강남경희한방병원에 내원한 냉증을 호소하는 여성의 Heart Rate Variability 특성 연구

이미주 ( Mi Joo Lee ),김은경 ( Eun Kyung Kim ),이진무 ( Jin Moo Lee ),조정훈 ( Jung Hoon Cho ),장준복 ( Jun Bock Jang ),이경섭 ( Kyung Sub Lee ),이창훈 ( Chang Hoon Lee ) 대한한방부인과학회 2011 大韓韓方婦人科學會誌 Vol.24 No.3

울형성 심부전증에서 심혈관계 보상기전의 지표로서 저나트륨혈증의 의의에 관한 연구

김경환,김미경,이우형,홍사석,신길자,장일중 대한내과학회 1986 대한내과학회지 Vol.31 No.3

In patient with congestive heart failure, it is well known that the sympatho-adrenal system and the renin angiotensin system are activated to compensate for the reduction of cardiac output and the redistribution of blood flow. Although Lilly, et al. (1984) and Francis, et al. (1985) have insisted that the induction of these circulatory compensation mechanism by pastura1 changes is closely related to the concentration of plama sodium in congestive heart failure, it is still controversial. Thus, in an effort to clarify this hypothesis, present study was designed to determine the relationship between the existing sodium concentration in plasma and the changes of the plasma catecholamine concentration and renin activity during postural alterations in patients with congestive heart fai1ure and normal subjects. Ten patients with congestive heart failure who had been admitted to the Ewha Womans University Hospital from May, 1985 to July, 1985 and five normal volunteers were chosen. Patients with more than one year history of congestive heart failure belonging to class 3 or 4 as the criteria set by the New York Heart Association have been selected for this study. Among these ten patients, 5(3 males and 2 females) had low plasma sodium concentration(below 135mEq/l) and 5(3 males and 2 females) had normal plasma sodium concentration(above 135mEq/l). The observed results are as follows: 1) In the normal subjects, the observed plasma renin activity was 1,2±0.4ng/ml/hr and the concentrations of norepinephrine and epinephrine were 177.5±27 and 150.0±8pg/ml, respectively, at supine position. However, these values were increased by about 2 times by changing to upright position. 2) In patients with hyponatremic congestive heart failure, the values of plasma renin activity and catecholamine levels were significantly higher than those patients having normonatremia. 3) The increase in the plasma renin activity and catecholamin levels induced by upright position were minimal in patients with congestive heart failure having normonatremia. 4) However, in patients with hyponatremic congestive heart failure, the plasma renin activity and the levels of plasma catecholamines were not altered, or rather decreased, by the same postural changes. Based on the results, the levels of plasma sodium concentration in patients with congestive heart failure could provide an index for the induction of circulatory compensation mechaniams and may have important significance in determining the severity and prognosis of the disease. Particularly in the congestive heart failure patients with hyponatremia, as the circulatory compensation mechanism appear to be operating at maximum already, they would not be able to utilize the reflex compensation mechanism inducible with the changes of body position.

八味元이 Streptozotocin 糖尿病에 미치는 影響

김희경,문정숙,박귀영,이다미,이은영,장윤경,황미경 曉星女子大學校 藥學大學 學生會 1988 曉星藥誌 Vol.4 No.-

Streptozotocin was injected to rats and rabbits to induce the experimental diabetes mellitus and Palmiwon was administrated to observe the changes of blood sugar, body weight, and serum Zn, Ca, Mg level in order to find out the effect of diabetic tratment by experimental method. And thus, the result was as follows: 1. The blood sugar level of diabetic rat was decreased after administration of Palmiwon. 2. Body weight of diabetic rat was moderately decreased after administratin of Palmiwon. 3. The less streptozotocin, 30 mg/kg, don't easily induce diabetes mellitus in rabbits. We did not find the changes of blood sugar, serum Zn, Ca, Mg level in the rabbits injected by streptozotocin, 30mg/kg of body weight.

