한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고

양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

동결견(凍結肩) 환자의 동서협진 치료의 임상효과 비교연구 : 견관절 가동운동범위(ROM) 변화를 중심으로

남동우,김행범,양동훈,임사비나,김건식,이두익,이재동,최도영,이윤호 경희대학교 동서의학연구소 2006 東西醫學硏究所 論文集 Vol.2006 No.-

Objectives : To establish an effective collaborate medicine treatment of acupuncture and western medicine for treating frozen shoulder patients. Methods : 59 voluntary patients were randomly assigned to Eastern treatment group(E group, n=22), Western treatment group(W group, n=17) and East-West treatment group(EW group, n=20). The E group received acupuncture treatment on LI15, TE14, GB21 and Master Dong's acupuncture points, Shin-gwan and Gyun-joong, twice a week for 4 weeks. The W group received suprascapular nerve block, subacromial injection and trigger point injection, twice a week for 4 weeks. The EW group received acupuncture and injection treatment including nerve block. All groups were instructed to practice self exercise during their daily lives. Evaluations were made before treatment and after treatment based on the change in shoulder Range of Motion(ROM) and the patient's satisfaction concerning the treatment was measured by Visual Analogue Scale(VAS). The obtained data were analyzed and compared. Results : The patient's satisfaction scores were E group 5.67, W group 7.73 and EW group 7.67. The E group and the EW group showed significant improvement in abbduction, adduction and flexion(p<0.05). The W group showed significant improvement in adduction(p<0.05). Abduction significantly improved(p<0.05) in the EW group compared to E group and W group. Flexion also showed improvement in the EW group, but the difference among the 3 groups was statistically insignificant. The three group's difference of change in extension and adduction was insignificant(p>0.05). Conclusion : Acupuncture and nerve block alone significantly improved ROM in frozen shoulder patients. Also collaborate treatment of acupuncture and nerve block significantly improved ROM in frozen shoulder patients. But the difference of the three treatments were significant only for improving abduction(p<0.05).

동결견(凍結肩) 환자의 동서협진 치료의 임상효과 비교연구 - 견관절 가동운동범위(ROM) 변화를 중심으로 -

남동우,김행범,양동훈,임사비나,김건식,이두익,이재동,최도영,이윤호,Nam, Dong-Woo,Kim, Haeng-Beom,Yang, Dong-Hoon,Lim, Sa-Bi-Na,Kim, Keon-Sik,Lee, Doo-Ik,Lee, Jae-Dong,Choi, Do-Young,Lee, Yun-Ho 대한침구의학회 2006 대한침구의학회지 Vol.23 No.5

Objectives : To establish an effective collaborate medicine treatment of acupuncture and western medicine for treating frozen shoulder patients. Methods : 59 voluntary patients were randomly assigned to Eastern treatment group(E group, n=22), Western treatment group(W group, n=17) and East-West treatment group(EW group, n=20). The E group received acupuncture treatment on LI15, TE14, GB21 and Master Dong's acupuncture points, Shin-gwan and Gyun-joong, twice a week for 4 weeks. The W group received suprascapular nerve block, subacromial injection and trigger point injection, twice a week for 4 weeks. The EW group received acupuncture and injection treatment including nerve block All groups were instructed to practice self exercise during their daily lives. Evaluations were made before treatment and after treatment based on the change in shoulder Range of Motion(ROM) and the patient's satisfaction concerning the treatment was measured by Visual Analogue Scale(VAS). The obtained data were analyzed and compared. Results : The patient's satisfaction scores were E group 5.67, W group 7.73 and EW group 7.67. The E group and the EW group showed significant improvement in abbduction, adduction and flexion(p<0.05). The W group showed significant improvement in adduction(p<0.05). Abduction significantly improved(p<0.05) in the EW group compared to E group and W group. Flexion also showed improvement in the EW group, but the difference among the 3 groups was statistically insignificant. The three group's difference of change in extension and adduction was insignificant(p>0.05). Conclusion : Acupuncture and nerve block alone significantly improved ROM in frozen shoulder patients. Also collaborate treatment of acupuncture and nerve block significantly improved ROM in frozen shoulder patients. But the difference of the three treatments were significant only for improving abduction(p<0.05).

