월경전기증후군의 심리적 요인에 관한 연구

이현제,최용성,권택술 大韓神經精神醫學會 1994 신경정신의학 Vol.33 No.2

Authors surveyed how the psychologic factors, especially the personality traits were related to the premenstrual syndrome, using PAF and MMPI, with 110 married nurses and 106 unmarried nursing students. The results were as follows : 1) There were no relations between the premenstrual syndrome and the demographic characteristics. 2) The high-scored types in PAF were turned out to be fatigue, lability, anxiety and atypical depressive features in rank order. On the contrary, the low-scored types in PAF were turned our to be increased well-being, hostility/anger, miscellaneous mood/behavior changes and impulsivity in rank order. 3) In the mean comparison of the MMPI scales among three clusters Pa, Pt and Sc scales showed statistically significant relations both in married and unmarried group, also D scale showed statistically significant relation in married group only and Hs, Ma scales showed statistically significant relation in unmarried group only. 4) In the mean comparison of the MPDS scales among three clusters BDL, ANT, CPS, PAG, PAR and STY scales showed statistically significant relations both in married and unmarried group, also DEP scale showed statistically significant relation in unmarried group only.

Chlorpromazine이 전기경련 충격에 의한 흰쥐 대뇌피질 c-fos 및 jun B 발현에 미치는 영향

강웅구,김용식,권택술 大韓神經精神醫學會 1995 신경정신의학 Vol.34 No.5

D₂ blockade is traditionally considered to be the major mechanism of action of antipsychotics But most antipsychotics have many other pharmacologic properties. This led us to investigate the mechanisms of action of antipsychotics from the viewpoint other than the blockade of D₂ We have chosen the induction of c-fos and jun B as a marker of the activity of brain cells and investigated the effect of chlorpromazine(CPZ) on the induction of c-fos and jun B by electroconvulsive shock(ECS) in rat cerebral cortex. CPZ did not affect the induction of c-fos and jun B by ECS at the dose of 10mg/kg. But at 30mg/kg, CPZ attenuated and retarded the induction of c-fos and jun B by ECS. Chronic treatment with CPZ(21 consecutive days, 10mg/kg/day) did not altered the patterns and peak amount of inductions. Considering D₂ blocking ability of CPZ, CPZ per se would induce c-fos and jun B or increase the induction of c-fos and jun B by ECS. But our results show the contrary. Hence, there seems to be other actions of CPZ than the blocking of D₂ receptor, such as the inhibition of calmodulin and protein kinases, on the signal transduction system of the brain.

장기간 혈액투석을 받는 말기 신부전환자의 정서상태 및 투석 순응도에 대한 연구

이준노,김창현,권택술 大韓神經精神醫學會 1995 신경정신의학 Vol.34 No.4

The purpose of this study is to evaluate the relationship between compliance of patients under hemodialysis and their affective states of depressed mood and anxiety. Subjects consist of 58 end-stage renal failure patients on the long-term hemodialysis of one year or longer. Depressed state was evaluated with Beck Depression Inventery(BDI) and anxiety state was assessed with Self-rating Antiety Scale(SAS). The compliance in terms of diet, medication and fluid was assessed with Potassium(K), Phosphorus(P) and Interdialytic Weight Gain(IWG), respectively. the primary findings are as noted below. 1) 58.6% of the subjects felt depressed, but anxiety level was quite within normal range. 2) There were no intercorrelations between the compliance parameters of diet, education and fluid intake. preliminary correlations are as follows. The level of depression correlated with that of anxiety. Educational level is correlated negatively with scores of depression and anxiety. Duration of marriage is correlated positively with scores of depression. 3) Only anxiety, not depression, correlated with IWG, when controlled for age, sex and other clinical variables. But, anxiety did not correlate with K and P. This result may suggest that IWG is a more sensitive indicator of compliance than K and P.

