업무상질병 발생 근로자의 특성 : 1999년 업무상질병으로 요양승인된 사례분석

안연순,강성규,권현길,정호근 大韓産業醫學會 2001 대한직업환경의학회지 Vol.13 No.4

목적 : 이 연구는 1999년 근로복지공단에서 업무상질병으로 인정한 사례를 정밀분석하여 직업병의 종류와 특성을 밝힘으로써 직업병 예방사업이나 산업보건연구의 우선순위를 결정하는데 기초자료로 제공하기 위하여 실시하였다. 방법 : 근로복지공단 주전산망을 통하여 재해일자가 1999년 1월 1일부터 12월 31일까지인 근로자 중2000년 6월 30일까지 요양이 승인된 업무상 질병자2,333명을 파악하고 이 중 뇌심혈관계질환자 1,348명과 근골격계질환자 410명을 제외한 575명을 연구대상으로 하였다. 소속 사업장 또는 연구대상 근로자에 대하여 우편 또는 전화 면담조사를 실시하여 업무상 질병자의 성, 연령, 질병 관련 작업기간, 질병 인지경위, 업종, 직종, 질병종류, 사업장규모 등에 대한 조사를 실시 후 기술분석을 시행하였다. 결과 : 업무상 질병자 575명 중 남성이 511명(88.9%), 여성이 64명 (11.1%)이었다. 사망유무는 조사당시에 사망자가 56명(9.7%)이었고, 사망하지 않은 자가 519명 (90.3%)이었다. 연령별로는50~59세가 217명(37.7%)으로 가장 많았고, 질병관련 근무기간은 10년 이상 근무자의 비율이 49.0%로 가장 높았다. 질병인지경위는 소음성 난청, 진폐증, 이황화탄소 중독으로 인한 업무상 질병자를 제외하고 건강진단을 통하여 질병을 발견한 경우가 조 사자의 12.7%fl 불과하였다. 소속 사업장 규모는5인 미만 사업장이 26.1%로 1999년 당시 산재보험 임의가입 대상인 5인 미만 사업장에 소속된 근로자의 비율이 가장 높았다.질병별로는 호흡기질환이 211명(36.7%)으로 가장 많았고, 다음으로 소음성 난청(이명 1명 포함)149명 (25.9%), 감염성질환 69명(12.0%), 유기용제, 중금속, 가스 등에 의한 중독성질환 60명(10.4%) 순이었다. 기타 피부질환 29명, 암 17명,양성종양(성대결절) 8명, 간장질환 9명, 일사병 및열사병 6명, 신경정신질환 5명, 신경계질환 4명, 안질환 3명, 혈액 ·골수질환 2명, 신장질환 1명, 기타2명이었다. 유해인자별로 분류하였을 때, 분진 209건(36.3%), 물리적인자 157건(27.3%), 화학적인자 89건(16.3%), 생물학적인자 82건(14.3%),작업판련성인자 34건(5.9%), 분류불능 4건으로 분진에 의한 업무상질병의 비율이 가장 높았다.종사업종은 제조업이 262명(45.6%)으로 가장 많았고 다음으로 광업 174명(30.3%), 기타 각종 행정기관 일용직 종사업이 42명 (7.3%), 의료업이 28명 (4.9%)이었다. 직종별로는 기능원 및 관련기능종사자가 285명 (49.6%)으로 가장 많았고 다음으로 장치, 기계조작 및 조립종사자 139명 (24.2%), 단순노무종사자 72명 (12.5%), 전문가 28명 (4.9%), 사무종사자 IS명(2.6%), 기술공 및 준전문가14명(2.4%), 행정 및 경영관리자 8명(1.4%), 판매 및 서비스종사자 8명(1.4%), 미상 6명이었다. 결론 : 이 연구를 통하여 우리나라에서 업무상질병으로 인정받고 있는 사례들을 분석함으로써 기존 통계에서 알 수 없었던 내용을 전체적으로 파악할 수있었고, 인첫받는 사례의 상당부분이 산업의학적 관리의 주요 대상인 팡업이나 제조업 이외의 업종에서 발생하고, 근무조건이 열악한 일용직 근로자에서 발생한다는 사실을 파악하였다. 또, 소음성 난청과 진폐증을 제외하고 업무상질병 승인자의 약 90% 가산업안전보건법상의 건강진단을 통하여 질병을 발견하기보다는 개인적인 병원방문을 통하여 발견한다는 사실을 확인하였다 이것은 작업병을 발견하기 위한특수건강진단 목적중 하나가 제대로 기능을 할 수 없다는 사실을 입증한 것으로 특수건강진단제도이 대한대상자 확대, 검사 항목 확대 등 제도보완이 필요함을 시사하는 결과로 판단된다. 또, 병원근로자, 일용직 근로자 등 업무상질병 위험직종에 대한 업무상질병 예방대책도 조속히 수립되어야 할 것이다. Objectives : The purpose of this study is to analyze the characteristics of occupational diseases listed by Korea Labor Welfare Corporation (KLWC). Methods : Using the database of the KLWC, we collected 575 approved occupational disease cases occurring between 1 January and 31 December 1999 and approved by the thirtieth June in 2000. We investigated the characteristics (sex, age, occupational history, kinds of occupational disease, exposure material, type of enterprises, etc.) of occupational disease using a mail survey and telephone interviews. Results : Men accounted for 88.9 %(511 workers) of the approved cases. 56 cases(9.7 %) died of occupational disease. The most common age group was 50∼59 years of age(n=217, 37.7 %). The proportion of workers with grater than ten years disease related working condition exposure were 195 (49.0 %). The majority of diseases were respiratory problems(211 workers, 22.4%), occupational healing loss(149 workers, 25.9%), infectious disease(69 workers, 12.0%), intoxication(60 workers, 10.4%), skin disease(29 workers, 5.0%) and cancer(17 workers, 3.0%). The causal hazardous agents were dusts(209 cases, 36.3%), physical agents(157 cases, 27.3 %), chemical agents(89 cases, 16.3 %), biological agents(82 cases, 14.3 %) and work-related agents (34 cases, 5.9 %). The major types of enterprise were manufacturing(262 workers, 45.6 %), mining and quarrying(174 workers, 30.3 %), public administration(42 workers, 7.3 %) and the health care Industry(28 workers, 4.9 %). The kinds of job included craft and related trades workers(285 workers, 49.6 %), plant or machine operators and assemblers(139 workers, 24.2 %), elementary occupations(72 workers, 12.5 %) and professionals(28 workers, 4.9 %). Conclusions : We were able to elucidate the kinds of occupational disease and the characteristics of workers through this study. Many approved cases occurred among non-manufacturing and non-mining workers and the kinds of disease were varied. This suggests that management policy must be established to prevent occupational disease occurring among workers in the above type of industries.

