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- 저자 : 이권전(Gwon Jun Lee) (검색결과 32 건)
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정상범위의 간기능검사치를 갖는 만성 B 형간염 보유자에서 간조직검사와 혈청 4 형 콜라겐치의 비교
송명준(Myung Jun Song),김경곤(Kyoung Gon Kim),신요식(Yo Sig Shin),황남철(Nam Cheol Hwang),박상준(Sang Joon Park),김윤권(Yun Kwon Kim),김소연(So Yon Kim),김영중(Young Jung Kim),조민구(Min Koo Cho),이권전(Gwon Jun Lee) 대한내과학회 2002 대한내과학회지 Vol.63 No.1
Background: We compared the results of liver biopsy and the levels of serum type Ⅳ collagen of the hepatitis B carriers with normal liver function test (LFT) to evaluate the clinical usefulness of serum type Ⅳ collagen in predicting the progression of histopathological findings. Methods: Thirty one chronic hepatitis B carriers with normal LFT and no significant clinical symptoms, who were Korean combat police, were classified into three groups according to their histologic results of the liver biopsies. The classification followed the standard proposed by Korean Society of Pathology. Blood samplings for serum type Ⅳcollagen (reference : less than 5 ng/mL) were done in the morning of the same day of the liver biopsy. Results: Of thirty one patients, thirteen patients showed normal histologic findings (41.9%, Group A), eleven patients revealed histologic abnormalities without fibrosis (35.5%, Group B) and seven patients were with fibrosis on liver biopsy (22.6%, Group C). Serum type Ⅳ collagen levels of Group A, B and C were 3.53±0.57 ng/mL, 3.56±1.17 ng/mL and 3.97±0.88 ng/mL, respectively. The average of serum type Ⅳ collagen levels of Group C was higher than of Group B and the average of Group B higher than that of Group A without any statistical significance (p>0.05). The averages of serum type Ⅳ collagen of eighteen patients with histologic abnormalities (Group B and C) and twenty four patients without fibrosis (Group A and B) were 3.73±1.06 ng/mL and 3.55±0.88 ng/mL respectively. Upon comparison of these averages with the those of Group A and C, no statistical significance was established (p>0.05). Conclusion: In chronic hepatitis B carriers with normal LFT findings, levels of serum type Ⅳ collagen were elevated along with histologic severities without statistical significance, therefore can not represent the changing degree of the histologic findings. Liver biopsy is considered to be one of the most accurate tool to assess the histologic status of the liver.(Korean J Med 63:29-35, 2002)
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활동성폐결핵 환자의 치료에 따른 67Gallium 폐주사의 음전시기의 의의 ( 제 2 보 )
이숭구(Sung Ku Lee),이윤하(Yoon Ha Lee),김진곤(Jin Gon Kim),서대원(Dae Won Soe),장태종(Tae Jong Jang),김윤권(Yun Kwon Kim),김소연(So Yon Kim),박병익(Byong Yik Park),이권전(Gwon Jun Lee) 대한내과학회 1995 대한내과학회지 Vol.49 No.2
Objectives: In the treatment of active pulmonary tuberculosis, it is difficult to determine when the active tuberculosis has became inactive. (67)Gallium lung scan is known to be useful in the diagnosis of active pulmonary tuberculosis. The grade of Galliumuptake, the time of loss of uptake and the relation to the stability of tuberculous lesion in the chest radiograph were followed to define the possibility of making early decision when active pulmonary tuberculosis became inactive Metheds: In 31 patients with active pulmonary tuberculosis, (67)Galliurn lung scan and chest radiograph were followed serially from June 1991 to October 1993. (67)Gallium lung scan and chest radiograph were followed serially from June 1991 to October 1993, (67)Gallium lung scan was performed 48 hours after intravenous injection of 3mCi of (67)Gallium citrate and classified into 4 grades according to the degree of up- take. Results: 1) In patients with active pulmonary tuberculosis, the grade of Gallium uptake in lung scan was proportional to the severity of lesion in chest radiograph. 2) The degree of (67)Gallium uptake in serial lung scan waned progressively while antituberculous chemotherapy was continued, and showed in loss of uptake in 83% of patients within 6 months of therapy 3) The loss of (67)Gallium uptake was observed simultaneously in most patients as the lesion in chest radiograph became stable. In 81% of patients, the interval between the time of loss of (67)Gallium uptake and Radiologic stabilization was less than one month. Conclusion : While antituberculous chemotherapy was given, the serial (67)Gallium lung scan might be useful in determining the activity of tuberculous lung lesion and in making earlier decision than chest radiograph. Conclusively, we consider Gallium lung scan as a valuable measure in assessing the effectiveness of antituberculous treatment.
