한국 해군의 협동교전능력(CEC) 발전방향에 관한 연구

남동우 해군대학 2002 海洋戰略 Vol.- No.114

오늘도 육아 전쟁은 시작되었다

남동우 부산여성가족개발원 2017 여성우리 Vol.- No.57

광역센터, 지역경영 선도의 주체

남동우 한국지방재정공제회 2022 지방재정 Vol.2022 No.1

2D 이미지와 3D 포인트 클라우드 매칭을 위한 대조 학습

남동우,노상준,백승혁,이규빈 제어로봇시스템학회 2022 제어로봇시스템학회 국내학술대회 논문집 Vol.2022 No.6

동결견(凍結肩) 환자의 동서협진 치료의 임상효과 비교연구 - 견관절 가동운동범위(ROM) 변화를 중심으로 -

남동우,김행범,양동훈,임사비나,김건식,이두익,이재동,최도영,이윤호,Nam, Dong-Woo,Kim, Haeng-Beom,Yang, Dong-Hoon,Lim, Sa-Bi-Na,Kim, Keon-Sik,Lee, Doo-Ik,Lee, Jae-Dong,Choi, Do-Young,Lee, Yun-Ho 대한침구의학회 2006 대한침구의학회지 Vol.23 No.5

Objectives : To establish an effective collaborate medicine treatment of acupuncture and western medicine for treating frozen shoulder patients. Methods : 59 voluntary patients were randomly assigned to Eastern treatment group(E group, n=22), Western treatment group(W group, n=17) and East-West treatment group(EW group, n=20). The E group received acupuncture treatment on LI15, TE14, GB21 and Master Dong's acupuncture points, Shin-gwan and Gyun-joong, twice a week for 4 weeks. The W group received suprascapular nerve block, subacromial injection and trigger point injection, twice a week for 4 weeks. The EW group received acupuncture and injection treatment including nerve block All groups were instructed to practice self exercise during their daily lives. Evaluations were made before treatment and after treatment based on the change in shoulder Range of Motion(ROM) and the patient's satisfaction concerning the treatment was measured by Visual Analogue Scale(VAS). The obtained data were analyzed and compared. Results : The patient's satisfaction scores were E group 5.67, W group 7.73 and EW group 7.67. The E group and the EW group showed significant improvement in abbduction, adduction and flexion(p<0.05). The W group showed significant improvement in adduction(p<0.05). Abduction significantly improved(p<0.05) in the EW group compared to E group and W group. Flexion also showed improvement in the EW group, but the difference among the 3 groups was statistically insignificant. The three group's difference of change in extension and adduction was insignificant(p>0.05). Conclusion : Acupuncture and nerve block alone significantly improved ROM in frozen shoulder patients. Also collaborate treatment of acupuncture and nerve block significantly improved ROM in frozen shoulder patients. But the difference of the three treatments were significant only for improving abduction(p<0.05).

8-Hydrocalamenene, Derived from Reynoutria elliptica, Suppresses Constitutive STAT3 Activation, Inhibiting Proliferation and Enhancing Chemosensitization of Human Multiple Myeloma Cells

남동우,송준호,김성무,Shu Yuan Chiang,김지성,정원석,장형진,정상훈,나영순,김성훈,심범상,안광석 한국식품영양과학회 2014 Journal of medicinal food Vol.17 No.3

The identification of the active compounds of herbal medicines and the molecular targets of those compounds is an attractive therapeutic objective. Reynoutria elliptica has been used for the treatment of various inflammatory diseases as a Korean folk remedy. Based on the evidence that anti-inflammatory agents frequently exert antiproliferative activity, we tested two sesquiterpene derivatives, 8-hydrocalamenene (HC) and 8,14-dihydrocalamenene (DHC), for their ability to induce apoptosis and suppress signal transducer and activator of transcription 3 (STAT3) activation in multiple myeloma (MM) U266 cells. We found that HC inhibited cell viability in U266, but not in peripheral blood mononuclear cells. HC exerted significant cytotoxicity and induced substantial subG1-phase arrest and apoptosis as compared with DHC. HC inhibited the expression of gene products involved in antiapoptosis (Bcl-2 and Bcl-xL), proliferation (cyclin D1), and invasion (MMP-9), all of which are known to be regulated by STAT3. Furthermore, HC up-regulated cyclin-dependent kinase inhibitor p21 and induced apoptosis through the activation of caspase-8, -9, and -3 in U266 cells. Interestingly, HC blocked constitutive STAT3 activation through the inhibition of activation of upstream kinases Janus-like kinase 1 ( JAK1), JAK2, and c-Src and up-regulated PIAS3. Deletion of STAT3 reversed cytotoxic effects and the down-regulation of cyclin D1 and c-myc by HC in MM cells. Finally, this sesquiterpene significantly synergized the cytotoxic and apoptotic effects of bortezomib in U266 cells. Taken together, these results suggest that HC is a novel blocker of STAT3 activation which may have a potential in the prevention and treatment of MM.

