間歇的 運動에 의한 脫水 및 水分攝取의 生理的 效果

朴哲浩,朴吉俊,李相于,金永明,朴贊熙,玄松子,呂南會,朴相甲,金榮俊 東亞大學校附設스포츠科學硏究所 1989 스포츠科學硏究論文集 Vol.7 No.-

This study aims at revealing the physiological responses of dehydration (DH) and rehydration (RH) in intermittent exercises at the work intensity of 70% HR max. First, with general student public, three times of exercise (each for 20 minutes) at the given work intensity were taken, with a break for 25 minutes respectively. Their heart rate, rectal temperature and plasma electrolyte concentration both DH and RH were measured. Second, in two groups of athletes and non-athletes, 9 rounds of exercise (for 100 minutes) and 8 breaks (for 60 minutes) were taken, with RH forced 10 times to compensate for the subjects' water loss. Their change in sweat loss and plasma electrolyte concentration as well as the IVDP(Intensive Voluntary dehydration Phenomenon) were experimented. The summary of this research follows. 1) Mean heart rate and rectal temperature in intermittent exercises were higher at DH than at RH, growing up at the increasing level of DH. 2) RH saw no change in the plasma concentration of Na+, K+ and Cl-, while DH observed a significant increase. 3) HCO₃made a significant decrease at DH before growing up. 4) Mg++ had no change, while Ca++ increased significantly at RH and DH. 5) Lactate showed an increase with significance at RH and DH, especially greater at DH. 6) Osmotic pressure increased meaningfully at DH. 7) Anion gap increased significantly at DH and RH. 8) On the other hand, when the forced RH was held, the group of athletes had greater sweat loss per body surface area than that of non-athletes. 9) The athletes' plasma concentration of Na+ and Cl- revealed a clear decrease. 10) There was seen no significant change in the plasma concentration of K+, Mg++ and Ca++ in both groups. 11) The IVDP occurred at the RH of 2.3ℓfor athletes and more than 2.5ℓfor no-athletes.

흰쥐 Kupffer 세포에 대한 Propofol의 작용

박세훈,지대림,성언기,김희선,송인환,박희영,김준수,이덕희,박대팔 대한마취과학회 2002 Korean Journal of Anesthesiology Vol.43 No.4

Background: Propofol has an antioxidant capacity and can be used for ischemia-reperfusion injury of the liver. However, the effects of propofol on the Kupffer cells have not been establisked. Methods: Kupffer cells were isolated and cultured from male Sprague-Dawley rats. The effects of propofol on the Kupffer cells were evaluated by a phagocytosis assay, TNF-α gene expression, and superoxide anion release after administering propofol in different concentrations on the cultured Kuprrer cells. Results: The latex bead phagocytosis by the Kupffer cells was suppressed when the Kupffer cells were exposed to propofol irrespective of concentrations. Higher propofol concentrations decreased the loss of Kupffer cells after latex bead phagocytosis. Propofol induced TNF-α mRNA expression in the Kupffer cells, but the mRNA expression level after 50㎍/ml of propofol decreased. The pattern of TNF-α mRNA expression induced by propofol was different to that induced by LPS: TNF-α mRNA was expressed continuously in the propofol-treated cells until 16 hours after exposure to propofol, whereas the level of TNF-α mRNA expression induced by LPS was evident after 2 hours and was not found thereafter. TNF-α production after propofol treatment was not higher than that of the control. Formazan presipitation did not show any qualitative differences between cells untreated or treated with propofol concentrations of 0.5, 5.0, and 50 ㎍/ml. Conclusions: These results showed that propofol might inhibit Kupffer cells. This suggests that propofol and be used for patients with ischemia-reperfusion injury of the liver. (Korean J Anesthesiol 2002; 43: 475~484)

급성 심근허혈에 의해 윤발된 승모판 폐쇄부전의 기전에 관한 실험적 연구

강덕현,송현,송재관,김현숙,이재환,임희영,이재원,박성욱,박승정,송명근 대한순환기학회 1999 Korean Circulation Journal Vol.29 No.8

