하수슬러지를 이용한 복합소재 개발연구

연규석,권윤환,유근우,김남길,김동준,이윤수 강원대학교 부설 석재복합신소재 제품연구센터 2002 석재연 논문집 Vol.7 No.-

본 연구는 하수 종말 처리에 의해 발생되는 하수 슬러지를 잔 골재(경량골재)로 사용하여, 폴리머 콘크리트를 제조하여 그 때의 역학적 성질에 대하여 검토하였다. 하수 슬러지는 5일간 110±5℃에서 수분함량 0.1%미만으로 건조한 후 파쇄하여 No.4∼No. 200 번체의 잔골재 표준 시방서 기준에 부합되도록 사용하였다. Pellet는 보통 회전pan에서 만드나, 본 실험에서는 수동으로 제조하였다. 제조한 하수 슬러지 경량 골재는 평균 겉보기 비중은 1.58(g/㎤), 단위용적중량은 1.98(t/㎥)으로 KS F 2534의 경량골재의 절건비중과 단위용적에 따른 분류에 의하면 중위급(medium weight) 경량골재에 속하는 것으로 측정되었다. 또한 잔 골재 중 하수 슬러지 경량 골재를 0%, 5%, 10%, 15%, 20%, 25%, 30%로 치환하여 그때의 압축, 휨, 인장강도를 측정하였다. 그 결과 하수 슬러지의 증가에 따라 강도 감소를 보였으나, 일반 경량콘크리트 제조 또는 단열용 콘크리트 블록 제조에 사용이 가능하다고 사료된다. 그러므로 앞으로 건조수축, 크리이프 특성 및 내구성에 관한 연구가 더욱 심도 있게 이루어져야 폐자원인 하수 슬러지를 이용한 건자재의 개발이 가능하리라 판단된다. In this study, the polymer concrete was produced by using the lightweight aggregate that had been manufactured using the sewage sludge and its physical properties were experimentally examined. Experimental results show that when the portion of sewage sludge lightweight aggregate in the fine aggregate increases, slump values decreases. Also, the compressive, the flexural and the tensile strengths decrease when the portion of sewage sludge lightweight aggregate increases. Although its strengths decreases, the sewage sludge lightweight fine aggregates is thought to be used for construction materials.

정신분열병 환자의 병식과 임상양상의 관련성에 관한 연구

주연호,김수동,송진우,박성덕,오석배 용인정신의학연구소 1998 용인정신의학보 Vol.5 No.2

美國急進主義運動의 擡頭와 衰退要因硏究

鄭然植,金慶麟,陳壽美,金東根 慶北大學校 1986 論文集 Vol.42 No.-

The purpose of this study is to explore the unfolding of the radical movement in the United States during the turn of this century. It particularly concerns about the factors determining the uprising of the radicalism at the end of the 19th century and its fall with the World War Ⅰ. The rise of American radical movement can be traced back to the industrializing era after the Civil War. It started as a reaction to the evils resulted from the rapid industrialization. Initially several movements broke out sporadically, however, until the radical ideology from Europe was flowed in. Then, the radical movement was accelerated. During this period, the leading figures who particularly influenced the development of the movement were: De Leon from the Socialist Labor Party; Gompers from the American Federation of Labor; Debs from the Socialist Party; and Haywood from the Industrial Workers of the World, etc. The movement in this era was unfolded the following historical phases: from 1870s to 1880s, the preparation stage of organizing the movement; 1890s, early action stage characterized by the Populist Movement, Pullman Strike, etc.; 1900s, the flourishing phase led by the Socialist Party and IWW; the declining phase was followed since the end of 1910s; after 1920s, American pragmatism again prevailed over radicalism. Factors attributed to the rise of the radical movement are: depravation of entrepreneurship; recurrent economic crises; deterioration of labor conditions; the influence of Marxism; and insensitive attitudes on the part of the capitalists and government. This paper also suggests the factors determining the decline of the movement: the rise of the American patriotism around the World War Ⅰ era; government's strong counteractions; anti-socialism prevailed by the negative impact of the Soviet Revolution; collapse of the movement organizations; economic recovery after the War; and the government's implementations of reforming policies. At conclusion, radicalism in the United States has played the preventive role against the risk of irreversible corruption of the Establishment and its rigidity.

