VP-16으로 성공적으로 치료된 위 Kaposi 육종 1예

양웅석,송근암,조몽,이재승,송철수,김형욱,김영민,이수봉,김태오,이성훈 대한소화기내시경학회 1999 Clinical Endoscopy Vol.19 No.4

The skin is an uncommon site of distant metastasis from any internal malignancy, and the incidence of metastatic skin lesions as the first symptom of disease is only 0.8% in patients with all systemic malignancies. Furthermore, cutaneous metastasis from adenocarcinoma of the stomach has been found to be extremely rare. A 35-year-old female patient was admitted due to multiple cutaneous nodules in her chest, abdomen, and back. A gastroendoscopic examination and biopsy was made according to the results of skin pathologic findings. Stomach and skin biopsy results revealed a signet ring cell type of adenocarcinoma. A case of gastric adenocarcinoma in which metastatic skin nodules appeared as the first sign of disease, is here in reported with a review of related literature.

CA 125치가 증가된 난소종괴 환자에서 악성 감별을 위한 CA 15-3과 TAG 72의 효용성

이수미,김영탁,정동근,남주현,목정은 울산대학교 의과대학 1992 울산의대학술지 Vol.1 No.1

The purpose of our study was to evaluate whether the combined use of serum tumor markers, CA 15-3 and TAG 72 could improve the efficacy for discriminating malignant from benign ovarian masses in patients with elevated serum CA 125 levels. Serum CA 15-3 and TAG 72 were preoperatively measured by immunoradiometric assay in 78 patients with pelvic masses who had elevated serum CA 125 levels above 35 U/ml. In 32 patients with epithelial ovarian cancers, serum CA 125 levels were elevated above 65 U/ml in 97% and serum CA 15-3(>30U/ml) and TAG 72(>10 u/ml) levels were elevated in 59% and 50%, respectively, suggesting relatively low sensitivity of CA 15-3 and TAG 72. However, in 41 patients with benign ovarian tumors, elevations of these two markers were detected only in 7% and 5%, respectively, and particularly, both markers were not elevated among all the aptients over 50 years of age. Coordinate elevations of CA 125(>35U/ml) and CA 15-3(>30U/ml) or TAG 72(>10 U/ml) could discriminate epithelial ovarian cancers from benign masses with a sensitivity of 72% and specificity of 90%. Among patients over 50 years of age, sensitivity and specificity were increased to 79% and 100%, respectively. It is concluded that the combined use of CA 15-3 and TAG 72 with CA 125 could obtain an improved efficacy for discrimination of epithelial ovarian cancer, especially among patients over 50 years of age.

한국 민간기업 근로여성의 육아휴직활용 패턴 영향요인 연구 : 고용보험 DB 분석을 중심으로

이수영,이근주 梨花女子大學校 社會科學大學 社會科學硏究所 2011 사회과학연구논총 Vol.25 No.-

여성인력의 지속적인 사회 참여가 국가경쟁력 확보에 결정적인 영향을 미친다는 인식의 확산과 함께 결혼, 임신 및 출산 등 여성 인력의 사회 진출에 부정적인 영향을 미쳐왔던 여건들을 개선하기 위한 다양한 정책들이 도입되고 있다. 그 중에서도 대표적인 것으로 육아와 관련된 일·가정 양립의 어려움을 완화하여 여성이 퇴직의 불안 없이 지속적으로 사회 활동을 할 수 있도록 지원해주는 육아휴직제도를 들 수 있다. 육아휴직제도는 도입된지 20년이 지났지만 아직까지도 육아휴직제도가 활발하게 활용되어 정책 본래의 목적을 달성했는가에 대하여는 논란이 있다. 이에 본 연구는 육아휴직제도의 활용에 영향을 미치는 요인을 고용보험 D/B를 분석하여 규명해 보고 있다. 육아휴직 사용여부, 육아휴직 사용기간, 육아휴직 사용 후 복직여부를 종속변수로 하여 각각에 영향을 미치는 요인들을 회귀분석을 활용하여 분석한 결과는 다음과 같다. 우선, 육아휴직의 사용은 직업의 안정성과 경력개발 의지에, 육아휴직 사용기간은 직접양육 의지와 경력개발의지에, 육아휴직 사용 후 복직여부는 직업의 안정성과 직접양육 의지에 가장 큰 영향을 받는 것으로 나타났다. 특히 고용안정이 육아휴직의 사용, 사용기간 및 육아휴직 사용 후 복직 가능성에 결정적 영향을 미치는 것으로 나타났다. 분석 결과는 우리나라 육아휴직제도의 정책의 본래 목적을 달성하기 위한 제도적 개선 등 정책적 시사점을 제공하고 있다. Concerns for national competitiveness and low fertility initiated many government policies and programs intended to improve the working conditions of the women labor force. Parental leave is one of the representative programs that allows women to take care of the family and maintain the employment at the same time. This research tries to understand the factors affecting the usage of parental leaves. The analysis of three regression models with parental leave, the duration of usage, and reinstatement as dependent variables respectively, showed following implications. First, the use of parental leave is mostly affected by the stability of employment and the person’s will of career development. Second, duration of parental leave is influenced by the person’s will of direct bringing and also the will of career development. Finally, reinstatement at the end of the leave is affected by the stability of employment and the will of direct bringing. The stability of employment and career development seem to play important roles in making parental leave decisions. Policy implications are discussed and policy suggestions are made based on the result of the analysis.