도시공원에 있어서 공원적 수목원 조성 방안에 관한 연구 : 목포시 유달산 도시자연공원을 사례지역으로 A Case for Urban Natural Park of Yudal-San in Mokpo City

조영환,우창호,곽행구,박송희 木浦大學校 沿岸環境硏究所 1996 沿岸環境硏究 Vol.13 No.1

This study aims is suggested a development methods of reasonable for security to identity of urban park which supplement to demerits of urban natural park and arboretum. Park orinted arboretum had characteristic not only enjoyment but learned to use all facility of park and exhibition at the same time to function of scientific research, education and park. Case study is conducted on the YU DAL SAN in Mok po city.

조혈모세포이식을 받은 급성 골수 백혈병 환자에서 발생한 cyclosporine에 의한 양측 시신경병증

정진권,김한조,박명진,하승주,최경식,이성진,박성희,이상철,이남수,박희숙,원종호 순천향대학교 의학연구소 2007 Journal of Soonchunhyang Medical Science Vol.13 No.2

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기름골의 품질관련 특성 평가 : Cyperus esculentus L., var sativus Boeck

송진,방진기,박희운,이승은,박남규 한국국제농업개발학회 2002 韓國國際農業開發學會誌 Vol.14 No.4

기름골의 일반적인 이화학성분과 기름을 추출하여 기름의 특성을 평가한 결과를 요약하면 다음과 같다. 1. 기름골의 일반성분 중 조지방과 조섬유의 함량은 각각 22.4%, 13.3%이고, 총 아미노산 함량은 6,882.4㎎%로 cystein과 isoleucine의 함량이 1,572㎎%, 905㎎%로 가장 높았다. 2. 기름골 전분의 아밀로스 함량은 46.9%였고, RNA 측정결과 최대, 최저 및 최종점도는 각각 451, 280 및 375RNA였다. 3. 기름골 기름의 산가와 과산화물가는 2.1, 6.2meq/㎏이며 지방산 함량은 oleic acid가 70%를 차지하였다. 4. 기름골 기름의 토코페롤 측정결과 α, β, γ, δ가 모두 검출되었고, 그 중 α-tocopherol이 약 15㎎%로 가장 많이 함유되었다. 5. GC/MS를 이용하여 향기성분을 분석한 결과 주된 향기성분은 2.5dimethyl pyrazine으로 약30%를 차지하였다. The objective of this study were to evaluate quality characteristics of the chufa tuber and its oil. The results are summarized as follows : Crude fat, crude fiber and total amino acid were 22.4%, 13.3% and 6.882㎎% of the chufa tuber, respectively. Amylose content of chufa starch was 46.9% and maxium. Minimum and final viscosity of amylogram characteristics in chufa starch were 451, 280 and 375 RVA, respectively. The acid value of oil was 2.1 and peroxide value was 6.2meq/㎏. The content of oleic acid, a major fatty acid in chufa oil, was 70%. Four type of tocopherol were detected and α-tocopheral was shown to be the major tocopherol. The volatile component was measured by GC/MS. 2.5-Dimethyl pyrazine was the dominant volatile component in the whole chufa oil.

