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      • 젊은 남자에게 발생한 통상성 간질성 폐렴과 동반된 폐암 1예

        박종숙,이준혁,박성우,장안수,박춘식,박재성,백상현,고은석,신화균 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

        Usual interstitial pneumonia(UIP) is relatively rare disease of lung parenchyme under the age of 50. Lung cancer is reported to occur as a complication of UIP, but has not been reported in young age patient with UIP in Korea. A 35-year-old man was admitted to the hospital because of dyspnea, cough and mild fever. He had been suffered from dyspnea during 3 years. The dyspnea worsened recent 1 month ago. He had been treated with pneumonia at another hospital during 4 months before this admission. Chest radiographs and High resolution CT showed subpleural and basal dominant reticular opacities in both lung with no change until now. He was smoker and his occupation was car engine-man dealing with benzene. UIP is suspected by history and radiologic findings. Operation for open lung biopsy was performed to obtain lung specimen via video-assisted thoracoscopic surgery. Patient's pathologic examination showed UIP combined with adenocarcinoma in RLL superior segment and posterobasal segment and RLL lobectomy was done. After operation, the patient has been in cancer free condition so far. We report a case of UIP combined with lung cancer in young man with brief review of the literature.

      • KCI등재
      • SCOPUSKCI등재

        김치유래 젖산균의 균체지방산 분석을 이용한 분류학적 연구

        이정숙,정민철,김우식,이근철,김홍중,박찬선,이헌주,주윤정,이근종,안종석,박완,박용하,민태익 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.2

        표준균주를 포함한 230여개의 김치유래 젖산균에 대한 균체지방산(FAMEs)을 분석하였다. FAMEs profiles는 Euclidian Distance 17.5에 의해 7개의 Major Cluster와 1개의 Single Cluster로 나뉘어졌다. 이중 A, B, C 및 Cluster는 Leuconostoc속으로 분석되어졌고, F는 Lactobacillus속으로 분석되어졌다. 그리고 E와 G cluster는 두개의 Genus가 혼재되어 나타났으며 보충적인 연구가 필요하다. 앞으로 김치유래 젖산균의 균체지방산 분석결과를 기반으로 한 데이타베이스에 95가지 탄소원을 이용하는 수치분류학적 접근방법 및 Pyrolysis Mass Spectrometry 등의 화학적 분석 방법과 분자친화적 연구를 통한 종합적 분류정보 체계가 갖추어지면 젖산균의 신속, 정확한 동정 및 연구에 활발히 이용되어질 것이다. Two hundreds and thirty lactic acid bacteria, mostly isolated from Kimchi, including type strains were sued for analysis of cellular fatty acids. The 230 test strains were recoverd in 7 major and 1 single clusters defined a Euclidian distance of 17.5. These aggregate taxa were equivalent to the genus Leuconostoc (aggregate group A, B, C and D), and the genera Leuconostoc and Lactobacillus (aggregate group G). It is concluded as evident that FAMEs (Fatty Acid Methyl Esters) profile of cell can be used as a criterion in classification of lactic acid bacterial from kimchi. Additional comparative taxonomic studies need to be carried out on well chosen representative strains to determine the most appropriate methods of value.

      • 개에서 피지선 과형성의 진단 및 치료 증례

        박희서,손화영,정성목,송근호,조종기,이영원,신상태,김명철,김덕환,박성준 충남대학교 수의과대학 동물의과학연구소 2004 動物醫科學硏究誌 Vol.12 No.-

        An eleven year old castrated male Maltese was presented to the Veterinary Medical Teaching Hospital of Chungnam National University. In physical examination, approximately 0.5 cm round mass was observed on tail base. This small elevated mass has also shown alopecic and firm configuration. It was differentially diagnosed as sebaceous adenoma and hyperplasia by fine needle aspiration. After surgical removal, the sample was diagnosed as sebaceous hyperplasia by histopathological examination. It has not yet shown any signs of recurrence and prognosis has teen good.

      • 체육전공 대학생들의 건강에 대한 지식, 태도 및 행위간의 관련성 비교

        박종성,이창근,유영규 명지대학교 예술체육대학연구소 2004 藝體能論集 Vol.15 No.-

        The present writer carried out of a survey on physical education majors of some junior colleges to grasp their levels of health information and attitudes/behaviors to good health, and to compare and analyze the correlations between them with a view to developing health-improving programs for junior colleges, thereby affording a basic material for health guidance. The survey was conducted with questionnaires addressed to 567 male students and 263 female students of four junior colleges in Seoul and Kyeonggi province. As s result of statistical examination of the survey, the present writer has reached the following conclusions. 1. The level of health informaion obtained 14.98±4.54 points out of a possible 22, indicating 68.1% of correct information. There was no significant statistical difference between the information levels of male and female students. 2. The level of their attitude to health obtained 14.97±3.66 points out of a possible 22, indicating 68.0% of correct attitude. There was no big statistical difference between the attitude levels of male and female students. 3. The level of their behavioral action to good health obtained 10.56±3.52 points out of a possible 22, indicating on an average 48.0% of correct behavior. Regarding smoking, drinking,coffee intake, sexually transmitted disease, sexual relations, physical checkup, etc., female students indicaed by far the more desirable results than male students statistically. 4. In the comparison and analysis of correlations between the survey subjects' health information and attitudes/behaviors to good health, significant statistical difference were observed in the correlations between the subjects' health information attitudes(r=0.498, p<.01). 5. Comparing and analyzing the correlations between the survey subjects' health information and attitudes/behaviors to good health, the present writer has found more significant statistical correlations between their health information and attitudes(M:r=0.502,p<.01; F:r=0.497, p<0.1), attitudes and behavioral action(M:r=0.218, p<0.1; F:r=0.478,p<0.1),health information and behavioral action(M:r=0.203, p<0.1; F:r=0.349, p<0.1) of male students than of female students. In other words, compared with female students, male students failed to live up to their health information more frequently than female students. As This study was limited to the physical education majors of some junior colleges, a retional generalization cannot be deduced from the outcome of the survey. A survey is required, therefore, based on a larger scale. Again, since the basic health items were limited to eleven kinds, this study necessarily does not include all gealth problems; more comprehensive surveys are yet to be carried out. As a result of this survey, however, it was ascertained that there is relatively little correlation between the subjects' health information and their attitudes, attitudes and behavioral action, informaion and behavoioral action. Hopefully, health behavior-focused health education based on adequate health informaion should be carried out, instead of health guidance overemphasizing health information alone.