沙上地域 産業體 勞動者의 職場體育 參與擴大 方案

安永弼,鄭琮勳,鄭三鉉,金海禮,趙在基,朴俊東,金垠利,張禎允,金福善,孔庚鎬 東亞大學校附設스포츠科學硏究所 1989 스포츠科學硏究論文集 Vol.7 No.-

파킨슨씨병 환자에 있어서 자가부신수질 이식술

정상섭,박상근,오성훈,김선호,윤도흠,박정수,양우익,최인준,안영수,김경환,박창일,김진수,이현철 대한신경외과학회 1988 Journal of Korean neurosurgical society Vol.17 No.6

Recent experimental studies and clinical cases have suggested that grafting tissue from the adrenal medulla into the brain may alleviate the symptoms of Parkinson's disease. Autologous adrenal medullary grafts into the striatum was performed stereotactically in two patients with Parkinson's disease. Both patients were bedridden preoperatively, but 4 months after the surgery both became ambulatory and one was even capable of returning to his job. Even though the number of cases was small⑵ and the follow-up period was short, this study shows that adrenal medullary transplantation into the striatum may have some beneficial effects in patient with Parkinson's disease. Further experimental and clinical trials are necessary to see whether this procedure will be a recommendable surgical treatment for patients suffering from Parkinson's disease.

부산지역 미술시장의 활성화방안 연구 : 부산의 전시 공간 사(史)와 화랑경영을 중심으로

김청정,안원현,이영준 신라대학교 예술연구소 2000 예술연구 Vol.5 No.-

말단 비대증의 임상적 특성

박은미,안용환,김현정,김병수,임종주,김하영,박병현,조정구 圓光大學校 醫科學硏究所 2004 圓光醫科學 Vol.19 No.2

D 재건축 아파트 소음영향 평가에 관한 연구

정인영,안현태,정유근 慶熙大學校 大學院 1998 高凰論集 Vol.22 No.-

Planning site of redevelopment apartment designed from construction company requires noise environment assessment in the aparment site by adjoining traffic load. Therefore, this study, firstly, measured noise level of the nearest point of apartment in the horizontal distance from the crowded north and south road to measure the noise level of road by environmental influence assessment procedure. After that, through the field measurement, this research aims to measure the noise level within the design site of apartment and assess the noise prevention facility according to the principles of regulation about the housing.