갑상선 유두선암 환자의 말초 혈액 단핵구로부터 수지상세포분화와 자가 세포독성 T 림프구 활성화 유도

송수근,최영식,박요한,이대희,장희경 고신대학교 의학부 2004 高神大學校 醫學部 論文集 Vol.19 No.1

Background: Dendritic cells (DCs) are rare leucocytes that are uniquely potent in their ability to capture, process and present antigens to T cells, and so selectively migrate through tissues to reach lymph nodes and spleen where initiation of immune responses takes place. It has been reported that a dense infilteration of dendritic cells correlates with a favorable prognosis in several types of cancer. A similar correlation also has been noted in patients with papillary carcinoma of thyroid. The purpose of this study is to determine whether DCs are generated from peripheral blood monocytes by using cytokines such as GM-CSF, TNF-α, and IL-4 and whether cytotoxic T cells activated by DCs attack the papillary carcinoma tissues. Methods: Peripheral blood was obtained from 2 patients with thyroid papillary cancer. DCs were established from monocytes by culturing in the presence of GM-CSF, Flt-3 ligand. TNF-α , and IL-4 for14 days. At day 14, expression of surface markers typical for DCs was analyzed morphologically. The immunophenotypic features of DCs such as CDla, CD83, and CD86 were analyzed by phase contrast microscopy. At day 15 DCs were incubated with thyroid cancer tissues and normal thyroid tissues for 7 days. Results: DCs were generated from the peripheral blood monocytes. The generated cells had the classic morphology of DCs. Activated cytotoxic T lymphocytes (CTLs) were observed. Veiled cell known as circulating DCs attached to the thyroid cancer tissues were observed. The CTLs activated by DCs were observed to attack the papillary carcinoma tissues by scanning electron microscope. However, normal tissues were not attacked by CTLs. Conclusion: DCs can be generated from the peripheral blood monocytes. Futhermore, the CTLs activated by DCs also can attack the papillary carcinoma tissues. These results that DCs can be used as adjuvants for adoptive immunotherapy of papillary thyroid cancer.

경동맥 내막 절제술 후 발생한 과관류 증후군 1예

송희정,박광열,정진상,조수진,이순정,허승,김동익,이광호,이병붕 대한신경과학회 1999 대한신경과학회지 Vol.17 No.2

Osteotome Sinus Floor Elevation Procedure를 이용한 임프란트 매식

송종운,조용기,박홍주,김영운,오희균,유선열 대한악안면성형재건외과학회 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.2

Maxillary sinus has an anatomic limitation to bone support available for dental implant. When there is less than 10㎜ of bone remaining between the upper alveolar ridge crest and the maxillary sinus floor, bone augmentation should be considered. In 1994, Summers reported two sinus floor elevation techniques of limmediate implant insertion, using osteotomes, for patients who have at least 5㎜ of bone remaining between the alveolar ridge crest and the maxillary sinus floor. One technique is osteotome sinus floor elevation (OSFE) procedure in which uses osteotomes to elevate the sinus floor. The other is bone-added OSFE (BAOSFE) procedure in which bone graft is added into osteotomy site. Both procedures conserve all of the remaining bone and selectively displace it upward, thereby raising sinus floor. This study was aimed to evaluate the long-term success rate of implants which had been placed by osteotome sinus floor elevation procedure. Between February 1996 and June 1998, 10 implants were placed using OSFE or BAOSFE procedures in 6 patients who had at least 6㎜ of bone remaining between the alveolar ridge crest and the sinus floor. OSFE procedures were performed in patiens, 2∼4㎜ sinus floor elevation was needed, whereas BAOSFE procedures were done in patines, more than 4㎜ sinus floor elevation was needed. During the mean follow-up period of 4 years 4 months (3 years 6 months ∼ 5 years 9 months), no implant was failed and all patients showed good functional results. OSFE and BAOSFE procedures seemed technically easier and less invasive compared to conventional sinus lift procedure. And both procedure have good success rate.

해조류를 이용한 항생재 대체 사료 첨가제 개발

박진용,김진욱,이희현,이송애,김진욱,이재화 신라대학교 자연과학연구소 2005 自然科學論文集 Vol.14 No.-

우리나라의 항생제 남용 문제는 세계적으로 심각 하다고 한다. 이러한 문제를 해결하기 위해서 정부는 다양한 정책을 도입하고 있으며 특히 축산물의 항생제 남용 문제를 해결하기위해 사료 관리법을 강화하여 항생제 사용을 억제하고 있어 항생제를 대체 할 물질이 필요하다. 이런 문제를 해결하기 위해서 우리나라의 다양한 해조류를 이용한 항생제 개발을 통해서 항생제 남용 문제를 해결하고 소비자들에게 믿을 수 있는 축산물을 제공 할 것으로 보인다. Feed official law was strengthened recently. The antibiotic use is suppressed with feed official law reinforcement. The antibiotic transfer material is necessary. To use the seaweeds and transfer the antibiotic. It is a possibility of a high income. This is new bio industry. This the goods production which is competitive power is possible. It is a possibility of eating the livestock where also the consumers are good.