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강우헌,안병훈,정만표,김호중,권오정,이종헌,김진국,한정호,이경수,Kang, Woo-Heon,Ahn, Byung-Hoon,Chung, Man-Pyo,Kim, Ho-Joong,Kwon, O-Jung,Rhee, Chong-H.,Kim, Jhin-Gook,Han, Jung-Ho,Lee, Kyung-Soo 대한결핵및호흡기학회 1998 Tuberculosis and Respiratory Diseases Vol.45 No.1
We report a rare case of primary tracheal malignent melanoma documented by careful clinical examination. Differentiation between primary and metastatic malignant melanoma is very difficult We conclude that this tracheal tumor is a primary malignant melanoma based on characteristic pathologic features and the exclusion of the possibility of spontaneous regression of the primary site by patient's history and physical examination.
강우헌,김진석,최준환,김민정 대한류마티스학회 2006 대한류마티스학회지 Vol.13 No.4
Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease of unknown etiology, which affects skins, joints and other parts of body. Retinopathies associated SLE occur in 3.3% to 28% of cases, the incidence rising with the severity of systemic disease, and generally are found late in the disease. The most common findings described are cotton wool spots, retinal hemorrhages, and optic disc edema. We report two cases of SLE who had retinopathies as early manifestation of disease.
CAPD 환자에서 발생한 투석액의 흉강 누출에 의한 흉수 - 비디오 흉강경 ( VATS ) 과 Talc 를 이용한 흉막 유착술 1 예
강우헌(Woo Heon Kang),김정아(Jung Ah Kim),김대중(Dae Joong Kim),여호명(Ho Myoung Yeo),임영환(Young Hwan Lim),김범(Beom Kim),윤수진(Su Jin Yoon),이현희(Hyun Hee Lee),이영기(Young Ki Lee),오하영(Ha Young Oh) 대한신장학회 2002 Kidney Research and Clinical Practice Vol.21 No.5
Continuous ambulatory peritoneal dialysis (CAPD) is an effective renal replacement therapy for end-stage renal disease. Hydrothorax secondary to leakage of dialysate via pleuroperitoneal communication is a rare complication of CAPD. Earlier treatments of CAPD-induced hydrothorax have included pleurodesis with tetracycline, talc, fibrin, or autologous blood and surgical treatment. These procedure have made many patients switch to hemodialysis, because of the high relapse rate of the former and the invasiveness and morbidity of the latter. The talc pleurodesis with video-assisted thoracic surgery (VATS) allows not only direct visualization of potential diaphragmatic defect but also direct application of the talc to the visceral or parietal pleura. This procedure is less invasive than thoracotomy and can perform more accurate poudrage of talc than conventional methods. We have recently managed a patient CAPD-induced massive hydrothorax using thoracoscopic talc pleurodesis. This patient was successfully returned to CAPD.
신장내과 조기의뢰가 혈액투석 예후에 미치는 영향 : 단일 임상 기관 연구
강우헌 ( Woo Heon Kang ),오하영 ( Ha Young Oh ),신유정 ( You Jung Shin ),설정숙 ( Jeong Sook Seol ),강문자 ( Moon Ja Kang ),탁은영 ( Eun Young Tak ),이남선 ( Nam Sun Lee ),이미경 ( Mi Kyoung Lee ),류로사 ( Ro Sa Ryu ),송영혜 ( You 대한신장학회 2006 Kidney Research and Clinical Practice Vol.25 No.2
한국인에서 Iohexol의 혈장 청소율을 이용한 사구체 여과율의 측정
강우헌 ( Kang U Heon ),권태근 ( Kwon Tae Geun ),김대중 ( Kim Dae Jung ),강명재 ( Kang Myeong Jae ),백현정 ( Baeg Hyeon Jeong ),여호명 ( Yeo Ho Myeong ),임영환 ( Im Yeong Hwan ),김정아 ( Kim Jeong A ),이방훈 ( Lee Bang Hun ),김범 대한신장학회 2004 Kidney Research and Clinical Practice Vol.23 No.2