사과 쓰가루의 과대지가 과일의 특성에 미치는 영양

오수옥,이상현,조정안,김영,김월수 全南大學校 農業科學技術硏究所 2001 農業科學技術硏究 Vol.36 No.-

This study was conducted to investigate the effect of bourse shoots on the fruit growth and development, mineral content and quality of apples. Three hundred bourse shoots bearing fruits were selected from 10 trees randomly in the experimental orchard of Chonnam National University, Naju, Southwestern Korea. Bourse shoot length and fruit diameter were measured at twice on July 20 and August 20 of 2001. Harvested fruits were divided into 6 groups according to bourse shoot length; 0㎝, 11 to 20㎝, 21 to 30㎝, 31 to 40㎝, and longer than 41㎝. Fruit characteristics such as (soluble solid content, flesh firmness and acidity) were measures just after the harvest. The contents of Ca, Mg and K were analyzed of fruit peel, flesh and core tissues. Most bourse shoots stopped growing after late June, while water-sprouting shoots stopped after late July. Results showed that fruit L/D ratio was higher when bourse shoots were 31 to 40㎝ in length. Especially soluble solid content and fruit firmness were higher in the fruits of bourse shoot 21 to 30㎝ in length. Calcium contents of the fruits also were higher in flesh and skin tissues when length of bourse shoots was 21 to 30㎝, while no significant differences were observed in other mineral contents.

BTA드릴에 의한 심공가공시 최적절삭조건과 공구수명에 관한 연구

장성규,이충일,전언찬,안찬우,김현수 동아대학교 공과대학부설 생산기술연구소 1996 生産技術硏究所硏究論文集 Vol.1 No.2

The BTA deep hole machining has an increasing because of its wide range applications and its good productivity. The BTA tools are capable fo machining for having a large length to diameter ratio in single pass. It's really necessary that the research for machining of the deep hole drilling by the BTA drilling because its required quality should be satisfied with one time machining. In machining deep holes by single edge BTA drill, P10 class of tool material out of single tube BTA drilling system, we got the result of our study of selecting the optimum cutting condition and tool life for an object, SM55C through our testing as follows. (1) Cutting speed V=42m/min, and feed speed F=90mm/min is the optimum cutting condition and the tool life was about 10 meters. (2) The testing was shown surface roughness was 12㎛, and the roundness was less 16㎛.

토당귀 종자의 형태적 특성과 발아와 입모율에 대한 저장방법,생장조절제 및 프라이밍 처리 효과

안희정,안복주,·김도현,·안영섭,·김영국,박춘근,이상원,·박충범·차선우,·송범헌, 忠北大學校 農業科學硏究所 2015 農業科學硏究 Vol.31 No.1

This study was conducted to have basic and applied informations to establish the cultivation method and to improve the cultivation techniques of Angelica gigas Nakai through investigating the rates of germination and seedling establishment with treatment of plant growth regulator and seed priming. The germination rates of round shape seed were about 0.3~12% higher than those of parallel shape. The germination rates with different storage durations were increased at the level of 25oC and 4oC with the storage days, while they were clearly higher at -20oC compared to those at 4oC and 25oC without the storage durations. With the results of germination rates with treating of plant growth regulator and seed priming, their rates with the round shape seeds were comparatively higher about 6% than those with parallel shape seed and they were increased with increasing of the storage durations. The germination rates were generally appeared higher with GA3 than did those with seed priming. The highest germination rate was appeared at 50 ppm GA3 of plant growth regulator and at -0.5 MPa PEG6000 of seed priming. The germination rates?ㅤ ?ㅤ of Angelica gigas were different with different temperature, storage durations and the treatments of plant growth regulator and seed priming. These results could be used according to different cultivating conditions.

