소아의 상완골 원위부 과간 골절

이우석,정환용,김우식,김용찬,전택수,김남현,김규태 대한골절학회 2004 대한골절학회지 Vol.17 No.4

상완골 원위부 과간 골절은 소아에서는 매우 드물게 발생되는 골절로 대부분 주관절의 굴곡상태로 주관절 후방부에 직접적인 충격에 의해 발생하는 것으로 보고되고 있다. 전위가 없거나 경미한 경우 도수적 정복술 혹은 도수적 정복술 후 경피적 핀고정술을 시행하며, 전위가 심한 골절이거나 도수적 정복술이 불가능한 경우 관혈적 정복술 후 핀고정술을 시행하는 것으로 알려져 있다. 저자들은 전위된 상완골 원위부 과간 골절 환아 2예에서 각각 도수적 정복술과 관혈적 정복술 후 K 강선 고정술을 시행하여 만족한 결과를 얻었기에 보고하는 바이다. Intercondylar fractures of the distal humerus are very rare in children. The pattern of the fracture would suggest that the mechanism of injury involves a fall directly on the flexed elbow. Most agree that the undisplaced fracture can be managed conservatively. With increasing displacement and comminution, the opinions tend to differ. We suggest that closed reduction with percutaneous K wire pinning and open reduction with percutaneous K wire pinning offer a satisfactory methods by which to treat displaced intercondylar fracture in children.

Ni-Cr-Mo-V鋼의 마르텐사이트 燒戾胞性에 미치는 溶體化處理의 영향

徐雨澤,趙完錫,趙顯麒 慶北大學校 産業開發硏究所 1985 硏究報告 Vol.13 No.-

The effect of solution treatment temperature on the tempered martensite embrittlement in 2.5% Ni-1% Cr-0.4% Mo-0.12% V steel has been investigated. Tempered martensite embrittlement occurs at 350℃ tempering. With increasing solution treatment temperature from 850℃ to 1,150℃, Charpy impact energy shows a maximum at 900℃ and decreases above/below 900℃. This seems to be attributed to the microsegregation of solute atoms below 900℃ and the growth of austenite grains above 900℃. The failure mode is primarily a cleavage fracture at the tempered martensite embrittlement temperature. With increasing solution treatment temperature, the amount of cleavage and the ductile to brittle transition temperature increase.

전해응집공정을 이용한 염색폐수의 처리

이용택,한승우,조영개,이현문,김태근,손인식,양병수 한국환경과학회 2000 한국환경과학회지 Vol.9 No.4

This research studied the characteristics and applicability of electrocoagulation using aluminium electrode for the color and COD removal in textile wastewater. Electrocoagulation reactor used two different electrode, Fe and Al, since in the general chemical wastewater treatment, aluminium and ferrous salts were used as coagulants. Aluminium electrode showed higher removal efficiency of color and COD than ferrous electrode did. The COD and color removal efficiency improved at the 0.192A/dm^2 current density. Thus, the electrocoagulation process with bipolar aluminium electrode showed better efficiency in the decolorization and COD removal rate of textile wastewater effluent than custom coagulants did.

당뇨병과 동반된 투명세포한관종 2예

박현호,우정택,이무형 대한당뇨병학회 2002 임상당뇨병 Vol.3 No.4

Clear cell syringoma has histologic characteristics of clear cells and is known to coexist with diabetes mellitus. Two patients visited our clinic due to asymptomatic skin colored papules around the eyelids. A 68-year-old woman had an increasing number of skin lesions which had initially developed 40 years previously. A 71-year-old woman had a skin lesion which had been found 1 year previously. On past medical history, they were diagnosed as having contracted diabetes mellitus 20 and 30 years previously, respectively.

쇄골 골절에서 지연성 상완 신경총 마비 : 1예 보고 A Case Report

이우석,정환용,전택수,김용상,김남현 대한골절학회 2003 대한골절학회지 Vol.16 No.2

상완 신경총 마비는 쇄골 골절 후에 매우 드물게 발생하며, 대부분 많은 가골 형성을 동반한 쇄골의 중간1/3 부위 골절 불유합에서 발생한다. 골절의 치유 과정에서 과형성된 가골이 상완 신경총을 압박할 수 있으며, 감압술고 불유합에 대한 수술적 치료를 필요로 한다. 이에 저자들은 쇄골 골절 후 불유합과 과도한 가골 형성에 의해 발생된 지연성 상완 신경총 마비 환자를 치험 하였기에 보고하는 바이다. The brachial plexus palsies secondary to nonunion of the clavicle fracture are extremely rare. The nonunions are hypertrophic and usually in the middle third of the clavicle. Hypertrophic callus produced healing process will cause a compression of the neurovascular bundle. This lesion requires operative treatment for decompression of the brachial plexus and internal fixation of nonunion. We present a case of delayed brachial plexus palsy due to nonunion and excessive callus formation of a clavicular fracture.