생활사건, 사회지지, 대처방식에 대한 전환장애와 신체화장애와의 비교연구

김승기,김현우,권택술 大韓神經精神醫學會 1991 신경정신의학 Vol.30 No.5

This study was designed to compare conversion disorder, somatization disorder patients to the matched controls about life events, social support, and coping skills. The number of subjects were 22 with conversion disorder, 21 with somatizaion disorder and 19 normal controls. Stress items. Interpersonal social-support assesement items, and The ways of coping checklist for clinical assesement were administered to all subjects to evaluate each relevant areas. In life events, conversion disorder patients and somatization disorder patients showed significantly hight moderate events than normal controls. In social support and coping skills, patients with conversion disorder or somazation disorder were significantly lower than controls. Conversion disorder showed to have less active coping but more passive coping than those with somatization disorder. Conversion disorder patients reported more life events than somatization disorder patients along with lacking in social support and coping skills. Somazation disorder patients showed much higher superior support-seeking score than conversion disorder patients. These differences may be considered to play some role in showing different clinical manifestations in the somazation disorder and conversion disorder.

응급실 내원 정신과 환자의 1979년과 1989년 비교

김현우,권택술,김홍환 大韓神經精神醫學會 1990 신경정신의학 Vol.29 No.6

The purpose of this report is to compare the characteristics of emergency patients visiting the emergency room during 1979 and 1989. The authors compared a total 110 psychiatric patients who visited the emergency room of the National Medical Center during one year beginning on January 1, 1979 with a total of 368 psychiatric patients who visited the same emergency room during one year beginning on January 1, 1989, and we came to the following results. 1. The changed aspects from a statistical point of view were: 1) Total number of patients was more than doubled, and the number of all psychiatric patients was nearly doubled. 2) More patients visited the emergency room at night rather than in the day. 3) There was an increase of male patients in their thirties and a decrease of male patients in their twenties. 4) There was diagnosis of a tendency towards a decline in organic brain syndrome and a tendency towards an increase in personality disorder. 5) Less patients were admitted and more patients were transfered either to the other depantment or to the closed ward. 2. The distribution according to sex, residential area, season and symptom was not changed. Female patient age distribution was unchanged. The proportion of neurotic disorder and that of psychotic disorder remained same. The rate of referral for out-patient treatment was unchanged.

폐쇄성 수면 무호흡-저호흡 증후군 환자의 자기공명검사를 이용한 상기도 분석

윤진영,주은연,김선화,조재욱,이지현,김성태,권택술,김형진,홍승봉 대한신경과학회 2007 대한신경과학회지 Vol.25 No.3

Background: To investigate the upper airway changes in obstructive sleep apnea-hypopnea syndrome (OSAHS) patients, we measured cross-sectional areas of the upper airway [retropalatine (RP) and restoglossal (RG) regions] and volumes of upper airway structures on upper airway MRI in OSAHS patients and normal controls. Methods: The Apnea/Hypopnea index (AHI) of OSAHS patients was calculated by overnight polysomnography whereas apnea-hypopnea screening for normal controls was performed by a portable screening device. Upper airway MR images were obtained in normal subjects and OSAHS patients using a 1.5-T MRI scanner. The following parameters were measured on MRI using Analyze 6.0 software: (1) mean area, minimal area, vertical and horizontal lengths of the minimal area in RP and RG region; (2) volumes of RP and RG airway, soft palate, lateral pharyngeal wall, lateral pharyngeal fat pad and tongue. Results: Nineteen OSAHS patients and 14 normal controls were included. Body mass index (BMI) and AHI were significantly higher in OSAS (BMI 27.7±2.5, AHI 56.8±22.3) than normal controls (BMI 23.0±1.9, AHI 3.5±2.1). OSAHS group had significantly smaller mean RP and RG area, smallest area in RP and RG regions and horizontal length of smallest area in RP and RG regions. The volumes of soft palate and lateral pharyngeal wall were larger in the OSAHS group. Conclusions: Korean OSAHS patients had smaller mean RP and RG area, minimal RP and RG area and horizontal length in minimal RP and RG region and larger volume of soft palate and lateral pharyngeal wall than normal controls.