신체계측치를 이용한 체지방의 평가 및 이용에 관한 연구

유병연,이영수,이동배 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.1

This study was performed to obtain an estimate of body fat and its distribution assessed by anthropometic measurements in normal (235 cases) and diabetic subjects( 15 1cases).We assessed relative weight,body mass index (BMI),skinfold thickness,body circumference and skinfold and body circumference ratio. Also, assessment of body composition was measured by bioelectrical impedance (Valhalla 1990B). The results were as follows. 1. In normal control group,hip circumference was larger in male than female.All skinfold thickness was larger in female than male,but sexual differences were smaller than those in diabetics. 2. In diabetic subjects,hip circumference and skinfold thickness were larger in women than men. 3. In spite of the distinct changes of fat distribution observed in normal and diabetic subjects,there was no significant changes in the total body fat content. However,more body muscle mass(%) was observed in normal control than diabetic subjects. 4. In male group with normal ideal body weight,the circumferences of the arm,hip and thigh were significantly larger in control group than diabetics.But in female group,waist circumferences were larger in diabetics than control subjects. 5. The thigh and calf skinfold thickness were thicker in control subjects,but the subscapular skinfold thickness were thicker in diabetics particularly in female. 6.In female groups,waist-to-hip circumference ratio (WHR),waist-to-th igh circumference ratio(WTR) and waist-to-calf circumference ratio(WCR) were significantly larger in diabetics than control group. 7. In diabetic female patients,there were more central body fat,represented by subscapular-to-triceps skinfold ratio(STR) and central peripheral skinfold thickness ratio(CPR),than control group(female).8. In female,there was a significant correlation between triglyceride and waist-to-hip circumference ratio(WHR),subscapular-to-triceps skinfold ratio(STR) and,in male,the abdominal skinfold thickness. 9. There was more positive correlation between the anthropometric parameters and percentage of body fat in diabetics. This study suggests that combination of various anthropometric measurements could be used as an indicator in determining the amount and effect of exercise and other remedies in diabetic patients.

고추 역병 저항성 재료의 특성평가와 종자 증식

김동우,김병수,배수연,한정혜 慶北大學校農業科學技術硏究所 2002 慶北大農學誌 Vol.20 No.-

역병 저항성 재료로 도입하여 유지하고 있는 PI123469, PI201234, PI201232, AC2258 (=Line 29), CM334, KC268, KC358, KC820, KC821, KC822, KC823 (Line 29 = AC2258), KC462, KC463, KC464 혹은 이들 유전자원에서 선발한 계통들의 역병에 대한 저항성 검정, 원예적 특성 조사 및 종자 증식을 실시하였다. PI123469, PI201234, PI201232, AC2258, KC823 에서 선발된 계통들이 가장 저항성이 강한 것으로 나타났다. 동일한 유전자원에서 선발한 계통간에도 저항성 수준에서 현저한 차이가 관찰되는 경우가 있었으며, 이러한 경우는 주로 유지 증식과정에 자연교잡이 일어난 결과로 추정되었다. 따라서 순도 높은 저항성 재료를 얻기 위해서는 봉지를 씌워 자식종자를 채종하는 것이 가장 안전하며, 다음으로는 계통 망실 혹은 망상을 이용하는 것이 바람직한 것으로 판단되었다. Resistance to Phytophthora capsici and horticultural characteristics of selections from the resistance sources such as PI123469, PI201234, PI201232, AC2258 (=Line 29), CM334, KC268, KC358, KC820, KC821, KC822, KC823 (Line 29), KC462, KC463, KC464 were evaluated and recorded in the process of seed increase. Selections of PI123469, PI201234, PI201232, AC2258, KC823 (Line 29 = AC2258) of them showed the highest level of resistance. A considerable difference in the level of resistance was observed between lines selected from the same sources. The variation between selections derived from the same source was thought to ve attributable to natural cross-pollination that may have occurred during the seed increase. Therefore, securing self-pollinated seed by wrapping the flower buds before anthesis would be necessary to obtain genetivally pure resistant lines. The next alternative would be to increase the seed in small net houses for single line or field cage.