Bromocriptine 과 Cyproheptadine 이 Corticotropin-releasing Factor(CRF) 로 자극된 ACTH 분비에 미치는 효과

김진우,최영길,김영설,김광원,김선우,양인명,윤현구,우정택 대한내과학회 1986 대한내과학회지 Vol.31 No.5

Our study was desinged to observe the ACTH response to ovine CRF in healthy men and to observe the effect of bromocriptine or cyproheptine on ACTH and cortisol response induced by ovine CRF in healthy men. We have hypothesis that if hromocriptine or cyproheptatine inhibits the secretion of ACTH induced by ovine CRF, they decrease the secretion of ACTH in the pituitary level. The result were followings: 1) Plasma ACTH reached a peak of 1.5 and 1.6 times the basal level in response to ovine CRF at 10 min, and 30 min, respectively and decreased to the basal level at 90 min. 2) Cyproheptadine or bromocriptine did not inhibit the response of ACTH to ovine CRF. 3) We suggest that cyproheptadine or bromocriptine does not inhibit the ACTH secretion in the normal pituitary gland.

정상과 갑상선 종양조직에서 사람 IGF-I 유전자의 발현

김성운,장현하,박상미,김덕윤,우정택,양인명,김진우,김영설,김광원,고석환,홍성화,최영길 경희대학교 유전공학연구소 1993 遺傳工學論文集 Vol.5 No.-

Many of the growth-promoting properties of growth hormone(GH) are mediated by insulin-like growth factor-I(IGF-I), a highly conserved circulating 70-amino acid peptide. Recent studies have shown that multiple mechanisms influence IGF-I gene expression, including transcription from two promoters, alternative RNA splicing, and variable polyadenylation. In thyroid tissue, thyroid stimulating hormone(TSH) and IGF-I are the most possible candidates for follicular cell proliferation and hypertrophy. Actually IGF-I had autocrine and paracrine effect for tissue growing. We prepared thyroid tumor tissue mRNAs using single step method for detecting IGF-I levels according to different tissues, i.e., thyroid adenoma or papillary thyroid carcinoma. We used Northern blot analysis for IGF-I mRNA and RNase protection assay (RPA) for IGF-I transcription start sites. For Northern blot, we used whole human IGF-I cDNA as a DNA probe and for RPA, we used IGF-I exon 1 containing noncoding promoter 1 as a riboprobe. We got good RNA bands from Northern blot analysis around 1 kb (IGF-IA) and 7.5 kb (IGF-IB) region. To clarify the amount of both IGF-IA and IB mRNAs, we measured autoradiographied signal of IGF-I mRNAs bands using densitometer. In IGF-IA signals, there's no change among liver and thyroid tissues, but in case of IGF-IB mRNA bands, the signal was markedly increased in thyroid carcinoma tissues than that of normal thyroid tissue (85% vs 14%). In the study of RPA, all thyroid tissues used the same transcription start sites as those of liver's. We concluded that that this different regulation of IGF-I mRNA was originated from tissue specificity. That meant some tissue specific transcription factor/s were related to tissue IGF-I expression.