Increased Neutrophil Extracellular Trap Formation in Uremia Is Associated with Chronic Inflammation and Prevalent Coronary Artery Disease

Kim, Jwa-Kyung,Hong, Chang-won,Park, Mi Jin,Song, Young Rim,Kim, Hyung Jik,Kim, Sung Gyun Hindawi 2017 Journal of immunology research Vol.2017 No.-

<P><I>Background.</I> Neutrophils are involved in the pathogenesis of atherosclerosis by neutrophil extracellular trap (NET) formation. We hypothesized that the NET formation of neutrophils might be changed in end-stage renal disease (ESRD) patients, explaining their higher incidence of coronary artery diseases (CAD). <I>Method.</I> A cross-sectional study was performed in 60 maintenance hemodialysis (MHD) patients, 30 age- and sex-matched healthy individuals (HV, negative control), and 30 patients with acute infection (positive control). Neutrophil activation and function were measured with reactive oxygen species (ROS) activity, degranulation, NET formation, and phenotypical changes. <I>Result.</I> Compared with HV, neutrophils extracted from MHD patients displayed significantly increased levels of basal NET formation, ROS production, and degranulation, suggesting spontaneous activation in uremia. Also, an increase in citrullinated histone H3 was detected in this group compared to the HV. And neutrophils from HV were normal CD16<SUP>bright</SUP>/CD62L<SUP>bright</SUP> cells; however, neutrophils from MHD were CD16<SUP>bright</SUP>/CD62L<SUP>dim</SUP>, similar to those from patients with acute infections. Interestingly, multivariate analyses identified the prevalent CAD and neutrophil counts as independent determinants of baseline NET formation (<I>β</I> = 0.323, <I>p</I> = 0.016 and <I>β</I> = 0.369, <I>p</I> = 0.006, resp.). <I>Conclusions.</I> Uremia-associated-increased NET formation may be a sign of increased burden of atherosclerosis.</P>

교양수업 참여 대학생의 라이프스킬 학습과 전이를 위한 PEAK 프로그램의 효과

양윤경 ( Yang Yun-kyung ),임태희 ( Lim Tae-hee ),이창민 ( Lee Chang-min ),윤미선 ( Yun Mi-seon ),배준수 ( Bae Jun-su ) 국기원 2021 국기원태권도연구 Vol.12 No.1

목적 이 연구의 목적은 교양수업에 참여하는 대학생을 대상으로 태권도와 라이프스킬을 통합한 PEAK 프로그램을 적용하고 라이프스킬 학습 및 전이의 변화를 확인하는 것이었다. 방법 연구참여자는 Y대학에서 교양수업을 수강하는 대학생 25명(남자 14, 여자 11)을 목적적 표집방법으로 선정했다. PEAK는 매주 1회 120분씩(태권도 수련 90분, 워크시트 30분) 15주에 걸쳐 적용했다. 자료는 스포츠라이프스킬과 전이 측정도구를 사용하여 수집했고, 변화내용을 구체적으로 살펴보기 위해 심층면담을 진행했다. 수집된 자료 중 양적자료는 사전-사후 점수차이를 비교하기 위해 대응 t-test와 Cohen의 효과크기(d )를 계산했다. 질적자료는 전문가 협의를 통해 분석·검토하여 양적결과를 뒷받침하는 사례를 도출했다. 결과 사전점수와 사후점수를 비교한 결과 라이프스킬과 전이의 몇 가지 하위요인에서 통계적으로 유의한 효과가 있었다. 구체적으로 라이프스킬 하위요인에서는 목표설정과 시간관리의 효과크기가 통계적으로 유의했다. 전이에서는 친구갈등해결, 목표설정, 만나기와 인사하기, 그리고 도움주고받기의 효과크기가 통계적으로 유의했다. 심층면담 결과에서는 통계적으로 유의한 변화가 나타난 요인들에 대해 학생들의 구체적인 사례를 제시했다. 결론 PEAK는 대학생의 라이프스킬 학습과 전이에 부분적으로 유의한 효과를 미친다. 이 연구의 결과는 유소년에게만 국한되어 있던 라이프스킬 교육을 다양한 연령층으로 확대하는 데 도움을 줄 수 있을 것으로 기대한다. Purpose The purpose of this study was to apply the PEAK (Performance·Enhancement·Achievement·Knowledge) program, which integrated Taekwondo and life skills, to college students and to identify changes in life skills and transfer. Method 25 (male=14 and female=11) students taking general education classes at Y university were selected as the participants by using the purposive sampling method. The PEAK was applied once a week for 120 minutes (90 minutes taekwondo, 30 minutes worksheet) for 15 weeks. Data were collected using the sport life skills scale and transfer survey. Also, in-depth interviews were conducted to examine the details of the changes. Quantitative data were conducted corresponding paired t-test to compare the differences in pre- and post-scores, and the Cohen’s effect size (d) was calculated. Qualitative data were analyzed and reviewed through the expert meeting to derive meaningful results. Results Comparison of pre- and post-score results showed statistically significant effects in several sub-factors of life skills and transfer. Specifically, the goal setting and time management sub-factors of life skills were statistically significant with Cohen’s d effect sizes. The effect sizes of friend conflict resolution, goal setting, meeting and greeting, and helping each other in the life skills transfer were statistically significant. The results of the in-depth interview provide specific examples of students for factors that show statistically significant changes. Conclusion The PEAK had a partially significant effect on the life skills development and transfer of college students. The findings of this study are expected to help expand life skills education, which was limited to youth, to various age groups.