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삼배체 염색체 이상을 보인 급성 림프구성 백혈병 1 예
전종구(Chong Ku Jun),차주영(Ju Young Cha),오형모(Hyung Mo Oh),신요식(Yo Shik Shin),김윤권(Yun Kwon Kim),김소연(So Yon Kim),김영중(Young Jung Kim),박병익(Byung Yik Park),조민구(Min Koo Cho),이권전(Gwon JUn Lee),이경인(Kyung In Lee),이은 대한내과학회 2001 대한내과학회지 Vol.61 No.2
In addition to age, white cell count and immunophenotype, karyotype has been reported to be one of the important prognostic factors in acute lymphocytic leukemias. Furthermore 70 percent of patients with acute B lymphocytic leukemia presented chromosomal abnormalities, which is known to have a close relationship with the prognosis. Among the abnormalities, triploid is rare and known to have the worse prognosis. Structural chromosomal abnormality of the 11q23 band is more common in childhood acute lymphocytic leukemia and has been rarely reported in adult lymphocytic leukemia. We present a case of a 29 year - old male patient with acute lymphocytic leukemia, who had triploid and chromosomal translocation including 11q23 band along with the review of related literature.(Korean J Med 61:190-194, 2001)
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전투 경찰에서 발생한 렙토스피라병 12 예에 대한 역학 및 임상적 고찰
장원규(Won Gyu Chang),송명준(Myung Jun Song),차영학(Young Hak Cha),김경곤(Kyoung Gon Kim),백운희(Un Hee Paik),김윤권(Yun Kwon Kim),김소연(So Yon Kim),김영중(Young Jung Kim),조민구(Min Koo Cho),이권전(Gwon Jun Lee) 대한내과학회 2001 대한내과학회지 Vol.61 No.5
Background: There were two occurrences of typhoon and the floods in Korea from early to late September, 2000. The Korean Combat Police and policemen participated in cleaning activities at the flooded area. Leptospirosis broke out among these participants . This study describes the epidemiological and clinical characteristics of leptospirosis patients among policemen. Methods: Of 16,750 individuals involved, 3,752 subjected to passive hemagglutination antibody (PHA) test at the Regional Health Care Units or the National Police Hospital. With 1 case of dead plus 12 cases which were turned out to be seropositive by PHA test and confirmed by microagglutination (MA) test, epidemiological and clinical characteristics were studied by questionnaire survey, laboratory test, and history of treatment while being hospitalized. Results: The seropositive rate of leptospira antibody was 0.3% (12/ 3,752). All 12 serpositives were bare-footed while working at the flooded area and of these, 8 patients (67%) were noticed abrasions either on hand or feet. However, no statistically significant correlation was found between the duration of outdoor activity and the seropositive rate (r=-0.46, p =0.36). There were clinical difference among patients who has the same serotype of leptospirosis, physical conditions, circumstance and the same work area. Two abnormal EKG results are present, the one who complained of chest pain is myocardial ischemia and the other who didn`t complain of any symptoms is sinus pause. Correlation between the febrile period before and the duration of fever after the use of antibiotics was estimated as ; febrile period after antibiotics use = 0.102804+0.995327×febrile period before antibiotics use (p =0.058). Conclusion: When leptospirosis is related to group activities, it is possible to educate in advance and to manage systematically afterwards, it may prevent the occurrence of leptospirosis or the related complications.(Korean J Med 61:553-561, 2001)
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겨울철에만 반복적으로 발생하였던 음식물의존성 운동유발성 아나필락시스
김준형 ( Joon Hyung Kim ),이재일 ( Jae Il Lee ),양병윤 ( Byeong Yoon Yang ),안석진 ( Seok Jin Ahn ),박상준 ( Sang Joon Park ),김소연 ( So Yon Kim ),이권전 ( Gwon Jun Lee ) 대한내과학회 2005 대한내과학회지 Vol.69 No.3
Food-dependent exercise-induced anaphylaxis has been recognized a variant of exercise-induced anaphylaxis charaterised by symptoms occuring on exertion after certain meal. We experienced a patient who developed an anaphylaxis induced by wheat flour made food followed by exercise only in cold temperature. A 22-year-old male patient was presented urticaria, angioedema, dyspnea, and loss of consciousness induced by exercise after ingestion of wheat flour made food only in winter. Skin prick test was negative for wheat or bread but positive for mushroom. By contrast, RAST was positive for wheat and negative for mushroom. In order to confirm the diagnosis exercise challenge test was done. The attack developed after ingestion of wheat flour made food and 10min of outdoor jogging in temperature about 10℃, but not by indoor treadmill test in temperature about 20℃ or ingestion of mushroom. This is the first case of food-dependent exercise-induced anaphylaxis developed only in cold temperature in Korea. (Korean J Med 69:330-334, 2005)
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