS 만족도가 소셜커머스 신뢰성 및 지속사용에 미치는 영향에 관한 연구

문종범 ( Jong Beom Moon ),김인섭 ( In Sub Kim ),정원준 ( Won Jun Jung ) 한국경영공학회 2012 한국경영공학회지 Vol.17 No.2

SNS based Social commerce is becoming an issue in our economy and is increasing drastically. Even though there is relatively low entry barrier, the Big three social commerce companies account for more than 50% of the total Korean market. It is required to understand and prepare the characteristics of social commerce when start a new business in social commerce area. In addition, consumer complaints are also increasing due to the relatively low level of services in social commerce. Any social commerce company is not able to provide basic services and it shows a loophole such as customer management. There are these problems in the sales-driven social commerce. Players of social commerce marketplace are divided into consumer, supplier, and seller. This study tried to figure out the relationship among SNS satisfaction, Social Commerce Reliability and Continuous Usage. Based on the results of empirical analysis, we suggests business strategy for social commerce companies. The results of this study can be summarized that there are structural relationship among SNS attitudes, SNS satisfaction, reliability, and continuous use of social commerce. Concretely, SNS attitudes influence to SNS satisfaction and the SNS satisfaction influence to reliability and continuous use of social commerce.

Distribution of chitinases and characterization of two chitinolytic enzymes from one-year-old Korean Ginseng (Panax ginseng C.A. Meyer) roots

( Jong Kook Moon ),( Beom Ku Han ),( T. Doohun Kim ),( Do Hyun Jo ) 생화학분자생물학회 (구 한국생화학분자생물학회) 2010 BMB Reports Vol.43 No.11

We report the tissue-specific distribution of chitinolytic activity in Korean ginseng root and characterize two 31-kDa chitinolytic enzymes. These two enzymes (SBF1 and SBF2) were purified 70- and 81-fold with yields of 0.75 and 1.25%, respectively, and exhibited optimal pH and temperature ranges of 5.0-5.5 and 40-50℃. With [3H]-chitin as a substrate, Km and Vmax values of SBF1 were 4.6 mM and 220 mmol/mg-protein/h, respectively, while those of SBF2 were 7.14 mM and 287 mmol/mg-protein/h. The purified enzymes showed markedly less activity with p-nitrophenyl-N-acetylglucosaminide and fluorescent 4-methylumbelliferyl glycosides of D-N-acetylglucosamine oligomers than with [3H]-chitin. End-product inhibition of both enzymes demonstrated that both are endochitinases with different N-acetylglucosaminidase activity. Furthermore, the NH2-terminal sequence of SBF1 showed a high degree of homology with other plant chitinases whereas the NH2-terminal amino acid of SBF2 was blocked. [BMB reports 2010; 43(11): 726-731]

Free Paper Session : Liver 2 ; The Long-Term Safety And Efficacy Of Prophylactic Endoscopic Histoacryl Injection For Gastric Varices With High Risks Of Beeding

( Moon Kyung Joo ),( Jae Seon Kim ),( Kwan Soo Byun ),( Young Tae Bak ),( Jong Jae Park ),( Beom Jae Lee ),( Sehe Dong Lee ),( Yun Jung Chang ),( Young Kul Jung ),( Jung Han Kim ),( Ji Hoon Kim ),( Jo 대한소화기학회 2007 SIDDS Vol.9 No.-

Background/Aims: Gastric varices (GVs) are usually critical when bleeding occurs. Endoscopic histoacryl injection (EHI) is reported to be effective treatment for bleeding GVs and prophylactic EHI might be beneficial in patients with risk factors for a hemorrhage from GV. The aim of this study was to evaluate safety and outcomes of EHI for GVs with high risks of bleeding. Methods: 47 patients (33 males/14 females, mean age 56.6 years old) with gastric varices underwent EHI (35 primary prophylaxis/12 secondary). Large tumorous showed in 35 patients, red color sign 19 and rapidly growing in size in 1. 10 patients had IGV1 type, 28 GOV2, and 9 GOV1, respectively. EHI was performed in a standard method and repeated injection was done as needed within 3 days. Results: Obliteration of GVs was achieved in all of the treated patients. 34 patients required 1 session and 13 patients more than 2 sessions to obliterate GVs. A mean of 2.21mL of histoacryl was used. As a procedure-related complication, oozing on injection site was developed in 3 patients and bacteremia in 2. The mean duration of follow-up was 10.2 months and eradication of GVs was achieved in 24 patients among 26 patients followed up more than 3 months (92.9%, mean duration 5.6 months). 3 patients recurred during endoseopic follow up (12.0% mean duration 1.07 months). Bleeding event occurred in 7 patients (4 patients in index varix, 2 in esophageal varix, 1 in other focus, cumulative bleeding rate was 5.8%, 12.8%, 21.3% at 3, 6, 12 months after EHI, respectively) and 16 patients died after EHI (cumulative mortality rate was 22.2%, 28.2%, 38.7% and 43.4% at 6, 12, 24, 36 months after EHI, respectively). Among 8 patients who died, 2 patients died from GV bleeding, 2 liver failure, 1 renal failure, 2 sepsis, 1 others. Conclusions: Prophylactic EHI for GVs with high risks of bleeding was a feasible, safe and effective procedure for eradication and prevention of recurrence. The overall mortality rat was 43.4% at 3 years after EHI.