유착성 관절낭염 치료에 있어서 한방 치료와 양방 치료의 임상적 고찰 : 동서협진 모델 개발을 위한 기초 연구를 중심으로

남동우,정인태,김주희,박유선,임사비나,이두익,이재동,이윤호,최도영 경희대학교 동서의학연구소 2006 東西醫學硏究所 論文集 Vol.2006 No.-

Objectives : To observe the effect of acupuncture treatment and western medical treatment on frozen shoulder patients. Methods : 39 voluntary patients were randomly assigned to the Eastern treatment group(E group, n=22) and the Western treatment group(W group, n=17). The E group received acupuncture treatment on LI15, TE14, GB21 and Master Dong's acupuncture points, Shin-gwan and Gyun-joong, twice a week for 4 weeks. The W group received suprascapular nerve block, subacromial injection and trigger point injection, twice a week for 4 weeks. Both groups were instructed to practice self exercise during their daily lives. Evaluations were made before treatment and after treatment using Constant Shoulder Assessment(CSA), Shoulder Pain and Disability Index(SPADI) and the patient's satisfaction concerning the treatment was measured by Visual Analogue Scale(VAS). The obtained data were analyzed and compared. Results : The E group showed significant improvement(p<0.05) according to the CSA and SPADI. The patient's satisfaction scored 5.67 on a scale of 10. The W group showed significant improvement(p<0.05) according to the CSA and SPADI. The patient's satisfaction scored 7.73. But the difference between the two groups were insignificant according to CSA and SPADI. Conclusion : Both acupuncture and nerve block treatment significantly improved frozen shoulder. But the difference of the two treatments was insignificant.

동결견(凍結肩) 환자의 동서협진 치료의 임상효과 비교연구 : 견관절 가동운동범위(ROM) 변화를 중심으로

남동우,김행범,양동훈,임사비나,김건식,이두익,이재동,최도영,이윤호 경희대학교 동서의학연구소 2006 東西醫學硏究所 論文集 Vol.2006 No.-

Objectives : To establish an effective collaborate medicine treatment of acupuncture and western medicine for treating frozen shoulder patients. Methods : 59 voluntary patients were randomly assigned to Eastern treatment group(E group, n=22), Western treatment group(W group, n=17) and East-West treatment group(EW group, n=20). The E group received acupuncture treatment on LI15, TE14, GB21 and Master Dong's acupuncture points, Shin-gwan and Gyun-joong, twice a week for 4 weeks. The W group received suprascapular nerve block, subacromial injection and trigger point injection, twice a week for 4 weeks. The EW group received acupuncture and injection treatment including nerve block. All groups were instructed to practice self exercise during their daily lives. Evaluations were made before treatment and after treatment based on the change in shoulder Range of Motion(ROM) and the patient's satisfaction concerning the treatment was measured by Visual Analogue Scale(VAS). The obtained data were analyzed and compared. Results : The patient's satisfaction scores were E group 5.67, W group 7.73 and EW group 7.67. The E group and the EW group showed significant improvement in abbduction, adduction and flexion(p<0.05). The W group showed significant improvement in adduction(p<0.05). Abduction significantly improved(p<0.05) in the EW group compared to E group and W group. Flexion also showed improvement in the EW group, but the difference among the 3 groups was statistically insignificant. The three group's difference of change in extension and adduction was insignificant(p>0.05). Conclusion : Acupuncture and nerve block alone significantly improved ROM in frozen shoulder patients. Also collaborate treatment of acupuncture and nerve block significantly improved ROM in frozen shoulder patients. But the difference of the three treatments were significant only for improving abduction(p<0.05).

