가감청영탕(加減淸營湯)에 효과를 보인 열성 아토피 피부염 환자 6례 증례 보고

서지혜,정창환,박선정,임소영,한수련,Seo, Ji-Hye,Jung, Chang?Hwan,Park, Seon-Jeong,Lim, So-Young,Han, Su-Ryun 대한한방안이비인후피부과학회 2014 한방안이비인후피부과학회지 Vol.27 No.3

Objective : The purpose of this study is to investigate the effect of Gagamchengyoung-tang($Ji\bar{a}ji\check{a}nq\bar{i}ngy\acute{i}ng-t\bar{a}ng$) for atopic dermatitis patients diagnosed as the febrile tendency. Method : This case study was done on 6 atopic patients with febrile tendency who have visited Korean Medicine Clinic from 2013.08.01. to 2014.04.30.. Gagamchengyoung-tang($Ji\bar{a}ji\check{a}nq\bar{i}ngy\acute{i}ng-t\bar{a}ng$) was prescribed to all 6 patients and evaluated the symptom change through photographs and questionnaire. Objective SCORAD Index(OSI) was used to evaluate the objective symptom and VAS was used to evaluate the subjective change. Results & Conclusion : The Objective SCORAD index and VAS were decreased in all patients. The average OSI reduction score was 26.3. Most symptoms of 6 patients were improved. Gagamchengyoung-tang ($Ji\bar{a}ji\check{a}nq\bar{i}ngy\acute{i}ng-t\bar{a}ng$) can be effective in patients who were diagnosed as febrile tendency.

Production and Characterization of Enzymes Involved in Chitin Catabolic Cascade from a Bacterial Strain Isolated from Soil

( Ji Hyun Lee ),( Jeong In Lee ),( So Yeon Park ),( Yoo Kyeong Jang ),( You Bin Lim ),( Hye Yoon Lee ),( Young Min Jung ),( Hae Chang Lee ),( Jong Hwa Lee ),( Shaheen Amna ),( Jae Kweon Park ) 한국키틴키토산학회 2019 한국키틴키토산학회지 Vol.24 No.1

The present study was aimed to isolate the bacteria producing chitinolytic enzymes including chitin deacetylase (CDA) from soil origin. About 24 bacteria were screened for their chitinolytic enzymes producing ability on the basis of colloidal chitin. Amongst one of the most potent isolates designated to JI-02 was further selected as the most prominent chitinolytic and CDAlike enzyme (CDA-X) producer based on the ability of deacetylation of an artificial substrate pNP-acetamilide. The maximum production of CDA-X in crude enzyme from JI-02 was observed in the presence of 1% colloidal chitin at 37°C and pH 6.4 after 120 h of incubation. Potent enzyme activity of CDA-X was determined toward pNP-acetamilide, demonstrating that optimal pH, temperature and ionic strength of the CDA-X were assessed to be 7.0, 52°C and 125 mM, respectively. Unexpectedly, Nacetylglucosamine (GlcNAc) was not fully converted by the action of CDA-X to glucosamine (GlcN) under the established conditions. Further study on enzyme activity toward chitin-oligosaccharides consisting of multi-N-acetylglucosamine (GlcNAc)n, n=2-5 may be necessary to elucidate the mode of action which requires the minimum size of (GlcNAc)n. However, our data suggest that CDA-X can convert chitin to chitosan with the maximum yield of approximately 0.08g/L during the fermentation of the strain in the presence of chitin. Furthermore, we found that crude enzyme showed the significant chitosanolytic activity. Taken together, our data suggest that the strain JI-02 may be a potential candidate as a particular strain for better understating of chitin catabolic pathway.