당뇨병 환자에서 혈장 Thrombin-Antithrombin Ⅲ 및 Plasmin-α_2-Plasmin Inhibitor 복합체의 임상적 의의

김경욱,김은숙,정상수,윤수지,박우일,이준희,남수연,안철우,문병수,김경래,차봉수,송영득,임승길,이현철,허갑범 대한당뇨병학회 2002 Diabetes and Metabolism Journal Vol.25 No.5

연구배경:당뇨병 환자에서 혈액응고 및 섬유소용해 체계의 이상경향이 있어 그 결과로 여러 혈관합병증의 발생위험이 높다는 사실은 널리 알려져 있다. 그 기전은 아직 확실히 밝혀지지 않았으나, 고혈당으로 인한 혈장 단백질들의 비효소성 당화작용이나 산화성 스트레스로 인한 유리 라티칼 작용으로 응고항진이나 섬유소용해 활성의 저하를 유발하는 것으로 생각되고 있다. 최근 응고 및 용해인자와 그 억제자의 복합체들의 증가가 이 상태를 비교적 예민하게 반영한다고 알려져 있다. 방법:본 연구에서는 당뇨병 환자 101명과 정상 대조군 20명에서 혈장내 thrombin­antithrombin complex(TAT)와 plasmin­α₂­plasmin inhibitor complex(PIC)를 측정하여 비교하고, 당뇨병 환자에서 미세혈관 합병증과 대혈관합병증의 유무에 따른 차이와, 이미 혈관 질환의 위험인자로 알려져 있는 인자들간의 상관성을 알아보고자 하였다. 결과:1. 환자의 분포를 살펴보면 혈관합병증이 있는 군은 85명, 혈관합병증이 없는 군은 16명이었고, 평균연령은 각각 57.9±14.1세, 49.9±16.6세로 혈관 합병증이 있는 군에서 더 나이가 많았고, 체질량지수는 23.2±3.4㎏/㎡, 24.1±3.4㎏/㎡로 두 군간 유의한 차이는 없었다. 또 두 군간의 혈압 및 HbA1c, 공복혈당 및 인슐린과 C­peptide, 총 콜레스테롤, 중성지방, HDL­콜레스테롤, Lp⒜는 유의한 차이가 없었고, 미세혈관합병증이 있는 군에서 당뇨병의 유병기간이 길었다. 2. TAT 및 PIC의 농도는 정상 대조군에서는 2.8±1.2 ng/mL, 240.4±69.7 ng/mL이었고, 당뇨병 환자군에서는 9.5±22.6 ng/mL, 472.2±258.7 ng/mL이었다. TAT와 PIC 모두 당뇨병 환자군에서 정상 대조군에 비해 유의하게 증가되어 있었고(p<0.001), TAT/PIC ratio는 두 군간 차이가 없었다. 3. 당뇨병 환자의 혈관합병증에 따른 TAT 및 PIC, fibrinogen 농도는 합병증이 없는 군은 각각 4.1±2.4ng/mL, 362.2±272.0ng/mL, 322.7±102.4mg/mL으로 PIC와 fibrinogen의 증가를 보였으나, 연령을 보정한 후에는 통계학적 유의성은 없었다. 또 대혈관 합병증군에서는 각각 6.0±4.9 ng/mL, 507.4±321.6 ng/mL, 427.1±194.7 mg/dL이었으며 미세·대혈관 합병증군에서는 10.4±6.4 ng/mL, 484.8±269.7 ng/mL, 388.4±132.4 mg/dL으로 TAT의 증가를 보였으나 역시 연령을 보정한 후에는 통계학적 유의성은 없었다. 4. 미세혈관합병증군에서 HbA1c(>8%)가 높은 군의 PIC 농도가 유의하게 높았고(p=0.049), 대혈관합병증군에서 HbA1c(>8%)가 높은 군의 총 콜레스테롤 농도가 유의하게 높았다(p=0.042). 5. 총 당뇨병 환자군에서 PIC는 fibrinogen과 HbA1c와 양의 상관관계를, BMI와 음의 상관관계를 보였으며(r=0.47, 0.31,-0.25), 혈관 합병증이 없는 당뇨병 환자군에서만 TAT는 HbA1c와 양의 상관관계를 보였다(r=0.67). 결론:이상의 결과에서 혈장 TAT 및 PIC 농도는 당뇨병 환자에서 정상 대조군에 비해 의미있게 증가되어 있었고, 당뇨병 환자군에서는 연령의 증가와 유병기간이 혈액응고항진 및 용해의 장애에 큰 역할을 함을 알 수 있었으며, 총 당뇨병 환자군에 PIC와 HbA1c와 양의 상관관계를, BMI와 음의 상관관계를 보였으며 혈관 합병증이 없는 당뇨병 환자군에서만 TAT는 HbA1c와 양의 상관관계를 보였다. 따라서 당뇨병 환자에서 혈액응고 및 용해의 장애가 동반되어 있다고 볼 수 있으며, 혈장 TAT 및 PIC는 혈관합병증으로의 진행을 예측하는 지표로서 유용하리라 생각된다. 또 혈당조절정도와 상관성이 있으므로 혈당조절후에 추적검사를 시행하여 합병증의 예방이 가능한지 추후 연구가 필요하리라 생각된다. Background : Abnormality of coagulation and fibrinolystic system is known as a predisposing factor of vascular complication in diabetes. Although the pathogenesis is not well known, non-enzymatic glycation reaction and the increase in production of free radicals due to an increased oxidative stress may be linked to the hypercoagulibility and hypofibrinolytic activity. As indices of abnormality in coagulation and firinolysis in peripheral blood, plasma thrombin-antithrombin Ⅲ complex (TAT) and plasmin-α_2-plasmin inhibitor complex (PIC) were measured. The purpose of this study was to clarify whether hypercoagulability exists in diabetic patients with or without vascular complication. Methods : In our study, we measured plasma thrombin-antithrombin Ⅲ compelx (TAT) and plasmin-α_2-plasmin inhibit or complex (PIC) in 101 diabetic subjects