주의력결핍/과잉행동장애와 양극성장애 공존 환아군과 주의력결핍/과잉행동장애 환아군의 비교연구

정동선,하규섭,정희연,구훈정,황준원,김붕년,신민섭,조수철,홍강의 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.6

Objective : Attention deficit hyperactivity disorder (ADHD) is frequently comorbid with a variety of psychiatric disorders. Among them, bipolar disorder (BPD) has especially attracted growing interest. This is partly due to the fact that early onset BPD has been frequently misdiagnosed as ADHD because of symptomatic overlap. The aim of the present study is to find the differences in demographic data and clinical features of ADHD+BPD and ADHD in children and adolescents. Method : Children and adolescents patients participating in the present study have been enrolled at the child psychiatric clinic since 2004. 14 patients meeting the DSM-IV chteria for ADHD+BPD and 19 patients meeting the criteria for ADHD and 15 healthy comparison subjects were recruited. All groups were evaluated through the Schedule for Affective disorders and Schizophrenia for School-Age Children-Present and Life Time version-Korean version (K-SADS-PL-K). Demographic data and clinical charactehstics of the subjects were also collected. Parents were asked to complete the Child Behavior Check List(CBCL) and the Toddler Temperamental Scale (TTS) clinical ratings were obtained using the Young Mania Rating Scale(YMRS), the Children's Depression Iventory (CDI) and the Dupaul ADHD scale. Clinical variables between ADHD+BPD and ADHD were analyzed using the Mann-Whitney U test. YMRS, CDI, Dupaul ADHD scale (inattention and hyperactivity), CBCL, and TTS among the three groups were analyzed using the Kruskal-Wallis test with post-hoc Mann-Whitney U test. Results : 1) ADHD+BPD group had an earlier onset age of ADHD than ADHD group 2) ADHD+BPD group had more co-morbid psychiathc disorders than ADHD group. 3) Compared to ADHD group, ADHD+BPD had more psychiathc family history, especially mood disorders. 4) ADHD+BPD group had prodromal symptoms such as irritability, anger dyscontrol and academic dysfunction, compared to ADHD group who rarely showed prodromal symptoms. 5) ADHD+BPD group had higher ADHD scores than the ADHD group in the Dupaul ADHD inattentive scale. 6) In global functions of CBCL, ADHD+BPD group showed more impaired functions at home and school than ADHD group. 7) In Attention diagnostic system (ADS), ADHD+BPD group had more omission and commission errors than ADHD group, especially in the visual system. 8) In the subtests of the IQ profile, ADHD+BPD group had lower arithmetic and block design scores than ADHD group. Conclusion : Clinicians have to rule out underlying bipolarity in children and adolescents with ADHD who show earlier age of onset and severe clinical features. Bipolarity should be explored intensively in ADHD children and adolescents who have early onset of symptoms and severe functional impairment.