이개유리피판을 이용한 비 결손부 재건

남동우,이종욱,범진식,장영철,정철훈,오석준,Nam, Dong-Woo,Lee, Jong-Wook,Burm, Jin-Sik,Chang, Young-Chul,Chung, Chul-Hoon,Oh, Suk-Joon 대한미세수술학회 1996 Archives of reconstructive microsurgery Vol.5 No.1

The nasal ala and columella represent a difficult location for reconstruction, especially when defect area is covered with scar. Local flap, such as forehead flap or nasolabial flap, may result in additional facial scarring and bulkiness that require multiple thinning revisions. Recent delineation of vascular territories of the ear has allowed the use of vascularized auricular free flap in the reconstruction of large ala and columella defects. Authors reconstructed two cases of full thickiness defect of the ala and columella with auricular free flap. The pedicle of this flap is the superficial temporal artery and vein. The donor vessels were anastomosed to the facial artery and vein. The results were satisfactory cosmetically and functionally.

러시아·우크라이나 갈등의 역사적 근원과 러시아의 우크라이나 침공이한반도 안보에 주는 전략적 함의

남동우,김덕기 인문사회 21 2022 인문사회 21 Vol.13 No.2

A Study on the Historical Origins of Russia-Ukraine Conflictand Strategic Implications of Russia’s Invasion of Ukrainefor Security on the Korean PeninsulaDongwoo Nam & Dukki Kim Abstract: The purpose of this study is to examine the historical origins of the Russia and Ukraine conflict and suggest strategic implications for the security of the Korean Peninsula after analyzing why Russia invaded Ukraine, which has geopolitical situation similar to the Korean Peninsula. Russia demanded the US and the West to reject Ukraine’s accession to NATO and halt NATO’s eastward movement, but Washington and EU refused to accept them. Russia finally invaded Ukraine on the pretext that the US and the West had rejected its requirements. In particular, the Ukraine crisis is a good example of how the strategic failure of a weaker nation sandwiched between great powers will cost a lot. On Balance, the Ukraine crisis has become the arena of the Great Game in the 21st century, in which the United States and Russia compete for world supremacy. We must do our best so that the Korean Peninsula does not become the arena of hegemonic competition like the 19th century. In particular, we must solve the North Korean nuclear issue based on the strong ROK-US alliance and the united people’s strength. And in order to minimize conflicts with neighboring countries and maximize national interests, we must proactively conduct strong diplomacy with stronger national defense power and strategic thinking than ever before. Key Words: Russia, Ukraine, Korean Peninsula, United States, NATO 러시아·우크라이나 갈등의 역사적 근원과 러시아의 우크라이나 침공이한반도 안보에 주는 전략적 함의남 동 우*ㆍ김 덕 기** 요약: 본 논문의 연구목적은 러시아와 우크라이나 갈등의 역사적 근원을 살펴보고, 러시아가 왜 한반도와 유사한 지정학적 환경을 가진 우크라이나를 침공했는가를 분석한 후에 한반도 안보에 주는 전략적 함의를 제시하는 데 있다. 러시아는 미국과 서방에 우크라이나의 NATO 가입 거부, NATO의 동진(東進) 중단 등을 요구하고, 미국과 서방이 거부하자 이를 핑계로 우크라이나를 침공했다. 특히 이번 우크라이나 사태는 강대국 간 충돌에 놓인 약소국의 전략적 오류가 얼마나 큰 비용을 지급하게 되는지를 보여주는 좋은 사례다. 결론적으로 최근 우크라이나 사태는 미국과 러시아가 세계 패권을 놓고 경쟁하는 21세기 Great Game의 장(場)이 되고 있다. 우리는 한반도가 19세기처럼 강대국 간 패권 경쟁의 장이 되지 않도록 최선을 다해야 한다. 특히 우리는 강한 한・미 동맹을 근간으로 북핵 문제를 해결하고, 주변국과의 갈등 최소화 및 국익 극대화를 위해 그 어느 때보다 강한 국방력과 전략적인 사고로 자강(自强) 외교를 주도적으로 펼쳐야 한다. 핵심어: 러시아, 우크라이나, 한반도, 미국, 북대서양조약기구 □ 접수일: 2022년 3월 11일, 수정일: 2022년 3월 25일, 게재확정일: 2022년 4월 20일* 주저자, 제주대학교 교수(First Author, Professor, Jeju Univ., Email: speedynam64@naver.com)** 교신저자, 동아대학교 교수(Corresponding Author, Professor, Dong-A Univ., Email: strongleg77@gmail.com)