랫드에서 법제유황과 비법제유황의 독성비교

김근수, 정유리, 이남진, 홍성희, 유종훈, 정재황, 강종구 충북대학교 동물의학연구소 2006 Journal of Biomedical and Translational Research Vol.7 No.2

본문참고

이단하소에 의해 제조된 PNN-PZ-PN 세라믹의 압전 및 유전특성

이수호,손무헌,조현철,김한근,사공 건 東亞大學校 1997 東亞論叢 Vol.34 No.-

In the fields of the optics, precise machine, semiconductors, the micro-positioning actuators are required for the control of position in submicron range. PNN-PZN-PZT cermics were fabricated with various mole ratio of the PZT[Pb(Zr½ Ti½)O₃] PNN[Pb(Ni⅓Nb⅔)O₃]and PZN[Pb(Zn⅓Nb⅔)O₃]powders prepared by double calcination and PZT powders prepared by molten-salt synthesis method. The formation rate of perovskite phase in PNN-PZN-PZT ceramics could be obtained about 92% at PZT 0.3 mole ratio. The relative permittivity of specimen with PZT 0.3 mole ratio was shown 5,320 and appeared the relaxor ferroelectric feature. The maximum piezoelectric coefficient d₃₁to be used for evaluation the displacement of piezoceramics in PNN-PZN-PZT ceramics was 324×10¹²(C/V) at the vicinity of morphotropic phase boundary and was larger than that of solid PZT ceramics(120×10-¹²C/V).

기도내 이물(껌) 제거후 발생한 급성 재확장성 폐부종 1치험례

이동건,이재우,이일우,왕수건 釜算慶南耳鼻咽喉科學會 1996 임상이비인후과 Vol.7 No.2

삼차신경 감각핵의 세포활성도와 Substance P 유리에 대한 Capsaicin, Paradol 및 Shogaol의 전통작용기전에 관한 연구 : Ⅰ. 유해자극에 의한 개구반사와 삼차신경 척수감각핵의 Substance P에 미치는 영향 Ⅰ. EFFECTS ON JAW OPENING REFLEX BY NOXIOUS STIMULUS AND RELEASE OF SUBSTANCE P

이종흔,김중수,송형근,박수정,함진숙 대한구강생물학회 1990 International Journal of Oral Biology Vol.14 No.1

The purpose of this investigation was to determine the relative analgesic effectiveness of paradol and shogaol compared with capsaicin, and effects of capsaicinoids on substance P of trigeminal spinal sensory nucleus. Under anesthesia, anterior belly of digastric muscle was exposed and a pair of electrodes was inserted to record the electromyograms. Noxious electrical stimulus was applied to oral mucosa around the mental foramen. Inferior alveolar nerves (IAN) and saphenous nerves were carefully exposed for application of vehicle and drugs to evaluate the effects on digastric EMG (dEMG) and neural conduction, and caudal part of brainstem was exposed to determine the substance P. Vehicle and 1.5% of capsaicin, paradol and shogaol were applied to IAN and saphenous nerves for 30 minutes, respectively. EMG_s of digastric muscle evoked by noxious electrical stimulus were recorded before application of drugs or vehicle, immediately after removal and washing of drugs and at 30 minutes after washing. To examine the effects of the peripheral stimulation on the action potential, stimulating electrodes were placed on the peripheral side of drugs application site and recording electrodes were on the proximal side. Substance P of trigeminal spinal sensory nucleus was collected by push-pull perfusion technique and determined by radioimmunoassay. Capsaicin application on IAN could not influence on dEMG, but paradol and shogaol decrease the amplitude of dEMG. Capsaicin applied locally to nerve decreased amplitude and conduction velocity of only C-fiber, while paradol and shogaol inhibited the neural conduction of C-fiber and Aδ-fiber. Substance P in the trigeminal spinal nucleus was reduced by capsaicin but not by paradol and shogaol.