초기계태에서 valproic acid에 의한 신경관 기형 : 입체현미경적 관찰

김동호,조무연,정유남,최영주,이종선,민경수,이무섭 충북대학교 의학연구소 2000 忠北醫大學術誌 Vol.10 No.1

연구목적 ' 항경련제인 valproic acid가 초기계태의 신경관 형성에 영향을 주는 기형유발에 대해 입체현미경하에서 관찰하였다 연구재 료 및 방법 : 백색의 Leghorn의 신선한 수정란을 30-35시간 동안 배양하여 Hamburger & Hamilton 기 5-10기의 초기 계태를 천공 필터를 이용하여 분리하여 6-30시간 동안 CO2 세포 배양기에서 배양하였고 무작위로 대조군과 실험군을 분류하였다. 실험군은 valproic acid 의 RPMI culture media 의 농도에 따라 100 ㎍/㎖, 200 ㎍/㎖, 500 ㎍/㎖, 1000 ㎍/㎖ 네가지 군으로 분리하였다. 각각의 대조군과 valproic acid를 처치한 실험군에서 입체 현미경하에서 초기계태의 신경관 형성의 형태학적인 특징과 기형형성의 빈도를 비교하였다. 결과: valproic acid가 없는 RPMI media에서 배양된 대조군은 24개의 계태는 22(91.7%)개는 정상으로 자랐으며 2(8.3%)개는 비정상으로 자랐다 이에 반하여 valproic acid가 처치된 RPMI media에서 배양된 72개의 계태는 42(58.3%)개가 비정상으로 자랐다. 주로 확인된 이상 형태는 신경주름의 변형. 신경관 폐쇄부전, 체절의 장애 및 발육 정지 등 이었다. 계태의 기형 형성은 valproic acid의 농도에 비례하여 증가하였다. valproic acrid 의 농도가 100 ㎍/㎖인 경우 18개 계태 중 2(11.1%)개에서 경미한 신경관 기형이 나타났으며 200 ㎍/㎖인 경우 18개 계태 중 11(61,1%)개는 정상, 7(38.9%)개는 명백한 신경관 기형이 나타났으며 500 ㎍/㎖인 경우 18개의 계태 중 5(27.8%)개는 정상. 13(72.2%)개는 명백한 신경관 기형을 나타냈다. 1000 ㎍/㎖인 경우 18(100%)개 모두 심한 신경관 기형이 나타났다. 결론: valproic acid는 초기계태에서 신경관 기형을 유발 했는데 저농도에서는 일부 경미한 신경관 이상을 보였고 고농도에서는 대부분 심한 신경관 손상을 동반하고 성장 속도가 둔화되어 약 용량의 증가에 따라 기형이 증가되는 dose-dependent manner 로 그 영향이 나타났다. Purpose : The teratogeruc effects of valproic acid widely used as anticonvulsant on the neurulation of the explanted eraly chick embryos were observed by the stereoscope. Materials and Methods: Fresh fertilized white leghorn hen eggs were incubated for 30-35 hours in an e99 incubator. The Hamburger and Hamilton stage 5-10 chick embryos were explanted using the punched-out filter paper explantation technique and cultured in the CO2 cell culture incubator for 6-30 hours. They were randomly divided into a control group and an experimental group. The experimental group was divided into four subgroups according to the valproic acid concentrations of 100 ㎍/㎖, 200 ㎍/㎖, 500 ㎍/㎖, 1000 ㎍/㎖ with which the RPMI culture media were treated. The morphological characteristics and the incidences of teratogenic effects on the neurulation of early chick embryos in the control and experimental groups were compared with each other using the stereomicroscope. Results : Of the 24 chick embryos cultured in the RPMI media without valproic acrid, 22 embryos(91.7%) developed normally, and 2 embryos (8.3%) developed abnormally, in contrast, among 72 embryos cultured in the valproic acrid-treated media, 42 embryos(58.3%) developed abnormally. The frequent anomalous features were deformities of the neural folds, failure of neural tube closure, derangement of somites, and developmental arrest. Of 18 embryos cultured in the media treated each with 100㎍/㎖ of valproic acid, 2 embryos(11.1%) showed mild abnormality of neural tube defect on stereoscopic examination. Of 18 embryos cultured 7l the media treated each with 200㎍/㎖ of valproic acid, 11 embryos(61.1%) developed normally for 20 hours and 7 embryos (38.9%) showed definite neural tube defect. Of 18 embryos cultured in the media 7reated each with 500㎍/㎖ of vaIprolc acid, 5 embryos(27.8%) developed normally (or 20 hours and 13 embryos (72.2% ) showed definite neural tube defect. Of 18 embryos cultured in the media treated each with 1000㎍/㎖ of valproic acid, 1 embryo developed normally for 4 hours but all embryos (100%) showed severe neural tube defect on whole brain after 8 hours of culture. Conclusion : Valproic acid induced mild neural tube defects in low concentration and in high concentration of valproic acid, most chick embryos developed slowly and showed severe neral tube defects. The frequency and severity of abnormal embryos ulcreased in dose-dependent manner.