Hydroxycitrate, Carnitine 및 Capsaicin을 함유한 식이 보조제(3D-Relax Diet)의 체중 감량 효과

정은영,정경희,김미자,배윤정,장은재 동덕여자대학교 2004 생활과학연구 Vol.9 No.-

The aim of this study was to evaluate the effects of 3D-Relax Diet; a proprietary formation containing hydroxycitrate(233mg/g), carnitine(150mg/g); and capsaicin (150mg/g); on body weight, % body fat, fat mass, lean body mass, Resting Metabolic Rate(RMR), body circumference, skinfold thickness, serum glucose and lipid level. Nineteen female college students participated in this 4 weeks weight control program. All subjects were randomly assigned to the Sang sik(S) group or Sang sik & 3D-Relax(3D) group. Mean energy intake of 3D group was l,523.1±300.2 ㎉(carbohydrate: 66.3%, protein: 18.7%, fat: 15.0%) and S group consumed 1,464.8±142.1 ㎉(carbohydrate: 65.1%, protein: 19.0%, fat: 15.9%) during program. The 3D group lost 3.1±1.3 kg of body weight, 2.5±l.4 kg of fat mass, 0.6±1.2 kg of lean body mass and 16.8±183.3 ㎉/d of RMR and the S group lost 1.8±1.0 kg of body weight, 1.1±1.1 kg of fat mass, 0.8±0.3 kg of lean body mass and 19.1±181.9 ㎉/d of RMR. There was no significant differences in the loss of lean body mass and RMR between two groups, however, the total body weight and the fat mass were significantly decreased in the 3D group compared to the S group(p<0.05). The 3D group experienced a significant reduced hip size, total-cholesterol and HDL-cholesterol, however, the change of these between groups were not significantly different. There were no differences in the change of body circumference, skinfold thickness, serum glucose and lipid. These results suggest that the intake of 3D-Relax Diet(hydroxycitrate, carnitine, and capsaicin) during the weight control program decreased energy intake, fat intake and total body weight especially fat mass and those effects are presumably linked to the prevention of RMR decline and the inhibitory effects on lipogenesis.

