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RISS 인기검색어
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- 저자 : 이숭구(Sung Ku Lee) (검색결과 6 건)
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활동성폐결핵 환자의 치료에 따른 67Gallium 폐주사의 음전시기의 의의 ( 제 2 보 )
이숭구(Sung Ku Lee),이윤하(Yoon Ha Lee),김진곤(Jin Gon Kim),서대원(Dae Won Soe),장태종(Tae Jong Jang),김윤권(Yun Kwon Kim),김소연(So Yon Kim),박병익(Byong Yik Park),이권전(Gwon Jun Lee) 대한내과학회 1995 대한내과학회지 Vol.49 No.2
Objectives: In the treatment of active pulmonary tuberculosis, it is difficult to determine when the active tuberculosis has became inactive. (67)Gallium lung scan is known to be useful in the diagnosis of active pulmonary tuberculosis. The grade of Galliumuptake, the time of loss of uptake and the relation to the stability of tuberculous lesion in the chest radiograph were followed to define the possibility of making early decision when active pulmonary tuberculosis became inactive Metheds: In 31 patients with active pulmonary tuberculosis, (67)Galliurn lung scan and chest radiograph were followed serially from June 1991 to October 1993. (67)Gallium lung scan and chest radiograph were followed serially from June 1991 to October 1993, (67)Gallium lung scan was performed 48 hours after intravenous injection of 3mCi of (67)Gallium citrate and classified into 4 grades according to the degree of up- take. Results: 1) In patients with active pulmonary tuberculosis, the grade of Gallium uptake in lung scan was proportional to the severity of lesion in chest radiograph. 2) The degree of (67)Gallium uptake in serial lung scan waned progressively while antituberculous chemotherapy was continued, and showed in loss of uptake in 83% of patients within 6 months of therapy 3) The loss of (67)Gallium uptake was observed simultaneously in most patients as the lesion in chest radiograph became stable. In 81% of patients, the interval between the time of loss of (67)Gallium uptake and Radiologic stabilization was less than one month. Conclusion : While antituberculous chemotherapy was given, the serial (67)Gallium lung scan might be useful in determining the activity of tuberculous lung lesion and in making earlier decision than chest radiograph. Conclusively, we consider Gallium lung scan as a valuable measure in assessing the effectiveness of antituberculous treatment.
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간경변증 환자에서 혈청 4형 Collagen-7S의 의의
차경석(Kyoung Seok Cha),한영찬(Young Chan Han),김영태(Young Tae Kim),이숭구(Sung Ku Lee),서대원(Dae Won Seo),김영중(Young Jung Kim),박병익(Beong Yik Park),조민구(Min Koo Cho) 대한소화기학회 1995 대한소화기학회지 Vol.27 No.3
Background/Aims: Cirrhosis is defined anatomically as a diffuse process with fibrosis and nodule formation. Although liver biopsy provides the evaluation of the degree of fibrosis, a simpler diagnostic method would be helpful for its invasive nature. The serum type IV collagen is known recently to indicate the activity of collagen synthesis in the process of fibrosis. This study aims to evaluate the usefulness of serum type IV collagen with the clinical and laboratory findings. Methods: A number of abnormalities were found to be statistically associated with the levels of serum type IV collagen. Included among the clinical abnormalities were pitting edema, ascites, splenomegaly, jaundice, and encephalopathy. The laboratory tests include albumin, tota1 bilirubin, prothrombin time, and alkaline phosphatase. Results: Significant correlations were found between the serum type IV collagen and the grade of the modified Childs classification(p0.05: between class A and B, class B and C, respectively), as well as the CCLI(comhined clinical and laboratory index, r=0.74, Y=6.78 +0.71X, p0.001). Conclusions: These results suggest that the serum type IV collagen may be a sensitive marker of fibrotic process and may reflect the present state and prognosis in cirrhosis. (Korean J Gastroenterol 1995;27:331 337)
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경미한 급성 두부외상환자에서 SPECT , q - EEG 및 CT의 비교
김소연(So Yon Kim),김영중(Young Jung Kim),이석호(Suk Ho Lee),김진석(Jin Seok Kim),문희승(Hee Seung Moon),이숭구(Sung Ku Lee),박병익(Byung Yik Park),이권전(Gwon Jeon Lee),김갑득(Kap Deuk Kim),김호전(Ho Joeng Kim),조경형(Kyeung Hyeung 대한핵의학회 1993 핵의학 분자영상 Vol.27 No.2
Functional cerebral impairments have been verified objectively by brain SPECT and q-EEG (quantitative electroencephalography). Microcerebral circulatory defects without anatomical changes cannot be detected by the brain CT or MRI. Brain SPECT using Tc-99m-HMPAO (Hexamethyl propyleneamine oxime) as a key radioisotope may be accepted as the useful method for identifying functional cerebral impairments. We studied 25 patients with mild head trauma to define whether the SPECT was helpful in detecting cerebral impairment. Results were as follows: The SPECT was positive in 23 patients out of 25, q-EEG positive in 16 patients and brain CT was positive in 3 cases. SPECT and q-EEG were more sensitive than CT. SPECT would be more useful method than brain CT to investigate cerebral function after head injury.
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염화 제2수은이 흰쥐 신장에서의 지질 과산화와 Catalase 활성도에 미치는 영향
이숭구,하경란,고현철,신인철,서대규 한양대학교 의과대학 1994 한양의대 학술지 Vol.14 No.2
In an attempt to define the early biochemical determinants that participate in the pathogenesis of mercuric chloride-induced nephrotoxicity, especially focusing on oxygen free radicals, we studies malondialdehyde(MDA) level and catalase activity in renal cortex of the rats at 24, 48 and 72 hr after the injection of mercuric chloride. Wistar albino rats weighing 180 to 220gm were injected subcutaneously with mercuric chloride(HgCl₂, 2mg/kg). The result obtained can be summarized as follows: 1.The group treated with mercuric chloride showed significantly lower MDA level at 24, 48 and 72hr after the infection as compared to that of control group. 2.The group treated with mercuric chloride showed significantly higher catalase activity at 24hr and lower catalase activity at 72hr after the infection as compared to that of control group. These results suggest that the excessive oxygen free radicals resulting from the depression of catalase activity is an important determinant in pathogenesis of mercuric chloride-induced nephrotoxicity.
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