and 20 controls. Comparing TAT and PIC levels in diabetic microvascular complication group, diabetic macrovascular complication group and controls, we examined correlation between risk factors associated with diabetic vascular complication. Results : 1. The group with diabetic vascular complication was older than group without complication. There was no significant difference in BMI, blood pressure, HbA_ic, blood sugar level, insulin, C-peptide, serum creatinine, total cholesterol, triglyceride, HDL-cholesterol, Lp (a) between two groups. The group with diabetic microvascular complication had longer duration of diabetes. 2. Concentration of TAT and PIC were 2.8±1.2 ng/ mL, 240.4±69.7 ng/ mL in controls and 9.5±22.6 ng/ mL, 472.2±258.7 ng/ mL in diabetic patients, respectively. TAT and PIC were significantly higher in diabetic patients than in control (p<0.001). But TAT/PIC ratio was no significant difference between two groups. 3. In diabetic patients, concentration of TAT and PIC and fibrinogen were respectively 4.1±2.4 ng/ mL, 362.2±272.0 ng/ mL, 322.7±102.4 mg/ dL in group without vascular complication and 5.3±4.1 ng/ mL, 529.5±258.7 ng/ mL, 374.9±106.2 mg/ dL in group with microvascular complication, which group had increase in PIC and Fibrinogen but no significance after correction of age. Concentration of TAT and PIC and Fibrinogen were 60.±4.9 ng/ mL, 507.4±321.6 ng/ mL, 427.1±194.7 mg/ dL in macrovascular complication, and 10.4±6.7 mg/ mL, 484.8±269.7 ng/ mL, 388.4±132.4 mg/ dL in combined vascular complication which group showed increase of TAT but also had no significant increase after correction of age. 4. In diabetic microvascular complication patients, group of high HbA_1c (>8%) (p=0.049) had significant high PIC concentration. In diabetic macrovascular complication patients, group of high HbA_1c (>8%) (p=0.042) had significant high total cholesterol concentration. 5. In all diabetic patients, PIC was positively correlated with fibrinogen and HbA_1c and negatively correlated BMI (r=0.47, 0.31, -0.25). Only in daibetic patients without angiopathy, TAT was positively correlated with HbA_1c (r=0.67). Conclusion : In this study, plasma TAT and PIC concentration significantly increased in diabetic patients compared with controls, and PIC was increased in group with microvascular complication, TAT were increased in group with combined micro macrovascular complication. However, there was no significance relationship existed when correctinf for age. PIC was correlated with HbA_1c. TAT was correlated with HbA_1c only in the group without angiopathy. Abnormality of coagulation and fibrinolysis were combined in diabetes, plasma TAT and PIC can be used as an index of vascular complication. Also we found the correlation with the degree of the blood glucose control. Therefore we need follow up study for the possibility of prevention of vascular complication after controlling the blood glucose to age-matched patients (J Kor Diaabetes Asso 25:354~363, 2001).