      • 성인형 당뇨병에서의 심혈관 합병증과 지질대사와의 관계

        박헌진,안정기,이종선,김영건 충남대학교 의과대학 지역사회의학연구소 1989 충남의대잡지 Vol.16 No.1

        Hypwelipiswmia is commonly observed in the diabetics, especially with cardiovascular complications. We studied lipid profiles and cardiovascular complication in the 191 adult onset DM patients. The results are as follows: 1. The age distribution was from 24 years old to 82 years old. Male patients were 99 persons, famale patients were 92 persons. The mean disease duration was less than 2 years in the 77 patients, more than 5 years in the 79 patients. 2. Upon the classification between sexes, the mean age was 55±1(SEM) years in the male group, 53±1(SEM) years in the female group. The mean disease durtion was 6.4±1(SEM) years in the female group, longer in the male group (P<0.05). The triglyceride level was 210±16(SEM)㎎% in the male group, 214±13(SEM)㎎% in the female group. The fasting blood sugar level was 147±6(SEM)㎎/dl in the male group, 158±8(SEM)㎎/dl n the female group. The cholesterol level was 229±5(SEM)㎎/dl in the male group, 248±5(SEM)㎎/dl in the female group, higher in the female group (P<0.05). 3. The cardiovascurlar complicatioin (Hypertension, Myocardial infarction, Myocardial ischemia, Angina, Gangrene, Proliferative retinopathy) were present in the 60 patients from 191 patients. Hypertension was present in the 48 patients, and the most prevalent. The mean age and carrdiovascular complication were higher in the more than 5 years of mean disease duration group(mean age 57.99±1.14(SEM)㎎ year) than less than 5 years group(mean age 52.12±0.10(SEM)㎎ year) (P<0.001, P<0.01). 4. The mean disease duration (7.40±1.01(SEM) years), mean triglyceride levels(271±1.01(SEM)㎎%), and mean cholestrerol levels( 257±8㎎.dl) in the cardiovascularly complicated group were higher than those of non-complicated group (P<0.01). 5. The triglycerdie level was high in the obese group (230±14SEM㎎%) than non-obese group (184±15SEM㎎%) (P<0.05). The obese patients were more prevalent in the female group than male group significantly. 6. Considering obesity and cardiovascular complications, the triglyceride value was higher in the obese complicated group(300±30SEM㎎%) than obese non-complicated (197±14SEM㎎ %) or non-obese non-complicated (168±13SEM㎎ %) group (P<0.001). The cholesterol level was higher in the obese complicated group (267±10SEM㎎/dl) than obese non-complicated (230±5SEM㎎/dl) or non-obese non-complicated group(229±7SEM㎎/dl) (P<0.05). 7. Classifying upon insulin response pattern, the obese patients were found in the response pattern, low response pattern, flat type pattern(no response pattern) in the decreasing number of order (P<0.01). The cardiovascular complications were found in the low response group, response group, and flat type pattern (no response) in the decreasing number of order ( P<0.05). The combined cases of obesity and cardiovascular complications were found in the low response group, response group and flat type group(no response) pattern in the decreasing number of order (P<0.01). The mean disease duration was longer in the flat type group (no response) (4.48±0.6SEM years) than the response group(2.43±0.90SEM years) (P<0.05). The mean triglyceride value was higher in the response group (267.38±154.75SEM㎎%) than the flat type(no response group) (198.35±154.05SD㎎%) (P<0.05). So, we conclude that in the NIDDM, obesity control(die control, ideal body weight mainterice, and hyperlipidemia control) is essential for better DM control and cardiovascular complication control.

      • TiO_(2)-SiO_(2) 나노 복합미립자의 합성

        박진구,송영상,김종길,김호건 한양대학교 이학기술연구소 2005 이학기술연구지 Vol.8 No.-

        TEOS(tetrethyl orthosilicate)로 부터 제조된 구형의 SiO_(2) 미립자를 TiOCl_(2) 수용액과 반응시켜 SiO_(2) 표면에 10~20㎚ 두께의 균일한 TiO_(2)막이 형성된 TiO_(2)-SiO_(2) 복합미립자를 합성하였다. X-선 회절 분석결과 합성초기의 복합체 TiO_(2)는 비정질 상태이지만 700℃이상의 열처리에 의하여 anatase결정상이 나타났고 900℃이상에서 rutile결정상으로 전이됨을 확인하였다. TiO_(2)-SiO_(2) composite particle in which the homogeneous TiO_(2) layer with width of 10~20㎚ was formed on the SiO_(2) surface by the reaciton of the spherical SiO_(2) particale in TiOCl_(2) solution As the resulte of XRD analysis the phase of TiO_(2) coated on SiO_(2) sphere was noncrystalline state however it was changed to anatase crystal state by heating at 700℃and th anatase phase was transfomed to reile phase at the aboce 900℃

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