하부가열 수평유체층에서 자연대류 유동에 관한 수치해석

양종훈,이동원,김양훈,현명택,김신 濟州大學校 工科大學 産業技術硏究所 1998 尖端技術硏究所論文集 Vol.9 No.1

The natural convection driven by a thermal buoyancy force was investigated in a square cavity. The top and bottom walls are cold and hot, respectively, while the vertical boundaries are adiabatic. A control volume approach with a power-law scheme was used to formulate the finite difference equations. The results are presented isotherms, velocity vectors, Nusselt numbers and critical Rayleigh numbers for the ranges of Ra = 1750 ∼ 20000 and Pr = 0.05 ∼ 10.0. The critical Rayleigh number increases as Prandtl number decreases. There exists a clockwise unicell flow near critical Rayleigh number, while two cells appear for large Rayleigh number.

납에 의해 유발된 신경세포의 APOPTOSIS

양선희,신동훈,백원기 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.2

Lead is a major environmental and occupational neurotoxicant. It has been shown that long-term exposure to a low level of lead impairs the development of brain. For example, it was reported that lead exposure during the childhood causes a learning difficulty and a memory deficit of children. Neurotoxic agents including the lead are believed to cause neuronal death in developing brain by two mechanisms: apoptosis and necrosis. However, the exact mechanism of neuronal death caused by lead exposure is still not known explicitly. In this study, we conducted a study to clarify a mechanism of hippocampal neuronal cell death caused by lead acetate. Hippocampal neurons were cultured for 14-16days and treated with lead acetate of 1, 10, 100μM concentrations for 12 hours. With the MTT (methyl tetrazolium test)kit, the viability of neuronal cells was measured. Next, in order to examine apoptosis caused by lead acetate, TUNEL(TdT-mediated d-UTP Nick End Labelling ) assay was performed. It has been shown that lead acetate reduced the viability of neuronal cells in a dose dependent manner, especially at the concentration of 100 μM lead acetate. TUNEL immunostain showed brownish signals in the nucleus of apoptotic cells. The proportions of apoptotic cells in the lead-acetate treated group were more higher than those in the controls and increased as lead acetate concentration increased. From above results, it may be concluded that lead in the hippocampal neuronal cells reduced cell viability and one of mechanisms in neuronal cell death by lead appears to be apoptosis.

하부가열 수평유체층에서 자연대류 유동에 관한 수치해석

양종훈,이동원,김양훈,현명택,김신 濟州大學校 産業技術硏究所 1998 산업기술연구소논문집 Vol.9 No.1

The natural convection driven by a thermal buoyancy force was investigated in a square cavity. The top and bottom walls are cold and hot. respectively. while the vertical boundaries are adiabatic. A control volume approach with a power-law scheme was used to formulate the finite difference equations. The results are presented isotherms. velocity vectors, Nusselt numbers and critical Rayleigh numbers for the ranges of Ra = 1750~20000 and Pr = 0.05~10.0. The critical Rayleigh number increases as Prandtl number decreases. There exists a clockwise unicell flow near critical Rayleigh number, while two cells appear for large Rayleigh number.

GIS에 의한 구조물의 최적 위치 결정 기법

양인태,김연준,김동문,박재훈 江原大學校 産業技術硏究所 1997 産業技術硏究 Vol.17 No.-

Local administration is closely related with intention of residents. Especially, a plan item is closely related with life of residents. Therefore, it has to be logical and objective solution for opinion convergence. Decision of opinion has to be in a triangular position standard and stand in a trio of criteria in standard. But, opinion convergence of residents very difficult. Recently, the technique of GIS presents method for opinion convergence with logical and objective and scientifically solution. And, this study present method for decision of intention to a complex element with GRID and NETWORK techniques of GIS. This study present optimun site of constructure with the GIS technique in consideration of a side face of transportation, technical, social economy and environments.