고대 금속상감에 관한 시론

임지영(Lim, ji-young) 부산고고학회 2016 고고광장 Vol.- No.18

금속상감은 바탕 금속에 홈을 만들어 홈 속에 바탕 금속과는 다른 금속을 물리적인 힘으로 감입하는 금공장식 기법이다. 본고는 상감홈과 상감선 등 제작에 관련된 여러 요소를 바탕으로 삼국시대와 일본 고분시대 출토 유물을 분류하고 기법상 차이와 유사점 등을 비교함으로써 고대 한일 금속상감의 제작공방과 그 계보를 상정하기 위한 시론이다. 금속상감은 연마라는 최종 제작과정과 부식이라는 금속의 특성으로 인해 육안관찰만으로는 제작 기법의 특징 파악이 곤란하다. 따라서 필자는 마이크로스코프와 X선 장치를 이용하여 상감유물의 기술적 특징을 파악하고 제작실험 비교를 통해 고대 금속상감 기법의 복원을 시도하였다. 그 결과, 상감홈의 경우 기존의 금공 연구를 통해 지적되어 왔던 축조와 모조기법의 양자가 존재하는 한편, 이제까지 언급되지 않았던 상감선의 제작기법에 있어서 단조 이외에 감기나 꼬기, 접기와 같은 다양한 제작기법이 존재한다는 것을 확인할 수 있었다. 각 기법의 사례에서는 시기와 지역차가 확인된다. 상감홈과 상감선 제작기법의 기술적 특징은 유라시아 대륙에서 그 원류를 찾을 수 있다. 이는 백제, 신라, 가야, 그리고 일본열도에 이르는 세선세공 기법의 전파루트와 상응하고 금제 보요의 기원과도 관련된다. 근년 발굴 조사된 러시아 초기철기 시대 상감유물, 그리고 후한대 중국 상감명문대도와 비교하여 각 기법 조합의 시기차와 지역차를 통해 고대한일 상감에 이르는 계보가 모조기법의 홈과 감기나 꼬기기법의 선을 특징으로 하는 <북방루 트>, 그리고 축조기법의 홈과 단조선을 특징으로 하는 <중국루트>의 가설을 제시하고자 한다. The metal inlaying technique is to putting gold or silver into a carved wire of the based metal with physical power. In this paper, based on the various elements such as quality of metal, inlaid groove and inlaid wire, presume the manufacture of workshop of the metal inlaying and its system by classifying the artifacts of the Three-Kingdom Period of the Korean Peninsula and Kofun Period of Japan and comparing the similarities and differences between them. It is hard to apprehend the feature of its technique with the naked eye because of polishing and corrosion. Therefore, I grasp the technical character by observing them with macroscopy as well as microscope, X-ray and restore the metal inlaying technique with comparing it with production experiment. As a result, in case of inlaid groove, there are lined-carving and triangled-carving that is commonly indicated in bronze artifacts. In case of inlaid wire, there are various technique such as winding, twisting, folding except hammering that is not indicated so far. It has got time and regional differences in example of each techniques. The feature of the technique of inlaid groove and inlaid wire is found in Eurasia. It corresponds to the diffusion route of the filigree technique to Baekje, Silla and Japan. By comparing its route connected with the origin of the golden ornament with the inlaid artifacts of Russian Early Iron Age and Chinese inlaid inscription sword in West Han Dynasty, abstract time and regional differences of the combination of the technique. Based on this, I propose a hypothesis that there are two different routes to the ancient Korea and Japan, one in the Northern-route; groove of the lined-carving and winded or twisted wire, the other in Chinese route; groove of triangled-carving and hammering wire.

D-Amphetamine이 니코틴성 흥분작용에 의한 카테콜아민 분비작용에 미치는 영향

임건한,서유석,민선영,임지연,김용직,나광문,임동윤 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.1

본 연구의 목적은 d-arphetamine이 흰쥐의 적출부신 관류모델에서 니코틴 수용체 흥분에 의한 카테콜아민(CA) 유리작용에 미치는 영향을 검색하여 그 작용기전을 규명하고자 하였다. D-amphetamine은 흰쥐 부신정맥내로 60분간 관류시 d-amphetamine자체는 약한 CA 분비작용을 나타내었으나, d-amphetamine (30 μM)을 비롯한 강력한 neuronal nicotine 수용체 작용제인 cytisine (50 μM) 및 epibatidine (30 μM)에 의한 CA 유리작용을 처음 4-10분 동안만 유의하게 증강시켰다. 또한, d-amphetamine (30 μM)은 60분간 부신정맥 내로 관류한 상태에서 dihydropyridine L-형 칼슘통로 개방약물인 Bay-K-8644 (10 μM)과 세포질내 칼슘저장고에서 Ca^(2+) ATPase 억제제인 cyclopiazonic acid (10 μM)의 CA 유리작용을 처음 4분간만 유의하게 증강시켰다. 그러나, 고농도의 d-amphetamine (500 μM)은 상기한 모든 분비촉진제의 CA분비작용을 오히려 억제하였다. 이와 같은 연구결과로 보면, 흰쥐 관류 부신수질에서 d-amphetamine은 낮은 농도에서는 콜린성 니코틴 수용체 흥분에 의한 카테콜아민 분비반응을 증강시키지만, 고농도에서는 오히려 억제적으로 작용함을 시사한다. 따라서, d-amphetamine은 용량에 따라서 흰쥐 적출 관류부신수질의 니코틴 수용체의 작용제 및 길항제로 이중 작용(dual action)을 나타내는 것으로 생각된다. 이러한 d-amphetamine의 작용은 흰쥐 부신수질 크롬친화세포의 dihydropyridine계 L-형 칼슘통로의 활성화 및 세포 내 칼슘저장고로부터 칼슘유리작용과 관련성이 있는 것으로 사료된다. The purpose of the present study was to examine the effect of d-amphetamine on CA release evoked by nocotinic receptor stimulation from the isolated perfused model of the rat adrenal gland, and to establish its mechanism of action. D-amphetamine(30 μM), when perfused into an adrenal vein of the rat adrenal gland for 60 min, enhanced the CA secretory responses evoked by ACh (5.32 mM), nicotine (30 μM), cytisine (50 μM, a selective neuronal nicotinic Nn-receptor agonist) and epibatidine (30 nM, a selective neuronal nicotinic Nn receptor agonist) only for the first period (4~10 min), although it alone has weak effect on CA secretion. Moreover, d-amphetamine (30 μM) in to an adrenal vein for 60 min also augmented the CA release evoked by BAY-K-8644, an activator of the dihydropyridine L-type Ca^(2+) channels, and cyclopiazonic acid, an inhibitor of cytoplasmic Ca^(2+) ATPase only for the first peroid (4 min). However, in the presence rather inhibited the CA secretory responses evoked by the above all of secretagogues. Taken together, these experimental results suggest that d-amphetamine at a low concentration enhances the CA secretion from the rat adrenal medulla evoked by stimulation of cholinergic nicotininc receptors, but at a high concentration it rather inhibits them. It semms that d-amphetamine has dual action acting as both agonist and antagonist at nicotinic receptors of the isolated perfused rat adrenal medulla, which are might be dependent on the concentration. It is also thought that these actions of d-amphetamine are probably relevant to the activation of the dihydropyridine L-type Ca^(2+) channels located on the rat adrenomedullary chromaffin cell membrane and release of Ca^(2+) from the cytoplasmic store.