B형 간염 동반 원발성 간암 환자에서의 CYP2D6와 NAT2 다형현상에 관한 연구

신동일,이광수,최연남,황기은,조율희 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.2

The CYP2D6 and N-acetyltransferase (NAT2) are polymorphic enzymes which are expressed in the hepatocyte in a genotype-determined manner. CYP2D6 and NAT2 are known to be involved in the inactivation and activation of various mutagens and carcinogens, respectively. The activities of the two enzyme systems are associated with the genetic susceptibility of many human cancers. This study was performed to determine the genotype frequencies of the two enzyme systems in primary hepatocellular carcinoma patients and healthy controls. One hundred healthy controls and 55 liver cancer patients were analyzed by polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP). The results are as followings:1. In the healthy controls, CYP2D6 wild type allele frequency was 0.985 and CYP2D6^*4 frequency was 0.015, and no CYP2D6 poor-metabolizer was detected. No significant differences were found in hepatocellular carcinoma patient group. 2. Frequencies of F, S1, S2 and S3 alleles of NAT2 system were 0.725, 0.01, 0.14 and 0.125 in controls, respectively. The genotype frequencies were found to be 0.91 of rapid acetylator and 0.09 of slow acetylator. No significant differences were found in hepatocellular carcinoma patient group. 3. These results suggest that the distribution of CYP2D6 and NAT2 polymorphisms is very unique in Korean populations characterized by extremely low frequency of CYP2D6 poor-metabolizer and NAT2 slow acetylator. CYP2D6 and NAT2 polymorphisms seemed not to play an important role in the hepatic carcinogenesis in Korean population.

휨이 지배하는 건축 합성지하벽의 非線型 擧動에 관한 硏究

徐洙演,崔生吉,辛同寅 충주대 2003 産業科學論文集 Vol.11 No.-

In the design of retaining wall, generally, H-PILE is used to be considered as not structural member but temporary one. However, if the H-PILE has structural resistance for horizontal earth pressure, the structural capacity of retaining wall system can be enhanced. Especially, the contribution of H-PILE to the structural resistance is to be maximized when it behavior as a composite member with retaining wall. In this paper, an analytical study is presented for Composite Basement Wall(CBW) combined H-PILE and retaining wall by shear connector. previous test results for CBW are summarized and the flexural behavior of the composite wall is estimated by the non-linear finite element program, ATENA. In the modeling of shear connectors which connect steel beam and concrete wall, simple interface element is used. From the analytical result, it is shown that the flexural behavior of CBW can be predicted by using ATENA.

일부 한국인의 혈청 ceruloplasmin 정상 참고치 설정 및 질환별 비교 : Comparison of Its Level among Various Diseases

이동수,박애자,박정덕,장임원,홍연표 중앙대학교 의과대학 의과학연구소 1999 中央醫大誌 Vol.24 No.1

Ceruloplasmin has been investigated as one of the useful biologic index for early diagnosis of atherolsclerosis. However, there was no normal reference value taking into account the confounders in Korea. This study was performed to estimate the normal reference values and present the confounders of ceruloplasmin. Also we compared of serum ceruloplasmin levels among normal reference group and three abnormal groups: 475 healthy subjects, 53 liver dysfunctions, 72 positive test of chronic inflammatory diseases, and 89 hypercholesterolemias. Mean serum ceruloplasmin level of healthy subjects were 41.6±7.6㎎/㎗ in males and 42.1±7.2㎎/㎗ in females, respectively. It was tend to increase of ceruloplasmin by age in both sexes. However, the statistical difference was not found by age group between both sexes. Statistically significant correlations were found between serum ceruloplasmin and age, body mass index(BMI), white blood cell(WBC) and triglyceride(TG) in males and age, BMI, WBC and total cholestrol(TG) in females. After adjustment for age, BMI,WBC and TG in males and age, BMI, WBC and TG in females, significant elevations of serum ceruloplasmin were found in liver dysfunction(p=0.0077) and positive test of chonic inflammatory disease(p=0.0217) in males and in oisitive test of chronic inflammatory disease(p=0.0023) and hypercholestolemia(p=0.0124) in females relative to healthy reference subjects. There is no statistical difference among liver dysfunction, postive test of chronic inflammatory disease, and hypercholesterolemia.