배 경 : Iohexol (Omnipaque^(?))은 혈장 청소율이 GFR과 일치하는 물질로, 서구에서는 iohexol의 배설단계의 혈장 농도와 그 반감기를 이용하여 혈장 청소율을 계산하고 이를 보정하여 GFR을 추정하고 있다 [Bro¨chner-Mortensen (B-M)법]. 그러나 아직 한국인을 대상으로 그 방법이 정립된 바 없으며 또 가장 적절하고도 편리한 혈장 농도 측정 시간 및 횟수에 대해서는 논란이 있는 실정이다. 이에 저자들은 iohexol외 혈장반감기를 이용한 위와 같은 측정법을 검체 횟수 및 시간 간격을 달리하여 한국인에 적용하였을 때 GFR 측정의 정확도 및 크레아티닌 청소율을 비롯한 여러 GFR 계측 공적들의 정확도를 다음과 같이 검증하였다. 방 법 : 신장질병이 없는 한국인을 대상으로 (n=19) iohexol 정주 후 HPLC로 측정한 14시점의 혈장 농도들을 이용하여 2구획 모델에 의한 iohexol의 혈장 청소율 (CL-T)을 구하였다. 이를 기준으로 첫째 배설단계의 8시점의 농도를 이용하여 B-M법으로 계산된 청소율 (CL-M8), 둘째 그 중 각각 3, 2시점의 농도를 가지고 같은 방법으로 계산된 청소율 (CL-M3, CL-M2), 셋째 CCr를 비롯한 여러 계측 공식들을 이용한 GFR 예측치를 비교하였다. 각 측정치의 정확도는 CL-T를 기준으로 하여 -0.1≤(측정값-CL-T)/CL-T≤0.1를 만족하는 정도 (%)로 평가하였다 (DOQI guideline). 결 과 : CL-T, CL-M8, CL-M3와 CL-M2는 각각 101.9±24.0, 101±18.7, 101.7±18.6,101.9±곤19.5 mL/min/1.73 ㎡로서 서로 차이가 없었으며 CL-M8의 정확도는 74%이었고, CL-M3, CL-M2의 정확도는 각각 84%, 79%로 상호간에 차이가 없었다. GFR 계측 공식 중에서는 MDRD 공식이 비교적 정확하였다 (47%). 결 론 : 이상에서 저자들은 신장질환이 없는 우리나라 사람을 대상으로 iohexol을 이용하여 B-M 보정법으로 사구체 여과율 측정하였을 때 2회의 검체 채취로도 정확하게 사구체 여과율을 측정할 수 있음을 확인하였으나 향후 GFR 값이 다양한 보다 많은 환자를 대상으로 추가 연구가 필요할 것으로 생각한다. Background : Plasma clearance of iohexol (Omnipaque^(?)) which used widely in radiologic procedure is considered as useful method for estimation of GFR because iohexol is neither reabsorbed nor secreted from tubule after filtered as inulin and its extrarenal clearance is negligible. Plasma clearance of iohexol can be calculated from two compartment model or one compartment model with Bro¨chner Mortensen (B-M) modification which convenient and reliable. But there were controversies about sufficient sampling numbers and times for B-M modification of iohexol clearance. Methods : Nineteen healthy Korean without renal disease underwent measurement of iohexol clearance. Iohexol was given as a single iv dose, and 14 blood sample were drawn up to 300 min. A reference GFR was iohexol clearance calculated from two-compartment model using 14 samples (CL-T). From 8, 3 and 2 samples clearances were calculated by B-M modification (CL-M8, 3 and 2 respectively). The accuracy of estimates was evaluated as percent of estimates falling within 10% above or below the reference GFR. Accuracy of CCr and equations for GFR estimation were also compared. Results : CL-T, CL-M8, CL-M3 and CL-M2 were not different (101.9±24.0, 101.9±18.7, 101.7±18.6, 101.9±19.5 mL/min/1.73 m² respectively). Accuracy of CL-M8, 3 and 2 were not different (74%, 84% and 79% respectively, p>0.05). MDRD equation had higher accuracy (47%) compared with other equations. Conclusion : These results indicate that sampling simplified method might be reduced to only two without accuracy loss in Korean without renal disease.
A Very Efficient Redundancy Analysis Method Using Fault Grouping
최형준,강우헌,강성호 한국전자통신연구원 2013 ETRI Journal Vol.35 No.3
To increase device memory yield, many manufacturers use incorporated redundancy to replace faulty cells. In this redundancy technology, the implementation of an effective redundancy analysis (RA) algorithm is essential. Various RA algorithms have been developed to repair faults in memory. However, nearly all of these RA algorithms have low analysis speeds. The more densely compacted the memory is, the more testing and repair time is needed. Even if the analysis speed is very high, the RA algorithm would be useless if it did not have a normalized repair rate of 100%. In addition, when the number of added spares is increased in the memory, then the memory space that must be searched with the RA algorithms can exceed the memory space within the automatic test equipment. A very efficient RA algorithm using simple calculations is proposed in this work so as to minimize both the repair time and memory consumption. In addition, the proposed algorithm generates an optimal solution using a tree-based algorithm in each fault group. Our experiment results show that the proposed RA algorithm is very efficient in terms of speed and repair.