SEM과 3차원 재구성법을 이용한 수복면의 위치와 와동 크기에 따른 미세누출도 분석

양인서,신동훈 大韓齒科保存學會 2005 Restorative Dentistry & Endodontics Vol.30 No.2

This study was done to evaluate whether there were any differences in microleakage of class V composite restorations according to restoration site and cavity size. Total sixty-four restorations were made in molar teeth using Esthet-X. Small (2x2x1.5mm) and large (4x2x1.5mm) restorations were made at the buccal/lingual surface and the proximal surface each. After 1,000 times of thermocycling (5℃-55℃), resin replica was made and the percentage of marginal gap to the whole periphery of the restoration was estimated from SEM evaluation. Thermocycled tooth was dye penetrated with 50% silver nitrate solution. After imbedding in an auto-curing resin, it was serially ground with a thickness of 0.25 mm. Volumetric microleakage was estimated after reconstructing three dimensionally. Two-way ANOVA and independent T-test for dye volume, Mann-Whitney U test for the percentage of marginal gap, Spearman's rho test for the relationship between two techniques were used. The results were as follows : 1. The site and size of the restoration affected on the microleakage of restoration. Namely, much more leakage was seen in the proximal and the large restorations rather than the buccal/lingual and the small restorations. 2. Close relationship was found between two techniques (Correlation coefficient = 0.614/ P = 0.000). Within the limits of this study, it was noted that proximal and the large restorations leaked more than buccal/lingual and the small restorations. Therefore, it should be strictly recommended large exposure of margins should be avoided by reducing unnecessary tooth reduction. 본 연구에서는 수복면의 위치와 와동의 크기에 따른 미세누출도의 차이를 확인하기 위해 3차원 재구성법에 의한 색소침투량과 주사전자현미경 검경을 통한 변연틈새의 비율을 측정하였다. 32개의 건전한 대구치의 협/설면과 인접면에 각기 2x2x1.5mm 의 작은 와동과 4x2x1.5mm크기의 큰 5급 와동을 형성 한 다음, 자가부식형 접착시스템으로 치면 처리하고 혼합형 복합레진인 Esthet X로 단일 충전하였다. 5도와 55도 사이에서 1000회의 열순환을 시킨 다음, 레진 복제물을 제작하고 SEM 검경을 통해 전체 변연길이에 대한 변연틈새의 비율을 측정하였다. 또한 열순환된 치아에 질산은 용액으로 색소를 침투시킨 후 자가중합형 레진에 포매하여 0.25 mm두께의 간격으로 연속적으로 갈아내면서 각각의 단면상을 채득하였다. 각 단면상을 3차원으로 재구성하여 미세누출도를 정량적으로 평가하였다. 3차원 색소 침투량의 유의성 검정에는 Two-way ANOVA와 independent T-test를, 변연틈새의 비율에는 Mann-Whitney U test를 사용하였으며 , 두 방법 사이의 Spearman's rho test로 평가하여 다음과 같은 결과를 얻었다. 1. 미세누출도는 수복면의 위치와 와동의 크기에 의해 영향을 받았다. 즉 협/설면과 작은 와동보다는 인접면과 큰 와동에서 더 많은 미세누출을 보였다. 2. 두 방법 사이에는 높은 상관 관계를 보였다 (상관계수 = 0.614/P= 0.000). 이상의 연구 결과로 볼 때, 협/설면과 작은 와동의 수복물보다는 인접면과 큰 와동의 수복물에서 더 많은 미세누출을 보였으므로, 불필요한 치질 삭제를 줄임으로써 변연부의 노출이 커지는 것을 막아야 할 것이다.

병원간접원가의 예측수단으로서의 회귀식 모형과 인공신경망 모형에 대한 비교연구

양동현,박광훈,김선민 한국병원경영학회 1999 병원경영학회지 Vol.4 No.2

This research aims to compare between regression and neural network in terms of the predictive ability of the overhead costs in hospitals. For this purpose, this research uses the number of out-patients and complex medical treatments as explaining variables. Thirty-one hospitals were used for the empirical test. The test result shows that the regression model has a more predictive ability than the neural network.

경부도상 피판을 이용한 구강내 결손부의 재건

양동규,신상훈,서종천,이성근,김종렬 大韓顎顔面成形再建外科學會 1995 Maxillofacial Plastic Reconstructive Surgery Vol.17 No.3

Various cutaneous as well as myocutaneous flaps have been designed for the reconstruction of tissue defects caused by the excision of oral cancer. Among these flaps, cervical island skin flap have been introduced by Farr et al and more have developed by Tashiro et al. This flap has many advantages. The flap minimizes donor size by use of cervical operation wound, flap size available is adequate for most oral defects and the procedure is relatively simple and time saving. However, this flap is not applicable in patients where there are large tissue defects and metastasis is suspected. We used this flap for it's rapid simple, and effective, primary closure of oral defects after cancer ablation and we have found this flap very useful for the reconstruction of relatively small oral defects.