Proteome Analysis of Nodule Development in both Sinpaldalkong2 and SS2-2

Lim,Chae-Woo,Park,Ji-Young,Hwang,Cheol-Ho 한국작물학회 2003 한국작물학회 학술발표대회 논문집 Vol.2003 No.-

[P8-249] Capsanthin, the Main Compounds in Red Paprika Fruit (Capsicum annuum L.), Prevents H<SUB>2</SUB>O<SUB>2</SUB>-Induced Inhibition of Gap-Junction Intercellular Communication

Ji?Sun Kim,Jiyun Ahn,Sun-hye Lim,Suna Kim,Tae-Youl Ha 한국식품영양과학회 2010 한국식품영양과학회 학술대회발표집 Vol.2010 No.10

석유/천연가스 매장량의 분류 및 평가방법

임종세,김지영 한국해양대학교 해양과학기술연구소 2001 硏究論文集 Vol.10 No.1

It is essential for future planning that governments and industry have a clear assessment of the quantities of petroleum available for production and quantities which are anticipated to become available within a practical time frame through additional field development, technological advances, or exploration. This paper describes the petroleum reserves classification and estimating methods based on the SPE/WPC (1997) definition. Reserves are those quantities of petroleum which are anticipated to be commercially recovered from known accumulations from a given date forward. Reserve estimating methods usually are categorized into analogy, volumetric and performance techniques. The performance techniques are subdivided into simulation studies, material balance calculations, and decline trend analysis. Reserve can be estimated using either deterministic or probabilistic methods. This paper can be helpful to understand petroleum reserve estimation and evaluate the reserves in oil & gas development projects properly.

일부 성장기 학생 혈중 연농도의 성별 및 연령별 분포

임재언,강은용,최병선,서지영,홍연표,장임원,박정덕 중앙대학교 의과대학 의과학연구소 2000 中央醫大誌 Vol.25 No.2

국내 직업무용단의 운영실태 및 발전방안 모색

임혜자,안지혜,이성노 韓國舞踊敎育學會 2004 韓國舞踊敎育學會誌 Vol.15 No.1

With the observation that civic and provincial dance troupes are remarkably active in the sphere of dance in each region of Korea, the purpose of this study was to present a more reasonable plan for managing professional dance troupes. We undertook this study by examining the operational problems, and compensation issues of dance troupes. For this study, several professional dance troupes in Korea (five civic dance troupes, plus one national troupe: the UBC Ballet Troupe) were selected as subjects. The results of the study are as follows: Firstly, the management of professional dance troupes needs to be improved and in particular, the issue of salary is most urgent. Secondly, corporate bodies are opposed to the transformation of their troupes and suggested that if change is indeed needed that management of a troupe be entrusted to a nongovernmental organization within two years. Meanwhile, public dance troupes approved of the plan and desired that the system be implemented within one year. Thirdly, the management of the troupes should be given over to professional artists and specialist aligned with the troupes. Fourthly, public group members, especially women members firmly believed that their own group should be generally improved. They also believed that the expansion of production costs was the most urgent issue requiring attention In addition, troupe members estimated that the standard of their contribution to the development of the art was average, and they would leave the matter to the direction of the art director. In short, for the development of professional dance troupes, the present system of the dance troupes should be transformed to a civil and consigned management system operated by experts, and the terms of salary, living conditions and the problem of expanding production costs should all be ameliorated.

항암제 젬시타빈의 경구용 제제 개발을 위한 전략수립

임지호,황지숙,이경록,이은주,조정원 충남대학교 약학대학 의약품개발연구소 2011 藥學論文集 Vol.26 No.-