조직확장술및 장골이식을 이용한 하악골 결손부의 재건

이계영,민경인,정수일,박재범,안재진,김도균,김철환 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.4

Soft tissue expansion is widely used technique in oral & maxillofacial reconstruction and provide new method of reconstruction in posttraumatic alopecia, post burn, wide scar, congenital deformity, benign tumor, tattoo, etc. Expanded tissue flaps have the advantage of increased vascularity, proximity to the defect, and similarity of color and texture. They also preclude the need to advance flaps from distant sites. Tissue expansion can be used to form a well vascularized cavity to accomodate and nourish bone grafts. The following report describes the uses of tissue expanders by allowing bone grafting to correct both soft and bony defects of mandibular region

영어 등위구조에서의 추출 현상

이남근,정수영 조선대학교 인문학연구소 1998 外國文化硏究 Vol.21 No.1

등위구문은 피접속요소가 서로 대등한 문법적 관계로 접속되는 구조로서 모든 언어에 산재하는 현상으로 많은 언어이론의 연구대상이 되어왔다. 그러나 등위구문을 분석함에 있어서 어떠한 시각에서 접근할 것인가에 대해 견해는 아주 다양하다. 현대 통사론에서 등위구문은 매우 중요한 문제로 다루어져 왔으며 가장 논란이 많은 문제 중의 하나일 것이다. 통사적인 제약이 가해져서 추출이 이루어진다고 판단하는 견해와 의미론적인 또는 화용론적인 관념들이 적용되어서 등위구문에서의 추출이 이루어진다는 견해등이 있다. Ross(1967)가 등위구조제약과 같은 조건을 제시한 이후로 지금껏 많은 학자들이 영어의 등위구조에서의 추출현상을 여러 각도에서 연구를 거듭하여 왔다. 그중에는 등위구조에서의 추출을 의미론적인 면과 화용론적인 면에서 접근하는 학자들이 많이 있다. 이 논문에서는 Lakoff(1986)나 Goldsmith(1985)와 같은 학자들의 의미론적인 입장과 Schmerling(1976)의 화용론적인 입장에서 영어에서의 등위구조의 추출현상을 다룬다. 영어의 등위구문에서의 추출 현상을 본석함에 있어서 이 세가지 측면에서의 분석을 논의하고 각각의 문제점을 제시하고자 한다. Coordinate structures consist of more than two conjuncts. Ross suggested that a conjunct cannot be moved and any element in a conjunct cannot be extracted from that conjunct. The first part of the Coordinate Structure Constraint, the Conjunct Constraint, prevents extraction of a whole conjunct, and the second part, the Element Constraint, prohibits extraction of any element in a conjunct. But not all languages follow that constraint. Ross admitted there is an exception : extraction out of conjuncts is possible only if the extraction is Across The Board. That is, the extraction out of coordinate structures is well-formed only if elements are extraction out of coordinate structures is well-formed only if elements are extracted out of all conjuncts. Violations of the Element Constraint are allowed just in case the ATB condition is met. But not all sentences follow the Coordinate Structure Constraint, the exception of that constraint being Ross's Across The Board. Thus, the fundamental problem is raised of whether the coordinate structure constraint really exists. On this, Goldsmith and Lakoff suggested that the extraction from the coordinate structure can be justified if coordinate sentences are related with some sort of semantic or pragmatic conditions instead of syntactic constraints. It is accepted that coordinate sentences have something to do with some semantic or pragmatic presuppositions like sequentiality.

소아 확장성 심근증의 임상적 고찰

이성환,김준식,박근수,김명성,권태찬,김천수,이상락 啓明大學校 醫科大學 1996 계명의대학술지 Vol.15 No.1

A Clinical assessment of the 25 patients with dilated cardiomyopathy who were admitted to the Department of Pediatrics, Keimyung University Dong San Hospital from January, 1982 to June, 1993 was performed. The result were as follows: 1) Among 25 patients with dilated cardiomyopathy. 8(32%) were younger than 1 year of age at the time of admission. 2) Adriamycin toxicity was the only encountered etiologic factor in 1 patient. 3) On admission, hepatomegaly and tachycardia were noted in almost all patients. 4) The Chest X-rays showed cardiomegalies in all 25 patients, pulmonary vein congestions in 15(60%) and pleural effusion in 2(8%). 5) The electrocardiography showed left ventricular hypertrophy in 72% and supraventricular tachycardia in 32%. 6) The echocardiographic examination showed left ventricular dilatations in all patients and left atrial dilatations in 20(80%). 7) Of 18 patients who had followed mean period of 2.9 years, 10 patients died within 9 months after the diagnosis.