뇌실외 배액술 시행과 관련된 뇌실염 : 원인균주와 경험적 치료약제의 적절성

도병훈,김신우,오종택,손종원,하상우,이응갑,장현하,이종명,김능수 대한감염학회 2005 감염과 화학요법 Vol.37 No.2

목적 : 본 연구는 뇌실외 배액술을 시행한 신경외과 환자들에서 뇌실염 발생 빈도, 원인균주와 감수성 추이 및 경험적 치료로 사용되는 항생제인 ceftazidime과 vancomycin의 적절성 여부에 대하여 조사하였다. 재료 및 방법 : 2000년 12월부터 2003년 10월까지 EVD를 시행한 경북대학교병원 신경외과 입원환자 340명 중 뇌실염이 발생한 39명을 대상으로 후향적으로 조사하였다. 결과 : 340명 중 39예 (11.5%)에서 뇌실염이 발생하였고 이들 가운데 4명이 뇌실염과 연관하여 사망하였다(10.3%). EVD 시행일로부터 뇌실염 발생까지는 평균 8.4일이었다. 원인균은 33예(87.1%)에서 확인되었으며 Aci-netobacter (19예, 45%), methicillin-resistant coagulase negative Staphylococcus (9예, 22%), methicillin-resistant Staphylococcus aureus (9예, 22%) 등의 순이었다. 가장 많이 동정된 Acinetobacter 19예 중에서 8예(42.1%)가 ceftriaxone에 내성을 보였으며 현재 경험적으로 널리 사용되는 ceftazidime에 대해서는 11예중 3예(27%)가 내성을 보였다. 결론 : 최근 EVD 시행과 관련된 뇌실염 뇌실염 최근 그람음성 non-fermenter 특히 Acinetobacter에 의한 경우가 증가하고 있으며, 이들 그람음성 non-fermenter는 현재까지 경험적으로 사용되는 ceftazidime에 점차 내성을 보이고 있다. 경험적 치료제에 대한 성공률을 높이기 위해서는 각 병원별 내실염의 원인균주의 감수성에 대한 검사가 필요하겠다. Purpose : To investigate the etiologic microorganisms of external ventricular drain (EVD)-related ventriculitis and the appropriateness of using ceftazidime and vancomycin as an empiric therapy in neurosurgical patients with EVD-related ventriculitis. Materials and Methods : Retrospective analysis of 39 patients with EVD-related ventriculitis among 340 neurosurgical patients to whom EVD had been placed during December 2000 and October 2003 at Kyungpook National University Hospital. Results : Thirty-nine EVD-related infections (39/340, 11.5%) occurred and the attributable mortality rate was 10.3% (4/39). The average duration from the ventricular catheter placement to the development of ventriculitis was 8.4 days. All patients with EVD infection had fever and 89.7% (35/39) of the patients showed nuchal rigidity. The positive culture rate in CSF was 87.1% (34/39) and the frequency of individual organism is as follows : Acinetobacter 45% (19 cases), methicillin-resistant coagulase negative Staphylococcus 22% (9 cases), methicillin-resistant Staphylococcus aureus 22% (9 cases), Enterococcus 5% (2 cases), Streptococcus pneumoniae 3% (1 case), non-fermenting gram-negative bacilli 3% (1 case). The polymicrobial infection rate was 15.4% (6/39). Among 19 cases of Acinetobacter infection, 42.1% (8/19) of the strains showed resistance to ceftriaxone and 15.7% (3/11) to ceftazidime. However, all cases were sensitive to meropenem. Conclusion : These findings show that the major etiologic organisms causing EVD-related ventriculitis have recently changed to Gram-negative non-fermenters, especially Acinetobacter. Because Gram-negative non-fermenting rods resistant to ceftazidime are increasing, an immediate change from ceftazidime plus vancomycin, the widely accepted empiric antibiotic therapy, to meropenem plus vancomycin should be considered when clinical symptoms and signs show no improvement or even deterioration.

생활사건, 사회지지, 대처방식에 대한 전환장애와 신체화장애와의 비교연구

김승기,김현우,권택술 大韓神經精神醫學會 1991 신경정신의학 Vol.30 No.5

This study was designed to compare conversion disorder, somatization disorder patients to the matched controls about life events, social support, and coping skills. The number of subjects were 22 with conversion disorder, 21 with somatizaion disorder and 19 normal controls. Stress items. Interpersonal social-support assesement items, and The ways of coping checklist for clinical assesement were administered to all subjects to evaluate each relevant areas. In life events, conversion disorder patients and somatization disorder patients showed significantly hight moderate events than normal controls. In social support and coping skills, patients with conversion disorder or somazation disorder were significantly lower than controls. Conversion disorder showed to have less active coping but more passive coping than those with somatization disorder. Conversion disorder patients reported more life events than somatization disorder patients along with lacking in social support and coping skills. Somazation disorder patients showed much higher superior support-seeking score than conversion disorder patients. These differences may be considered to play some role in showing different clinical manifestations in the somazation disorder and conversion disorder.

Enhancement of Active Substance and Effect of Physiological Activity on Fermentation of Cudrania tricuspidata

Hyun-Woo Kim,Geon-Ung Jo,JI-Hyun Eo,Jong-Seok Park,Sang-Mi Kim,In-Taek Park,Deuk-Sil Oh,Song-Gui Oh 한국식품영양과학회 2017 한국식품영양과학회 학술대회발표집 Vol.2016 No.10