국내산 중하(Metapenaeus joyneri) 내 주알레르겐 규명 : 가열 및 소화액에 의한 변화

윤성호,김현아,김현미,최정희,서창희,남동호,김윤근,민경업,박해심 대한알레르기학회 2004 천식 및 알레르기 Vol.24 No.2

大豆栽培의 省力化를 爲한 除草劑의 效果

張權烈,韓鏡秀,高美錫,崔震龍 慶尙大學校 1972 論文集 Vol.11 No.-

以上의 結果를 要約하면 아래와 같다. 1. 雜草發生率은 品種間에는 有意性이 없으며 약제간에는 Mon가 7%, Lark 31%, MA 32%로서 Mon가 雜草發生이 제일 낮았다. 2. 雜草重은 品種間에는 有意性이 없으며 약제간에는 Mon 12.5kg, LA 13.7kg, MA 15kg로서 Mon가 제일 적었다. 3. 除草劑의 처리에 의한 種實重量은 관행구에 비하여 Mon은 56.8%, MA는 55.9%가 감소 되었고 LA는 가장 낮은 46.7%가 감소 되었다. 4. 經濟性 分析의 結果 10a當 순수익으로 LA 3,463원 MA 2,736원 Mon 2,641원으로서 관행구의 868원에 비하여 除草劑의 처리에 의하여 순수익을 높일 수 있었으므로 除草劑의 導入이 時急하다. The objective of this study was to evaluate the three herbicides, Machete, Mon-097 EC, and Lasso for annual weed control in soybeans at the experimental farm of Gyeong-Sang College. The results were summarized as follows; 1. The ratio of weed was not shown significance among the varietieties, as shown Tables 1 and 2, but the significance was shown among the herbicides and the plot of Mon-097 herbicide showed lowest value, 7%, as shown in Table 1. 2. The weight of weed also was not shown the significance among the varieties but the significance was shown among the herbicides, such as shown in Tables 1 and 2. The weight of weed also showed the same tendency as the ratio of weeds. 3. The yields of treated soybeans showed lower yield than normal condition plot, such as Mon-51.8%, Ma-55.9%, La-46.7%, respectively. 4. According to the analysis of economic values, herbicide plots were got more net-income than normal condition plot. It is needless to say that herbicides had to be recommendable in this case.

병원의 정보화에 따른 의료정보교육의 방향

장창곡,배미경 한국보건정보교육학회 2000 보건정보교육학회지 Vol.2 No.1

The purpose of this study was to provide a curriculum for the education of medical record technician in school according to the computerization of hospital. The data used in this study were collected between 26 July 1999 and 7 September 1999 from the department of medical record of 44 tertiary hospitals in Korea using questionnaire. The results were as follows; 1) more than 70.0% of hospital were computerized but not sufficient to the needs of department of medical record. 3) most of the hospitals wanted the medical record technicians have qualified with medical informatics, specifically, information retrieval, statistical package, database, spread sheet, word processing, access and approach, power point, and windows. 4) the most important subjects in the education of medical record technicians were medical terminology, chart review, classification of disease and quality assurance. According to the above results a possible curriculum was developed. This model of curriculum can be devided as the field of medical record and medical informatics and the contents can be consisted of several areas such as biomedical science, health care delivery system, health data and structure, information technology, health care statistics analysis and research, clinical quality assessment and performance improvement and medical insurance and legal affairs in medical care.

大豆雜種初期世代의 收量에 대한 經路係數 分析

張權烈,高美錫,韓鏡秀,金鎭馨 慶尙大學校 1986 論文集 Vol.25 No.2

大豆 新品種育成의 重要性에 비추어 選拔에 대한 基礎資料를 얻고자, 6個品種을 二面交雜하고 이들에서 얻은 15個組合 雜種 F1 및 F2世代를 材料로 經路係數를 分析하여 各量的 形質들이 收量에 미치는 直接 果와 形質相互間의 間接 果를 算出한바, 그 結果는 다음과 같았다. 1. 各形質들의 收量에 미치는 直接 果는 世代間에 多少의 差異는 있었지만, 株當莢數, 莖直徑, 莖長, 成熟口數 및 100粒重等이 크게 評價되었다. 2. 形質間의 間接 果는, 株當莢數가 全組合間에 큰 影響을 미쳤으나 100粒重은 成熟日數, 分枝數로부터 받는 間接的 影響이 더 컸었다. 3. 株當莢數가 收量에 미치는 影響은 直接 果가 支配的이었으나 莖長, 莖直徑 및 生育日數로부터 間接的 影響을 받음으로써 그 果는 더욱더 컸을 것으로 推定되었다. A set of 15 crosses of F1's and F2's from six soybean varieties (Danyeopkong, D70-7485, Ilyangjidu, Yukoo#3, Gungnae Jungsaengjidu and Ganglim) were grown in the field to estmiate the path-coefficient for direct and indirect effects of each character influencing grain yield. From a serious of experiments conduced in 1981 to 1982, nine agronomic characters, i.e., days to flowering, days from flowering to maturity, days to maturity, stem length, stem diameter, branch numbers per plant, pod numbers per plant, 100-grain weight and grain weight per plot(grain yield) were observed. By means of a path-coefficient analysis method, the yield of soybean was found to be mainly associated with the characters such as pod numbers per plant, stem length, stem diameter and the highest affectable character to grain yield was pod numbers per plant. The direct effect of 100-grain weight to yield was found to be lower than the indirect effect of other characters.